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    SRSF1 serine and arginine rich splicing factor 1 [ Homo sapiens (human) ]

    Gene ID: 6426, updated on 5-May-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Circ_0001786 facilitates gefitinib resistance and malignant progression in non-small cell lung cancer via miR-34b-5p/SRSF1.

    Circ_0001786 facilitates gefitinib resistance and malignant progression in non-small cell lung cancer via miR-34b-5p/SRSF1.
    Ouyang K, Xie D, Liao H, He Y, Xiong H., Free PMC Article

    04/16/2024
    TIM22 and TIM29 inhibit HBV replication by up-regulating SRSF1 expression.

    TIM22 and TIM29 inhibit HBV replication by up-regulating SRSF1 expression.
    Guo L, Liu JJ, Long SY, Wang PY, Li S, Wang JL, Wei XF, Li J, Lei L, Huang AL, Hu JL.

    02/5/2024
    Splicing Factor SRSF1 Promotes Pancreatitis and KRASG12D-Mediated Pancreatic Cancer.

    Splicing Factor SRSF1 Promotes Pancreatitis and KRASG12D-Mediated Pancreatic Cancer.
    Wan L, Lin KT, Rahman MA, Ishigami Y, Wang Z, Jensen MA, Wilkinson JE, Park Y, Tuveson DA, Krainer AR., Free PMC Article

    07/12/2023
    SRSF1 haploinsufficiency is responsible for a syndromic developmental disorder associated with intellectual disability.

    SRSF1 haploinsufficiency is responsible for a syndromic developmental disorder associated with intellectual disability.
    Bogaert E, Garde A, Gautier T, Rooney K, Duffourd Y, LeBlanc P, van Reempts E, Tran Mau-Them F, Wentzensen IM, Au KS, Richardson K, Northrup H, Gatinois V, Geneviève D, Louie RJ, Lyons MJ, Laulund LW, Brasch-Andersen C, Maxel Juul T, El It F, Marle N, Callier P, Relator R, Haghshenas S, McConkey H, Kerkhof J, Cesario C, Novelli A, Brunetti-Pierri N, Pinelli M, Pennamen P, Naudion S, Legendre M, Courdier C, Trimouille A, Fenzy MD, Pais L, Yeung A, Nugent K, Roeder ER, Mitani T, Posey JE, Calame D, Yonath H, Rosenfeld JA, Musante L, Faletra F, Montanari F, Sartor G, Vancini A, Seri M, Besmond C, Poirier K, Hubert L, Hemelsoet D, Munnich A, Lupski JR, Philippe C, Thauvin-Robinet C, Faivre L, Sadikovic B, Govin J, Dermaut B, Vitobello A., Free PMC Article

    05/9/2023
    New association between splicing factor-coding gene polymorphisms and the risk of acute lymphoblastic leukemia in southern Chinese children: A five-center case-control study.

    New association between splicing factor-coding gene polymorphisms and the risk of acute lymphoblastic leukemia in southern Chinese children: A five-center case-control study.
    Deng D, Luo A, Li M, Yan Y, Cai M, Liu S, Liu X, Wang X, Zhang X, Jiang H, Liu X.

    04/5/2023
    Splicing factor SRSF1 deficiency in the liver triggers NASH-like pathology and cell death.

    Splicing factor SRSF1 deficiency in the liver triggers NASH-like pathology and cell death.
    Arif W, Mathur B, Saikali MF, Chembazhi UV, Toohill K, Song YJ, Hao Q, Karimi S, Blue SM, Yee BA, Van Nostrand EL, Bangru S, Guzman G, Yeo GW, Prasanth KV, Anakk S, Cummins CL, Kalsotra A., Free PMC Article

    02/15/2023
    CircCDR1as mediates PM2.5-induced lung cancer progression by binding to SRSF1.

    CircCDR1as mediates PM(2.5)-induced lung cancer progression by binding to SRSF1.
    Xu J, Huang L, Bao T, Duan K, Cheng Y, Zhang H, Zhang Y, Li J, Li Q, Li F.

    02/4/2023
    Inter-domain Flexibility of Human Ser/Arg-Rich Splicing Factor 1 Allows Variable Spacer Length in Cognate RNA's Bipartite Motifs.

    Inter-domain Flexibility of Human Ser/Arg-Rich Splicing Factor 1 Allows Variable Spacer Length in Cognate RNA's Bipartite Motifs.
    De Silva NIU, Fargason T, Zhang Z, Wang T, Zhang J.

    12/31/2022
    SRSF1 acts as an IFN-I-regulated cellular dependency factor decisively affecting HIV-1 post-integration steps.

    SRSF1 acts as an IFN-I-regulated cellular dependency factor decisively affecting HIV-1 post-integration steps.
    Sertznig H, Roesmann F, Wilhelm A, Heininger D, Bleekmann B, Elsner C, Santiago M, Schuhenn J, Karakoese Z, Benatzy Y, Snodgrass R, Esser S, Sutter K, Dittmer U, Widera M., Free PMC Article

    12/10/2022
    Circ_000829 Plays an Anticancer Role in Renal Cell Carcinoma by Suppressing SRSF1-Mediated Alternative Splicing of SLC39A14.

    Circ_000829 Plays an Anticancer Role in Renal Cell Carcinoma by Suppressing SRSF1-Mediated Alternative Splicing of SLC39A14.
    Feng JF, Yang WY, Wang YD, Xie G, Xu B, Dai CM, Zhang B, Li XH, Wang J, Yang YW., Free PMC Article

    09/10/2022
    Emergent Role of IFITM1/3 towards Splicing Factor (SRSF1) and Antigen-Presenting Molecule (HLA-B) in Cervical Cancer.

    Emergent Role of IFITM1/3 towards Splicing Factor (SRSF1) and Antigen-Presenting Molecule (HLA-B) in Cervical Cancer.
    Gómez-Herranz M, Faktor J, Yébenes Mayordomo M, Pilch M, Nekulova M, Hernychova L, Ball KL, Vojtesek B, Hupp TR, Kote S., Free PMC Article

    09/3/2022
    VEGF gene polymorphisms regulate human retinal vascular endothelial cell proliferation and apoptosis through ASF/SF2-associated alternative splicing.

    VEGF gene polymorphisms regulate human retinal vascular endothelial cell proliferation and apoptosis through ASF/SF2-associated alternative splicing.
    Li H, Xie J, Zeng J, Wu J, Zhou J, Zhao W.

    08/20/2022
    Serine and arginine rich splicing factor 1 deficiency alters pathways involved in IL-17A expression and is implicated in human psoriasis.

    Serine and arginine rich splicing factor 1 deficiency alters pathways involved in IL-17A expression and is implicated in human psoriasis.
    Su S, Katopodi XL, Pita-Juarez YH, Maverakis E, Vlachos IS, Adamopoulos IE., Free PMC Article

    06/18/2022
    The long non-coding RNA PFI protects against pulmonary fibrosis by interacting with splicing regulator SRSF1.

    The long non-coding RNA PFI protects against pulmonary fibrosis by interacting with splicing regulator SRSF1.
    Sun J, Jin T, Su W, Guo Y, Niu Z, Guo J, Li L, Wang J, Ma L, Yu T, Li X, Zhou Y, Shan H, Liang H., Free PMC Article

    03/26/2022
    SRSF1 inhibits autophagy through regulating Bcl-x splicing and interacting with PIK3C3 in lung cancer.

    SRSF1 inhibits autophagy through regulating Bcl-x splicing and interacting with PIK3C3 in lung cancer.
    Lv Y, Zhang W, Zhao J, Sun B, Qi Y, Ji H, Chen C, Zhang J, Sheng J, Wang T, Dominguez D, Liu H, Liu Q, Meng S, Li X, Wang Y., Free PMC Article

    03/12/2022
    SRSF-1 and microvessel density immunohistochemical analysis by semi-automated tissue microarray in prostate cancer patients with diabetes (DIAMOND study).

    SRSF-1 and microvessel density immunohistochemical analysis by semi-automated tissue microarray in prostate cancer patients with diabetes (DIAMOND study).
    Broggi G, Lo Giudice A, Di Mauro M, Asmundo MG, Pricoco E, Piombino E, Caltabiano R, Morgia G, Russo GI., Free PMC Article

    02/19/2022
    Extracellular matrix stiffness controls VEGF165 secretion and neuroblastoma angiogenesis via the YAP/RUNX2/SRSF1 axis.

    Extracellular matrix stiffness controls VEGF(165) secretion and neuroblastoma angiogenesis via the YAP/RUNX2/SRSF1 axis.
    Bao M, Chen Y, Liu JT, Bao H, Wang WB, Qi YX, Lv F.

    02/19/2022
    The Immunohistochemical Expression of the Serine and Arginine-Rich Splicing Factor 1 (SRSF1) Is a Predictive Factor of the Recurrence of Basal Cell Carcinoma: A Preliminary Study on a Series of 52 Cases.

    The Immunohistochemical Expression of the Serine and Arginine-Rich Splicing Factor 1 (SRSF1) Is a Predictive Factor of the Recurrence of Basal Cell Carcinoma: A Preliminary Study on a Series of 52 Cases.
    Broggi G, Barbagallo D, Lacarrubba F, Verzì AE, Micali G, Purrello M, Caltabiano R., Free PMC Article

    01/29/2022
    Exon-independent recruitment of SRSF1 is mediated by U1 snRNP stem-loop 3.

    Exon-independent recruitment of SRSF1 is mediated by U1 snRNP stem-loop 3.
    Jobbins AM, Campagne S, Weinmeister R, Lucas CM, Gosliga AR, Clery A, Chen L, Eperon LP, Hodson MJ, Hudson AJ, Allain FHT, Eperon IC., Free PMC Article

    01/15/2022
    A splicing factor phosphorylated by protein kinase A is increased in HL60 cells treated with retinoic acid.

    A splicing factor phosphorylated by protein kinase A is increased in HL60 cells treated with retinoic acid.
    Saito D, Imai M, Hasegawa S, Yamasaki M, Takahashi N.

    01/1/2022
    Splicing factor SRSF1 promotes breast cancer progression via oncogenic splice switching of PTPMT1.

    Splicing factor SRSF1 promotes breast cancer progression via oncogenic splice switching of PTPMT1.
    Du JX, Luo YH, Zhang SJ, Wang B, Chen C, Zhu GQ, Zhu P, Cai CZ, Wan JL, Cai JL, Chen SP, Dai Z, Zhu W., Free PMC Article

    12/25/2021
    RNA binding protein serine/arginine splicing factor 1 promotes the proliferation, migration and invasion of hepatocellular carcinoma by interacting with RecQ protein-like 4 mRNA.

    RNA binding protein serine/arginine splicing factor 1 promotes the proliferation, migration and invasion of hepatocellular carcinoma by interacting with RecQ protein-like 4 mRNA.
    Ye Y, Yu F, Li Z, Xie Y, Yu X., Free PMC Article

    12/18/2021
    A behavioral screen for mediators of age-dependent TDP-43 neurodegeneration identifies SF2/SRSF1 among a group of potent suppressors in both neurons and glia.

    A behavioral screen for mediators of age-dependent TDP-43 neurodegeneration identifies SF2/SRSF1 among a group of potent suppressors in both neurons and glia.
    Azpurua J, El-Karim EG, Tranquille M, Dubnau J., Free PMC Article

    12/4/2021
    Long noncoding RNA DGCR5 involves in tumorigenesis of esophageal squamous cell carcinoma via SRSF1-mediated alternative splicing of Mcl-1.

    Long noncoding RNA DGCR5 involves in tumorigenesis of esophageal squamous cell carcinoma via SRSF1-mediated alternative splicing of Mcl-1.
    Duan Y, Jia Y, Wang J, Liu T, Cheng Z, Sang M, Lv W, Qin J, Liu L., Free PMC Article

    11/6/2021
    lncRNA LINC01296 Promotes Oral Squamous Cell Carcinoma Development by Binding with SRSF1.

    lncRNA LINC01296 Promotes Oral Squamous Cell Carcinoma Development by Binding with SRSF1.
    Zhang Y, Wang A, Zhang X, Wang X, Zhang J, Ma J., Free PMC Article

    10/30/2021
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