| USP7 interacts with and destabilizes oncoprotein SET. | USP7 interacts with and destabilizes oncoprotein SET.
Chen J, Jiao Z, Liu Y, Zhang M, Wang D. | 04/30/2024 |
| Whole exome sequencing and transcriptome analysis in two unrelated patients with novel SET mutations. | Whole exome sequencing and transcriptome analysis in two unrelated patients with novel SET mutations.
Pan X, Liu S, Feng X, Liu L, Zhang X, Qian G, Liang N, Yao H, Dong X, Tan B. | 03/20/2024 |
| Oncoprotein SET-associated transcription factor ZBTB11 triggers lung cancer metastasis. | Oncoprotein SET-associated transcription factor ZBTB11 triggers lung cancer metastasis.
Xu W, Yao H, Wu Z, Yan X, Jiao Z, Liu Y, Zhang M, Wang D., Free PMC Article | 02/21/2024 |
| PP2A inhibitor SET promotes mTORC1 and Bmi1 signaling through Akt activation and maintains the colony-formation ability of cancer cells. | PP2A inhibitor SET promotes mTORC1 and Bmi1 signaling through Akt activation and maintains the colony-formation ability of cancer cells.
Kohyanagi N, Kitamura N, Ikeda S, Shibutani S, Sato K, Ohama T., Free PMC Article | 02/13/2024 |
| PP2A complex disruptor SET prompts widespread hypertranscription of growth-essential genes in the pancreatic cancer cells. | PP2A complex disruptor SET prompts widespread hypertranscription of growth-essential genes in the pancreatic cancer cells.
Xu H, Wu D, Xiao M, Lei Y, Lei Y, Yu X, Shi S., Free PMC Article | 02/4/2024 |
| HMGB1/SET/HAT1 complex-mediated SASH1 repression drives glycolysis and metastasis in lung adenocarcinoma. | HMGB1/SET/HAT1 complex-mediated SASH1 repression drives glycolysis and metastasis in lung adenocarcinoma.
Kou F, Wu L, Zheng Y, Yi Y, Ji Z, Huang Z, Guo S, Yang L. | 11/14/2023 |
| CBX8 Together with SET Facilitates Ovarian Carcinoma Growth and Metastasis by Suppressing the Transcription of SUSD2. | CBX8 Together with SET Facilitates Ovarian Carcinoma Growth and Metastasis by Suppressing the Transcription of SUSD2.
Wu Y, Duan Y, Li X, Zhao R, Lan B, Zhang X, Wang X, Chen H, Feng S, Liu Z, Cheng Y, Xi L, Wang Y, Xue F, Xuan C. | 11/12/2022 |
| Structural Mechanism of TAF-Ibeta Chaperone Function on Linker Histone H1.10. | Structural Mechanism of TAF-Iβ Chaperone Function on Linker Histone H1.10.
Feng H, Zhou BR, Schwieters CD, Bai Y., Free PMC Article | 10/1/2022 |
| The E3 Ligase TRIM4 Facilitates SET Ubiquitin-Mediated Degradation to Enhance ER-alpha Action in Breast Cancer. | The E3 Ligase TRIM4 Facilitates SET Ubiquitin-Mediated Degradation to Enhance ER-α Action in Breast Cancer.
Han D, Wang L, Long L, Su P, Luo D, Zhang H, Li Z, Chen B, Zhao W, Zhang N, Wang X, Liang Y, Li Y, Hu G, Yang Q., Free PMC Article | 09/17/2022 |
| The characteristics and prognostic significance of the SET-CAN/NUP214 fusion gene in hematological malignancies: A systematic review. | The characteristics and prognostic significance of the SET-CAN/NUP214 fusion gene in hematological malignancies: A systematic review.
Wang J, Zhan QR, Lu XX, Zhang LJ, Wang XX, Zhang HY., Free PMC Article | 08/13/2022 |
| Role of SET oncoprotein in hepatocellular carcinoma: An immunohistochemical study. | Role of SET oncoprotein in hepatocellular carcinoma: An immunohistochemical study.
Gadallah M, Asaad NY, Shabaan M, Elkholy SS, Samara MY, Taie D. | 07/2/2022 |
| The protein level of the tumour-promoting factor SET is regulated by cell density. | The protein level of the tumour-promoting factor SET is regulated by cell density.
Kohyanagi N, Kitamura N, Tanaka K, Mizuno T, Fujiwara N, Ohama T, Sato K. | 03/12/2022 |
| SET-NUP214 and MLL cooperatively regulate the promoter activity of the HoxA10 gene. | SET-NUP214 and MLL cooperatively regulate the promoter activity of the HoxA10 gene.
Cigdem S, Saito S, Nishikata D, Nagata K, Okuwaki M. | 01/29/2022 |
| Human TAF-Ialpha promotes oncogenic transformation via enhancement of cell proliferation and suppression of apoptosis. | Human TAF-Iα promotes oncogenic transformation via enhancement of cell proliferation and suppression of apoptosis.
Nenasheva VV, Makarova IV, Stepanenko EA, Antonov SA, Novosadova EV, Narsullaeva AR, Kozikova LV, Polteva EA, Sleptsova LA, Shcherbatova NA, Khaidarova NV, Andreeva LE, Tarantul VZ. | 12/25/2021 |
| SET levels contribute to cohesion fatigue. | SET levels contribute to cohesion fatigue.
Yang L, Zhang Q, Niu T, Liu H., Free PMC Article | 12/4/2021 |
| SET protein modulates H4 histone methylation status and regulates miR-137 level in oral squamous cell carcinoma. | SET protein modulates H4 histone methylation status and regulates miR-137 level in oral squamous cell carcinoma.
Sousa LO, Sobral LM, de Almeida LO, Garcia CB, Greene LJ, Leopoldino AM. | 08/14/2021 |
| SET nuclear proto-oncogene gene expression is associated with microsatellite instability in human colorectal cancer identified by co-expression analysis. | SET nuclear proto-oncogene gene expression is associated with microsatellite instability in human colorectal cancer identified by co-expression analysis.
Wang H, Qiu P, Zhu S, Zhang M, Li Y, Zhang M, Wang X, Shang J, Qu B, Liu J, Zhao Q. | 01/23/2021 |
| SET/TAF1 forms a distance-dependent feedback loop with Aurora B and Bub1 as a tension sensor at centromeres. | SET/TAF1 forms a distance-dependent feedback loop with Aurora B and Bub1 as a tension sensor at centromeres.
Asai Y, Matsumura R, Hasumi Y, Susumu H, Nagata K, Watanabe Y, Terada Y., Free PMC Article | 12/26/2020 |
| Phosphoproteome and drug-response effects mediated by the three protein phosphatase 2A inhibitor proteins CIP2A, SET, and PME-1. | Phosphoproteome and drug-response effects mediated by the three protein phosphatase 2A inhibitor proteins CIP2A, SET, and PME-1.
Kauko O, Imanishi SY, Kulesskiy E, Yetukuri L, Laajala TD, Sharma M, Pavic K, Aakula A, Rupp C, Jumppanen M, Haapaniemi P, Ruan L, Yadav B, Suni V, Varila T, Corthals GL, Reimand J, Wennerberg K, Aittokallio T, Westermarck J., Free PMC Article | 12/12/2020 |
| A new regulatory mechanism of protein phosphatase 2A activity via SET in acute myeloid leukemia. | A new regulatory mechanism of protein phosphatase 2A activity via SET in acute myeloid leukemia.
Arriazu E, Vicente C, Pippa R, Peris I, Martínez-Balsalobre E, García-Ramírez P, Marcotegui N, Igea A, Alignani D, Rifón J, Mateos MC, Cayuela ML, Nebreda AR, Odero MD., Free PMC Article | 09/26/2020 |
| a major function of SET during mitosis is to disrupt the Sgo1-cohesin interaction. | SET binding to Sgo1 inhibits Sgo1-cohesin interactions and promotes chromosome segregation.
Qu Q, Zhang Q, Yang L, Chen Y, Liu H., Free PMC Article | 05/23/2020 |
| It findings reveal the novel role of SET in fine-tuning the phosphorylation level at the kinetochore by balancing the activities of Aurora B and PP2A. | Aurora B kinase activity is regulated by SET/TAF1 on Sgo2 at the inner centromere.
Asai Y, Fukuchi K, Tanno Y, Koitabashi-Kiyozuka S, Kiyozuka T, Noda Y, Matsumura R, Koizumi T, Watanabe A, Nagata K, Watanabe Y, Terada Y., Free PMC Article | 05/16/2020 |
| Findings indicate that p53 activity is inhibited by I2PP2A upstream of PP2A in SHH-activated and TP53-wildtype medulloblastomas. | p53 Function Is Compromised by Inhibitor 2 of Phosphatase 2A in Sonic Hedgehog Medulloblastoma.
Wei Y, Maximov V, Morrissy SA, Taylor MD, Pallas DC, Kenney AM., Free PMC Article | 01/25/2020 |
| These findings indicate that alternative splicing of SET, and potentially other signalling cascade molecules, influences CLL biology and patient outcomes. | SET alpha and SET beta mRNA isoforms in chronic lymphocytic leukaemia.
Brander DM, Friedman DR, Volkheimer AD, Christensen DJ, Rassenti LZ, Kipps TJ, Guadalupe E, Chen Y, Zhang D, Wang X, Davis C, Owzar K, Weinberg JB., Free PMC Article | 12/28/2019 |
| Authors suggest that SET/TAF-Ialpha might be a tumor suppressing factor regulated by miR-21-5p in lung adenocarcinoma. | miR-21-5p promotes lung adenocarcinoma progression partially through targeting SET/TAF-Iα.
Zhong J, Ren X, Chen Z, Zhang H, Zhou L, Yuan J, Li P, Chen X, Liu W, Wu D, Yang X, Liu J. | 09/21/2019 |