| Downregulation of Mirlet7 miRNA family promotes Tc17 differentiation and emphysema via de-repression of RORgammat. | Downregulation of Mirlet7 miRNA family promotes Tc17 differentiation and emphysema via de-repression of RORγt.
Erice PA, Huang X, Seasock MJ, Robertson MJ, Tung HY, Perez-Negron MA, Lotlikar SL, Corry DB, Kheradmand F, Rodriguez A., Free PMC Article | 06/7/2024 |
| Th17 cell master transcription factor RORC2 regulates HIV-1 gene expression and viral outgrowth. | Th17 cell master transcription factor RORC2 regulates HIV-1 gene expression and viral outgrowth.
Wiche Salinas TR, Zhang Y, Sarnello D, Zhyvoloup A, Marchand LR, Fert A, Planas D, Lodha M, Chatterjee D, Karwacz K, Oxenford S, Routy JP, Irlbeck D, Amrine-Madsen H, Ancuta P, Fassati A., Free PMC Article | 01/15/2022 |
| Conformational Changes of RORgamma During Response Element Recognition and Coregulator Engagement. | Conformational Changes of RORγ During Response Element Recognition and Coregulator Engagement.
Strutzenberg TS, Zhu Y, Novick SJ, Garcia-Ordonez RD, Doebelin C, He Y, Chang MR, Kamenecka TM, Edwards DP, Griffin PR., Free PMC Article | 12/4/2021 |
| Transcriptomic effects of rs4845604, an IBD and allergy-associated RORC variant, in stimulated ex vivo CD4+ T cells. | Transcriptomic effects of rs4845604, an IBD and allergy-associated RORC variant, in stimulated ex vivo CD4+ T cells.
Wilson PA, Santos Franco S, He L, Galwey NW, Meakin J, McIntyre R, McHugh SM, Nolan MA, Spain SL, Carlson T, Lobera M, Rubio JP, Davis B, McCarthy LC., Free PMC Article | 11/27/2021 |
| RORC gene polymorphism is associated with acute kidney injury following cardiac surgery. | RORC gene polymorphism is associated with acute kidney injury following cardiac surgery.
Gholamipoor Z, Rahimzadeh M, Montazerghaem H, Naderi N. | 11/22/2021 |
| RORC overexpression as a sign of Th17 lymphocytes accumulation in multiple myeloma bone marrow. | RORC overexpression as a sign of Th17 lymphocytes accumulation in multiple myeloma bone marrow.
Ben Hmid A, Selmi O, Rekik R, Lamari H, Zamali I, Ladeb S, Safra I, Ben Othman T, Ben Romdhane N, Ben Ahmed M. | 11/22/2021 |
| Inherited PD-1 deficiency underlies tuberculosis and autoimmunity in a child. | Inherited PD-1 deficiency underlies tuberculosis and autoimmunity in a child.
Ogishi M, Yang R, Aytekin C, Langlais D, Bourgey M, Khan T, Ali FA, Rahman M, Delmonte OM, Chrabieh M, Zhang P, Gruber C, Pelham SJ, Spaan AN, Rosain J, Lei WT, Drutman S, Hellmann MD, Callahan MK, Adamow M, Wong P, Wolchok JD, Rao G, Ma CS, Nakajima Y, Yaguchi T, Chamoto K, Williams SC, Emile JF, Rozenberg F, Glickman MS, Rapaport F, Kerner G, Allington G, Tezcan I, Cagdas D, Hosnut FO, Dogu F, Ikinciogullari A, Rao VK, Kainulainen L, Béziat V, Bustamante J, Vilarinho S, Lifton RP, Boisson B, Abel L, Bogunovic D, Marr N, Notarangelo LD, Tangye SG, Honjo T, Gros P, Boisson-Dupuis S, Casanova JL., Free PMC Article | 10/9/2021 |
| Associations of TNFA, IL17A, and RORC mRNA expression levels in peripheral blood leukocytes with obesity-related asthma in adolescents. | Associations of TNFA, IL17A, and RORC mRNA expression levels in peripheral blood leukocytes with obesity-related asthma in adolescents.
Leija-Martínez JJ, Del-Río-Navarro BE, Sanchéz-Muñoz F, Muñoz-Hernández O, Hong E, Giacoman-Martínez A, Romero-Nava R, Patricio-Román KL, Hall-Mondragon MS, Espinosa-Velazquez D, Villafaña S, Huang F. | 09/18/2021 |
| Possible Role of the RORC Gene in Primary and Secondary Lymphedema: Review of the Literature and Genetic Study of Two Rare Causative Variants. | Possible Role of the RORC Gene in Primary and Secondary Lymphedema: Review of the Literature and Genetic Study of Two Rare Causative Variants.
Michelini S, Ricci M, Serrani R, Stuppia L, Beccari T, Veselenyiova D, Kenanoglu S, Barati S, Kurti D, Baglivo M, Basha SH, Krajcovic J, Dundar M, Bertelli M. | 09/18/2021 |
| Orphan nuclear receptor RORgamma confers doxorubicin resistance in prostate cancer. | Orphan nuclear receptor RORγ confers doxorubicin resistance in prostate cancer.
Gao M, Guo L, Wang H, Huang J, Han F, Xiang S, Wang J. | 08/14/2021 |
| Correlations of Helicobacter pylori with liver function, inflammatory factors and serum levels of FoxP3 and RORgammat in patients with hepatitis B cirrhosis. | Correlations of Helicobacter pylori with liver function, inflammatory factors and serum levels of FoxP3 and RORγt in patients with hepatitis B cirrhosis.
Zhao B, Sheng QJ, Qin Y, Wang XL, Zhao H, Zhao N. | 07/3/2021 |
| Cooperativity between the orthosteric and allosteric ligand binding sites of RORgammat. | Cooperativity between the orthosteric and allosteric ligand binding sites of RORγt.
de Vries RMJM, Meijer FA, Doveston RG, Leijten-van de Gevel IA, Brunsveld L., Free PMC Article | 06/26/2021 |
| Increased Expression of IL-17A and IL-17F Is Correlated With RUNX1 and RORgammaT in Pediatric Patients With Primary Immune Thrombocytopenia. | Increased Expression of IL-17A and IL-17F Is Correlated With RUNX1 and RORγT in Pediatric Patients With Primary Immune Thrombocytopenia.
Elnaenaey WA, Omar OM, Aboelwafa RA. | 05/22/2021 |
| Lower T Regulatory and Th17 Cell Populations Predicted by RT-PCR-Amplified FOXP3 and RORgammat Genes Are Not Rare in Patients With Primary Immunodeficiency Diseases. | Lower T Regulatory and Th17 Cell Populations Predicted by RT-PCR-Amplified FOXP3 and RORγt Genes Are Not Rare in Patients With Primary Immunodeficiency Diseases.
Lee WI, Huang JL, Lin SJ, Yeh KW, Chen LC, Ou LS, Yao TC, Jaing TH, Shih YF, Wu CY., Free PMC Article | 04/13/2021 |
| RORgamma Structural Plasticity and Druggability. | RORγ Structural Plasticity and Druggability.
Huang M, Bolin S, Miller H, Ng HL., Free PMC Article | 02/20/2021 |
| Ahr-Foxp3-RORgammat axis controls gut homing of CD4(+) T cells by regulating GPR15. | Ahr-Foxp3-RORγt axis controls gut homing of CD4(+) T cells by regulating GPR15.
Xiong L, Dean JW, Fu Z, Oliff KN, Bostick JW, Ye J, Chen ZE, Mühlbauer M, Zhou L., Free PMC Article | 02/13/2021 |
| The expression analyses of RMRP, DDX5, and RORC in RRMS patients treated with different drugs versus naive patients and healthy controls. | The expression analyses of RMRP, DDX5, and RORC in RRMS patients treated with different drugs versus naïve patients and healthy controls.
Rahmani S, Noorolyai S, Ayromlou H, Khaze Shahgoli V, Shanehbandi D, Baghbani E, Abdoli Shadbad M, Jigari-Asl F, Khamiriyan M, Safaralizadeh R, Baradaran B. | 02/2/2021 |
| Decipher manifestations and Treg /Th17 imbalance in multi-staging rheumatoid arthritis and correlation with TSDR/RORC methylation. | Decipher manifestations and Treg /Th17 imbalance in multi-staging rheumatoid arthritis and correlation with TSDR/RORC methylation.
Huang Y, Wang H, Ba X, Chen Z, Wang Y, Qin K, Huang Y, Shen P, Tu S. | 12/5/2020 |
| Decreased methylation profiles in the TNFA gene promoters in type 1 macrophages and in the IL17A and RORC gene promoters in Th17 lymphocytes have a causal association with non-atopic asthma caused by obesity: A hypothesis. | Decreased methylation profiles in the TNFA gene promoters in type 1 macrophages and in the IL17A and RORC gene promoters in Th17 lymphocytes have a causal association with non-atopic asthma caused by obesity: A hypothesis.
Leija-Martínez JJ, Huang F, Del-Río-Navarro BE, Sanchéz-Muñoz F, Romero-Nava R, Muñoz-Hernandez O, Rodríguez-Cortés O, Hall-Mondragon MS. | 11/28/2020 |
| Vitamin D receptors (VDR), hydroxylases CYP27B1 and CYP24A1 and retinoid-related orphan receptors (ROR) level in human uveal tract and ocular melanoma with different melanization levels. | Vitamin D receptors (VDR), hydroxylases CYP27B1 and CYP24A1 and retinoid-related orphan receptors (ROR) level in human uveal tract and ocular melanoma with different melanization levels.
Markiewicz A, Brożyna AA, Podgórska E, Elas M, Urbańska K, Jetten AM, Slominski AT, Jóźwicki W, Orłowska-Heitzman J, Dyduch G, Romanowska-Dixon B., Free PMC Article | 10/24/2020 |
| On the relationship between VDR, RORalpha and RORgamma receptors expression and HIF1-alpha levels in human melanomas. | On the relationship between VDR, RORα and RORγ receptors expression and HIF1-α levels in human melanomas.
Brożyna AA, Jóźwicki W, Jetten AM, Slominski AT., Free PMC Article | 10/24/2020 |
| Effects of guluronic acid, as a new NSAID with immunomodulatory properties on IL-17, RORgammat, IL-4 and GATA-3 gene expression in rheumatoid arthritis patients. | Effects of guluronic acid, as a new NSAID with immunomodulatory properties on IL-17, RORγt, IL-4 and GATA-3 gene expression in rheumatoid arthritis patients.
Khadem Azarian S, Jafarnezhad-Ansariha F, Nazeri S, Azizi G, Aghazadeh Z, Hosseinzadeh E, Mirshafiey A. | 10/10/2020 |
| A significant over-expression of RORgammaT was observed in peripheral blood from relapsing-remitting multiple sclerosis patients. | RORγT is overexpressed in iNKT and γδ T cells during relapse in relapsing-remitting multiple sclerosis.
Zarobkiewicz MK, Kowalska W, Halczuk P, Woś J, Jodłowska-Jędrych B, Rejdak K, Roliński J, Bojarska-Junak AA. | 06/20/2020 |
| These results suggest that RORgamma was an important regulator in hepatocellular carcinoma (HCC), and our finding provides new insights into the significance of RORgamma in HCC. | Hepatitis B Virus X Protein-Induced RORγ Expression to Promote the Migration and Proliferation of Hepatocellular Carcinoma.
Huang Y, Liang H, He C, Peng F., Free PMC Article | 05/2/2020 |
| the structural determinants of RORgamma activation, were investigated. | HDX-MS reveals structural determinants for RORγ hyperactivation by synthetic agonists.
Strutzenberg TS, Garcia-Ordonez RD, Novick SJ, Park H, Chang MR, Doebellin C, He Y, Patouret R, Kamenecka TM, Griffin PR., Free PMC Article | 02/22/2020 |