| BAIAP2L1 accelerates breast cancer progression and chemoresistance by activating AKT signaling through binding with ribosomal protein L3. | BAIAP2L1 accelerates breast cancer progression and chemoresistance by activating AKT signaling through binding with ribosomal protein L3.
Deng N, Zhang X, Zhang Y., Free PMC Article | 03/13/2023 |
| Suppression of RPL34 Inhibits Tumor Cell Proliferation and Promotes Apoptosis in Glioblastoma. | Suppression of RPL34 Inhibits Tumor Cell Proliferation and Promotes Apoptosis in Glioblastoma.
Du C, Wang T, Jia J, Li J, Xiao Y, Wang J, Mao P, Wang N, Shi L, Wang M. | 07/16/2022 |
| METTL18-mediated histidine methylation of RPL3 modulates translation elongation for proteostasis maintenance. | METTL18-mediated histidine methylation of RPL3 modulates translation elongation for proteostasis maintenance.
Matsuura-Suzuki E, Shimazu T, Takahashi M, Kotoshiba K, Suzuki T, Kashiwagi K, Sohtome Y, Akakabe M, Sodeoka M, Dohmae N, Ito T, Shinkai Y, Iwasaki S., Free PMC Article | 06/18/2022 |
| S-Adenosyl-l-Methionine Overcomes uL3-Mediated Drug Resistance in p53 Deleted Colon Cancer Cells. | S-Adenosyl-l-Methionine Overcomes uL3-Mediated Drug Resistance in p53 Deleted Colon Cancer Cells.
Mosca L, Pagano M, Pecoraro A, Borzacchiello L, Mele L, Cacciapuoti G, Porcelli M, Russo G, Russo A., Free PMC Article | 09/11/2021 |
| DUOX2 promotes the progression of colorectal cancer cells by regulating the AKT pathway and interacting with RPL3. | DUOX2 promotes the progression of colorectal cancer cells by regulating the AKT pathway and interacting with RPL3.
Zhang X, Han J, Feng L, Zhi L, Jiang D, Yu B, Zhang Z, Gao B, Zhang C, Li M, Zhao L, Wang G., Free PMC Article | 06/26/2021 |
| Human METTL18 is a histidine-specific methyltransferase that targets RPL3 and affects ribosome biogenesis and function. | Human METTL18 is a histidine-specific methyltransferase that targets RPL3 and affects ribosome biogenesis and function.
Małecki JM, Odonohue MF, Kim Y, Jakobsson ME, Gessa L, Pinto R, Wu J, Davydova E, Moen A, Olsen JV, Thiede B, Gleizes PE, Leidel SA, Falnes PØ., Free PMC Article | 05/15/2021 |
| uL3 Mediated Nucleolar Stress Pathway as a New Mechanism of Action of Antiproliferative G-quadruplex TBA Derivatives in Colon Cancer Cells. | uL3 Mediated Nucleolar Stress Pathway as a New Mechanism of Action of Antiproliferative G-quadruplex TBA Derivatives in Colon Cancer Cells.
Pecoraro A, Virgilio A, Esposito V, Galeone A, Russo G, Russo A., Free PMC Article | 04/13/2021 |
| Ribosomal protein uL3 targets E2F1 and Cyclin D1 in cancer cell response to nucleolar stress. | Ribosomal protein uL3 targets E2F1 and Cyclin D1 in cancer cell response to nucleolar stress.
Pecoraro A, Carotenuto P, Russo G, Russo A., Free PMC Article | 10/31/2020 |
| The sensitivity of p53 null colon cancer cells to 5-FU can be enhanced using proapoptotic rpL3 gene. | Enhancement of 5-FU sensitivity by the proapoptotic rpL3 gene in p53 null colon cancer cells through combined polymer nanoparticles.
Russo A, Maiolino S, Pagliara V, Ungaro F, Tatangelo F, Leone A, Scalia G, Budillon A, Quaglia F, Russo G., Free PMC Article | 02/24/2018 |
| nucleolar stress induced by 5-fluorouracil in colon cancer cells devoid of p53 leads to the activation of ribosomal protein L3 as proapoptotic factor | 5-FU targets rpL3 to induce mitochondrial apoptosis via cystathionine-β-synthase in colon cancer cells lacking p53.
Pagliara V, Saide A, Mitidieri E, d'Emmanuele di Villa Bianca R, Sorrentino R, Russo G, Russo A., Free PMC Article | 02/24/2018 |
| We found that uL3 down-regulation correlates positively with multidrug resistance. Restoration of the uL3 protein level re-sensitized the resistant cells to the drug by regulating the reactive oxygen species (ROS) levels, glutathione content, glutamate release, and cystine uptake. | Role of uL3 in Multidrug Resistance in p53-Mutated Lung Cancer Cells.
Russo A, Saide A, Smaldone S, Faraonio R, Russo G., Free PMC Article | 04/22/2017 |
| rpL3 participates in the cell response to chemotherapy acting as a critical regulator of cell cycle, apoptosis and DNA repair, by modulating p21 expression | Human rpL3 plays a crucial role in cell response to nucleolar stress induced by 5-FU and L-OHP.
Esposito D, Crescenzi E, Sagar V, Loreni F, Russo A, Russo G., Free PMC Article | 09/26/2015 |
| The rpL3 is able to modulate the protein amounts of p21 through a novel pathway independent from p53 involving Sp1 and NPM. | Human rpL3 induces G₁/S arrest or apoptosis by modulating p21 (waf1/cip1) levels in a p53-independent manner.
Russo A, Esposito D, Catillo M, Pietropaolo C, Crescenzi E, Russo G., Free PMC Article | 08/10/2013 |
| NPM and KHSRP are two newly identified proteins involved in the regulation of rpL3 gene expression via alternative pre-mRNA splicing. | Autoregulatory circuit of human rpL3 expression requires hnRNP H1, NPM and KHSRP.
Russo A, Catillo M, Esposito D, Briata P, Pietropaolo C, Russo G., Free PMC Article | 12/10/2011 |
| working model in which rpL3 recruits hnRNP H1 and, through cooperation with other splicing factors, promotes selection of the alternative splice site | hnRNP H1 and intronic G runs in the splicing control of the human rpL3 gene.
Russo A, Siciliano G, Catillo M, Giangrande C, Amoresano A, Pucci P, Pietropaolo C, Russo G. | 06/28/2010 |
| Involved in progression and regulation of telomerase | Genes associated with telomerase activity levels in esophageal carcinoma cell lines.
Bergqvist M, Brattström D, Brodin D, Lindkvist A, Dahlman-Wright K, Dreilich M, Wagenius G, Paulsson-Karlsson Y. | 01/21/2010 |