CAMSAP3, a microtubule orientation regulator, plays a vital role in manifesting differentiation-dependent characteristics in keratinocytes. | CAMSAP3, a microtubule orientation regulator, plays a vital role in manifesting differentiation-dependent characteristics in keratinocytes. Kobori M, Abe J, Saito R, Hirai Y. | 02/4/2024 |
CAMSAP3 negatively regulates lung cancer cell invasion and angiogenesis through nucleolin/HIF-1alpha mRNA complex stabilization. | CAMSAP3 negatively regulates lung cancer cell invasion and angiogenesis through nucleolin/HIF-1α mRNA complex stabilization. Seephan S, Sasaki SI, Wattanathamsan O, Singharajkomron N, He K, Ucche S, Kungsukool S, Petchjorm S, Chantaravisoot N, Wongkongkathep P, Hayakawa Y, Pongrakhananon V. | 04/26/2023 |
Rab14/MACF2 complex regulates endosomal targeting during cytokinesis. | Rab14/MACF2 complex regulates endosomal targeting during cytokinesis. Gibieža P, Peterman E, Hoffman HK, Van Engeleburg S, Skeberdis VA, Prekeris R., Free PMC Article | 09/18/2021 |
Findings suggest that CAMSAP3 functions to protect lung carcinoma cells against EMT by suppressing Akt activity via microtubule regulation and that CAMSAP3 loss promotes EMT in these cells. | Loss of CAMSAP3 promotes EMT via the modification of microtubule-Akt machinery. Pongrakhananon V, Wattanathamsan O, Takeichi M, Chetprayoon P, Chanvorachote P. | 01/11/2020 |
data suggest that CDH23-C is a CAMSAP3/Marshalin-binding protein that can modify MT networks indirectly through its interaction with CAMSAP3/Marshalin. | Cadherin 23-C Regulates Microtubule Networks by Modifying CAMSAP3's Function. Takahashi S, Mui VJ, Rosenberg SK, Homma K, Cheatham MA, Zheng J., Free PMC Article | 05/12/2018 |
CAMSAP3-dependent Golgi vesicle clustering and graded microtubule dynamics | CAMSAP3-dependent microtubule dynamics regulates Golgi assembly in epithelial cells. Wang J, Xu H, Jiang Y, Takahashi M, Takeichi M, Meng W. | 10/28/2017 |
in mammalian intestinal epithelial cells, the spectraplakin ACF7 (also known as MACF1) specifically binds to CAMSAP3 and is required for the apical localization of CAMSAP3-decorated microtubule minus ends. | Control of apico-basal epithelial polarity by the microtubule minus-end-binding protein CAMSAP3 and spectraplakin ACF7. Noordstra I, Liu Q, Nijenhuis W, Hua S, Jiang K, Baars M, Remmelzwaal S, Martin M, Kapitein LC, Akhmanova A. | 08/5/2017 |
ACF7, a member of the spectraplakin family of cytoskeletal crosslinking proteins, interacts with Nezha (also called CAMSAP3) at the minus ends of noncentrosomal microtubules and anchors them to actin filaments. | The CAMSAP3-ACF7 Complex Couples Noncentrosomal Microtubules with Actin Filaments to Coordinate Their Dynamics. Ning W, Yu Y, Xu H, Liu X, Wang D, Wang J, Wang Y, Meng W. | 06/24/2017 |
These findings demonstrate that apically localized CAMSAP3 determines the proper orientation of microtubules, and in turn that of organelles, in mature mammalian epithelial cells. | CAMSAP3 orients the apical-to-basal polarity of microtubule arrays in epithelial cells. Toya M, Kobayashi S, Kawasaki M, Shioi G, Kaneko M, Ishiuchi T, Misaki K, Meng W, Takeichi M., Free PMC Article | 06/28/2016 |
The CKK domain binds microtubules and represents a domain that evolved with the metazoa. | The CKK domain (DUF1781) binds microtubules and defines the CAMSAP/ssp4 family of animal proteins. Baines AJ, Bignone PA, King MD, Maggs AM, Bennett PM, Pinder JC, Phillips GW. | 09/19/2011 |
KIAA1543 is a non-centrosomal minus end binding protein. It is termed Nezha(a character in Chinese mythic novel (Journey to the West)). | Anchorage of microtubule minus ends to adherens junctions regulates epithelial cell-cell contacts. Meng W, Mushika Y, Ichii T, Takeichi M. | 04/14/2009 |