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    CCL18 C-C motif chemokine ligand 18 [ Homo sapiens (human) ]

    Gene ID: 6362, updated on 14-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    The chemokine receptor CCR8 is not a high-affinity receptor for the human chemokine CCL18.

    The chemokine receptor CCR8 is not a high-affinity receptor for the human chemokine CCL18.
    Hussain K, Lim HD, Devkota SR, Kemp-Harper BK, Lane JR, Canals M, Pease JE, Stone MJ., Free PMC Article

    09/19/2024
    CCL18 aggravates atherosclerosis by inducing CCR6-dependent T-cell influx and polarization.

    CCL18 aggravates atherosclerosis by inducing CCR6-dependent T-cell influx and polarization.
    Singh A, Kraaijeveld AO, Curaj A, Wichapong K, Hammerich L, de Jager SCA, Bot I, Atamas SP, van Berkel TJC, Jukema JW, Comerford I, McColl SR, Mees B, Heemskerk JWM, Nicolaes GAF, Hackeng T, Liehn EA, Tacke F, Biessen EAL., Free PMC Article

    09/17/2024
    Pro-Fibrotic Effects of CCL18 on Human Lung Fibroblasts Are Mediated via CCR6.

    Pro-Fibrotic Effects of CCL18 on Human Lung Fibroblasts Are Mediated via CCR6.
    Höhne K, Wagenknecht A, Maier C, Engelhard P, Goldmann T, Schließmann SJ, Plönes T, Trepel M, Eibel H, Müller-Quernheim J, Zissel G., Free PMC Article

    02/15/2024
    CCL18 promotes migration and invasion of multiple myeloma cells and is associated with poor prognosis.

    CCL18 promotes migration and invasion of multiple myeloma cells and is associated with poor prognosis.
    Qiao B, Chen L, Cheng Q, Wang G, Li Q, Zhang B, Li J, Hu Y, Sun C.

    05/17/2023
    Identification and validation of a CCL18-related signature for prediction of overall survival in patients with uveal melanoma.

    Identification and validation of a CCL18-related signature for prediction of overall survival in patients with uveal melanoma.
    Yang B, Fan Y, Chen M, Tang L, Tang X, Li H, Gu A, Liang R, Wu Y.

    05/1/2023
    Adipose tissue specific CCL18 associates with cardiometabolic diseases in non-obese individuals implicating CD4[+] T cells.

    Adipose tissue specific CCL18 associates with cardiometabolic diseases in non-obese individuals implicating CD4(+) T cells.
    Subramanian N, Hofwimmer K, Tavira B, Massier L, Andersson DP, Arner P, Laurencikiene J., Free PMC Article

    04/15/2023
    CCL18 Expression Is Higher in a Glioblastoma Multiforme Tumor than in the Peritumoral Area and Causes the Migration of Tumor Cells Sensitized by Hypoxia.

    CCL18 Expression Is Higher in a Glioblastoma Multiforme Tumor than in the Peritumoral Area and Causes the Migration of Tumor Cells Sensitized by Hypoxia.
    Grochans S, Korbecki J, Simińska D, Żwierełło W, Rzeszotek S, Kolasa A, Kojder K, Tarnowski M, Chlubek D, Baranowska-Bosiacka I., Free PMC Article

    08/27/2022
    IL6 and CCL18 Mediate Cross-talk between VHL-Deficient Kidney Cells and Macrophages during Development of Renal Cell Carcinoma.

    IL6 and CCL18 Mediate Cross-talk between VHL-Deficient Kidney Cells and Macrophages during Development of Renal Cell Carcinoma.
    Nguyen TN, Nguyen-Tran HH, Chen CY, Hsu T., Free PMC Article

    08/13/2022
    Is CCL18 a potential biomarker of type-2 asthma endotypes?

    Is CCL18 a potential biomarker of type-2 asthma endotypes?
    Fouquet H, Giovannelli J, de Nadaï P, Balsamelli J, Berger P, Bourdin A, Chanez P, Fry S, Perez T, Magnan A, Pretolani M, Taillé C, Tsicopoulos A, Chenivesse C, COBRA study group.

    04/30/2022
    Expressions of CXCL12, CXCL10 and CCL18 in Warthin tumors characterized pathologically by having a lymphoid stroma with germinal centers.

    Expressions of CXCL12, CXCL10 and CCL18 in Warthin tumors characterized pathologically by having a lymphoid stroma with germinal centers.
    Mochizuki K, Oishi N, Kawai M, Odate T, Tahara I, Inoue T, Kasai K, Kondo T.

    03/26/2022
    Chemokine CCL18 Promotes Phagocytosis Through Its Receptor CCR8 Rather than PITPNM3 in Human Microglial Cells.

    Chemokine CCL18 Promotes Phagocytosis Through Its Receptor CCR8 Rather than PITPNM3 in Human Microglial Cells.
    Ding D, Zhang L, Liu X, Sun C, He J, Li J, Gao X, Guan F, Zhang L.

    03/19/2022
    [CCL18 Promotes the Invasion of Lung Adenocarcinoma through ANXA2].

    [CCL18 Promotes the Invasion of Lung Adenocarcinoma through ANXA2].
    Deng Z, Xiao Q, Zheng Y, Feng R, Sheng Z, Zhang B., Free PMC Article

    01/29/2022
    Childhood CCL18, CXCL10 and CXCL11 levels differentially relate to and predict allergy development.

    Childhood CCL18, CXCL10 and CXCL11 levels differentially relate to and predict allergy development.
    Huoman J, Haider S, Simpson A, Murray CS, Custovic A, Jenmalm MC., Free PMC Article

    01/15/2022
    Histamine Increases Th2 Cytokine-Induced CCL18 Expression in Human M2 Macrophages.

    Histamine Increases Th2 Cytokine-Induced CCL18 Expression in Human M2 Macrophages.
    Mommert S, Schaper JT, Schaper-Gerhardt K, Gutzmer R, Werfel T., Free PMC Article

    01/8/2022
    Acetylation of ezrin regulates membrane-cytoskeleton interaction underlying CCL18-elicited cell migration.

    Acetylation of ezrin regulates membrane-cytoskeleton interaction underlying CCL18-elicited cell migration.
    Song X, Wang W, Wang H, Yuan X, Yang F, Zhao L, Mullen M, Du S, Zohbi N, Muthusamy S, Cao Y, Jiang J, Xia P, He P, Ding M, Emmett N, Ma M, Wu Q, Green HN, Ding X, Wang D, Wang F, Liu X., Free PMC Article

    08/14/2021
    Expression of CCL-18 and CX3CL1 in Serum, and Their Potential Roles as Two Diagnostic and Prognostic Markers in Chronic Obstructive Pulmonary Disease and Chronic cor Pulmonale (COPD&CCP): a Pilot Study.

    Expression of CCL-18 and CX3CL1 in Serum, and Their Potential Roles as Two Diagnostic and Prognostic Markers in Chronic Obstructive Pulmonary Disease and Chronic cor Pulmonale (COPD&CCP): a Pilot Study.
    Xu QH, Huang SP, Li WL, Ye XY, Lin XH, Wu YL, Chen XF, Zhuang XB.

    07/24/2021
    CCL18-induced LINC00319 promotes proliferation and metastasis in oral squamous cell carcinoma via the miR-199a-5p/FZD4 axis.

    CCL18-induced LINC00319 promotes proliferation and metastasis in oral squamous cell carcinoma via the miR-199a-5p/FZD4 axis.
    Jiang X, Liu J, Li S, Jia B, Huang Z, Shen J, Luo H, Zhao J., Free PMC Article

    05/15/2021
    CCL18 in the Progression of Cancer.

    CCL18 in the Progression of Cancer.
    Korbecki J, Olbromski M, Dzięgiel P., Free PMC Article

    03/6/2021
    MiR-484 suppressed proliferation, migration, invasion and induced apoptosis of gastric cancer via targeting CCL-18.

    MiR-484 suppressed proliferation, migration, invasion and induced apoptosis of gastric cancer via targeting CCL-18.
    Liu J, Li SM., Free PMC Article

    03/6/2021
    Association between serum CCL-18 and IL-23 concentrations and disease progression of chronic obstructive pulmonary disease.

    Association between serum CCL-18 and IL-23 concentrations and disease progression of chronic obstructive pulmonary disease.
    Rong B, Fu T, Rong C, Liu W, Li K, Liu H., Free PMC Article

    02/2/2021
    CCL18-NIR1 promotes oral cancer cell growth and metastasis by activating the JAK2/STAT3 signaling pathway.

    CCL18-NIR1 promotes oral cancer cell growth and metastasis by activating the JAK2/STAT3 signaling pathway.
    Jiang X, Huang Z, Sun X, Zheng X, Liu J, Shen J, Jia B, Luo H, Mai Z, Chen G, Zhao J., Free PMC Article

    02/2/2021
    CCL18 overexpression predicts a worse prognosis in oral squamous cell carcinoma (OSCC).

    CCL18 overexpression predicts a worse prognosis in oral squamous cell carcinoma (OSCC).
    Mao L, Zhuang R, Qin L, Han Z, Huang X, Chen R, Su Y, Ge L, Yang J, Li J, Wang X.

    09/12/2020
    CCL18 is specific for disease activity in LoS thereby providing relevance as a biomarker for this debilitating disease.

    The identification of CCL18 as biomarker of disease activity in localized scleroderma.
    Mertens JS, de Jong EMGJ, van den Hoogen LL, Wienke J, Thurlings RM, Seyger MMB, Hoppenreijs EPAH, Wijngaarde CA, van Vlijmen-Willems IMJJ, van den Bogaard E, Giovannone B, van Wijk F, van Royen-Kerkhof A, Marut W, Radstake TRD.

    07/25/2020
    CCL18 promotes the metastasis of squamous cell carcinoma of the head and neck through MTDH-NF-kappaB signaling pathway.

    CCL18 promotes the metastasis of squamous cell carcinoma of the head and neck through MTDH-NF-κB signalling pathway.
    Qin Y, Wang J, Zhu G, Li G, Tan H, Chen C, Pi L, She L, Chen X, Wei M, Li Z, Liu Z, Huang D, Liu Y, Zhang X., Free PMC Article

    07/18/2020
    The Gs-coupled receptor GPR30 plays an important role in the signaling pathway of CCL18. CCL18 and estradiol may not lead to the same signaling pathway after activating GPR30.

    Interaction Between CCL18 and GPR30 Differs from the Interaction Between Estradiol and GPR30.
    Schmidt-Wolf R, Zissel G.

    06/13/2020
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