Promotion of DNA end resection by BRCA1-BARD1 in homologous recombination. | Promotion of DNA end resection by BRCA1-BARD1 in homologous recombination. Salunkhe S, Daley JM, Kaur H, Tomimatsu N, Xue C, Raina VB, Jasper AM, Rogers CM, Li W, Zhou S, Mojidra R, Kwon Y, Fang Q, Ji JH, Badamchi Shabestari A, Fitzgerald O, Dinh H, Mukherjee B, Habib AA, Hromas R, Mazin AV, Wasmuth EV, Olsen SK, Libich DS, Zhou D, Zhao W, Greene EC, Burma S, Sung P. | 10/11/2024 |
Germline BARD1 variants predispose to mesothelioma by impairing DNA repair and calcium signaling. | Germline BARD1 variants predispose to mesothelioma by impairing DNA repair and calcium signaling. Novelli F, Yoshikawa Y, Vitto VAM, Modesti L, Minaai M, Pastorino S, Emi M, Kim JH, Kricek F, Bai F, Onuchic JN, Bononi A, Suarez JS, Tanji M, Favaron C, Zolondick AA, Xu R, Takanishi Y, Wang Z, Sakamoto G, Gaudino G, Grzymski J, Grosso F, Schrump DS, Pass HI, Atanesyan L, Smout J, Savola S, Sarin KY, Abolhassani H, Hammarström L, Pan-Hammarström Q, Giorgi C, Pinton P, Yang H, Carbone M., | 08/7/2024 |
Structural dynamics of clinically-reported VUS in the BARD1 ARD-BRCT region to predict the molecular basis of alterations. | Structural dynamics of clinically-reported VUS in the BARD1 ARD-BRCT region to predict the molecular basis of alterations. Barua SA, Choudhary RK, Gawde J, Mishra N, Varma AK. | 06/27/2024 |
BLM and BRCA1-BARD1 coordinate complementary mechanisms of joint DNA molecule resolution. | BLM and BRCA1-BARD1 coordinate complementary mechanisms of joint DNA molecule resolution. Tsukada K, Jones SE, Bannister J, Durin MA, Vendrell I, Fawkes M, Fischer R, Kessler BM, Chapman JR, Blackford AN. | 02/22/2024 |
Germline pathogenic variants in neuroblastoma patients are enriched in BARD1 and predict worse survival. | Germline pathogenic variants in neuroblastoma patients are enriched in BARD1 and predict worse survival. Kim J, Vaksman Z, Egolf LE, Kaufman R, Evans JP, Conkrite KL, Danesh A, Lopez G, Randall MP, Dent MH, Farra LM, Menghani NL, Dymek M, Desai H, Hausler R, Hicks B, Auvil JG, Gerhard DS, Hakonarson H, Maxwell KN, Cole KA, Pugh TJ, Bosse KR, Khan J, Wei JS, Maris JM, Stewart DR, Diskin SJ., Free PMC Article | 01/12/2024 |
BARD1 germline variants induce haploinsufficiency and DNA repair defects in neuroblastoma. | BARD1 germline variants induce haploinsufficiency and DNA repair defects in neuroblastoma. Randall MP, Egolf LE, Vaksman Z, Samanta M, Tsang M, Groff D, Evans JP, Rokita JL, Layeghifard M, Shlien A, Maris JM, Diskin SJ, Bosse KR., Free PMC Article | 01/12/2024 |
BRCA1-BARD1 combines multiple chromatin recognition modules to bridge nascent nucleosomes. | BRCA1-BARD1 combines multiple chromatin recognition modules to bridge nascent nucleosomes. Burdett H, Foglizzo M, Musgrove LJ, Kumar D, Clifford G, Campbell LJ, Heath GR, Zeqiraj E, Wilson MD., Free PMC Article | 11/18/2023 |
Exome sequencing identifies breast cancer susceptibility genes and defines the contribution of coding variants to breast cancer risk. | Exome sequencing identifies breast cancer susceptibility genes and defines the contribution of coding variants to breast cancer risk. Wilcox N, Dumont M, González-Neira A, Carvalho S, Joly Beauparlant C, Crotti M, Luccarini C, Soucy P, Dubois S, Nuñez-Torres R, Pita G, Gardner EJ, Dennis J, Alonso MR, Álvarez N, Baynes C, Collin-Deschesnes AC, Desjardins S, Becher H, Behrens S, Bolla MK, Castelao JE, Chang-Claude J, Cornelissen S, Dörk T, Engel C, Gago-Dominguez M, Guénel P, Hadjisavvas A, Hahnen E, Hartman M, Herráez B, SGBCC Investigators, Jung A, Keeman R, Kiechle M, Li J, Loizidou MA, Lush M, Michailidou K, Panayiotidis MI, Sim X, Teo SH, Tyrer JP, van der Kolk LE, Wahlström C, Wang Q, Perry JRB, Benitez J, Schmidt MK, Schmutzler RK, Pharoah PDP, Droit A, Dunning AM, Kvist A, Devilee P, Easton DF, Simard J., Free PMC Article | 10/19/2023 |
Association of BARD1 and BRIP1 Gene Polymorphisms with the Risk of Uveal Melanoma. | Association of BARD1 and BRIP1 Gene Polymorphisms with the Risk of Uveal Melanoma. Mukhana L, Aissa AA, Ahmed AAM, Saakyan SV, Tsygankov AY, Blagonravov ML, Azova MM. | 08/25/2023 |
BRCA1-associated RING domain-1 (BARD1) loss and GBP1 expression enhance sensitivity to DNA damage in Ewing sarcoma. | BRCA1-associated RING domain-1 (BARD1) loss and GBP1 expression enhance sensitivity to DNA damage in Ewing sarcoma. Maurer LM, Daley JD, Mukherjee E, Venier RE, Julian CM, Bailey NG, Jacobs MF, Kumar-Sinha C, Raphael H, Periyapatna N, Weiss K, Janeway KA, Mody R, Lucas PC, McAllister-Lucas LM, Bailey KM., Free PMC Article | 07/27/2023 |
Enhancing the BOADICEA cancer risk prediction model to incorporate new data on RAD51C, RAD51D, BARD1 updates to tumour pathology and cancer incidence. | Enhancing the BOADICEA cancer risk prediction model to incorporate new data on RAD51C, RAD51D, BARD1 updates to tumour pathology and cancer incidence. Lee A, Mavaddat N, Cunningham A, Carver T, Ficorella L, Archer S, Walter FM, Tischkowitz M, Roberts J, Usher-Smith J, Simard J, Schmidt MK, Devilee P, Zadnik V, Jürgens H, Mouret-Fourme E, De Pauw A, Rookus M, Mooij TM, Pharoah PP, Easton DF, Antoniou AC., Free PMC Article | 12/3/2022 |
BARD1 mystery: tumor suppressors are cancer susceptibility genes. | BARD1 mystery: tumor suppressors are cancer susceptibility genes. Hawsawi YM, Shams A, Theyab A, Abdali WA, Hussien NA, Alatwi HE, Alzahrani OR, Oyouni AAA, Babalghith AO, Alreshidi M., Free PMC Article | 06/11/2022 |
Apparent regional differences in the spectrum of BARD1 pathogenic variants in Spanish population and importance of copy number variants. | Apparent regional differences in the spectrum of BARD1 pathogenic variants in Spanish population and importance of copy number variants. Benito-Sánchez B, Barroso A, Fernández V, Mercadillo F, Núñez-Torres R, Pita G, Pombo L, Morales-Chamorro R, Cano-Cano JM, Urioste M, González-Neira A, Osorio A., Free PMC Article | 06/11/2022 |
CRL4-DCAF8L2 E3 ligase promotes ubiquitination and degradation of BARD1. | CRL4-DCAF8L2 E3 ligase promotes ubiquitination and degradation of BARD1. Deng J, Zhang T, Liu F, Han Q, Li Q, Guo X, Ma Y, Li L, Shao G. | 05/28/2022 |
Computational structural assessment of BReast CAncer type 1 susceptibility protein (BRCA1) and BRCA1-Associated Ring Domain protein 1 (BARD1) mutations on the protein-protein interface. | Computational structural assessment of BReast CAncer type 1 susceptibility protein (BRCA1) and BRCA1-Associated Ring Domain protein 1 (BARD1) mutations on the protein-protein interface. Thirumal Kumar D, Udhaya Kumar S, Jain N, Sowmya B, Balsekar K, Siva R, Kamaraj B, Sidenna M, George Priya Doss C, Zayed H. | 05/14/2022 |
RNAi Screening Uncovers a Synthetic Sick Interaction between CtIP and the BARD1 Tumor Suppressor. | RNAi Screening Uncovers a Synthetic Sick Interaction between CtIP and the BARD1 Tumor Suppressor. Bolck HA, Przetocka S, Meier R, von Aesch C, Zurfluh C, Hänggi K, Spegg V, Altmeyer M, Stebler M, Nørrelykke SF, Horvath P, Sartori AA, Porro A., Free PMC Article | 04/16/2022 |
BRCA1-BARD1 regulates transcription through modulating topoisomerase IIbeta. | BRCA1-BARD1 regulates transcription through modulating topoisomerase IIβ. Bunch H, Jeong J, Kang K, Jo DS, Cong ATQ, Kim D, Kim D, Cho DH, Lee YM, Chen BPC, Schellenberg MJ, Calderwood SK., Free PMC Article | 03/5/2022 |
RNA assay identifies a previous misclassification of BARD1 c.1977A>G variant. | RNA assay identifies a previous misclassification of BARD1 c.1977A>G variant. Rofes P, Pineda M, Feliubadaló L, Menéndez M, de Cid R, Gómez C, Montes E, Capellá G, Brunet J, Del Valle J, Lázaro C., Free PMC Article | 02/5/2022 |
BARD1 Autoantibody Blood Test for Early Detection of Ovarian Cancer. | BARD1 Autoantibody Blood Test for Early Detection of Ovarian Cancer. Pilyugin M, Ratajska M, Stukan M, Concin N, Zeillinger R, Irminger-Finger I., Free PMC Article | 02/5/2022 |
SIRT2 promotes BRCA1-BARD1 heterodimerization through deacetylation. | SIRT2 promotes BRCA1-BARD1 heterodimerization through deacetylation. Minten EV, Kapoor-Vazirani P, Li C, Zhang H, Balakrishnan K, Yu DS., Free PMC Article | 01/29/2022 |
RNF19A-mediated ubiquitination of BARD1 prevents BRCA1/BARD1-dependent homologous recombination. | RNF19A-mediated ubiquitination of BARD1 prevents BRCA1/BARD1-dependent homologous recombination. Zhu Q, Huang J, Huang H, Li H, Yi P, Kloeber JA, Yuan J, Chen Y, Deng M, Luo K, Gao M, Guo G, Tu X, Yin P, Zhang Y, Su J, Chen J, Lou Z., Free PMC Article | 12/18/2021 |
The BRCA1/BARD1 ubiquitin ligase and its substrates. | The BRCA1/BARD1 ubiquitin ligase and its substrates. Witus SR, Stewart MD, Klevit RE., Free PMC Article | 11/27/2021 |
Is it a wrap? Nucleosome interactions of the BRCA1-binding partner, BARD1, steal the scene. | Is it a wrap? Nucleosome interactions of the BRCA1-binding partner, BARD1, steal the scene. Morris JR. | 10/16/2021 |
Mechanisms of BRCA1-BARD1 nucleosome recognition and ubiquitylation. | Mechanisms of BRCA1-BARD1 nucleosome recognition and ubiquitylation. Hu Q, Botuyan MV, Zhao D, Cui G, Mer E, Mer G., Free PMC Article | 10/9/2021 |
BARD1 reads H2A lysine 15 ubiquitination to direct homologous recombination. | BARD1 reads H2A lysine 15 ubiquitination to direct homologous recombination. Becker JR, Clifford G, Bonnet C, Groth A, Wilson MD, Chapman JR. | 10/9/2021 |