| Characterizing ligand-receptor interactions and unveiling the pro-tumorigenic role of CCL16-CCR1 axis in the microenvironment of hepatocellular carcinoma. | Characterizing ligand-receptor interactions and unveiling the pro-tumorigenic role of CCL16-CCR1 axis in the microenvironment of hepatocellular carcinoma.
Dai Z, Wang Y, Sun N, Zhang C., Free PMC Article | 02/7/2024 |
| Structure and Dynamics of Human Chemokine CCL16-Implications for Biological Activity. | Structure and Dynamics of Human Chemokine CCL16-Implications for Biological Activity.
Weiergräber OH, Petrović D, Kislat A, Pattky M, Fabig J, Batra-Safferling R, Schulte Am Esch J, Hänel K, Huhn C, Strodel B, Homey B, Willbold D., Free PMC Article | 11/19/2022 |
| CC motif chemokine ligand 16 inhibits the progression of liver cirrhosis via inactivating hepatic stellate cells. | CC motif chemokine ligand 16 inhibits the progression of liver cirrhosis via inactivating hepatic stellate cells.
Zhuo JY, Lu D, Lin ZY, Cen BN, Wei XY, Xie HY, Zheng SS, Xu X. | 08/28/2021 |
| CCL16 maintains stem cell-like properties in breast cancer by activating CCR2/GSK3beta/beta-catenin/OCT4 axis. | CCL16 maintains stem cell-like properties in breast cancer by activating CCR2/GSK3β/β-catenin/OCT4 axis.
Shen W, Zhang X, Tang J, Zhang Z, Du R, Luo D, Liu X, Xia Y, Li Y, Wang S, Yan S, Yang W, Xiang R, Luo N, Luo Y, Li J., Free PMC Article | 08/21/2021 |
| Single nucleotide polymorphism (SNPs) located in and around the C-C motif chemokine ligand 16 (CCL16) gene are associated with CCL16 protein levels in blood plasma, and rs80329614 is the SNP most strongly associated with CCL16 protein levels in plasma. | Variants in CCL16 are associated with blood plasma and cerebrospinal fluid CCL16 protein levels.
Ebbert MT, Staley LA, Parker J, Parker S, Bailey M, Alzheimer’s Disease Neuroimaging Initiative, Ridge PG, Goate AM, Kauwe JS., Free PMC Article | 08/5/2017 |
| High umbilical artery CCL16 is prominently detected in preterm preeclamptic pregnancies with severe growth restriction. | Umbilical artery chemokine CCL16 is associated with preterm preeclampsia and fetal growth restriction.
Mäkikallio K, Kaukola T, Tuimala J, F Kingsmore S, Hallman M, Ojaniemi M. | 02/23/2013 |
| Data show that CCL-16 gene expression was upregulated by 7.46-fold in IBS patients when compared with controls and suggest a subclinical inflammatory component underlying IBS. | Pro-inflammatory chemokine C-C motif ligand 16 (CCL-16) dysregulation in irritable bowel syndrome (IBS): a pilot study.
Del Valle-Pinero AY, Martino AC, Taylor TJ, Majors BL, Patel NS, Heitkemper MM, Henderson WA., Free PMC Article | 04/21/2012 |
| Low umbilical cord blood chemokine CCL16 associates with spontaneous preterm birth | Cord blood chemokines differentiate between spontaneous and elective preterm births in singleton pregnancies.
Kaukola T, Ojaniemi M, Tuimala J, Herva R, Saarela T, Kingsmore SF, Hallman M. | 06/25/2011 |
| Elevated concentrations in bronchoalveolar lavage fluid from patients with eosinophilic pneumonia | Elevated concentrations of liver-expressed chemokine/CC chemokine ligand 16 in bronchoalveolar lavage fluid from patients with eosinophilic pneumonia.
Nureki S, Miyazaki E, Usagawa Y, Ueno T, Ando M, Takenaka R, Ito T, Ishii T, Kumamoto T. | 01/21/2010 |
| Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator) | Genetic susceptibility to respiratory syncytial virus bronchiolitis in preterm children is associated with airway remodeling genes and innate immune genes.
Siezen CL, Bont L, Hodemaekers HM, Ermers MJ, Doornbos G, Van't Slot R, Wijmenga C, Houwelingen HC, Kimpen JL, Kimman TG, Hoebee B, Janssen R. | 03/25/2009 |
| Observational study of gene-disease association. (HuGE Navigator) | See all PubMed (4) articlesInterleukin-9 polymorphism in infants with respiratory syncytial virus infection: an opposite effect in boys and girls.
Schuurhof A, Bont L, Siezen CL, Hodemaekers H, van Houwelingen HC, Kimman TG, Hoebee B, Kimpen JL, Janssen R. New genetic associations detected in a host response study to hepatitis B vaccine.
Davila S, Froeling FE, Tan A, Bonnard C, Boland GJ, Snippe H, Hibberd ML, Seielstad M. Genetic susceptibility to respiratory syncytial virus bronchiolitis is predominantly associated with innate immune genes.
Janssen R, Bont L, Siezen CL, Hodemaekers HM, Ermers MJ, Doornbos G, van 't Slot R, Wijmenga C, Goeman JJ, Kimpen JL, van Houwelingen HC, Kimman TG, Hoebee B. Genome-wide scan for visceral leishmaniasis susceptibility genes in Brazil.
Jamieson SE, Miller EN, Peacock CS, Fakiola M, Wilson ME, Bales-Holst A, Shaw MA, Silveira F, Shaw JJ, Jeronimo SM, Blackwell JM. | 03/13/2008 |
| CC chemokine-4 (HCC-4)/CCL16 transduces signals differently from other CCR1-dependent chemokines and may play different roles in the immune response. | Differential CCR1-mediated chemotaxis signaling induced by human CC chemokine HCC-4/CCL16 in HOS cells.
Kim IS, Jang SW, Sung HJ, Lee JS, Ko J. | 01/21/2010 |
| An adenoviral vector encoding human CCL16 injected into mice with pre-established mammary carcinoma induces strong antitumor response; when given before surgical excision of primary lesions, the treatment prevents metastatic spread and cures 63% of mice. | Intralesional injection of adenovirus encoding CC chemokine ligand 16 inhibits mammary tumor growth and prevents metastatic-induced death after surgical removal of the treated primary tumor.
Guiducci C, Di Carlo E, Parenza M, Hitt M, Giovarelli M, Musiani P, Colombo MP. | 01/21/2010 |
| Recombinant CCL16 significantly enhances the effector and the antigen-presenting function of macrophages and augments T cell lytic activity. | CCL16/LEC powerfully triggers effector and antigen-presenting functions of macrophages and enhances T cell cytotoxicity.
Cappello P, Caorsi C, Bosticardo M, De Angelis S, Novelli F, Forni G, Giovarelli M. | 01/21/2010 |
| CCL16 induced efficient migratory responses in human and mouse eosinophils. CCL16 is a novel functional ligand for H4 and may have a role in trafficking of eosinophils. | Liver-expressed chemokine/CC chemokine ligand 16 attracts eosinophils by interacting with histamine H4 receptor.
Nakayama T, Kato Y, Hieshima K, Nagakubo D, Kunori Y, Fujisawa T, Yoshie O. | 01/21/2010 |