TRPV4 mediates IL-1-induced Ca(2+) signaling, ERK activation and MMP expression.
Wang Q, Ji C, Ali A, Ding I, Wang Y, McCulloch CA.

Impact of TRP Channels on Extracellular Matrix Remodeling: Focus on TRPV4 and Collagen.
Wang Q, Ji C, Smith P, McCulloch CA., Free PMC Article

Inflammation-induced TRPV4 channels exacerbate blood-brain barrier dysfunction in multiple sclerosis.
Hansen CE, Kamermans A, Mol K, Berve K, Rodriguez-Mogeda C, Fung WK, van Het Hof B, Fontijn RD, van der Pol SMA, Michalick L, Kuebler WM, Kenkhuis B, van Roon-Mom W, Liedtke W, Engelhardt B, Kooij G, Witte ME, de Vries HE., Free PMC Article

Inflammation, lipid dysregulation, and transient receptor potential cation channel subfamily V member 4 signaling perpetuate chronic vulvar pain.
Bekauri T, Fischer S, Honn KV, Maddipati KR, Love T, Little C, Wood RW, Bonham AD, Linder MA, Yule DI, Emanuelle C, Falsetta ML., Free PMC Article

TRPV4 in adipose tissue ameliorates diet-induced obesity by promoting white adipocyte browning.
Zhang Y, Xue J, Zhu W, Wang H, Xi P, Tian D.

Hypothermia Attenuates Neurotoxic Microglial Activation via TRPV4.
Fukuda N, Toriuchi K, Mimoto R, Aoki H, Kakita H, Suzuki Y, Takeshita S, Tamura T, Yamamura H, Inoue Y, Hayashi H, Yamada Y, Aoyama M.

Fatty acid metabolism promotes TRPV4 activity in lung microvascular endothelial cells in pulmonary arterial hypertension.
Philip N, Yun X, Pi H, Murray S, Hill Z, Fonticella J, Perez P, Zhang C, Pathmasiri W, Sumner S, Servinsky L, Jiang H, Huetsch JC, Oldham WM, Visovatti S, Leary PJ, Gharib SA, Brittain E, Simpson CE, Le A, Shimoda LA, Suresh K.

TRPV4 Regulates the Development of Psoriasis by Controlling Adenosine Triphosphate Expression in Keratinocytes and the Neuroimmune System.
Amalia SN, Baral H, Fujiwara C, Uchiyama A, Inoue Y, Yamazaki S, Ishikawa M, Kosaka K, Sekiguchi A, Yokoyama Y, Ogino S, Torii R, Hosoi M, Shibasaki K, Motegi SI.

Cell-specific NFIA upregulation promotes epileptogenesis by TRPV4-mediated astrocyte reactivity.
Kong S, Chen TX, Jia XL, Cheng XL, Zeng ML, Liang JY, He XH, Yin J, Han S, Liu WH, Fan YT, Zhou T, Liu YM, Peng BW., Free PMC Article

Deletion of Endothelial TRPV4 Protects Heart From Pressure Overload-Induced Hypertrophy.
Adapala RK, Katari V, Kanugula AK, Ohanyan V, Paruchuri S, Thodeti CK.,

Association of novel mutation in TRPV4 with familial nonsyndromic craniosynostosis with complete penetrance and variable expressivity.
Gayden T, Crevier-Sorbo G, Jawhar W, Saint-Martin C, Eveleigh R, Gilardino MS, Anastasio N, Trakadis Y, Bassenden AV, Berghuis AM, Jabado N, Dudley RWR.

Inhibition of TRPV4 remodels single cell polarity and suppresses the metastasis of hepatocellular carcinoma.
Liu J, Guo Y, Zhang R, Xu Y, Luo C, Wang R, Xu S, Wei L., Free PMC Article

TRPV4-Rho GTPase complex structures reveal mechanisms of gating and disease.
Kwon DH, Zhang F, McCray BA, Feng S, Kumar M, Sullivan JM, Im W, Sumner CJ, Lee SY., Free PMC Article

Structure of human TRPV4 in complex with GTPase RhoA.
Nadezhdin KD, Talyzina IA, Parthasarathy A, Neuberger A, Zhang DX, Sobolevsky AI., Free PMC Article

Activation of the Mechanosensitive Ion Channels Piezo1 and TRPV4 in Primary Human Healthy and Osteoarthritic Chondrocytes Exhibits Ion Channel Crosstalk and Modulates Gene Expression.
Steinecker-Frohnwieser B, Lohberger B, Toegel S, Windhager R, Glanz V, Kratschmann C, Leithner A, Weigl L., Free PMC Article

Astrocytic TRPV4 Channels and Their Role in Brain Ischemia.
Tureckova J, Hermanova Z, Marchetti V, Anderova M., Free PMC Article

TRPV4 channel is involved in HSV-2 infection in human vaginal epithelial cells through triggering Ca(2+) oscillation.
Jiang P, Li SS, Xu XF, Yang C, Cheng C, Wang JS, Zhou PZ, Liu SW., Free PMC Article

Pan-Cancer Analysis of the TRP Family, Especially TRPV4 and TRPC4, and Its Expression Correlated with Prognosis, Tumor Microenvironment, and Treatment Sensitivity.
Chen Z, Zhao Y, Tian Y, Cao R, Shang D., Free PMC Article

Skeletal dysplasia-causing TRPV4 mutations suppress the hypertrophic differentiation of human iPSC-derived chondrocytes.
Dicks AR, Maksaev GI, Harissa Z, Savadipour A, Tang R, Steward N, Liedtke W, Nichols CG, Wu CL, Guilak F., Free PMC Article

The temperature-sensitive receptors TRPV4 and TRPM8 have important roles in the pruritus of rosacea.
Zhou X, Su Y, Wu S, Wang H, Jiang R, Jiang X.

TRPV4 and the paradox of faster cellular migration rates in more viscous extracellular fluids.
So CL, Robitaille M, Monteith GR.

TRPV4 is not the molecular sensor for bacterial lipopolysaccharides-induced calcium signaling.
Wang Y, Hao Y, Jin J, Yi Z, Liu Y, Zhou H, Zhao G, Wen L, Dong H, Zhang Y, Zhang M, Jia Y, Han L, Xu H, Wang T, Feng J.

The Emerging Pro-Algesic Profile of Transient Receptor Potential Vanilloid Type 4.
White JPM, Cibelli M, Nagy I, Nilius B, McGeown JG.

Anti-Inflammatory Role of TRPV4 in Human Macrophages.
Atsumi Y, Toriyama M, Kato H, Nakamura M, Morita A, Takaishi M, Saito K, Tanaka M, Okada F, Tominaga M, Ishii KJ, Fujita F., Free PMC Article

Colonic TRPV4 overexpression is related to constipation severity.
Mihara H, Uchida K, Watanabe Y, Nanjo S, Sakumura M, Motoo I, Ando T, Minemura M, Muhammad JS, Yamamoto H, Itoh F, Yasuda I., Free PMC Article