| MARCH5-mediated downregulation of ACC2 promotes fatty acid oxidation and tumor progression in ovarian cancer. | MARCH5-mediated downregulation of ACC2 promotes fatty acid oxidation and tumor progression in ovarian cancer.
Zhao S, Wang Q, Zhang X, Ma B, Shi Y, Yin Y, Kong W, Zhang W, Li J, Yang H. | 02/1/2024 |
| Epstein-Barr virus induces germinal center light zone chromatin architecture and promotes survival through enhancer looping at the BCL2A1 locus. | Epstein-Barr virus induces germinal center light zone chromatin architecture and promotes survival through enhancer looping at the BCL2A1 locus.
Dai J, SoRelle ED, Heckenberg E, Song L, Cable JM, Crawford GE, Luftig MA., Free PMC Article | 01/29/2024 |
| BCL2A1 is associated with tumor-associated macrophages and unfavorable prognosis in human gliomas. | BCL2A1 is associated with tumor-associated macrophages and unfavorable prognosis in human gliomas.
Gao L, Ye Z, Peng S, Lei P, Song P, Li Z, Zhou L, Hua Q, Cheng L, Wei H, Liu J, Cai Q., Free PMC Article | 11/14/2023 |
| CARD11 gain of function upregulates BCL2A1 expression and promotes resistance to targeted therapies combination in B-cell lymphoma. | CARD11 gain of function upregulates BCL2A1 expression and promotes resistance to targeted therapies combination in B-cell lymphoma.
Decombis S, Bellanger C, Le Bris Y, Madiot C, Jardine J, Santos JC, Boulet D, Dousset C, Menard A, Kervoelen C, Douillard E, Moreau P, Minvielle S, Moreau-Aubry A, Tessoulin B, Roue G, Bidère N, Le Gouill S, Pellat-Deceunynck C, Chiron D. | 11/7/2023 |
| MiR-3976 regulates HCT-8 cell apoptosis and parasite burden by targeting BCL2A1 in response to Cryptosporidium parvum infection. | MiR-3976 regulates HCT-8 cell apoptosis and parasite burden by targeting BCL2A1 in response to Cryptosporidium parvum infection.
Li J, Sun L, Xie F, Shao T, Wu S, Li X, Zhang L, Wang R., Free PMC Article | 07/12/2023 |
| Bulk RNA Sequencing With Integrated Single-Cell RNA Sequencing Identifies BCL2A1 as a Potential Diagnostic and Prognostic Biomarker for Sepsis. | Bulk RNA Sequencing With Integrated Single-Cell RNA Sequencing Identifies BCL2A1 as a Potential Diagnostic and Prognostic Biomarker for Sepsis.
Li J, Zhou M, Feng JQ, Hong SM, Yang SY, Zhi LX, Lin WY, Zhu C, Yu YT, Lu LJ., Free PMC Article | 07/23/2022 |
| Construction of three-gene-based prognostic signature and analysis of immune cells infiltration in children and young adults with B-acute lymphoblastic leukemia. | Construction of three-gene-based prognostic signature and analysis of immune cells infiltration in children and young adults with B-acute lymphoblastic leukemia.
Xiang C, Wu J, Yu L., Free PMC Article | 07/23/2022 |
| lncRNA PANTR1 Upregulates BCL2A1 Expression to Promote Tumorigenesis and Warburg Effect of Hepatocellular Carcinoma through Restraining miR-587. | lncRNA PANTR1 Upregulates BCL2A1 Expression to Promote Tumorigenesis and Warburg Effect of Hepatocellular Carcinoma through Restraining miR-587.
Ma X, Mao Z, Zhu J, Liu H, Chen F., Free PMC Article | 01/15/2022 |
| LncRNA HORAS5 promotes taxane resistance in castration-resistant prostate cancer via a BCL2A1-dependent mechanism. | LncRNA HORAS5 promotes taxane resistance in castration-resistant prostate cancer via a BCL2A1-dependent mechanism.
Pucci P, Venalainen E, Alborelli I, Quagliata L, Hawkes C, Mather R, Romero I, Rigas SH, Wang Y, Crea F. | 09/11/2021 |
| Molecular stratification by BCL2A1 and AIM2 provides additional prognostic value in penile squamous cell carcinoma. | Molecular stratification by BCL2A1 and AIM2 provides additional prognostic value in penile squamous cell carcinoma.
Tan X, Chen D, Guo S, Wang Y, Zou Y, Wu Z, Zhou F, Qin Z, Liu Z, Cao Y, Lin C, Yuan G, Yao K., Free PMC Article | 07/24/2021 |
| Snail augments fatty acid oxidation by suppression of mitochondrial ACC2 during cancer progression. | Snail augments fatty acid oxidation by suppression of mitochondrial ACC2 during cancer progression.
Yang JH, Kim NH, Yun JS, Cho ES, Cha YH, Cho SB, Lee SH, Cha SY, Kim SY, Choi J, Nguyen TM, Park S, Kim HS, Yook JI., Free PMC Article | 07/10/2021 |
| Characterization of a novel human BFL-1-specific monoclonal antibody. | Characterization of a novel human BFL-1-specific monoclonal antibody.
Gangoda L, Teh CE, Dengler MA, Best SA, Weeden CE, Tai L, Lee EF, Fairlie WD, Sutherland KD, Harrison LC, Gray DH, Strasser A, Herold MJ., Free PMC Article | 07/3/2021 |
| A redox switch regulates the structure and function of anti-apoptotic BFL-1. | A redox switch regulates the structure and function of anti-apoptotic BFL-1.
Korshavn KJ, Wales TE, Bird GH, Engen JR, Walensky LD., Free PMC Article | 11/21/2020 |
| BFL1 inhibits apoptosis through three distinct mechanisms which are similar but not identical to those of BCLXL, the paradigmatic antiapoptotic BCL2 family protein. | BFL1 modulates apoptosis at the membrane level through a bifunctional and multimodal mechanism showing key differences with BCLXL.
Flores-Romero H, Landeta O, Ugarte-Uribe B, Cosentino K, García-Porras M, García-Sáez AJ, Basañez G., Free PMC Article | 07/25/2020 |
| prenylated Rab acceptor 1 (RABAC1 or PRA1) inhibits the anti-apoptotic activity of BCL2A1 and induces apoptosis in AGS gastric cancer cells. | Prenylated Rab acceptor RABAC1 inhibits anti-apoptotic protein BCL2A1 and induces apoptosis.
Kim JT, Cho HJ, Cho MY, Lim J, Park ES, Lim JS, Lee HG. | 07/11/2020 |
| overexpression of TRIM28 or knock-out of TRIM17 reduced BCLA1 protein levels and restored sensitivity of melanoma cells to BRAF-targeted therapy. Therefore, our data describe a molecular rheostat in which two proteins of the TRIM family antagonistically regulate BCL2A1 stability and modulate cell death. | TRIM17 and TRIM28 antagonistically regulate the ubiquitination and anti-apoptotic activity of BCL2A1.
Lionnard L, Duc P, Brennan MS, Kueh AJ, Pal M, Guardia F, Mojsa B, Damiano MA, Mora S, Lassot I, Ravichandran R, Cochet C, Aouacheria A, Potts PR, Herold MJ, Desagher S, Kucharczak J., Free PMC Article | 07/11/2020 |
| Comparative transcriptome analysisuncovered BCL2A1 as a potential mediator of ABT-199 resistance in acute myeloid leukemias | Genetic characterization of ABT-199 sensitivity in human AML.
Bisaillon R, Moison C, Thiollier C, Krosl J, Bordeleau ME, Lehnertz B, Lavallée VP, MacRae T, Mayotte N, Labelle C, Boucher G, Spinella JF, Boivin I, D'Angelo G, Lavallée S, Marinier A, Lemieux S, Hébert J, Sauvageau G. | 07/4/2020 |
| Molecular characterization of anti-apoptotic BFL1 and MCL1 enabled facile prediction and design of peptides that bind to them. | Tertiary Structural Motif Sequence Statistics Enable Facile Prediction and Design of Peptides that Bind Anti-apoptotic Bfl-1 and Mcl-1.
Frappier V, Jenson JM, Zhou J, Grigoryan G, Keating AE., Free PMC Article | 02/29/2020 |
| the results of present study indicated that overexpression of ACC1 is significantly associated with the survival time of patients with liver cancer, and may provide insight into the association between ACC1 and cell proliferation in BRL 3A cells. | ACC1 is overexpressed in liver cancers and contributes to the proliferation of human hepatoma Hep G2 cells and the rat liver cell line BRL 3A.
Ye B, Yin L, Wang Q, Xu C., Free PMC Article | 08/3/2019 |
| Crystal structures of anti-apoptotic BFL-1 and its complex with a covalent stapled BH3 peptide inhibitor have been presented. | Crystal Structures of Anti-apoptotic BFL-1 and Its Complex with a Covalent Stapled Peptide Inhibitor.
Harvey EP, Seo HS, Guerra RM, Bird GH, Dhe-Paganon S, Walensky LD., Free PMC Article | 12/1/2018 |
| Demonstrate immunohistochemical expression of Wnt11 and BCL2A1 in complete moles and normal villi. | Immunohistochemical Expression and Clinical Significance of Wnt11 and BCL2A1 in Complete Moles.
Hao Z, Lü W, Cheng X, Zhou C. | 08/13/2016 |
| Bfl-1 was mitochondrially resident in both resting and apoptotic cells and experienced regulation by the proteasome and NFkappaB pathways. | Role of the pro-survival molecule Bfl-1 in melanoma.
Hind CK, Carter MJ, Harris CL, Chan HT, James S, Cragg MS. | 09/26/2015 |
| Bcl2a1 overexpressing granulocytic MDSCs demonstrated prolonged survival. | IFN-γ regulates survival and function of tumor-induced CD11b+ Gr-1high myeloid derived suppressor cells by modulating the anti-apoptotic molecule Bcl2a1.
Medina-Echeverz J, Haile LA, Zhao F, Gamrekelashvili J, Ma C, Métais JY, Dunbar CE, Kapoor V, Manns MP, Korangy F, Greten TF., Free PMC Article | 11/22/2014 |
| Results indicate that mismatches in minor H antigens HA-8 (KIAA0020) and ACC-1 (BCL2A1) predisposed to chronic graft-versus-host disease (GvHD). | Minor histocompatibility antigens as determinants for graft-versus-host disease after allogeneic haematopoietic stem cell transplantation.
Turpeinen H, Ojala PJ, Ojala K, Miettinen M, Volin L, Partanen J. | 07/5/2014 |
| BCL2A1 is a novel marker associated with seizure prognosis following surgery for low-grade brain neoplasms. | BCL2A1 is a potential biomarker for postoperative seizure control in patients with low-grade gliomas.
You G, Feng L, Yan W, Zhang W, Wang YZ, Li SW, Li SW, Li GL, Song YJ, Kang CS, You YP, Jiang T., Free PMC Article | 05/31/2014 |