Impact of Sonic Hedgehog-dependent sphenoid bone defect on craniofacial growth. | Impact of Sonic Hedgehog-dependent sphenoid bone defect on craniofacial growth. Guyodo H, Rizzo A, Diab F, Noury F, Mironov S, de Tayrac M, David V, Odent S, Dubourg C, Dupé V., Free PMC Article | 04/4/2024 |
SALL4 is a CRL3[REN/KCTD11] substrate that drives Sonic Hedgehog-dependent medulloblastoma. | SALL4 is a CRL3(REN/KCTD11) substrate that drives Sonic Hedgehog-dependent medulloblastoma. Lospinoso Severini L, Loricchio E, Navacci S, Basili I, Alfonsi R, Bernardi F, Moretti M, Conenna M, Cucinotta A, Coni S, Petroni M, De Smaele E, Giannini G, Maroder M, Canettieri G, Mastronuzzi A, Guardavaccaro D, Ayrault O, Infante P, Bufalieri F, Di Marcotullio L., Free PMC Article | 02/12/2024 |
Tumor Explants Elucidate a Cascade of Paracrine SHH, WNT, and VEGF Signals Driving Pancreatic Cancer Angiosuppression. | Tumor Explants Elucidate a Cascade of Paracrine SHH, WNT, and VEGF Signals Driving Pancreatic Cancer Angiosuppression. Hasselluhn MC, Decker-Farrell AR, Vlahos L, Thomas DH, Curiel-Garcia A, Maurer HC, Wasko UN, Tomassoni L, Sastra SA, Palermo CF, Dalton TC, Ma A, Li F, Tolosa EJ, Hibshoosh H, Fernandez-Zapico ME, Muir A, Califano A, Olive KP., Free PMC Article | 02/12/2024 |
Phosphorylation of human glioma-associated oncogene 1 on Ser937 regulates Sonic Hedgehog signaling in medulloblastoma. | Phosphorylation of human glioma-associated oncogene 1 on Ser937 regulates Sonic Hedgehog signaling in medulloblastoma. Zeng LH, Tang C, Yao M, He Q, Qv M, Ren Q, Xu Y, Shen T, Gu W, Xu C, Zou C, Ji X, Wu X, Wang J., Free PMC Article | 02/7/2024 |
Serum levels of sonic hedgehog in patients with IgA nephropathy are closely associated with intrarenal arteriolar lesions. | Serum levels of sonic hedgehog in patients with IgA nephropathy are closely associated with intrarenal arteriolar lesions. Peng F, Wu L, Wu J, Duan S, He J, Chen P, Wang P, Liu J, Cai G, Zhang C, Chen X. | 01/15/2024 |
Activation of Sonic Hedgehog Signaling Pathway Regulates Human Trabecular Meshwork Cell Function. | Activation of Sonic Hedgehog Signaling Pathway Regulates Human Trabecular Meshwork Cell Function. Wang X, Tan S, Yang S, Liu X, Lei J, Li H. | 09/21/2023 |
Low Expression of the NRP1 Gene Is Associated with Shorter Overall Survival in Patients with Sonic Hedgehog and Group 3 Medulloblastoma. | Low Expression of the NRP1 Gene Is Associated with Shorter Overall Survival in Patients with Sonic Hedgehog and Group 3 Medulloblastoma. de Araújo MA, Malafaia O, Ribas Filho JM, Fratini L, Roesler R, Isolan GR., Free PMC Article | 08/19/2023 |
Expression of Shh, Gli1, and Cyr61 in Gastric Cancer Predicts Overall Survival of Patients: A Retrospective Study. | Expression of Shh, Gli1, and Cyr61 in Gastric Cancer Predicts Overall Survival of Patients: A Retrospective Study. Quan X, Zhang Z, Qin Y, Gai X, Tian Q, Guo Y, Qian J, Yao J., Free PMC Article | 11/12/2022 |
Noncanonical Sonic Hedgehog signaling amplifies platelet reactivity and thrombogenicity. | Noncanonical Sonic Hedgehog signaling amplifies platelet reactivity and thrombogenicity. Tiwari A, Gautam D, Kulkarni PP, Ekhlak M, Sonkar VK, Agrawal V, Dash D., Free PMC Article | 09/17/2022 |
Serum Vitamin D Levels Explored in the Latvian Cohort of Patients with Basal Cell Carcinoma Linked to the Sonic Hedgehog and Vitamin D Binding Protein Cutaneous Tissue Indices. | Serum Vitamin D Levels Explored in the Latvian Cohort of Patients with Basal Cell Carcinoma Linked to the Sonic Hedgehog and Vitamin D Binding Protein Cutaneous Tissue Indices. Moisejenko-Goluboviča J, Groma V, Svirskis Š, Ivanova A., Free PMC Article | 09/17/2022 |
Primary cilia and SHH signaling impairments in human and mouse models of Parkinson's disease. | Primary cilia and SHH signaling impairments in human and mouse models of Parkinson's disease. Schmidt S, Luecken MD, Trümbach D, Hembach S, Niedermeier KM, Wenck N, Pflügler K, Stautner C, Böttcher A, Lickert H, Ramirez-Suastegui C, Ahmad R, Ziller MJ, Fitzgerald JC, Ruf V, van de Berg WDJ, Jonker AJ, Gasser T, Winner B, Winkler J, Vogt Weisenhorn DM, Giesert F, Theis FJ, Wurst W., Free PMC Article | 08/27/2022 |
Combined HIF-1alpha and SHH Up-Regulation Is a Potential Biomarker to Predict Poor Prognosis in Postoperative Hepatocellular Carcinoma. | Combined HIF-1α and SHH Up-Regulation Is a Potential Biomarker to Predict Poor Prognosis in Postoperative Hepatocellular Carcinoma. Zhao J, Zeng G, Lin E, Cai C, Li P, Zou B, Li J. | 07/23/2022 |
Sonic Hedgehog Promotes Proliferation and Migration of Fibroblast-Like Synoviocytes in Rheumatoid Arthritis via Rho/ROCK Signaling. | Sonic Hedgehog Promotes Proliferation and Migration of Fibroblast-Like Synoviocytes in Rheumatoid Arthritis via Rho/ROCK Signaling. Hu Z, Chen Y, Zhu S, Feng X, Zhang B, Huang J., Free PMC Article | 07/9/2022 |
ATRT-SHH comprises three molecular subgroups with characteristic clinical and histopathological features and prognostic significance. | ATRT-SHH comprises three molecular subgroups with characteristic clinical and histopathological features and prognostic significance. Federico A, Thomas C, Miskiewicz K, Woltering N, Zin F, Nemes K, Bison B, Johann PD, Hawes D, Bens S, Kordes U, Albrecht S, Dohmen H, Hauser P, Keyvani K, van Landeghem FKH, Lund EL, Scheie D, Mawrin C, Monoranu CM, Parm Ulhøi B, Pietsch T, Reinhard H, Riemenschneider MJ, Sehested A, Sumerauer D, Siebert R, Paulus W, Frühwald MC, Kool M, Hasselblatt M., Free PMC Article | 06/11/2022 |
A SURF4-to-proteoglycan relay mechanism that mediates the sorting and secretion of a tagged variant of sonic hedgehog. | A SURF4-to-proteoglycan relay mechanism that mediates the sorting and secretion of a tagged variant of sonic hedgehog. Tang X, Chen R, Mesias VSD, Wang T, Wang Y, Poljak K, Fan X, Miao H, Hu J, Zhang L, Huang J, Yao S, Miller EA, Guo Y., Free PMC Article | 05/14/2022 |
The Overexpression of Sonic Hedgehog Associates with Collateral Development and Amelioration of Oxidative Stress in Stroke Patients. | The Overexpression of Sonic Hedgehog Associates with Collateral Development and Amelioration of Oxidative Stress in Stroke Patients. Ghasemi H, Pegah A, Tayebinia H, Khazaei S, Feizi F, Mazaheri S, Ghiasian M, Khazaei M. | 04/30/2022 |
Understanding Abnormal SMO-SHH Signaling in Autism Spectrum Disorder: Potential Drug Target and Therapeutic Goals. | Understanding Abnormal SMO-SHH Signaling in Autism Spectrum Disorder: Potential Drug Target and Therapeutic Goals. Rahi S, Mehan S. | 04/9/2022 |
[Expression and significance of GLI1 and Shh in the malignant transformation of ovarian endometriosis]. | [Expression and significance of GLI1 and Shh in the malignant transformation of ovarian endometriosis]. Zhao F, Yu XP, Zhao H, Song BB, Lyu AW, Zhang SH, Wang LM. | 02/26/2022 |
Dysfunction of Shh signaling activates autophagy to inhibit trophoblast motility in recurrent miscarriage. | Dysfunction of Shh signaling activates autophagy to inhibit trophoblast motility in recurrent miscarriage. Pan Y, Yan L, Chen Q, Wei C, Dai Y, Tong X, Zhu H, Lu M, Zhang Y, Jin X, Zhang T, Lin X, Zhou F, Zhang S., Free PMC Article | 02/19/2022 |
Peptide amphiphile nanofiber hydrogel delivery of Sonic hedgehog protein to the penis and cavernous nerve suppresses intrinsic and extrinsic apoptotic signaling mechanisms, which are an underlying cause of erectile dysfunction. | Peptide amphiphile nanofiber hydrogel delivery of Sonic hedgehog protein to the penis and cavernous nerve suppresses intrinsic and extrinsic apoptotic signaling mechanisms, which are an underlying cause of erectile dysfunction. Martin S, Harrington DA, Ohlander S, Stupp SI, McVary KT, Podlasek CA., Free PMC Article | 02/12/2022 |
Forebrain Shh overexpression improves cognitive function and locomotor hyperactivity in an aneuploid mouse model of Down syndrome and its euploid littermates. | Forebrain Shh overexpression improves cognitive function and locomotor hyperactivity in an aneuploid mouse model of Down syndrome and its euploid littermates. Gao FJ, Klinedinst D, Fernandez FX, Cheng B, Savonenko A, Devenney B, Li Y, Wu D, Pomper MG, Reeves RH., Free PMC Article | 01/29/2022 |
Myomegalin regulates Hedgehog pathway by controlling PDE4D at the centrosome. | Myomegalin regulates Hedgehog pathway by controlling PDE4D at the centrosome. Peng H, Zhang J, Ya A, Ma W, Villa S, Sukenik S, Ge X., Free PMC Article | 01/29/2022 |
Integrated computational analyses reveal novel insights into the stromal microenvironment of SHH-subtype medulloblastoma. | Integrated computational analyses reveal novel insights into the stromal microenvironment of SHH-subtype medulloblastoma. Landry AP, Samuel N, Spears J, Zador Z., Free PMC Article | 01/29/2022 |
Developmental and regenerative paradigms of cilia regulated hedgehog signaling. | Developmental and regenerative paradigms of cilia regulated hedgehog signaling. Kopinke D, Norris AM, Mukhopadhyay S., Free PMC Article | 01/22/2022 |
Hedgehog-Interacting Protein is a multimodal antagonist of Hedgehog signalling. | Hedgehog-Interacting Protein is a multimodal antagonist of Hedgehog signalling. Griffiths SC, Schwab RA, El Omari K, Bishop B, Iverson EJ, Malinauskas T, Dubey R, Qian M, Covey DF, Gilbert RJC, Rohatgi R, Siebold C., Free PMC Article | 01/22/2022 |