| Shifts in receptors during submergence of an encephalitic arbovirus. | Shifts in receptors during submergence of an encephalitic arbovirus.
Li W, Plante JA, Lin C, Basu H, Plung JS, Fan X, Boeckers JM, Oros J, Buck TK, Anekal PV, Hanson WA, Varnum H, Wells A, Mann CJ, Tjang LV, Yang P, Reyna RA, Mitchell BM, Shinde DP, Walker JL, Choi SY, Brusic V, Llopis PM, Weaver SC, Umemori H, Chiu IM, Plante KS, Abraham J., Free PMC Article | 08/19/2024 |
| The role of Pcdh10 in neurological disease and cancer. | The role of Pcdh10 in neurological disease and cancer.
Zhen Y, Pavez M, Li X., Free PMC Article | 08/1/2023 |
| E3 ubiquitin ligase RNF180 prevents excessive PCDH10 methylation to suppress the proliferation and metastasis of gastric cancer cells by promoting ubiquitination of DNMT1. | E3 ubiquitin ligase RNF180 prevents excessive PCDH10 methylation to suppress the proliferation and metastasis of gastric cancer cells by promoting ubiquitination of DNMT1.
Zhang N, Gao X, Yuan Q, Fu X, Wang P, Cai F, Liu H, Zhang J, Liang H, Nie Y, Deng J., Free PMC Article | 05/22/2023 |
| Miz1 promotes KRAS-driven lung tumorigenesis by repressing the protocadherin Pcdh10. | Miz1 promotes KRAS-driven lung tumorigenesis by repressing the protocadherin Pcdh10.
Yang J, Hou C, Wang H, Perez EA, Do-Umehara HC, Dong H, Arunagiri V, Tong F, Van Scoyk M, Cho M, Liu X, Ge X, Winn RA, Ridge KM, Wang X, Chandel NS, Liu J., Free PMC Article | 01/28/2023 |
| PCDH10 exerts tumor-suppressor functions through modulation of EGFR/AKT axis in colorectal cancer. | PCDH10 exerts tumor-suppressor functions through modulation of EGFR/AKT axis in colorectal cancer.
Jao TM, Fang WH, Ciou SC, Yu SL, Hung YL, Weng WT, Lin TY, Tsai MH, Yang YC. | 05/22/2021 |
| HOTAIR Induces Methylation of PCDH10, a Tumor Suppressor Gene, by Regulating DNMT1 and Sponging with miR-148b in Gastric Adenocarcinoma. | HOTAIR Induces Methylation of PCDH10, a Tumor Suppressor Gene, by Regulating DNMT1 and Sponging with miR-148b in Gastric Adenocarcinoma.
Seo SI, Yoon JH, Byun HJ, Lee SK., Free PMC Article | 02/13/2021 |
| PCDH10 inhibits invasion of lymphoma cells by regulating beta-catenin. | PCDH10 inhibits invasion of lymphoma cells by regulating β-catenin.
Zhang QK, Li HY, Wei XF, Feng YF. | 10/3/2020 |
| Disruption of PCDH10 and TNRC18 Genes due to a Balanced Translocation. | Disruption of PCDH10 and TNRC18 Genes due to a Balanced Translocation.
Zamariolli M, Di-Battista A, Moysés-Oliveira M, de Mello CB, de Paula Ramos MA, Liehr T, Melaragno MI. | 09/19/2020 |
| Quantitation Analysis of PCDH10 Methylation in Adolescent Idiopathic Scoliosis Using Pyrosequencing Study. | Quantitation Analysis of PCDH10 Methylation in Adolescent Idiopathic Scoliosis Using Pyrosequencing Study.
Shi B, Mao S, Xu L, Li Y, Sun X, Liu Z, Zhu Z, Qiu Y. | 08/29/2020 |
| Study found elevated promoter methylation and decreased expression of PCDH10 and PCDH17 in advanced gastric lesions, suggesting that elevated PCDH10 and PCDH17 methylation may be an early event in gastric carcinogenesis. | Methylation and Expression of Nonclustered Protocadherins Encoding Genes and Risk of Precancerous Gastric Lesions in a High-Risk Population.
Wu S, Zhang Y, Zhang L, Ma JL, Zhou T, Li ZX, Liu WD, Li WQ, You WC, Pan KF. | 09/28/2019 |
| Study shows for that the methylation status of PCDH10 can predict prognosis in pancreatic ductal adenocarcinoma (PDAC) patients with a significant impact on the outcome in terms of progression-free survival. High levels of PCDH10 promoter methylation could be useful to identify patients at high risk of PDAC disease progression. | High methylation levels of PCDH10 predict poor prognosis in patients with pancreatic ductal adenocarcinoma.
Curia MC, Fantini F, Lattanzio R, Tavano F, Di Mola F, Piantelli M, Battista P, Di Sebastiano P, Cama A., Free PMC Article | 09/14/2019 |
| PCDH10 hypermethylation were found in 54.2% (58/107) of DLBCL cases, but only 12.5% (1/8) in reactive lymph node/follicular hyperplasia. | Clinical significance of PCDH10 promoter methylation in diffuse large B-cell lymphoma.
Huang W, Xue X, Shan L, Qiu T, Guo L, Ying J, Lu N., Free PMC Article | 07/28/2018 |
| This study provides insights into the tumorigenesis and progression of hepatocellular carcinoma (HCC), and puts forward the novel hypothesis that PCDH10 could be a new biomarker for HCC, or that combined with other molecular markers could increase the specificity and sensitivity of diagnostic tests for HCC. Restoration of PCDH10 could be a valuable therapeutic target for HCC. | PCDH10 gene inhibits cell proliferation and induces cell apoptosis by inhibiting the PI3K/Akt signaling pathway in hepatocellular carcinoma cells.
Ye M, Li J, Gong J., Free PMC Article | 03/10/2018 |
| we found that the malignant character of GISTs was initiated and amplified by PCDH10 in a process regulated by HOTAIR. In summary, our findings imply that PCDH10 and HOTAIR may be useful markers of disease progression and therapeutic targets. | Promoter methylation of PCDH10 by HOTAIR regulates the progression of gastrointestinal stromal tumors.
Lee NK, Lee JH, Kim WK, Yun S, Youn YH, Park CH, Choi YY, Kim H, Lee SK., Free PMC Article | 03/3/2018 |
| we found that long noncoding RNA (lncRNA) MALAT1 binds EZH2, suppresses the tumor suppressor PCDH10, and promotes gastric cellular migration and invasion | MALAT1 long ncRNA promotes gastric cancer metastasis by suppressing PCDH10.
Qi Y, Ooi HS, Wu J, Chen J, Zhang X, Tan S, Yu Q, Li YY, Kang Y, Li H, Xiong Z, Zhu T, Liu B, Shao Z, Zhao X., Free PMC Article | 12/9/2017 |
| These findings suggest that Pcdh10 may influence subcellular actin cytoskeletal organization and axon-axon interactions in the course of familial amyloidotic polyneuropathy | Overexpression of Protocadherin-10 in Transthyretin-Related Familial Amyloidotic Polyneuropathy.
Gonçalves NP, Martins D, Saraiva MJ. | 05/13/2017 |
| PCDH10 methylation in serum is a potential prognostic biomarker for prostate cancer. | Prognostic Value of Protocadherin10 (PCDH10) Methylation in Serum of Prostate Cancer Patients.
Deng QK, Lei YG, Lin YL, Ma JG, Li WP., Free PMC Article | 11/12/2016 |
| Study found that hypermethylation of CpG probes in the promoter regions of HOXA9 and PCDH10 was associated with mature B-cell neoplasms. | Global measures of peripheral blood-derived DNA methylation as a risk factor in the development of mature B-cell neoplasms.
Wong Doo N, Makalic E, Joo JE, Vajdic CM, Schmidt DF, Wong EM, Jung CH, Severi G, Park DJ, Chung J, Baglietto L, Prince HM, Seymour JF, Tam C, Hopper JL, English DR, Milne RL, Harrison SJ, Southey MC, Giles GG. | 10/22/2016 |
| Results suggest that protocadherin 10 (PCDH10)-Dishevelled, EGL-10 and Pleckstrin domain containing 1 (DEPDC1)-caspase signaling may be a novel regulatory axis in endometrial endometrioid carcinoma (EEC) development. | Protocadherin 10 inhibits cell proliferation and induces apoptosis via regulation of DEP domain containing 1 in endometrial endometrioid carcinoma.
Yang Y, Jiang Y, Jiang M, Zhang J, Yang B, She Y, Wang W, Deng Y, Ye Y. | 09/10/2016 |
| Data show that protocadherin 10 (PCDH10) over-expression could significantly induce cell apoptosis, and restrain proliferation, invasion and migration ability of BXPC-3 pancreatic cancer cells. | [Protocadherin 10 (PCDH10) inhibits the proliferation, invasion and migration ability of BXPC-3 pancreatic cancer cells].
Qiu C, Bu X, Hu D, Jiang Z. | 07/30/2016 |
| Our present findings suggested that the hypermethylated CpG site counts of PCDH10 DNA promoter for evaluating the prognosis of GC was reasonable by using the D-BGS | Evaluating the clinical feasibility: The direct bisulfite genomic sequencing for examination of methylated status of protocadherin10 (PCDH10) promoter to predict the prognosis of gastric cancer.
Hou YC, Deng JY, Zhang RP, Xie XM, Cui JL, Wu WP, Hao XS, Liang H. | 07/16/2016 |
| PCDH10 methylation is a potential biomarker that predicts a poor prognosis after curative resection of pathological stage I non-small-cell lung cancer. | Prognostic signature of protocadherin 10 methylation in curatively resected pathological stage I non-small-cell lung cancer.
Harada H, Miyamoto K, Yamashita Y, Taniyama K, Mihara K, Nishimura M, Okada M., Free PMC Article | 07/16/2016 |
| PCDH10 antagonized MM cell proliferation via the downregulation of Wnt/beta-catenin/BCL-9 signaling, whereas PCDH10 repressed the expression of AKT to promote the expression of GSK3beta and then to restrain the activation of beta-catenin | PCDH10 inhibits cell proliferation of multiple myeloma via the negative regulation of the Wnt/β-catenin/BCL-9 signaling pathway.
Xu Y, Yang Z, Yuan H, Li Z, Li Y, Liu Q, Chen J. | 03/26/2016 |
| These results suggest an important role of p53 in regulating tumor cell migration through activating PCDH10 expression. | PCDH10, a novel p53 transcriptional target in regulating cell migration.
Shi D, Murty VV, Gu W., Free PMC Article | 12/19/2015 |
| Aberrant methylation of PCDH10 predicts worse biochemical recurrence-free survival in patients with prostate cancer after radical prostatectomy. | Aberrant methylation of PCDH10 predicts worse biochemical recurrence-free survival in patients with prostate cancer after radical prostatectomy.
Wang L, Xie PG, Lin YL, Ma JG, Li WP., Free PMC Article | 03/21/2015 |