| miR-509-5p promotes colorectal cancer cell ferroptosis by targeting SLC7A11. | miR-509-5p promotes colorectal cancer cell ferroptosis by targeting SLC7A11.
Elrebehy MA, Abdelghany TM, Elshafey MM, Gomaa MH, Doghish AS. | 06/21/2023 |
| Expression of miR-187 and miR-509-3p in serum of primary hepatocellular carcinoma patients and its evaluation of prognosis. | Expression of miR-187 and miR-509-3p in serum of primary hepatocellular carcinoma patients and its evaluation of prognosis.
Dai G, Shen S, Liu Y, Ma X, Fang Y, Weng Y, Li C. | 02/5/2022 |
| MiR-509-3-5p inhibits colon cancer malignancy by suppressing GTSE1. | MiR-509-3-5p inhibits colon cancer malignancy by suppressing GTSE1.
Li K. | 11/22/2021 |
| Through conducting multivariate analysis in the training test, it was identified that the high expression of hsa-miR-509 and hsa-miR-542 were independent poor prognostic factors, whereas that of hsa-miR-146a and hsa-miR-3667 had a trend to be favorable factors. A 4-miRNA signature was constructed by these miRNAs considering the weight of each. | A 4-microRNA signature for survival prognosis in pediatric and adolescent acute myeloid leukemia.
Zhu R, Lin W, Zhao W, Fan F, Tang L, Hu Y. | 06/27/2020 |
| miR-509-5p was associated with worse overall survival in patients with pancreatic cancer and was identified as an independently selected predictor of mortality. Our findings suggest that miR-509-5p and miR-1243 might be novel chemotherapeutic targets and serve as biomarkers in pancreatic cancer. | miR-509-5p and miR-1243 increase the sensitivity to gemcitabine by inhibiting epithelial-mesenchymal transition in pancreatic cancer.
Hiramoto H, Muramatsu T, Ichikawa D, Tanimoto K, Yasukawa S, Otsuji E, Inazawa J., Free PMC Article | 12/29/2018 |
| MiR-509-5p exerted tumor-suppressive effects on breast cancer progression and metastasis via targeting SOD2 in vitro | MicroRNA-509-5p functions as an anti-oncogene in breast cancer via targeting SOD2.
Song YH, Wang J, Nie G, Chen YJ, Li X, Jiang X, Cao WH. | 08/11/2018 |
| MiR-509-3p could sensitize ovarian cancer cells to cisplatin treatment. | miR-509-3p promotes cisplatin-induced apoptosis in ovarian cancer cells through the regulation of anti-apoptotic genes.
Chen W, Du J, Li X, Su J, Huang Y, Ding N, Zhang M, Jiang S. | 07/28/2018 |
| The present study revealed the tumor suppressive role of miR-509-5p in non-small cell lung cancer (NSCLC) by targeting YWHAG, suggesting that miR-509-5p/YWHAG axis might be considered as a novel and potential target for clinical diagnosis and therapeutics of NSCLC. | MiR-509-5p suppresses the proliferation, migration, and invasion of non-small cell lung cancer by targeting YWHAG.
Wang P, Deng Y, Fu X. | 06/10/2017 |
| Our findings strongly demonstrate that miR-509 functions as tumor suppressor in TNBC BC cells through, at least partially, suppressing the secretion of TNF-alpha. | Overexpression of miR-509 Increases Apoptosis and Inhibits Invasion via Suppression of Tumor Necrosis Factor-α in Triple-Negative Breast Cancer Hs578T Cells.
Zhang G, Liu Z, Han Y, Wang X, Yang Z., Free PMC Article | 03/18/2017 |
| Results suggest that microRNA miRNA-509-5p negatively regulates c-mdm2 proto-oncogene protein (MDM2) expression via targeting the 3' untranslated region (3'-UTR) of genes. | Inhibition of invasion and migration of prostate cancer cells by miRNA-509-5p via targeting MDM2.
Tian XM, Luo YZ, He P, Li J, Ma ZW, An Y. | 03/18/2017 |
| The miR-509-5p could bind to the 3' untranslational regions of FOXM1 mRNA. | The Tumor Suppressive Role of MiRNA-509-5p by Targeting FOXM1 in Non-Small Cell Lung Cancer.
Ma N, Zhang W, Qiao C, Luo H, Zhang X, Liu D, Zang S, Zhang L, Bai J. | 02/18/2017 |
| Mir509 has a critical role in brain metastasis of breast cancer by modulating the RhoC-TNF-alpa network. | miR-509 suppresses brain metastasis of breast cancer cells by modulating RhoC and TNF-α.
Xing F, Sharma S, Liu Y, Mo YY, Wu K, Zhang YY, Pochampally R, Martinez LA, Lo HW, Watabe K., Free PMC Article | 12/12/2015 |
| The expression of miR-509-5p in HeLa and QGY-7703 cells repressed the expression of Mdm2, subsequently enhancing its p53-activating effects. | Mir-509-5p joins the Mdm2/p53 feedback loop and regulates cancer cell growth.
Ren ZJ, Nong XY, Lv YR, Sun HH, An PP, Wang F, Li X, Liu M, Tang H., Free PMC Article | 09/15/2015 |
| miR-509-5p plays an important role in renal cell carcinoma by inhibiting cell proliferation and migration and by promoting cell apoptosis. | Tumor suppressive miR-509-5p contributes to cell migration, proliferation and antiapoptosis in renal cell carcinoma.
Zhang WB, Pan ZQ, Yang QS, Zheng XM. | 04/1/2015 |