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    PRDM1 PR/SET domain 1 [ Homo sapiens (human) ]

    Gene ID: 639, updated on 12-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    PRDM1 promotes nucleus pulposus cell pyroptosis leading to intervertebral disc degeneration via activating CASP1 transcription.

    PRDM1 promotes nucleus pulposus cell pyroptosis leading to intervertebral disc degeneration via activating CASP1 transcription.
    Yu C, Li J, Kuang W, Ni S, Cao Y, Duan Y., Free PMC Article

    10/30/2024
    PTIP epigenetically regulates DNA damage-induced cell cycle arrest by upregulating PRDM1.

    PTIP epigenetically regulates DNA damage-induced cell cycle arrest by upregulating PRDM1.
    Nakata Y, Nagasawa S, Sera Y, Yamasaki N, Kanai A, Kobatake K, Ueda T, Koizumi M, Manabe I, Kaminuma O, Honda H., Free PMC Article

    08/16/2024
    Human split hand/foot variants are not as functional as wildtype human PRDM1 in the rescue of craniofacial defects.

    Human split hand/foot variants are not as functional as wildtype human PRDM1 in the rescue of craniofacial defects.
    Truong BT, Shull LC, Zepeda BJ, Lencer E, Artinger KB.,

    03/13/2024
    Pro-Inflammatory of PRDM1/SIRT2/NLRP3 Axis in Monosodium Urate-Induced Acute Gouty Arthritis.

    Pro-Inflammatory of PRDM1/SIRT2/NLRP3 Axis in Monosodium Urate-Induced Acute Gouty Arthritis.
    Zhao Q, Xia N, Xu J, Wang Y, Feng L, Su D, Cheng Z., Free PMC Article

    01/4/2024
    Exploring the putative role of PRDM1 and PRDM2 transcripts as mediators of T lymphocyte activation.

    Exploring the putative role of PRDM1 and PRDM2 transcripts as mediators of T lymphocyte activation.
    Di Zazzo E, Rienzo M, Casamassimi A, De Rosa C, Medici N, Gazzerro P, Bifulco M, Abbondanza C., Free PMC Article

    03/28/2023
    Expression of B lymphocyte-induced maturation protein 1 (Blimp-1) in keratinocyte and cytokine signalling drives human Th17 response in psoriasis.

    Expression of B lymphocyte-induced maturation protein 1 (Blimp-1) in keratinocyte and cytokine signalling drives human Th17 response in psoriasis.
    da Costa LCO, Gardinassi LG, Veras FP, Milanezi C, Ramalho LNZ, Benevides L, Alves-Filho JC, da Silva JS, da Silva Souza C.

    03/23/2023
    BLIMP1 and NR4A3 transcription factors reciprocally regulate antitumor CAR T cell stemness and exhaustion.

    BLIMP1 and NR4A3 transcription factors reciprocally regulate antitumor CAR T cell stemness and exhaustion.
    Jung IY, Narayan V, McDonald S, Rech AJ, Bartoszek R, Hong G, Davis MM, Xu J, Boesteanu AC, Barber-Rotenberg JS, Plesa G, Lacey SF, Jadlowsky JK, Siegel DL, Hammill DM, Cho-Park PF, Berger SL, Haas NB, Fraietta JA., Free PMC Article

    01/28/2023
    The role of PRDM1 gene polymorphism in the progression of hepatocellular carcinoma in Egyptian patients.

    The role of PRDM1 gene polymorphism in the progression of hepatocellular carcinoma in Egyptian patients.
    Mohamed AA, Esmail OE, Ibrahim AMA, Makled S, Al-Hussain E, Elsaid A, Alboraie M, El-Awady RR.

    01/21/2023
    Regulatory network of BLIMP1, IRF4, and XBP1 triad in plasmacytic differentiation and multiple myeloma pathogenesis.

    Regulatory network of BLIMP1, IRF4, and XBP1 triad in plasmacytic differentiation and multiple myeloma pathogenesis.
    Tang TF, Chan YT, Cheong HC, Cheok YY, Anuar NA, Looi CY, Gan GG, Wong WF.

    10/1/2022
    Blimp-1 is a prognostic indicator for progression of cervical intraepithelial neoplasia grade 2.

    Blimp-1 is a prognostic indicator for progression of cervical intraepithelial neoplasia grade 2.
    Saito M, Rajesh A, Innes C, van der Griend R, Fitzgerald P, Simcock B, Sykes P, Hibma M., Free PMC Article

    07/23/2022
    O-GlcNAcylation of Blimp-1 in Lymphocytes Inhibits Its Transcriptional Function and Is Associated with Migration and Invasion of Breast Cancer Cells.

    O-GlcNAcylation of Blimp-1 in Lymphocytes Inhibits Its Transcriptional Function and Is Associated with Migration and Invasion of Breast Cancer Cells.
    Chen YF, Shao GC, Li J, Yang AQ, Li J, Ye XS.

    07/9/2022
    PRDM1 Drives Human Primary T Cell Hyporesponsiveness by Altering the T Cell Transcriptome and Epigenome.

    PRDM1 Drives Human Primary T Cell Hyporesponsiveness by Altering the T Cell Transcriptome and Epigenome.
    Guo H, Wang M, Wang B, Guo L, Cheng Y, Wang Z, Sun YQ, Wang Y, Chang YJ, Huang XJ., Free PMC Article

    05/21/2022
    The genetic deletion and protein expression of PRDM1 and its clinical implications in diffuse large B cell lymphoma: A retrospective cohort study in China.

    The genetic deletion and protein expression of PRDM1 and its clinical implications in diffuse large B cell lymphoma: A retrospective cohort study in China.
    Nong L, Zheng Y, Li X, Li D, Liang L, Wang W, Li T.

    05/7/2022
    Genetic ablation of PRDM1 in antitumor T cells enhances therapeutic efficacy of adoptive immunotherapy.

    Genetic ablation of PRDM1 in antitumor T cells enhances therapeutic efficacy of adoptive immunotherapy.
    Yoshikawa T, Wu Z, Inoue S, Kasuya H, Matsushita H, Takahashi Y, Kuroda H, Hosoda W, Suzuki S, Kagoya Y.

    04/16/2022
    Genome-wide DNA methylation analysis of pulmonary function in middle and old-aged Chinese monozygotic twins.

    Genome-wide DNA methylation analysis of pulmonary function in middle and old-aged Chinese monozygotic twins.
    Wang T, Wang W, Li W, Duan H, Xu C, Tian X, Zhang D., Free PMC Article

    03/19/2022
    Evaluation of MicroRNA-125b-5p and Transcription Factors BLIMP1 and IRF4 Expression in Unsolved Common Variable Immunodeficiency Patients.

    Evaluation of MicroRNA-125b-5p and Transcription Factors BLIMP1 and IRF4 Expression in Unsolved Common Variable Immunodeficiency Patients.
    Hamidi Esfahani Z, Yazdani R, Shahkarami S, Babaha F, Abolhassani H, Sadr M, Pourfathollah AA, Aghamohammadi A.

    03/12/2022
    Dysregulated MDR1 by PRDM1/Blimp1 Is Involved in the Doxorubicin Resistance of Non-Germinal Center B-Cell-Like Diffuse Large B-Cell Lymphoma.

    Dysregulated MDR1 by PRDM1/Blimp1 Is Involved in the Doxorubicin Resistance of Non-Germinal Center B-Cell-Like Diffuse Large B-Cell Lymphoma.
    Qing K, Jin Z, Xu Z, Wang W, Li X, Zhang Y, Wang L, Zhu H, Xiang R, Wu S, Li R, Jiang G, Xue K, Li J.

    03/12/2022
    IL-21 enhances STAT3/Blimp-1 signaling pathway in B cells and contributes to plasma cell differentiation in newly diagnosed patients with myasthenia gravis.

    IL-21 enhances STAT3/Blimp-1 signaling pathway in B cells and contributes to plasma cell differentiation in newly diagnosed patients with myasthenia gravis.
    Xu Y, Huang X, Li F, Liu T, Yang T, Chen F, Zhu J, Pan M, Zhang Y, Wang Y, Fu L, Xiao C, Geng D.

    01/1/2022
    Coupled Antigen and BLIMP1 Asymmetric Division With a Large Segregation Between Daughter Cells Recapitulates the Temporal Transition From Memory B Cells to Plasma Cells and a DZ-to-LZ Ratio in the Germinal Center.

    Coupled Antigen and BLIMP1 Asymmetric Division With a Large Segregation Between Daughter Cells Recapitulates the Temporal Transition From Memory B Cells to Plasma Cells and a DZ-to-LZ Ratio in the Germinal Center.
    Merino Tejero E, Lashgari D, García-Valiente R, He J, Robert PA, Meyer-Hermann M, Guikema JEJ, Hoefsloot H, van Kampen AHC., Free PMC Article

    12/25/2021
    Increased Expression of B Lymphocyte Induced Maturation Protein 1 (BLIMP1) in Patients with Common Variable Immunodeficiency (CVID).

    Increased Expression of B Lymphocyte Induced Maturation Protein 1 (BLIMP1) in Patients with Common Variable Immunodeficiency (CVID).
    Farrokhi S, Abbasi-Rad F, Esmaeil N, Sherkat R, Yazdani R, Afshar-Ghasemlou S, Fekrvand S, Ganjalikhani-Hakemi M.

    11/13/2021
    Genetic manipulation of primary human natural killer cells to investigate the functional and oncogenic roles of PRDM1.

    Genetic manipulation of primary human natural killer cells to investigate the functional and oncogenic roles of PRDM1.
    Dong G, Li Y, Lee L, Liu X, Shi Y, Liu X, Bouska A, Gong Q, Kong L, Wang J, Lou CH, McKeithan TW, Iqbal J, Chan WC., Free PMC Article

    10/30/2021
    [Expression and Significance of BLIMP-1 in Regulatory T Cells of Children with Aplastic Anemia].

    [Expression and Significance of BLIMP-1 in Regulatory T Cells of Children with Aplastic Anemia].
    Huang LF, Huang JB, Tang NN, Xue HM, Zhu CM, Li CK, Chen C.

    08/14/2021
    Mucosal ribosomal stress-induced PRDM1 promotes chemoresistance via stemness regulation.

    Mucosal ribosomal stress-induced PRDM1 promotes chemoresistance via stemness regulation.
    Kim J, Moon Y., Free PMC Article

    08/14/2021
    Genetic association of polymorphisms at the intergenic region between PRDM1 and ATG5 with hepatitis B virus infection in Han Chinese patients.

    Genetic association of polymorphisms at the intergenic region between PRDM1 and ATG5 with hepatitis B virus infection in Han Chinese patients.
    Li N, Fan X, Wang X, Zhang X, Zhang K, Han Q, Lv Y, Liu Z.

    07/17/2021
    BLIMP-1 Mediated Downregulation of TAK1 and p53 Molecules Is Crucial in the Pathogenesis of Kala-Azar.

    BLIMP-1 Mediated Downregulation of TAK1 and p53 Molecules Is Crucial in the Pathogenesis of Kala-Azar.
    Saha G, Chiranjivi AK, Khamar BM, Prerna K, Kumar M, Dubey VK., Free PMC Article

    06/26/2021
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