| REL and BHLHE40 Variants Are Associated with IL-12 and IL-10 Responses and Tuberculosis Risk. | REL and BHLHE40 Variants Are Associated with IL-12 and IL-10 Responses and Tuberculosis Risk.
Shah JA, Warr AJ, Graustein AD, Saha A, Dunstan SJ, Thuong NTT, Thwaites GE, Caws M, Thai PVK, Bang ND, Chau TTH, Khor CC, Li Z, Hibberd M, Chang X, Nguyen FK, Hernandez CA, Jones MA, Sassetti CM, Fitzgerald KA, Musvosvi M, Gela A, Hanekom WA, Hatherill M, Scriba TJ, Hawn TR., Free PMC Article | 07/16/2022 |
| METTL3 restrains papillary thyroid cancer progression via m(6)A/c-Rel/IL-8-mediated neutrophil infiltration. | METTL3 restrains papillary thyroid cancer progression via m(6)A/c-Rel/IL-8-mediated neutrophil infiltration.
He J, Zhou M, Yin J, Wan J, Chu J, Jia J, Sheng J, Wang C, Yin H, He F., Free PMC Article | 12/4/2021 |
| NF-kappaB c-Rel Is Dispensable for the Development but Is Required for the Cytotoxic Function of NK Cells. | NF-κB c-Rel Is Dispensable for the Development but Is Required for the Cytotoxic Function of NK Cells.
Vicioso Y, Wong DP, Roy NK, Das N, Zhang K, Ramakrishnan P, Parameswaran R., Free PMC Article | 10/2/2021 |
| Association study between vitiligo and autoimmune-related genes CYP27B1, REL, TNFAIP3, IL2 and IL21. | Association study between vitiligo and autoimmune-related genes CYP27B1, REL, TNFAIP3, IL2 and IL21.
Martins LT, Frigeri HR, de Castro CCS, Mira MT. | 09/18/2021 |
| Pro-survival and anti-inflammatory roles of NF-kappaB c-Rel in the Parkinson's disease models. | Pro-survival and anti-inflammatory roles of NF-κB c-Rel in the Parkinson's disease models.
Wang Z, Dong H, Wang J, Huang Y, Zhang X, Tang Y, Li Q, Liu Z, Ma Y, Tong J, Huang L, Fei J, Yu M, Wang J, Huang F., Free PMC Article | 04/17/2021 |
| Constitutive expression of c-REL in uveal melanoma patients: correlation with clinicopathological parameters and patient outcome. | Constitutive expression of c-REL in uveal melanoma patients: correlation with clinicopathological parameters and patient outcome.
Singh MK, Singh L, Pushker N, Chosdol K, Bakhshi S, Meel R, Sen S, Kashyap S. | 03/27/2021 |
| A Matter of Choice: Inhibition of c-Rel Shifts Neuronal to Oligodendroglial Fate in Human Stem Cells. | A Matter of Choice: Inhibition of c-Rel Shifts Neuronal to Oligodendroglial Fate in Human Stem Cells.
Ruiz-Perera LM, Greiner JFW, Kaltschmidt C, Kaltschmidt B., Free PMC Article | 02/20/2021 |
| Human galectin-16 has a pseudo ligand binding site and plays a role in regulating c-Rel-mediated lymphocyte activity. | Human galectin-16 has a pseudo ligand binding site and plays a role in regulating c-Rel-mediated lymphocyte activity.
Si Y, Yao Y, Jaramillo Ayala G, Li X, Han Q, Zhang W, Xu X, Tai G, Mayo KH, Zhou Y, Su J. | 01/16/2021 |
| The c-Rel-c-Myc axis controls metabolism and proliferation of human T leukemia cells. | The c-Rel-c-Myc axis controls metabolism and proliferation of human T leukemia cells.
Li X, Luo G, Li T, Sun H, Wang W, Eiler E, Goldsmith JR, Chen YH., Free PMC Article | 10/10/2020 |
| c-Rel is involved in G2/M phase regulation, prevention of polyploidy and, consequently, chromosomal stability in human melanoma cells | c-Rel is a cell cycle modulator in human melanoma cells.
Priebe MK, Dewert N, Amschler K, Erpenbeck L, Heinzerling L, Schön MP, Seitz CS, Lorenz VN. | 06/27/2020 |
| Combined immunodeficiency in a patient with c-Rel deficiency. | Combined immunodeficiency in a patient with c-Rel deficiency.
Beaussant-Cohen S, Jaber F, Massaad MJ, Weeks S, Jones J, Alosaimi MF, Wallace J, Al-Herz W, Geha RS, Chou J., Free PMC Article | 05/23/2020 |
| The results of this study suggest a possible association of cow's milk proteins allergy with cRel G+7883T polymorphism | Association of REL Polymorphism with Cow's Milk Proteins Allergy in Pediatric Algerian Population.
Rahmoun N, El Mecherfi KE, Bouchetara A, Lardjem Hetraf S, Dahmani Amira C, Adda Neggaz L, Boudjema A, Zemani-Fodil F, Kheroua O. | 09/1/2018 |
| TAB1 was identified as a functional target of miR-134, and the expression of TAB1 was increased by the transcription factors of NF-kappaB1, c-Rel, and ELK1 via miR-134. | NF-κB1, c-Rel, and ELK1 inhibit miR-134 expression leading to TAB1 upregulation in paclitaxel-resistant human ovarian cancer.
Shuang T, Wang M, Zhou Y, Shi C, Wang D., Free PMC Article | 04/7/2018 |
| NOD2 up-regulates TLR2-mediated IL-23p19 expression via increasing c-Rel activation in Paneth cell-like cells | NOD2 up-regulates TLR2-mediated IL-23p19 expression via NF-κB subunit c-Rel in Paneth cell-like cells.
Tan G, Liang E, Liao K, Deng F, Zhang W, Chen Y, Xu J, Zhi F., Free PMC Article | 04/7/2018 |
| this study show that inhibition of c-Rel expression by siRNA reduced cord blood-derived B-, T-, and NK cell differentiation and expansion | Impact of C-rel inhibition of cord blood-derived B-, T-, and NK cells.
Fallahi S, Mohammadi SM, Tayefi Nasrabadi H, Alihemmati A, Samadi N, Gholami S, Shanehbandi D, Nozad Charoudeh H. | 10/14/2017 |
| Findings emphasize the importance of c-REL-signaling in a cellular model of cervical cancer particularly in terms of proliferation and resistance to chemotherapeutic agents. | CRISPR/Cas9-mediated knockout of c-REL in HeLa cells results in profound defects of the cell cycle.
Slotta C, Schlüter T, Ruiz-Perera LM, Kadhim HM, Tertel T, Henkel E, Hübner W, Greiner JFW, Huser T, Kaltschmidt B, Kaltschmidt C., Free PMC Article | 09/30/2017 |
| genetic association studies in population in India: Data suggest that common polymorphisms (SNPs) in CHGA promoter are associated with cardiometabolic disorders; c-Rel has a role in activating CHGA promoter haplotype 2 (variant T alleles at -1018 and -57 bp) under basal and pathophysiological conditions. (CHGA = chromogranin A; c-Rel = c-Rel proto-oncogene protein) | A haplotype variant of the human chromogranin A gene (CHGA) promoter increases CHGA expression and the risk for cardiometabolic disorders.
Subramanian L, Khan AA, Allu PKR, Kiranmayi M, Sahu BS, Sharma S, Khullar M, Mullasari AS, Mahapatra NR., Free PMC Article | 09/16/2017 |
| findings suggest that c-Rel might play a role in promoting the invasion of choriocarcinoma cells through PI3K/AKT signaling | c-Rel Promotes Invasion of Choriocarcinoma Cells via PI3K/AKT Signaling.
Sekiya Y, Yamamoto E, Niimi K, Nishino K, Nakamura K, Kotani T, Kajiyama H, Shibata K, Kikkawa F. | 06/24/2017 |
| miR-574 and REL interfere with apoptosis in prostate cancer stem cells. | Downregulation of microRNA‑574 in cancer stem cells causes recurrence of prostate cancer via targeting REL.
Lai X, Guo Y, Guo Z, Liu R, Wang X, Wang F. | 03/18/2017 |
| observations indicate that induced expression of miR-15b is modulated by c-Rel and CREB in response to JEV infection | Transcriptional regulation of miR-15b by c-Rel and CREB in Japanese encephalitis virus infection.
Zhu B, Ye J, Ashraf U, Li Y, Chen H, Song Y, Cao S., Free PMC Article | 03/4/2017 |
| Gene expression levels of Rel were deregulated in 49 B-cell chronic lymphocytic leukemia, 8 B-cell non-Hodgkin's lymphoma, 3 acute myeloid leukemia, 3 chronic myeloid leukemia, 2 hairy cell leukemia, 2 myelodysplastic syndrome, and 2 T-cell large granular lymphocytic leukemia patients in the post-Chernobyl period. | Deregulated Levels of the NF-κB1, NF-κB2, and Rel Genes in Ukrainian Patients with Leukemia and Lymphoma in the Post-Chernobyl Period.
Savlı H, Akkoyunlu RU, Çine N, Gluzman DF, Zavelevich MP, Sklyarenko LM, Koval SV, Sünnetçi D., Free PMC Article | 01/28/2017 |
| The REL rs842647 polymorphism may be a susceptibility factor for Behcet's Disease pathogenesis and skin lesions. | Genetic Variation in the REL Gene Increases Risk of Behcet's Disease in a Chinese Han Population but That of PRKCQ Does Not.
Chen F, Xu L, Zhao T, Xiao X, Pan Y, Hou S., Free PMC Article | 08/13/2016 |
| analysis of c-Rel nuclear expression and REL amplification and crosstalk between c-Rel and the p53 pathway reveals prognostic roles diffuse large B-cell lymphoma | Prognostic impact of c-Rel nuclear expression and REL amplification and crosstalk between c-Rel and the p53 pathway in diffuse large B-cell lymphoma.
Li L, Xu-Monette ZY, Ok CY, Tzankov A, Manyam GC, Sun R, Visco C, Zhang M, Montes-Moreno S, Dybkaer K, Chiu A, Orazi A, Zu Y, Bhagat G, Richards KL, Hsi ED, Choi WW, van Krieken JH, Huh J, Ponzoni M, Ferreri AJ, Møller MB, Wang J, Parsons BM, Winter JN, Piris MA, Pham LV, Medeiros LJ, Young KH., Free PMC Article | 08/6/2016 |
| Over-expression of nuclear NF-kappaB1 and c-Rel are strong risk factors associated with chemoresistance and the prognosis of serous epithelial ovarian cancer | Over-expression of nuclear NF-κB1 and c-Rel correlates with chemoresistance and prognosis of serous epithelial ovarian cancer.
Shuang T, Wang M, Zhou Y, Shi C. | 06/28/2016 |
| Thus, our studies support a role for c-Rel in processes crucial for keratinocyte integrity and malignant transformation such as adhesion and migration. | The c-Rel subunit of NF-κB is a crucial regulator of phenotype and motility of HaCaT keratinocytes.
Lorenz VN, Schön MP, Seitz CS. | 04/30/2016 |