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    SYT13 synaptotagmin 13 [ Homo sapiens (human) ]

    Gene ID: 57586, updated on 11-Apr-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Role of synaptotagmin 13 (SYT13) in promoting breast cancer and signaling pathways.

    Role of synaptotagmin 13 (SYT13) in promoting breast cancer and signaling pathways.
    Zhang YD, Zhong R, Liu JQ, Sun ZX, Wang T, Liu JT.

    10/25/2023
    The highly expressed calcium-insensitive synaptotagmin-11 and synaptotagmin-13 modulate insulin secretion.

    The highly expressed calcium-insensitive synaptotagmin-11 and synaptotagmin-13 modulate insulin secretion.
    Ofori JK, Karagiannopoulos A, Barghouth M, Nagao M, Andersson ME, Salunkhe VA, Zhang E, Wendt A, Eliasson L., Free PMC Article

    08/20/2022
    Synaptotagmin 13 Is Highly Expressed in Estrogen Receptor-Positive Breast Cancer.

    Synaptotagmin 13 Is Highly Expressed in Estrogen Receptor-Positive Breast Cancer.
    Ichikawa T, Shibata M, Inaishi T, Soeda I, Kanda M, Hayashi M, Takano Y, Takeuchi D, Tsunoda N, Kodera Y, Kikumori T., Free PMC Article

    10/30/2021
    Synaptotagmin 13 is neuroprotective across motor neuron diseases.

    Synaptotagmin 13 is neuroprotective across motor neuron diseases.
    Nizzardo M, Taiana M, Rizzo F, Aguila Benitez J, Nijssen J, Allodi I, Melzi V, Bresolin N, Comi GP, Hedlund E, Corti S., Free PMC Article

    06/12/2021
    Identification SYT13 as a novel biomarker in lung adenocarcinoma.

    Identification SYT13 as a novel biomarker in lung adenocarcinoma.
    Zhang L, Fan B, Zheng Y, Lou Y, Cui Y, Wang K, Zhang T, Tan X.

    05/1/2021
    Silencing of synaptotagmin 13 inhibits tumor growth through suppressing proliferation and promoting apoptosis of colorectal cancer cells.

    Silencing of synaptotagmin 13 inhibits tumor growth through suppressing proliferation and promoting apoptosis of colorectal cancer cells.
    Li Q, Zhang S, Hu M, Xu M, Jiang X., Free PMC Article

    10/10/2020
    SYT13 levels were significantly associated with shorter peritoneal recurrence-free survival (PRFS) and overall survival in patients with gastric cancer; positive levels of SYT13 and CEA mRNA demonstrated the highest hazards ratio for peritoneal recurrence

    The levels of SYT13 and CEA mRNAs in peritoneal lavages predict the peritoneal recurrence of gastric cancer.
    Nakanishi K, Kanda M, Umeda S, Tanaka C, Kobayashi D, Hayashi M, Yamada S, Kodera Y.

    04/18/2020
    SYT13 expression in gastric cancer is associated with peritoneal metastases.

    Synaptotagmin XIII expression and peritoneal metastasis in gastric cancer.
    Kanda M, Shimizu D, Tanaka H, Tanaka C, Kobayashi D, Hayashi M, Takami H, Niwa Y, Yamada S, Fujii T, Sugimoto H, Kodera Y.

    03/9/2019
    These studies combine to suggest that SYT13 is a liver tumor suppressor gene and that its function may be mediated through pathways implicated in mesenchymal to epithelial transition

    Exogenous expression of synaptotagmin XIII suppresses the neoplastic phenotype of a rat liver tumor cell line through molecular pathways related to mesenchymal to epithelial transition.
    Jahn JE, Best DH, Coleman WB.

    01/1/2011
    Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)

    Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
    Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR., Free PMC Article

    06/30/2010
    human SYT13 functions as a liver tumor suppressor gene that complements a molecular defect in rat liver tumor cells resulting in a normalized cellular phenotype in vitro and suppression of tumorigenicity in vivo

    Re-expression of tumorigenicity after attenuation of human synaptotagmin 13 in a suppressed microcell hybrid cell line.
    Jahn JE, Coleman WB.

    01/21/2010
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