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    MAVS mitochondrial antiviral signaling protein [ Homo sapiens (human) ]

    Gene ID: 57506, updated on 6-Oct-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Activation of the RIG-I/MAVS Signaling Pathway during Human Adenovirus Type 3 Infection Impairs the Pro-Inflammatory Response Induced by Secondary Infection with Staphylococcus aureus.

    Activation of the RIG-I/MAVS Signaling Pathway during Human Adenovirus Type 3 Infection Impairs the Pro-Inflammatory Response Induced by Secondary Infection with Staphylococcus aureus.
    Chen J, Wang Q, Zhong B, Zheng H, Wang D, Huang X, Liu L, Liu T., Free PMC Article

    05/23/2024
    The Interaction between SARS-CoV-2 Nucleocapsid Protein and UBC9 Inhibits MAVS Ubiquitination by Enhancing Its SUMOylation.

    The Interaction between SARS-CoV-2 Nucleocapsid Protein and UBC9 Inhibits MAVS Ubiquitination by Enhancing Its SUMOylation.
    Huang C, Yin Y, Pan P, Huang Y, Chen S, Chen J, Wang J, Xu G, Tao X, Xiao X, Li J, Yang J, Jin Z, Li B, Tong Z, Du W, Liu L, Liu Z., Free PMC Article

    01/11/2024
    MAVS signaling is required for preventing persistent chikungunya heart infection and chronic vascular tissue inflammation.

    MAVS signaling is required for preventing persistent chikungunya heart infection and chronic vascular tissue inflammation.
    Noval MG, Spector SN, Bartnicki E, Izzo F, Narula N, Yeung ST, Damani-Yokota P, Dewan MZ, Mezzano V, Rodriguez-Rodriguez BA, Loomis C, Khanna KM, Stapleford KA., Free PMC Article

    08/7/2023
    Dengue Virus 2 NS2B Targets MAVS and IKKepsilon to Evade the Antiviral Innate Immune Response.

    Dengue Virus 2 NS2B Targets MAVS and IKKε to Evade the Antiviral Innate Immune Response.
    Nie Y, Deng D, Mou L, Long Q, Chen J, Wu J., Free PMC Article

    06/2/2023
    CircPVT1 promotes ER-positive breast tumorigenesis and drug resistance by targeting ESR1 and MAVS.

    CircPVT1 promotes ER-positive breast tumorigenesis and drug resistance by targeting ESR1 and MAVS.
    Yi J, Wang L, Hu GS, Zhang YY, Du J, Ding JC, Ji X, Shen HF, Huang HH, Ye F, Liu W., Free PMC Article

    05/17/2023
    Retinoic acid-inducible gene 1 (RIG-1) and IFN-beta promoter stimulator-1 (IPS-1) significantly down-regulated in the severe coronavirus disease 2019 (COVID-19).

    Retinoic acid-inducible gene 1 (RIG-1) and IFN-β promoter stimulator-1 (IPS-1) significantly down-regulated in the severe coronavirus disease 2019 (COVID-19).
    Nahavandi-Parizi P, Kariminik A, Montazeri M., Free PMC Article

    02/4/2023
    The effects of NLRP3 and MAVS gene polymorphisms on the risk of asthma: A case-control study.

    The effects of NLRP3 and MAVS gene polymorphisms on the risk of asthma: A case-control study.
    Xulong C, Li Z, Tongjin Y., Free PMC Article

    01/11/2023
    RNA binding by ADAR3 inhibits adenosine-to-inosine editing and promotes expression of immune response protein MAVS.

    RNA binding by ADAR3 inhibits adenosine-to-inosine editing and promotes expression of immune response protein MAVS.
    Raghava Kurup R, Oakes EK, Manning AC, Mukherjee P, Vadlamani P, Hundley HA., Free PMC Article

    10/22/2022
    The protein arginine methyltransferase PRMT9 attenuates MAVS activation through arginine methylation.

    The protein arginine methyltransferase PRMT9 attenuates MAVS activation through arginine methylation.
    Bai X, Sui C, Liu F, Chen T, Zhang L, Zheng Y, Liu B, Gao C., Free PMC Article

    09/3/2022
    Tankyrases inhibit innate antiviral response by PARylating VISA/MAVS and priming it for RNF146-mediated ubiquitination and degradation.

    Tankyrases inhibit innate antiviral response by PARylating VISA/MAVS and priming it for RNF146-mediated ubiquitination and degradation.
    Xu YR, Shi ML, Zhang Y, Kong N, Wang C, Xiao YF, Du SS, Zhu QY, Lei CQ., Free PMC Article

    07/2/2022
    A conventional immune regulator mitochondrial antiviral signaling protein blocks hepatic steatosis by maintaining mitochondrial homeostasis.

    A conventional immune regulator mitochondrial antiviral signaling protein blocks hepatic steatosis by maintaining mitochondrial homeostasis.
    Fu J, Hu F, Ma T, Zhao WJ, Tian H, Zhang Y, Hu M, Zhou J, Zhang Y, Jian C, Ji YX, Zhang XJ, Jiang J, She ZG, Cheng X, Zhang P, Bai L, Yang J, Li H.

    03/5/2022
    The Ebola Virus Interferon Antagonist VP24 Undergoes Active Nucleocytoplasmic Trafficking.

    The Ebola Virus Interferon Antagonist VP24 Undergoes Active Nucleocytoplasmic Trafficking.
    Harrison AR, David CT, Rawlinson SM, Moseley GW., Free PMC Article

    01/29/2022
    MicroRNA-33/33* inhibit the activation of MAVS through AMPK in antiviral innate immunity.

    MicroRNA-33/33* inhibit the activation of MAVS through AMPK in antiviral innate immunity.
    Liu D, Tan Q, Zhu J, Zhang Y, Xue Y, Song Y, Liu Y, Wang Q, Lai L., Free PMC Article

    01/29/2022
    Next Generation Exome Sequencing of Pediatric Asthma Identifies Rare and Novel Variants in Candidate Genes.

    Next Generation Exome Sequencing of Pediatric Asthma Identifies Rare and Novel Variants in Candidate Genes.
    Bogari NM, Amin AA, Rayes HH, Abdelmotelb A, Taher MM, Al-Allaf FA, Bouazzaoui A, O'Gorman L, Holloway JW., Free PMC Article

    10/30/2021
    Human Herpesvirus 6B U26 Inhibits the Activation of the RLR/MAVS Signaling Pathway.

    Human Herpesvirus 6B U26 Inhibits the Activation of the RLR/MAVS Signaling Pathway.
    Jiang X, Tang T, Guo J, Wang Y, Li P, Chen X, Wang L, Wen Y, Jia J, Emanuela G, Hu B, Chen S, Yao K, Li L, Tang H., Free PMC Article

    09/11/2021
    Suppression of innate immune signaling molecule, MAVS, reduces radiation-induced bystander effect.

    Suppression of innate immune signaling molecule, MAVS, reduces radiation-induced bystander effect.
    Jia R, Chen Y, Jia C, Hu B, Du Y.

    08/28/2021
    Arginine monomethylation by PRMT7 controls MAVS-mediated antiviral innate immunity.

    Arginine monomethylation by PRMT7 controls MAVS-mediated antiviral innate immunity.
    Zhu J, Li X, Cai X, Zha H, Zhou Z, Sun X, Rong F, Tang J, Zhu C, Liu X, Fan S, Wang J, Liao Q, Ouyang G, Xiao W.

    08/28/2021
    O-Linked N-Acetylglucosamine Modification of Mitochondrial Antiviral Signaling Protein Regulates Antiviral Signaling by Modulating Its Activity.

    O-Linked N-Acetylglucosamine Modification of Mitochondrial Antiviral Signaling Protein Regulates Antiviral Signaling by Modulating Its Activity.
    Seo J, Park YS, Kweon TH, Kang J, Son S, Kim HB, Seo YR, Kang MJ, Yi EC, Lee YH, Kim JH, Park B, Yang WH, Cho JW., Free PMC Article

    07/17/2021
    Beneficial bacteria activate type-I interferon production via the intracellular cytosolic sensors STING and MAVS.

    Beneficial bacteria activate type-I interferon production via the intracellular cytosolic sensors STING and MAVS.
    Gutierrez-Merino J, Isla B, Combes T, Martinez-Estrada F, Maluquer De Motes C., Free PMC Article

    07/3/2021
    Dual targeting of RIG-I and MAVS by MARCH5 mitochondria ubiquitin ligase in innate immunity.

    Dual targeting of RIG-I and MAVS by MARCH5 mitochondria ubiquitin ligase in innate immunity.
    Park YJ, Oanh NTK, Heo J, Kim SG, Lee HS, Lee H, Lee JH, Kang HC, Lim W, Yoo YS, Cho H.

    06/12/2021
    USP18 positively regulates innate antiviral immunity by promoting K63-linked polyubiquitination of MAVS.

    USP18 positively regulates innate antiviral immunity by promoting K63-linked polyubiquitination of MAVS.
    Hou J, Han L, Zhao Z, Liu H, Zhang L, Ma C, Yi F, Liu B, Zheng Y, Gao C., Free PMC Article

    06/5/2021
    The RNA binding protein Quaking represses host interferon response by downregulating MAVS.

    The RNA binding protein Quaking represses host interferon response by downregulating MAVS.
    Liao KC, Chuo V, Fagg WS, Bradrick SS, Pompon J, Garcia-Blanco MA., Free PMC Article

    05/8/2021
    Mitochondrial DUT-M potentiates RLR-mediated antiviral signaling by enhancing VISA and TRAF2 association.

    Mitochondrial DUT-M potentiates RLR-mediated antiviral signaling by enhancing VISA and TRAF2 association.
    Weng GX, Ling T, Hou W, Li SN, Chen T, Zhang Z, Wang DD, Xu LG.

    04/24/2021
    Mitochondrial reactive zones in antiviral innate immunity.

    Mitochondrial reactive zones in antiviral innate immunity.
    Yasukawa K, Koshiba T.

    04/17/2021
    SIRT5 impairs aggregation and activation of the signaling adaptor MAVS through catalyzing lysine desuccinylation.

    SIRT5 impairs aggregation and activation of the signaling adaptor MAVS through catalyzing lysine desuccinylation.
    Liu X, Zhu C, Zha H, Tang J, Rong F, Chen X, Fan S, Xu C, Du J, Zhu J, Wang J, Ouyang G, Yu G, Cai X, Chen Z, Xiao W., Free PMC Article

    04/13/2021
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