| TP53AIP1 induce autophagy via the AKT/mTOR signaling pathway in the breast cancer cells. | TP53AIP1 induce autophagy via the AKT/mTOR signaling pathway in the breast cancer cells.
Liu S, Xu T, Chen X, Tang L, Li L, Zhang L, Yang Y, Huang J., Free PMC Article | 09/4/2024 |
| Bioinformatic analysis identified TP53AIP1 as a direct target for miR-505. | Extracellular vesicle‑delivered miR‑505‑5p, as a diagnostic biomarker of early lung adenocarcinoma, inhibits cell apoptosis by targeting TP53AIP1.
Fang H, Liu Y, He Y, Jiang Y, Wei Y, Liu H, Gong Y, An G. | 08/17/2019 |
| results show that constitutional truncating TP53AIP1 mutations predispose to CMM in the French population | Truncating mutations of TP53AIP1 gene predispose to cutaneous melanoma.
Benfodda M, Gazal S, Descamps V, Basset-Seguin N, Deschamps L, Thomas L, Lebbe C, Saiag P, Zanetti R, Sacchetto L, Chiorino G, Scatolini M, Grandchamp B, Bensussan A, Soufir N. | 09/29/2018 |
| Data indicate that p53-regulated apoptosis-inducing protein 1 (p53AIP1) inhibits the proliferation of PC-3M cells, arrests cell cycle at S/G2-M phase, decreases the abilities of invasion and migration and promotes cell apoptosis. | [Effect of p53-regulated apoptosis-inducing protein 1 transfection on the biological characteristics of PC-3M human prostate cancer cells].
Lin X, Zhao Q, Yin X, Tian R, Li F, Gao J, Yu J. | 10/4/2014 |
| These studies indicate the critical role of p53AIP1 under DNA damaging stresses for cell fate determination in rheumatoid arthritis-fibroblast-like synovioctes containing the p53R248Q mutation. | Anti-apoptotic roles for the mutant p53R248Q through suppression of p53-regulated apoptosis-inducing protein 1 in the RA-derived fibroblast-like synoviocyte cell line MH7A.
Igarashi H, Hirano H, Yahagi A, Saika T, Ishihara K. | 03/15/2014 |
| Apak competes with p53 for binding to inhibit p53AIP1 expression. | Apak competes with p53 for direct binding to intron 1 of p53AIP1 to regulate apoptosis.
Yuan L, Tian C, Wang H, Song S, Li D, Xing G, Yin Y, He F, Zhang L., Free PMC Article | 08/11/2012 |
| large sample size of the combined cohort rejects a high-risk effect greater than 2.2 and indicates a limited role of TP53AIP1 in prostate cancer predisposition | Prostate cancer risk is not altered by TP53AIP1 germline mutations in a German case-control series.
Luedeke M, Coinac I, Linnert CM, Bogdanova N, Rinckleb AE, Schrader M, Vogel W, Hoegel J, Meyer A, Dörk T, Maier C., Free PMC Article | 08/4/2012 |
| Observational study of gene-disease association. (HuGE Navigator) | Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study.
Flachsbart F, Franke A, Kleindorp R, Caliebe A, Blanché H, Schreiber S, Nebel A. | 12/5/2010 |
| Data suggest that the combination of p53AIP1 and survivin gene expression may be a powerful tool to stratify subgroups with better or worse prognosis from the variable non-small cell lung cancer population. | Combination of p53AIP1 and survivin expression is a powerful prognostic marker in non-small cell lung cancer.
Yamashita S, Chujo M, Miyawaki M, Tokuishi K, Anami K, Yamamoto S, Kawahara K., Free PMC Article | 01/21/2010 |
| Insufficient expression of p53AIP1 may play a role in gastric carcinogenesis in patients infected with H. pylori infection. | Insights in gastric carcinogenesis from Helicobacter pylori infection.
Daniele B. | 01/21/2010 |
| Insufficient expression of p53AIP1 may play a role in gastric carcinogenesis in patients infected with H. pylori infection. | Difference of p53AIP1 mRNA expression in gastric mucosa between patients with gastric cancer and chronic gastritis infected with Helicobacter pylori.
Sawaya M, Yoshimura T, Shimoyama T, Munakata A, Fukuda S. | 01/21/2010 |
| p53AIP1 gene is important for non-small cell lung cancer progression and may be a possible prognostic marker | p53AIP1 expression can be a prognostic marker in non-small cell lung cancer.
Yamashita SI, Masuda Y, Yoshida N, Matsuzaki H, Kurizaki T, Haga Y, Ikei S, Miyawaki M, Kawano Y, Chujyo M, Kawahara K. | 01/21/2010 |
| p53AIP1 regulates the mitochondrial apoptotic pathway. | p53AIP1 regulates the mitochondrial apoptotic pathway.
Matsuda K, Yoshida K, Taya Y, Nakamura K, Nakamura Y, Arakawa H. | 01/21/2010 |
| The expression of Ki67 and p53 in various forms of leukoplakia point to the increasing instability of the genome in parallel with the severity of leukoplakia. | Changes in apoptosis and mitotic index, p53 and Ki67 expression in various types of oral leukoplakia.
Kövesi G, Szende B. | 01/21/2010 |
| expression of the p53 mutant, R248Q, in liver cancer cells may enhance their drug resistance and upregulation of P-glycoprotein activity may contribute to this protective effect. | Mutant p53 expression enhances drug resistance in a hepatocellular carcinoma cell line.
Chan KT, Lung ML. | 01/21/2010 |
| Roscovitine induced up-regulation of p53AIP1 protein and the depolarization of mitochondrial potential. | Roscovitine-induced up-regulation of p53AIP1 protein precedes the onset of apoptosis in human MCF-7 breast cancer cells.
Wesierska-Gadek J, Gueorguieva M, Horky M. | 01/21/2010 |