| Gene expression meta-analysis in patients with schizophrenia reveals up-regulation of RGS2 and RGS16 in Brodmann Area 10. | Gene expression meta-analysis in patients with schizophrenia reveals up-regulation of RGS2 and RGS16 in Brodmann Area 10.
Shriebman Y, Yitzhaky A, Kosloff M, Hertzberg L. | 02/16/2023 |
| RGS2 promotes estradiol biosynthesis by trophoblasts during human pregnancy. | RGS2 promotes estradiol biosynthesis by trophoblasts during human pregnancy.
Tang C, Jin M, Ma B, Cao B, Lin C, Xu S, Li J, Xu Q., Free PMC Article | 02/10/2023 |
| Fatty acid metabolism is related to the immune microenvironment changes of gastric cancer and RGS2 is a new tumor biomarker. | Fatty acid metabolism is related to the immune microenvironment changes of gastric cancer and RGS2 is a new tumor biomarker.
Yang S, Sun B, Li W, Yang H, Li N, Zhang X., Free PMC Article | 01/14/2023 |
| MicroRNA-494-3p facilitates the progression of bladder cancer by mediating the KLF9/RGS2 axis. | MicroRNA-494-3p facilitates the progression of bladder cancer by mediating the KLF9/RGS2 axis.
Xu XH, Sun JM, Chen XF, Zeng XY, Zhou HZ. | 11/12/2022 |
| Regulator of G protein signaling 2 is inhibited by hypoxia-inducible factor-1alpha/E1A binding protein P300 complex upon hypoxia in human preeclampsia. | Regulator of G protein signaling 2 is inhibited by hypoxia-inducible factor-1α/E1A binding protein P300 complex upon hypoxia in human preeclampsia.
Jin M, Xu S, Cao B, Xu Q, Yan Z, Ren Q, Lin C, Tang C. | 06/18/2022 |
| The Association of RGS2 and Slug in the Androgen-induced Acquisition of Mesenchymal Features of Breast MDA-MB-453 Cancer Cells. | The Association of RGS2 and Slug in the Androgen-induced Acquisition of Mesenchymal Features of Breast MDA-MB-453 Cancer Cells.
Alsafadi DB, Abdullah MS, Bawadi R, Ahram M. | 05/14/2022 |
| Morphological and biological properties of silica nanoparticles for CRTC3-siRNA delivery and downregulation of the RGS2 expression in preadipocytes. | Morphological and biological properties of silica nanoparticles for CRTC3-siRNA delivery and downregulation of the RGS2 expression in preadipocytes.
Mares-García AS, Ortiz Magdaleno M, Gordillo-Moscoso A, Cárdenas-Galindo MG, Ávila Hernández IN, Escobar-García DM, Márquez-Lucero A, Pozos-Guillén A. | 02/26/2022 |
| MicroRNA-3935 promotes human trophoblast cell epithelial-mesenchymal transition through tumor necrosis factor receptor-associated factor 6/regulator of G protein signaling 2 axis. | MicroRNA-3935 promotes human trophoblast cell epithelial-mesenchymal transition through tumor necrosis factor receptor-associated factor 6/regulator of G protein signaling 2 axis.
Jin M, Xu S, Li J, Yao Y, Tang C., Free PMC Article | 01/29/2022 |
| RGS2-mediated translational control mediates cancer cell dormancy and tumor relapse. | RGS2-mediated translational control mediates cancer cell dormancy and tumor relapse.
Cho J, Min HY, Lee HJ, Hyun SY, Sim JY, Noh M, Hwang SJ, Park SH, Boo HJ, Lee HJ, Hong S, Park RW, Shin YK, Hung MC, Lee HY., Free PMC Article | 09/11/2021 |
| Regulators of G-protein signaling, RGS2 and RGS4, inhibit protease-activated receptor 4-mediated signaling by forming a complex with the receptor and Galpha in live cells. | Regulators of G-protein signaling, RGS2 and RGS4, inhibit protease-activated receptor 4-mediated signaling by forming a complex with the receptor and Gα in live cells.
Kim Y, Ghil S., Free PMC Article | 08/14/2021 |
| Effect of the regulator of G-protein signaling 2 on the proliferation and invasion of oral squamous cell carcinoma cells and its molecular mechanism. | Effect of the regulator of G-protein signaling 2 on the proliferation and invasion of oral squamous cell carcinoma cells and its molecular mechanism.
Lin CZ, Liu ZQ, Zhou WK, Ji T, Cao W., Free PMC Article | 07/10/2021 |
| N-Terminal Targeting of Regulator of G Protein Signaling Protein 2 for F-Box Only Protein 44-Mediated Proteasomal Degradation. | N-Terminal Targeting of Regulator of G Protein Signaling Protein 2 for F-Box Only Protein 44-Mediated Proteasomal Degradation.
McNabb HJ, Gonzalez S, Muli CS, Sjögren B. | 12/12/2020 |
| RGS2 is prognostic for development of castration resistance and cancer-specific survival in castration-resistant prostate cancer. | RGS2 is prognostic for development of castration resistance and cancer-specific survival in castration-resistant prostate cancer.
Linder A, Larsson K, Welén K, Damber JE. | 09/12/2020 |
| Study found downregulated RGS2 expression in early low grade prostate cancer (PC) which was caused by hypoxia. Its knockdown induced epithelial features and impaired metastatic properties. High RGS2 levels in advanced PC were correlated to poor survival and a metastatic status. This study describes new roles for RGS2 during PC progression and prognostic potential discriminating the indolent from metastatic forms. | Analysis of regulator of G-protein signalling 2 (RGS2) expression and function during prostate cancer progression.
Linder A, Hagberg Thulin M, Damber JE, Welén K., Free PMC Article | 11/2/2019 |
| Low RGS2 expression due to DNA hypermethylation is associated with inflammation in cystic fibrosis. | DNA Methylation Regulates RGS2-induced S100A12 Expression in Airway Epithelial Cells.
Bouvet GF, Voisin G, Cyr Y, Bascunana V, Massé C, Berthiaume Y. | 07/13/2019 |
| Interplay between negative and positive design elements in Galpha helical domains of G proteins determines interaction specificity toward RGS2. | Interplay between negative and positive design elements in Gα helical domains of G proteins determines interaction specificity toward RGS2.
Kasom M, Gharra S, Sadiya I, Avital-Shacham M, Kosloff M. | 04/6/2019 |
| Due to the higher distribution of GG genotype and G allele in the vasopressor-response subgroup, RGS2 C1114G may be associated with the regulation of blood pressure during the onset of vasovagal syncope in children | [Association between C1114G polymorphism in the regulator of G protein signaling 2 and vasovagal syncope in children].
Chen TT, Huang YJ, Wang JY, Zhang GQ, Xu M, Huang M. | 04/6/2019 |
| RGS2 rs4606 alters the risk of developing a range of anxiety but also depressive disorders after childhood adversities; a complex risk pattern of genotype, environmental factors, and preexisting anxiety contributes to subsequent depression development. | Interplay between RGS2 and childhood adversities in predicting anxiety and depressive disorders: Findings from a general population sample.
Asselmann E, Hertel J, Schmidt CO, Homuth G, Nauck M, Beesdo-Baum K, Grabe HJ, Pané-Farré CA. | 03/2/2019 |
| Results showed no association between genotypes and preeclampsia for polymorphisms rs5186, rs4606 in 3'UTR of genes ACVR2A, AGTR1 and RGS2 in women with preeclampsia | Association between 3'UTR polymorphisms in genes ACVR2A, AGTR1 and RGS2 and preeclampsia.
Mendelova A, Holubekova V, Grendar M, Zubor P, Svecova I, Loderer D, Snahnicanova Z, Biringer K, Danko J, Lasabova Z. | 07/21/2018 |
| RGS2 is suggested as a novel AD biomarker (alongside other genes) toward early AD detection and future disease modifying therapeutics. | RGS2 expression predicts amyloid-β sensitivity, MCI and Alzheimer's disease: genome-wide transcriptomic profiling and bioinformatics data mining.
Hadar A, Milanesi E, Squassina A, Niola P, Chillotti C, Pasmanik-Chor M, Yaron O, Martásek P, Rehavi M, Weissglas-Volkov D, Shomron N, Gozes I, Gurwitz D., Free PMC Article | 12/9/2017 |
| Upregulated RGS2 contributes significantly to the anti-fibrotic effects of pirfenidone in idiopathic pulmonary fibrosis. | Upregulation of RGS2: a new mechanism for pirfenidone amelioration of pulmonary fibrosis.
Xie Y, Jiang H, Zhang Q, Mehrotra S, Abel PW, Toews ML, Wolff DW, Rennard S, Panettieri RA Jr, Casale TB, Tu Y., Free PMC Article | 12/2/2017 |
| study provides functional data for 16 human RGS2 missense variants on their effects on AT1R-mediated calcium mobilization and provides molecular understanding of those variants with functional loss in vitro. | Human Missense Mutations in Regulator of G Protein Signaling 2 Affect the Protein Function Through Multiple Mechanisms.
Phan HTN, Sjögren B, Neubig RR. | 11/4/2017 |
| Our results suggest that RGS2 might be involved in the pathogenesis of preeclampsia particularly in overweight women and contribute to their increased risk for hypertension and other types of cardiovascular disease later in life. | An RGS2 3'UTR polymorphism is associated with preeclampsia in overweight women.
Karppanen T, Kaartokallio T, Klemetti MM, Heinonen S, Kajantie E, Kere J, Kivinen K, Pouta A, Staff AC, Laivuori H., Free PMC Article | 09/30/2017 |
| Data suggest that epigenetic changes in histone acetylation and DNA methylation may contribute to the repression of RGS2 (regulator of G-protein signaling 2) expression in chemo-resistant ovarian cancer cells; regulation of HDAC1 (histone deacetylase 1) and DNMT1 (DNA methyltransferase 1) contribute to the suppression of RGS2. | Epigenetic regulation of RGS2 (Regulator of G-protein signaling 2) in chemoresistant ovarian cancer cells.
Cacan E. | 07/29/2017 |
| The RGS2 (-391, C>G) genetic polymorphism may serve as a biomarker to predict a patient's response to antihypertensive drug therapy | The RGS2 (-391, C>G) genetic variation correlates to antihypertensive drug responses in Chinese patients with essential hypertension.
He F, Luo J, Zhang Z, Luo Z, Fan L, He Y, Wen J, Zhu D, Gao J, Wang Y, Qian Y, Zhou H, Chen X, Zhang W., Free PMC Article | 04/2/2016 |