| Epigenetic insights into Familial Mediterranean Fever: Increased RGS10 expression and histone modifications accompanies inflammation in familial Mediterranean fever disease. | Epigenetic insights into Familial Mediterranean Fever: Increased RGS10 expression and histone modifications accompanies inflammation in familial Mediterranean fever disease.
Caldiran F, Deveci K, Cacan E. | 03/5/2024 |
| RGS10 suppression by DNA methylation is associated with low survival rates in colorectal carcinoma. | RGS10 suppression by DNA methylation is associated with low survival rates in colorectal carcinoma.
Caldiran FY, Cacan E. | 08/13/2022 |
| Experimental colitis promotes sustained, sex-dependent, T-cell-associated neuroinflammation and parkinsonian neuropathology. | Experimental colitis promotes sustained, sex-dependent, T-cell-associated neuroinflammation and parkinsonian neuropathology.
Houser MC, Caudle WM, Chang J, Kannarkat GT, Yang Y, Kelly SD, Oliver D, Joers V, Shannon KM, Keshavarzian A, Tansey MG., Free PMC Article | 01/29/2022 |
| Short stature and combined immunodeficiency associated with mutations in RGS10. | Short stature and combined immunodeficiency associated with mutations in RGS10.
Chinn IK, Xie Z, Chan EC, Nagata BM, Koval A, Chen WS, Zhang F, Ganesan S, Hong DN, Suzuki M, Nardone G, Moore IN, Katanaev VL, Balazs AE, Liu C, Lupski JR, Orange JS, Druey KM., Free PMC Article | 01/22/2022 |
| Regulator of G protein signaling 10: Structure, expression and functions in cellular physiology and diseases. | Regulator of G protein signaling 10: Structure, expression and functions in cellular physiology and diseases.
Almutairi F, Lee JK, Rada B., Free PMC Article | 10/23/2021 |
| A broad analysis in clinical and in vitro models on regulator of G-protein signalling 10 regulation that is associated with ovarian cancer progression and chemoresistance. | A broad analysis in clinical and in vitro models on regulator of G-protein signalling 10 regulation that is associated with ovarian cancer progression and chemoresistance.
Kucuk B, Kibar B, Cacan E. | 07/10/2021 |
| RGS10 inhibits COX-2 expression. | RGS10 Regulates the Expression of Cyclooxygenase-2 and Tumor Necrosis Factor Alpha through a G Protein-Independent Mechanism.
Alqinyah M, Almutairi F, Wendimu MY, Hooks SB., Free PMC Article | 04/20/2019 |
| RGS10 plays a role in chemoresistance in ovarian cancer. Loss of RGS10 enhances survival among these cells. | Cellular deficiency in the RGS10 protein facilitates chemoresistant ovarian cancer.
Hooks SB, Murph MM., Free PMC Article | 06/11/2016 |
| RGS10 could serve in a novel, and previously unknown, role by accelerating the hydrolysis of GTP from Rheb in ovarian cancer cells. | Suppression of the GTPase-activating protein RGS10 increases Rheb-GTP and mTOR signaling in ovarian cancer cells.
Altman MK, Alshamrani AA, Jia W, Nguyen HT, Fambrough JM, Tran SK, Patel MB, Hoseinzadeh P, Beedle AM, Murph MM., Free PMC Article | 02/6/2016 |
| Inhibition of HDAC1 and DNMT1 modulate RGS10 expression and decrease ovarian cancer chemoresistance. | Inhibition of HDAC1 and DNMT1 modulate RGS10 expression and decrease ovarian cancer chemoresistance.
Cacan E, Ali MW, Boyd NH, Hooks SB, Greer SF., Free PMC Article | 10/4/2014 |
| The results suggest unaltered membrane RGS4 and cytosolic RGS10 proteins levels in schizophrenia and major depression. | Brain RGS4 and RGS10 protein expression in schizophrenia and depression. Effect of drug treatment.
Rivero G, Gabilondo AM, García-Sevilla JA, Callado LF, La Harpe R, Morentin B, Meana JJ. | 08/3/2013 |
| Data show that that SPL/RGS/SHP1 complexes are present in resting platelets where constitutive phosphorylation of SPL(Y398) creates an atypical binding site for SHP-1. | A newly identified complex of spinophilin and the tyrosine phosphatase, SHP-1, modulates platelet activation by regulating G protein-dependent signaling.
Ma P, Cierniewska A, Signarvic R, Cieslak M, Kong H, Sinnamon AJ, Neubig RR, Newman DK, Stalker TJ, Brass LF., Free PMC Article | 05/26/2012 |
| RGS10 is a key molecule that contributes to the inhibition of Galpha-dependent signaling during chemokine-activated alpha4beta1- and alphaLbeta2-dependent T cell adhesion. | RGS10 restricts upregulation by chemokines of T cell adhesion mediated by α4β1 and αLβ2 integrins.
García-Bernal D, Dios-Esponera A, Sotillo-Mallo E, García-Verdugo R, Arellano-Sánchez N, Teixidó J. | 10/29/2011 |
| RGS10 and RGS4 proteins are both detected in postmortem prefrontal cortex. | Characterization of regulators of G-protein signaling RGS4 and RGS10 proteins in the postmortem human brain.
Rivero G, Gabilondo AM, García-Sevilla JA, La Harpe R, Morentín B, Javier Meana J. | 09/10/2011 |
| Results establish RGS10 and RGS17 as novel regulators of cell survival and chemoresistance in ovarian cancer cells and suggest that their reduced expression may be diagnostic of chemoresistance. | Regulators of G-Protein signaling RGS10 and RGS17 regulate chemoresistance in ovarian cancer cells.
Hooks SB, Callihan P, Altman MK, Hurst JH, Ali MW, Murph MM., Free PMC Article | 01/22/2011 |
| Results demonstrate the specificity of RGS10A as a key component in the RANKL-evoked signaling pathway for osteoclast differentiation. | Specificity of RGS10A as a key component in the RANKL signaling mechanism for osteoclast differentiation.
Yang S, Chen W, Stashenko P, Li YP., Free PMC Article | 01/21/2010 |
| Observational study of gene-disease association. (HuGE Navigator) | See all PubMed (4) articlesGenetic variations in regulator of G-protein signaling genes as susceptibility loci for second primary tumor/recurrence in head and neck squamous cell carcinoma.
Wang J, Lippman SM, Lee JJ, Yang H, Khuri FR, Kim E, Lin J, Chang DW, Lotan R, Hong WK, Wu X. Association study of 182 candidate genes in anorexia nervosa.
Pinheiro AP, Bulik CM, Thornton LM, Sullivan PF, Root TL, Bloss CS, Berrettini WH, Schork NJ, Kaye WH, Bergen AW, Magistretti P, Brandt H, Crawford S, Crow S, Fichter MM, Goldman D, Halmi KA, Johnson C, Kaplan AS, Keel PK, Klump KL, La Via M, Mitchell JE, Strober M, Rotondo A, Treasure J, Woodside DB. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.
Grupe A, Li Y, Rowland C, Nowotny P, Hinrichs AL, Smemo S, Kauwe JS, Maxwell TJ, Cherny S, Doil L, Tacey K, van Luchene R, Myers A, Wavrant-De Vrièze F, Kaleem M, Hollingworth P, Jehu L, Foy C, Archer N, Hamilton G, Holmans P, Morris CM, Catanese J, Sninsky J, White TJ, Powell J, Hardy J, O'Donovan M, Lovestone S, Jones L, Morris JC, Thal L, Owen M, Williams J, Goate A. Novel missense polymorphism in the regulator of G-protein signaling 10 gene: analysis of association with schizophrenia.
Hishimoto A, Shirakawa O, Nishiguchi N, Aoyama S, Ono H, Hashimoto T, Maeda K. | 03/13/2008 |
| diffraction data were collected to 2.5 A resolution at 100 K using synchrotron radiation at Pohang beamline 4A | Crystallization and preliminary X-ray crystallographic analysis of human RGS10 complexed with Galphai3.
Lee HK, Rhee KH, Kim CW, Hwang KY, Kim EE., Free PMC Article | 01/21/2010 |