| Secreted frizzled-related protein 5 overexpression reverses oxLDL-induced lipid accumulation in human vascular smooth muscle cells. | Secreted frizzled-related protein 5 overexpression reverses oxLDL-induced lipid accumulation in human vascular smooth muscle cells.
Wang X, Chen S, Yu C, Lu R, Sun Y, Guan Z, Gao Y. | 06/30/2024 |
| SFRP5 Partially Inhibits the Proliferation and Migration of Airway Smooth Muscle Cells in Children with Asthma by Regulating the Wnt/beta-Catenin Signaling Pathway. | SFRP5 Partially Inhibits the Proliferation and Migration of Airway Smooth Muscle Cells in Children with Asthma by Regulating the Wnt/β-Catenin Signaling Pathway.
Yuan Y, Zhu H, Huang S, Zhang Y, Shen Y. | 02/29/2024 |
| TFAP2C inhibits cell autophagy to alleviate myocardial ischemia/reperfusion injury by regulating miR-23a-5p/SFRP5/Wnt5a axis. | TFAP2C inhibits cell autophagy to alleviate myocardial ischemia/reperfusion injury by regulating miR-23a-5p/SFRP5/Wnt5a axis.
Zeng M, Wei X, He YL, Chen JX, Lin WT. | 05/19/2023 |
| Frizzled receptors and SFRP5 in lipid metabolism: Current findings and potential applications. | Frizzled receptors and SFRP5 in lipid metabolism: Current findings and potential applications.
Chu DT, Nguyen TL. | 02/10/2023 |
| Increased Secreted Frizzled-Related Protein 5 mRNA Expression in the Adipose Tissue of Women with Nonalcoholic Fatty Liver Disease Associated with Obesity. | Increased Secreted Frizzled-Related Protein 5 mRNA Expression in the Adipose Tissue of Women with Nonalcoholic Fatty Liver Disease Associated with Obesity.
Bertran L, Portillo-Carrasquer M, Barrientos-Riosalido A, Aguilar C, Riesco D, Martínez S, Culebradas A, Vives M, Sabench F, Castillo DD, Richart C, Auguet T., Free PMC Article | 10/1/2022 |
| Circulating level of serum secreted frizzled-related protein 5 decreases in polycystic ovary syndrome. | Circulating level of serum secreted frizzled-related protein 5 decreases in polycystic ovary syndrome.
Tasgoz FN, Kender Erturk N, Temur M. | 07/23/2022 |
| The role of Wnt pathway antagonists in early-stage lung adenocarcinoma. | The role of Wnt pathway antagonists in early-stage lung adenocarcinoma.
Zeybek A, Öz N, Kalemci S, Tosun K, Edgünlü TG, Kızıltuğ MT, Tekin L, Erdal ME. | 03/26/2022 |
| Elevated Serum SFRP5 Levels During Preeclampsia and Its Potential Association with Trophoblast Dysfunction via Wnt/beta-Catenin Suppression. | Elevated Serum SFRP5 Levels During Preeclampsia and Its Potential Association with Trophoblast Dysfunction via Wnt/β-Catenin Suppression.
Zhang Y, Ran Y, Ma Y, Huang H, Chen Y, Qi H. | 03/12/2022 |
| Decreased SFRP5 correlated with excessive metabolic inflammation in polycystic ovary syndrome could be reversed by metformin: implication of its role in dysregulated metabolism. | Decreased SFRP5 correlated with excessive metabolic inflammation in polycystic ovary syndrome could be reversed by metformin: implication of its role in dysregulated metabolism.
Zhang Y, Ran Y, Kong L, Geng L, Huang H, Zhang H, Hu J, Qi H, Chen Y., Free PMC Article | 01/29/2022 |
| PPARgamma attenuates hepatic inflammation and oxidative stress of nonalcoholic steatohepatitis via modulating the miR215p/SFRP5 pathway. | PPARγ attenuates hepatic inflammation and oxidative stress of non‑alcoholic steatohepatitis via modulating the miR‑21‑5p/SFRP5 pathway.
Zhang X, Deng F, Zhang Y, Zhang X, Chen J, Jiang Y., Free PMC Article | 01/22/2022 |
| Serum secreted frizzled-related protein 5 in relation to insulin sensitivity and its regulation by insulin and free fatty acids. | Serum secreted frizzled-related protein 5 in relation to insulin sensitivity and its regulation by insulin and free fatty acids.
Rydzewska M, Nikołajuk A, Matulewicz N, Stefanowicz M, Karczewska-Kupczewska M., Free PMC Article | 10/30/2021 |
| SFRP5 Enhances Wnt5a Induced-Inflammation in Rheumatoid Arthritis Fibroblast-Like Synoviocytes. | SFRP5 Enhances Wnt5a Induced-Inflammation in Rheumatoid Arthritis Fibroblast-Like Synoviocytes.
Mahmoud DE, Kaabachi W, Sassi N, Mokhtar A, Moalla M, Ammar LB, Jemmali S, Rekik S, Tarhouni L, Kallel-Sellami M, Cheour E, Laadhar L., Free PMC Article | 10/23/2021 |
| The Emerging Role of Sfrp5 and Wnt5a in the Pathogenesis of Obesity: Implications for a Healthy Diet and Lifestyle. | The Emerging Role of Sfrp5 and Wnt5a in the Pathogenesis of Obesity: Implications for a Healthy Diet and Lifestyle.
Koutaki D, Michos A, Bacopoulou F, Charmandari E., Free PMC Article | 09/4/2021 |
| High preoperative levels of circulating SFRP5 predict better prognosis in colorectal cancer patients. | High preoperative levels of circulating SFRP5 predict better prognosis in colorectal cancer patients.
Kirana C, Smith E, Ngo DT, Trochsler MI, Hewett PJ, Stubbs RS, Hardingham JE, Maddern GJ, Hauben E. | 07/17/2021 |
| Sfrp5/Wnt5a and leptin/adiponectin levels in the serum and the periarterial adipose tissue of patients with peripheral arterial occlusive disease. | Sfrp5/Wnt5a and leptin/adiponectin levels in the serum and the periarterial adipose tissue of patients with peripheral arterial occlusive disease.
Wang B, Pan Y, Yang G, Cui Z, Yu W, Liu H, Bai B. | 05/29/2021 |
| The regulatory role of SFRP5/WNT5A axis in allergic rhinitis through inhibiting JNK pathway activation and lowering mucin generation in human nasal epithelial cells. | The regulatory role of SFRP5/WNT5A axis in allergic rhinitis through inhibiting JNK pathway activation and lowering mucin generation in human nasal epithelial cells.
Shi Z, Xu M, Chen X, Wang J, Zhao T, Zha D. | 05/1/2021 |
| SFRP5 mediates downregulation of the wnt5a/caveolin-1/JNK signaling pathway. | SFRP5 mediates downregulation of the wnt5a/caveolin-1/JNK signaling pathway.
Liu W, Ji Y, Chu H, Wang M, Yang B, Yin C. | 02/20/2021 |
| Circ_LAS1L regulates cardiac fibroblast activation, growth, and migration through miR-125b/SFRP5 pathway. | Circ_LAS1L regulates cardiac fibroblast activation, growth, and migration through miR-125b/SFRP5 pathway.
Sun LY, Zhao JC, Ge XM, Zhang H, Wang CM, Bie ZD. | 01/9/2021 |
| SFRP5 overexpression suppresses the aggressive phenotype of prostate cancer cells and overcomes docetaxel resistance through inactivation of beta-catenin signaling. | Secreted frizzled-related protein 5 suppresses aggressive phenotype and reverses docetaxel resistance in prostate cancer.
Xu Q, Lü Z, Wang X, Zhu Q, Wu H. | 07/18/2020 |
| The Secreted frizzled-related protein (Sfrp)-5, an antagonist that directly binds to Wnt, has attracted interest due to its favorable effects on atherosclerotic cardiovascular disease (ASCVD). | Sfrp5/Wnt Pathway: A Protective Regulatory System in Atherosclerotic Cardiovascular Disease.
Tong S, Ji Q, Du Y, Zhu X, Zhu C, Zhou Y., Free PMC Article | 07/11/2020 |
| Slurp1 regulate the synthesis pathway of Triglycerides through Sfrp5 in hepatocyte steatosis model. | Sfrp5 interacts with Slurp1 to regulate the accumulation of triglycerides in hepatocyte steatosis model.
Zhao A, Jiang F, Yang G, Liu H, Li L. | 02/8/2020 |
| Results identified and confirmed to have downregulated gene expression of SFRP5 in sporadic nonfunctioning pancreatic neuroendocrine tumors (NFPanNETs) and CDCA7L and RBM47 in MEN1-related NFPanNETs. | Distinct genome-wide methylation patterns in sporadic and hereditary nonfunctioning pancreatic neuroendocrine tumors.
Tirosh A, Mukherjee S, Lack J, Gara SK, Wang S, Quezado MM, Keutgen XM, Wu X, Cam M, Kumar S, Patel D, Nilubol N, Tyagi MV, Kebebew E., Free PMC Article | 01/18/2020 |
| Sfrp5 was significantly positively related to BUN. | Circulating secreted frizzled-related protein 5 and chronic kidney disease in patients with acute ST-segment elevation myocardial infarction.
Wang CP, Yu TH, Wu CC, Hung WC, Hsu CC, Tsai IT, Tang WH, Chung FM, Houng JY, Lee YJ, Lu YC. | 10/26/2019 |
| Identify SFRP5 as a novel vasodilative adipokine that induces endothelial NO production by antagonizing the WNT5A/JNK signaling pathway. Elevated serum SFRP5 concentration was significantly associated with arterial stiffness in human subjects with type 2 diabetes mellitus. | Effect of SFRP5 (Secreted Frizzled-Related Protein 5) on the WNT5A (Wingless-Type Family Member 5A)-Induced Endothelial Dysfunction and Its Relevance With Arterial Stiffness in Human Subjects.
Cho YK, Kang YM, Lee SE, Lee Y, Seol SM, Lee WJ, Park JY, Jung CH. | 07/13/2019 |
| excessive gestational weight gain is associated with disturbances in SFRP5 concentrations. | Umbilical Cord SFRP5 Levels of Term Newborns in Relation to Normal and Excessive Gestational Weight Gain.
Kimber-Trojnar Ż, Patro-Małysza J, Trojnar M, Darmochwał-Kolarz D, Oleszczuk J, Leszczyńska-Gorzelak B., Free PMC Article | 05/18/2019 |