| Genome-Wide Association Study Identifies IFIH1 and HLA-DQB1*05:02 Loci Associated With Anti-NMDAR Encephalitis. | Genome-Wide Association Study Identifies IFIH1 and HLA-DQB1*05:02 Loci Associated With Anti-NMDAR Encephalitis.
Liu X, Zheng X, Shu Y, Qu X, Wang Q, Liu X, Hu FY, Liu J, Lian Y, He BM, Li C, Zhou D, Qiu W, Sun L, Hong Z., Free PMC Article | 04/17/2024 |
| Contrasting functions of ATP hydrolysis by MDA5 and LGP2 in viral RNA sensing. | Contrasting functions of ATP hydrolysis by MDA5 and LGP2 in viral RNA sensing.
Singh R, Wu Y, Herrero Del Valle A, Leigh KE, Mong S, Cheng MTK, Ferguson BJ, Modis Y., Free PMC Article | 04/15/2024 |
| Hepatitis C virus NS5B triggers an MDA5-mediated innate immune response by producing dsRNA without the replication of viral genomes. | Hepatitis C virus NS5B triggers an MDA5-mediated innate immune response by producing dsRNA without the replication of viral genomes.
Dansako H, Ikeda M, Ariumi Y, Togashi Y, Kato N. | 03/15/2024 |
| Global trends in research of melanoma differentiation-associated gene 5: a bibliometric analysis from 2002 to 2022. | Global trends in research of melanoma differentiation-associated gene 5: a bibliometric analysis from 2002 to 2022.
Yuan X, Shi J, Peng Z, Peng L, Zhou S, Wu C, Zhao J, Xu D, Li M, Wang Q, Zeng X. | 03/7/2024 |
| Histone H1.2 Inhibited EMCV Replication through Enhancing MDA5-Mediated IFN-beta Signaling Pathway. | Histone H1.2 Inhibited EMCV Replication through Enhancing MDA5-Mediated IFN-β Signaling Pathway.
Song Y, Li H, Lian R, Dou X, Li S, Xie J, Li X, Feng R, Li Z., Free PMC Article | 02/28/2024 |
| MDA5 Enhances Invasive Candida albicans Infection by Regulating Macrophage Apoptosis and Phagocytosis/Killing Functions. | MDA5 Enhances Invasive Candida albicans Infection by Regulating Macrophage Apoptosis and Phagocytosis/Killing Functions.
Chen Y, Jiang Q, Qing F, Xue J, Xiao Q, He W, Sui L, Liu Z. | 02/1/2024 |
| Anti-melanoma Differentiation-associated Gene 5 Antibody-positive Dermatomyositis Presenting as Refractory Gingivitis at the First Clinical Manifestation. | Anti-melanoma Differentiation-associated Gene 5 Antibody-positive Dermatomyositis Presenting as Refractory Gingivitis at the First Clinical Manifestation.
Kawakami E, Uchida T, Iwamoto N, Hara K, Egashira K, Kawakami A., Free PMC Article | 01/8/2024 |
| Coxsackievirus A6 2C protein antagonizes IFN-beta production through MDA5 and RIG-I depletion. | Coxsackievirus A6 2C protein antagonizes IFN-β production through MDA5 and RIG-I depletion.
Wang S-H, Du J, Yu J, Zhao Y, Wang Y, Hua S, Zhao K., Free PMC Article | 12/6/2023 |
| SARS-CoV-2 Nsp8 suppresses MDA5 antiviral immune responses by impairing TRIM4-mediated K63-linked polyubiquitination. | SARS-CoV-2 Nsp8 suppresses MDA5 antiviral immune responses by impairing TRIM4-mediated K63-linked polyubiquitination.
Zhang X, Yang Z, Pan T, Sun Q, Chen Q, Wang PH, Li X, Kuang E., Free PMC Article | 12/5/2023 |
| The IFIH1/MDA5 rs1990760 Gene Variant (946Thr) Differentiates Early- vs. Late-Onset Skin Disease and Increases the Risk of Arthritis in a Spanish Cohort of Psoriasis. | The IFIH1/MDA5 rs1990760 Gene Variant (946Thr) Differentiates Early- vs. Late-Onset Skin Disease and Increases the Risk of Arthritis in a Spanish Cohort of Psoriasis.
Coto-Segura P, Vázquez-Coto D, Velázquez-Cuervo L, García-Lago C, Coto E, Queiro R., Free PMC Article | 11/7/2023 |
| Predictors of rapidly progressive interstitial lung disease and prognosis in Chinese patients with anti-melanoma differentiation-associated gene 5-positive dermatomyositis. | Predictors of rapidly progressive interstitial lung disease and prognosis in Chinese patients with anti-melanoma differentiation-associated gene 5-positive dermatomyositis.
Li M, Zhao X, Liu B, Zhao Y, Li X, Ma Z, Yang Q., Free PMC Article | 09/26/2023 |
| Association of the rs1990760, rs3747517, and rs10930046 polymorphisms in the IFIH1 gene with susceptibility to autoimmune diseases: a meta-analysis. | Association of the rs1990760, rs3747517, and rs10930046 polymorphisms in the IFIH1 gene with susceptibility to autoimmune diseases: a meta-analysis.
Xiao Z, Luo S, Zhou Y, Pang H, Yin W, Qin J, Xie Z, Zhou Z., Free PMC Article | 07/12/2023 |
| Association of IFIH1 and DDX58 genes polymorphism with susceptibility to COVID-19. | Association of IFIH1 and DDX58 genes polymorphism with susceptibility to COVID-19.
Feizollahi P, Zamanian MH, Falahi S, Salari F, Mahmoudi Z, Faryadi E, Gorgin Karaji A, Rezaiemanesh A. | 06/29/2023 |
| Genetic variants of IFIH1 and DHX58 affect the chronicity of hepatitis C in the Chinese Han population. | Genetic variants of IFIH1 and DHX58 affect the chronicity of hepatitis C in the Chinese Han population.
Huang P, Wu JJ, Zhang JW, Hou YQ, Zhu P, Yin R, Yu RB, Zhang Y, Yue M, Hou W., Free PMC Article | 06/24/2023 |
| WDFY4 polymorphisms in Chinese patients with anti-MDA5 dermatomyositis is associated with rapid progressive interstitial lung disease. | WDFY4 polymorphisms in Chinese patients with anti-MDA5 dermatomyositis is associated with rapid progressive interstitial lung disease.
Guo L, Zhang X, Pu W, Zhao J, Wang K, Zhang D, Hong S, Ma Y, Wang X, Ye S, Guo Q, Wang J. | 06/13/2023 |
| [Risk Factors of Rapidly Progressive Interstitial Lung Disease in Patients With Anti-Melanoma Differentiation-Associated Gene 5 Antibody-Positive Dermatomyositis]. | [Risk Factors of Rapidly Progressive Interstitial Lung Disease in Patients With Anti-Melanoma Differentiation-Associated Gene 5 Antibody-Positive Dermatomyositis].
Han YY, Jiang T, Zhang ZH, Li W, Jiang YD, Lu CC, Fei Y, Chen B., Free PMC Article | 04/1/2023 |
| Age-dependent effect of the IFIH1/MDA5 gene variants on the risk of critical COVID-19. | Age-dependent effect of the IFIH1/MDA5 gene variants on the risk of critical COVID-19.
Muñiz-Banciella MG, Albaiceta GM, Amado-Rodríguez L, Del Riego ES, Alonso IL, López-Martínez C, Martín-Vicente P, García-Clemente M, Hermida-Valverde T, Enríquez-Rodriguez AI, Hernández-González C, Cuesta-Llavona E, Alvarez V, Gómez J, Coto E., Free PMC Article | 03/28/2023 |
| Polymorphisms in ACE1, TMPRSS2, IFIH1, IFNAR2, and TYK2 Genes Are Associated with Worse Clinical Outcomes in COVID-19. | Polymorphisms in ACE1, TMPRSS2, IFIH1, IFNAR2, and TYK2 Genes Are Associated with Worse Clinical Outcomes in COVID-19.
Dieter C, de Almeida Brondani L, Lemos NE, Schaeffer AF, Zanotto C, Ramos DT, Girardi E, Pellenz FM, Camargo JL, Moresco KS, da Silva LL, Aubin MR, de Oliveira MS, Rech TH, Canani LH, Gerchman F, Leitão CB, Crispim D., Free PMC Article | 02/11/2023 |
| Effect of variants in LGP2 on MDA5-mediated activation of interferon response and suppression of hepatitis D virus replication. | Effect of variants in LGP2 on MDA5-mediated activation of interferon response and suppression of hepatitis D virus replication.
Gillich N, Zhang Z, Binder M, Urban S, Bartenschlager R. | 12/31/2022 |
| Double-Stranded RNA Induces Mortality in an MDA5-Mediated Type I Interferonopathy Model. | Double-Stranded RNA Induces Mortality in an MDA5-Mediated Type I Interferonopathy Model.
Emralino FL, Satoh S, Sakai N, Takami M, Takeuchi F, Yan N, Rutsch F, Fujita T, Kato H. | 12/10/2022 |
| Direct Interaction of Coronavirus Nonstructural Protein 3 with Melanoma Differentiation-Associated Gene 5 Modulates Type I Interferon Response during Coronavirus Infection. | Direct Interaction of Coronavirus Nonstructural Protein 3 with Melanoma Differentiation-Associated Gene 5 Modulates Type I Interferon Response during Coronavirus Infection.
Sun X, Quan L, Chen R, Liu D., Free PMC Article | 10/22/2022 |
| Functional significance of the rare rs35667974 IFIH1 gene polymorphism, associated with multiple autoimmune diseases, using a structural biological approach. | Functional significance of the rare rs35667974 IFIH1 gene polymorphism, associated with multiple autoimmune diseases, using a structural biological approach.
Zervou MI, Andreou AC, Eliopoulos EE, Goulielmos GN. | 10/15/2022 |
| Intracellular virus sensor MDA5 mutation develops autoimmune myocarditis and nephritis. | Intracellular virus sensor MDA5 mutation develops autoimmune myocarditis and nephritis.
Ohto T, Tayeh AA, Nishikomori R, Abe H, Hashimoto K, Baba S, Arias-Loza AP, Soda N, Satoh S, Matsuda M, Iizuka Y, Kondo T, Koseki H, Yan N, Higuchi T, Fujita T, Kato H. | 03/26/2022 |
| Hepatic Macrophages Express Melanoma Differentiation-Associated Gene 5 in Nonalcoholic Steatohepatitis. | Hepatic Macrophages Express Melanoma Differentiation-Associated Gene 5 in Nonalcoholic Steatohepatitis.
Kawaguchi S, Sakuraba H, Horiuchi M, Ding J, Matsumiya T, Seya K, Iino C, Endo T, Kikuchi H, Yoshida S, Hiraga H, Fukuda S, Imaizumi T. | 03/26/2022 |
| Forced vital capacity predicts the survival of interstitial lung disease in anti-MDA5 positive dermatomyositis: a multi-centre cohort study. | Forced vital capacity predicts the survival of interstitial lung disease in anti-MDA5 positive dermatomyositis: a multi-centre cohort study.
Wu W, Xu W, Sun W, Zhang D, Zhao J, Luo Q, Wang X, Zhu F, Zheng Y, Xue Y, Wan W, Wu H, Han Q, Ye S. | 02/26/2022 |