| Thermodynamic Evolution of a Metamorphic Protein: A Theoretical-Computational Study of Human Lymphotactin. | Thermodynamic Evolution of a Metamorphic Protein: A Theoretical-Computational Study of Human Lymphotactin.
Zanetti-Polzi L, Daidone I, Iacobucci C, Amadei A., Free PMC Article | 06/22/2023 |
| XCL1, a serum biomarker in neurological diseases; HTLV-1-associated myelopathy and multiple sclerosis. | XCL1, a serum biomarker in neurological diseases; HTLV-1-associated myelopathy and multiple sclerosis.
Saeidi M, Vahidi Z, Nahayati MA, Rezaiyan MK, Zemorshidi F, Mahdifar M, Hafezi F, Moghadam SM, Saghi E, Akbarpour E, Boostani R, Rafatpanah H. | 01/28/2023 |
| XCL1 Aggravates Diabetic Nephropathy-Mediated Renal Glomerular Endothelial Cell Apoptosis and Inflammatory Response via Regulating p53/Nuclear Factor-Kappa B Pathway. | XCL1 Aggravates Diabetic Nephropathy-Mediated Renal Glomerular Endothelial Cell Apoptosis and Inflammatory Response via Regulating p53/Nuclear Factor-Kappa B Pathway.
Zhang Y, Chen X, Fan Y, Liu J, Yuan L. | 03/26/2022 |
| Specific binding-induced modulation of the XCL1 metamorphic equilibrium. | Specific binding-induced modulation of the XCL1 metamorphic equilibrium.
Dishman AF, Peterson FC, Volkman BF., Free PMC Article | 01/22/2022 |
| Involvement of the ERK/HIF-1alpha/EMT Pathway in XCL1-Induced Migration of MDA-MB-231 and SK-BR-3 Breast Cancer Cells. | Involvement of the ERK/HIF-1α/EMT Pathway in XCL1-Induced Migration of MDA-MB-231 and SK-BR-3 Breast Cancer Cells.
Do HTT, Cho J., Free PMC Article | 03/13/2021 |
| Evolution of fold switching in a metamorphic protein. | Evolution of fold switching in a metamorphic protein.
Dishman AF, Tyler RC, Fox JC, Kleist AB, Prehoda KE, Babu MM, Peterson FC, Volkman BF., Free PMC Article | 02/13/2021 |
| XCL1 expression correlates with CD8-positive T cells infiltration and PD-L1 expression in squamous cell carcinoma arising from mature cystic teratoma of the ovary. | XCL1 expression correlates with CD8-positive T cells infiltration and PD-L1 expression in squamous cell carcinoma arising from mature cystic teratoma of the ovary.
Tamura R, Yoshihara K, Nakaoka H, Yachida N, Yamaguchi M, Suda K, Ishiguro T, Nishino K, Ichikawa H, Homma K, Kikuchi A, Ueda Y, Takei Y, Fujiwara H, Motoyama T, Okuda S, Wakai T, Inoue I, Enomoto T., Free PMC Article | 11/28/2020 |
| The systemic exercise-released chemokine lymphotactin/XCL1 modulates in vitro adult hippocampal precursor cell proliferation and neuronal differentiation. | The systemic exercise-released chemokine lymphotactin/XCL1 modulates in vitro adult hippocampal precursor cell proliferation and neuronal differentiation.
Leiter O, Bernas SN, Seidemann S, Overall RW, Horenburg C, Kowal S, Kempermann G, Walker TL., Free PMC Article | 11/21/2020 |
| Diepoxybutane induces the expression of a novel p53-target gene XCL1 that mediates apoptosis in exposed human lymphoblasts. | Diepoxybutane induces the expression of a novel p53-target gene XCL1 that mediates apoptosis in exposed human lymphoblasts.
Ewunkem AJ, Deve M, Harrison SH, Muganda PM., Free PMC Article | 10/10/2020 |
| Structure-function guided modeling of chemokine-GPCR specificity for the chemokine XCL1 and its receptor XCR1. | Structure-function guided modeling of chemokine-GPCR specificity for the chemokine XCL1 and its receptor XCR1.
Fox JC, Thomas MA, Dishman AF, Larsen O, Nakayama T, Yoshie O, Rosenkilde MM, Volkman BF., Free PMC Article | 08/15/2020 |
| Study supports the genetic effect on preventing breast cancer survival through XCL1-induced DC1 recruitment in tumor microenvironment. | A functional variant near XCL1 gene improves breast cancer survival via promoting cancer immunity.
Chou WC, Hsiung CN, Chen WT, Tseng LM, Wang HC, Chu HW, Hou MF, Yu JC, Shen CY. | 05/23/2020 |
| XCL1-XCR1 chemokine pathway promotes trophoblast invasion by increasing matrix metalloproteinase activity in human first-trimester placenta | XCL1-XCR1 pathway promotes trophoblast invasion at maternal-fetal interface by inducing MMP-2/MMP-9 activity.
Zhang SM, Tian FJ, Zeng WH, Ma XL, Ren JB, Lin Y. | 11/2/2019 |
| higher serum XCL1 levels at diagnosis and their progressive decline throughout chemotherapy could be correlated with higher survival. | The prognostic significance of serum XCL1 concentration in patients with acute lymphoblastic leukemia: a pilot study.
Gutiérrez-Aguirre CH, Flores-Jiménez JA, Alatorre-Ricardo J, Cantú-Rodríguez OG, Rosas-Taraco A, Salazar-Riojas R, Jaime-Pérez JC, Sánchez-Cárdenas M, López-Silva L, Martínez-Castilla AM, Salinas-Carmona MC, Gómez-Almaguer D. | 12/2/2017 |
| This study defines a Glycosaminoglycan binding surface on XCL1 dimer that includes residues that are important for HIV-1 inhibition. | Examination of Glycosaminoglycan Binding Sites on the XCL1 Dimer.
Fox JC, Tyler RC, Peterson FC, Dyer DP, Zhang F, Linhardt RJ, Handel TM, Volkman BF., Free PMC Article | 07/30/2016 |
| Electrostatics and Hydrophobic Effects in the Metamorphic Protein Human Lymphotactin | Interplay of Electrostatics and Hydrophobic Effects in the Metamorphic Protein Human Lymphotactin.
Korkmaz EN, Volkman BF, Cui Q. | 05/28/2016 |
| XCL1 acts via direct interaction with the external viral envelope glycoprotein, gp120, to block HIV-1 infection | Structural Determinants for the Selective Anti-HIV-1 Activity of the All-β Alternative Conformer of XCL1.
Guzzo C, Fox JC, Miao H, Volkman BF, Lusso P., Free PMC Article | 04/30/2016 |
| analysis of XCL1 and XCL2, members of the C-chemokine subfamily, in the immune system | Structural and agonist properties of XCL2, the other member of the C-chemokine subfamily.
Fox JC, Nakayama T, Tyler RC, Sander TL, Yoshie O, Volkman BF., Free PMC Article | 11/14/2015 |
| identified 13 ADCC-activated genes. Six gene expression assays including 8 of the 13 genes (CCL3, CCL4/CCL4L1/CCL4L2, CD160, IFNG, NR4A3 and XCL1/XCL2) were analyzed in 127 kidney biopsies | Genes associated with antibody-dependent cell activation are overexpressed in renal biopsies from patients with antibody-mediated rejection.
Suviolahti E, Ge S, Nast CC, Mirocha J, Karasyov A, White M, Jordan SC, Toyoda M. | 09/26/2015 |
| XCL1 displays antimicrobial activity against E. coli and S. aureus. | Many chemokines including CCL20/MIP-3alpha display antimicrobial activity.
Yang D, Chen Q, Hoover DM, Staley P, Tucker KD, Lubkowski J, Oppenheim JJ. | 09/24/2014 |
| XCL1-mediated inhibition is associated with direct interaction of the chemokine with the HIV-1 envelope. | The CD8-derived chemokine XCL1/lymphotactin is a conformation-dependent, broad-spectrum inhibitor of HIV-1.
Guzzo C, Fox J, Lin Y, Miao H, Cimbro R, Volkman BF, Fauci AS, Lusso P., Free PMC Article | 09/6/2014 |
| In native annulus fibrosus tissue homeostasis and repair, CXCR3 is evident, whereas XCL1 could not be detected. | The chemokines CXCL10 and XCL1 recruit human annulus fibrosus cells.
Hegewald AA, Neumann K, Kalwitz G, Freymann U, Endres M, Schmieder K, Kaps C, Thomé C. | 09/29/2012 |
| The expression patterns of XCR1 and XCL1 were conserved in human and mice blood cells, including certain dendritic cell subsets. | Conservation of a chemokine system, XCR1 and its ligand, XCL1, between human and mice.
Yamazaki C, Miyamoto R, Hoshino K, Fukuda Y, Sasaki I, Saito M, Ishiguchi H, Yano T, Sugiyama T, Hemmi H, Tanaka T, Hamada E, Hirashima T, Amakawa R, Fukuhara S, Nomura S, Ito T, Kaisho T. | 08/23/2010 |
| Data indicated increased expression of XCL1 in CD4+ and CD8+ T cells in Wegener's granulomatosis (WG), and suggest that XCL1 might be a key modulator of T cell recruitment in WG. | Expression and function of the C-class chemokine lymphotactin (XCL1) in Wegener's granulomatosis.
Blaschke S, Brandt P, Wessels JT, Müller GA. | 02/8/2010 |
| The monocyte-derived dendritic cells can express Lptn mRNA in a maturation-dependent manner. | [Preliminary study on lymphotactin expression of monocyte-derived dendritic cells].
Lu XB, Xie HL, Huang HW, Shi ZM, Xiong JH, Pan ZY. | 01/21/2010 |
| ATAC Is a GCN5/PCAF-containing acetylase complex with a novel NC2-like histone fold module that interacts with the TATA-binding protein | Human ATAC Is a GCN5/PCAF-containing acetylase complex with a novel NC2-like histone fold module that interacts with the TATA-binding protein.
Wang YL, Faiola F, Xu M, Pan S, Martinez E., Free PMC Article | 01/21/2010 |