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    CXCR5 C-X-C motif chemokine receptor 5 [ Homo sapiens (human) ]

    Gene ID: 643, updated on 2-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    CXCR5 Regulates Neuronal Polarity Development and Migration in the Embryonic Stage via F-Actin Homeostasis and Results in Epilepsy-Related Behavior.

    CXCR5 Regulates Neuronal Polarity Development and Migration in the Embryonic Stage via F-Actin Homeostasis and Results in Epilepsy-Related Behavior.
    Zhang Z, Zhang H, Antonic-Baker A, Kwan P, Yan Y, Ma Y., Free PMC Article

    10/28/2023
    CCR9/CXCR5 Co-Expressing CD4 T Cells Are Increased in Primary Sjogren's Syndrome and Are Enriched in PD-1/ICOS-Expressing Effector T Cells.

    CCR9/CXCR5 Co-Expressing CD4 T Cells Are Increased in Primary Sjögren's Syndrome and Are Enriched in PD-1/ICOS-Expressing Effector T Cells.
    Hinrichs AC, Kruize AA, Lafeber FPJG, Leavis HL, van Roon JAG., Free PMC Article

    08/19/2023
    Circulating DNA methylation level of CXCR5 correlates with inflammation in patients with rheumatoid arthritis.

    Circulating DNA methylation level of CXCR5 correlates with inflammation in patients with rheumatoid arthritis.
    Shi Y, Chang C, Xu L, Jiang P, Wei K, Zhao J, Xu L, Jin Y, Zhang R, Wang H, Qian Y, Qin Y, Ding Q, Jiang T, Guo S, Wang R, He D., Free PMC Article

    07/7/2023
    Heterogeneity of circulating CXCR5-PD-1[hi]Tph cells in patients of type 2 and type 1 diabetes in Chinese population.

    Heterogeneity of circulating CXCR5-PD-1(hi)Tph cells in patients of type 2 and type 1 diabetes in Chinese population.
    Su Z, Ma C, Zhao R, Jiang Y, Cai Y, Yong G, Yang T, Xu X.

    05/10/2023
    Several genetic variants associated with systemic sclerosis in a Chinese Han population.

    Several genetic variants associated with systemic sclerosis in a Chinese Han population.
    Liu C, Yan S, Chen H, Wu Z, Li L, Li Y.

    02/22/2023
    Characterization of C-X-C chemokine receptor type 5 in the cornea and role in the inflammatory response after corneal injury.

    Characterization of C-X-C chemokine receptor type 5 in the cornea and role in the inflammatory response after corneal injury.
    Balne PK, Gupta S, Landon KM, Sinha NR, Hofmann AC, Hauser N, Sinha PR, Huang H, Kempuraj D, Mohan RR.

    01/14/2023
    In patients with primary Sjogren's syndrome innate-like MAIT cells display upregulated IL-7R, IFN-gamma, and IL-21 expression and have increased proportions of CCR9 and CXCR5-expressing cells.

    In patients with primary Sjögren's syndrome innate-like MAIT cells display upregulated IL-7R, IFN-γ, and IL-21 expression and have increased proportions of CCR9 and CXCR5-expressing cells.
    Hinrichs AC, Kruize AA, Leavis HL, van Roon JAG., Free PMC Article

    01/11/2023
    Association of Gene Polymorphisms in CXC Chemokine Receptor 5 with Rheumatoid Arthritis Susceptibility.

    Association of Gene Polymorphisms in CXC Chemokine Receptor 5 with Rheumatoid Arthritis Susceptibility.
    Su Z, Chen L, Niu Q, Yang B, Huang Z.

    11/12/2022
    CXCR5/CXCL13 pathway, a key driver for migration of regulatory B10 cells, is defective in patients with rheumatoid arthritis.

    CXCR5/CXCL13 pathway, a key driver for migration of regulatory B10 cells, is defective in patients with rheumatoid arthritis.
    Rempenault C, Mielle J, Schreiber K, Corbeau P, Macia L, Combe B, Morel J, Daien CI, Audo R.

    05/14/2022
    Hypermethylation at the CXCR5 gene locus limits trafficking potential of CD8+ T cells into B-cell follicles during HIV-1 infection.

    Hypermethylation at the CXCR5 gene locus limits trafficking potential of CD8+ T cells into B-cell follicles during HIV-1 infection.
    Ogunshola FJ, Smidt W, Naidoo AF, Nkosi T, Ngubane T, Khaba T, Baiyegunhi OO, Mahlobo B, Rasehlo S, Ngema N, Jajbhay I, Dong KL, Ramsuran V, Pansegrouw J, Ndung'u T, Walker BD, Oliveria T, Ndhlovu ZM., Free PMC Article

    04/9/2022
    Targeting Erbin in B cells for therapy of lung metastasis of colorectal cancer.

    Targeting Erbin in B cells for therapy of lung metastasis of colorectal cancer.
    Shen T, Liu JL, Wang CY, Rixiati Y, Li S, Cai LD, Zhao YY, Li JM., Free PMC Article

    03/12/2022
    CXC chemokine ligand-13 promotes metastasis via CXCR5-dependent signaling pathway in non-small cell lung cancer.

    CXC chemokine ligand-13 promotes metastasis via CXCR5-dependent signaling pathway in non-small cell lung cancer.
    Chao CC, Lee WF, Wang SW, Chen PC, Yamamoto A, Chang TM, Weng SL, Liu JF., Free PMC Article

    02/19/2022
    CXCL13/CXCR5 axis facilitates endothelial progenitor cell homing and angiogenesis during rheumatoid arthritis progression.

    CXCL13/CXCR5 axis facilitates endothelial progenitor cell homing and angiogenesis during rheumatoid arthritis progression.
    Tsai CH, Chen CJ, Gong CL, Liu SC, Chen PC, Huang CC, Hu SL, Wang SW, Tang CH., Free PMC Article

    01/29/2022
    The CXCL13/CXCR5-chemokine axis in neuroinflammation: evidence of CXCR5+CD4 T cell recruitment to CSF.

    The CXCL13/CXCR5-chemokine axis in neuroinflammation: evidence of CXCR5+CD4 T cell recruitment to CSF.
    Harrer C, Otto F, Pilz G, Haschke-Becher E, Trinka E, Hitzl W, Wipfler P, Harrer A., Free PMC Article

    01/29/2022
    ETV4 promotes pancreatic ductal adenocarcinoma metastasis through activation of the CXCL13/CXCR5 signaling axis.

    ETV4 promotes pancreatic ductal adenocarcinoma metastasis through activation of the CXCL13/CXCR5 signaling axis.
    Gao X, Jiang M, Chu Y, Han Y, Jin Y, Zhang W, Wang W, Yang S, Li W, Fan A, Cao J, Wang J, Liu H, Fu X, Chen D, Nie Y, Fan D.

    01/8/2022
    CXCL13 shapes immunoactive tumor microenvironment and enhances the efficacy of PD-1 checkpoint blockade in high-grade serous ovarian cancer.

    CXCL13 shapes immunoactive tumor microenvironment and enhances the efficacy of PD-1 checkpoint blockade in high-grade serous ovarian cancer.
    Yang M, Lu J, Zhang G, Wang Y, He M, Xu Q, Xu C, Liu H., Free PMC Article

    12/18/2021
    Simulating CXCR5 Dynamics in Complex Tissue Microenvironments.

    Simulating CXCR5 Dynamics in Complex Tissue Microenvironments.
    Cosgrove J, Alden K, Stein JV, Coles MC, Timmis J., Free PMC Article

    12/18/2021
    CXC Chemokine Receptor Type 5 Gene Polymorphisms in a Cohort of Egyptian Patients with Diffuse Large B-Cell Lymphoma.

    CXC Chemokine Receptor Type 5 Gene Polymorphisms in a Cohort of Egyptian Patients with Diffuse Large B-Cell Lymphoma.
    Makhlouf MM, Radwan ER, Khorshed OM, Fathi LM, Elmasry MM.

    10/16/2021
    CXCL13/CXCR5 signalling is pivotal to preserve motor neurons in amyotrophic lateral sclerosis.

    CXCL13/CXCR5 signalling is pivotal to preserve motor neurons in amyotrophic lateral sclerosis.
    Trolese MC, Mariani A, Terao M, de Paola M, Fabbrizio P, Sironi F, Kurosaki M, Bonanno S, Marcuzzo S, Bernasconi P, Trojsi F, Aronica E, Bendotti C, Nardo G., Free PMC Article

    08/28/2021
    Human CXCR5(+) PD-1(+) CD8 T cells in healthy individuals and patients with hematologic malignancies.

    Human CXCR5(+) PD-1(+) CD8 T cells in healthy individuals and patients with hematologic malignancies.
    Hofland T, Martens AWJ, van Bruggen JAC, de Boer R, Schetters S, Remmerswaal EBM, Bemelman FJ, Levin MD, Bins AD, Eldering E, Kater AP, Tonino SH., Free PMC Article

    08/21/2021
    Correlation between CXCR4, CXCR5 and CCR7 expression and survival outcomes in patients with clinical T1N0M0 non-small cell lung cancer.

    Correlation between CXCR4, CXCR5 and CCR7 expression and survival outcomes in patients with clinical T1N0M0 non-small cell lung cancer.
    Yue Z, Ningning D, Lin Y, Jianming Y, Hongtu Z, Ligong Y, Feng L, Shuaibo W, Yousheng M., Free PMC Article

    08/14/2021
    CXCR5 induces perineural invasion of salivary adenoid cystic carcinoma by inhibiting microRNA-187.

    CXCR5 induces perineural invasion of salivary adenoid cystic carcinoma by inhibiting microRNA-187.
    Zhang M, Wu JS, Xian HC, Chen BJ, Wang HF, Yu XH, Pang X, Dai L, Jiang J, Liang XH, Tang YL., Free PMC Article

    07/24/2021
    Long noncoding RNA PLK1S1 was associated with renal cell carcinoma progression by interacting with microRNA653 and altering CXC chemokine receptor 5 expression.

    Long non‑coding RNA PLK1S1 was associated with renal cell carcinoma progression by interacting with microRNA‑653 and altering C‑X‑C chemokine receptor 5 expression.
    Li W, Yang D, Zhang Y, Zhao S, Li D, Liu M., Free PMC Article

    07/10/2021
    Cytotoxic CD8+ T Cells Expressing CXCR5 Are Detectable in HIV-1 Elite Controllers After Prolonged In Vitro Peptide Stimulation.

    Cytotoxic CD8+ T Cells Expressing CXCR5 Are Detectable in HIV-1 Elite Controllers After Prolonged In Vitro Peptide Stimulation.
    Adams P, Iserentant G, Servais JY, Vandekerckhove L, Vanham G, Seguin-Devaux C, PhenoCure Study Group., Free PMC Article

    06/26/2021
    Possible roles of CXCL13/CXCR5 axis in the development of bullous pemphigoid.

    Possible roles of CXCL13/CXCR5 axis in the development of bullous pemphigoid.
    Ohuchi K, Fujimura T, Lyu C, Amagai R, Muto Y, Aiba S.

    06/26/2021
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