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    BCL11B BCL11 transcription factor B [ Homo sapiens (human) ]

    Gene ID: 64919, updated on 7-Jul-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Association between BCL11B gene polymorphisms and age-related hearing loss in the elderly: A case-control study in Qingdao, China.

    Association between BCL11B gene polymorphisms and age-related hearing loss in the elderly: A case-control study in Qingdao, China.
    Li X, Zhang J, Zhang H, Ren J, Cao H, Xu Y, Zhang D, Duan H., Free PMC Article

    06/11/2024
    A Bcl11b[N797K] variant isolated from an immunodeficient patient inhibits early thymocyte development in mice.

    A Bcl11b(N797K) variant isolated from an immunodeficient patient inhibits early thymocyte development in mice.
    Matsumoto K, Okuyama K, Sidwell T, Yamashita M, Endo T, Satoh-Takayama N, Ohno H, Morio T, Rothenberg EV, Taniuchi I., Free PMC Article

    03/22/2024
    The function of BCL11B in base excision repair contributes to its dual role as an oncogene and a haplo-insufficient tumor suppressor gene.

    The function of BCL11B in base excision repair contributes to its dual role as an oncogene and a haplo-insufficient tumor suppressor gene.
    Vickridge E, Faraco CCF, Lo F, Rahimian H, Liu ZY, Tehrani PS, Djerir B, Ramdzan ZM, Leduy L, Maréchal A, Gingras AC, Nepveu A., Free PMC Article

    01/26/2024
    Differential expression of BCL11b and CDKN2A in CD30-positive peripheral T cell lymphoma: Retrospective study.

    Differential expression of BCL11b and CDKN2A in CD30-positive peripheral T cell lymphoma: Retrospective study.
    Wang Y, Zhang F, Gao N, Bu P, Cui W, Xi Y., Free PMC Article

    11/27/2023
    BCL11B and the NuRD complex cooperatively guard T-cell fate and inhibit OPA1-mediated mitochondrial fusion in T cells.

    BCL11B and the NuRD complex cooperatively guard T-cell fate and inhibit OPA1-mediated mitochondrial fusion in T cells.
    Liao R, Wu Y, Qin L, Jiang Z, Gou S, Zhou L, Hong Q, Li Y, Shi J, Yao Y, Lai L, Li Y, Liu P, Thiery JP, Qin D, Graf T, Liu X, Li P.,

    11/8/2023
    BCL11B Upregulates the Expression of RelA in T Cells Stimulated with Staphylococcal Enterotoxin A.

    BCL11B Upregulates the Expression of RelA in T Cells Stimulated with Staphylococcal Enterotoxin A.
    Yan Y, Wang S, Lin C.

    01/14/2023
    Expression pattern and diagnostic utility of BCL11B in mature T- and NK-cell neoplasms.

    Expression pattern and diagnostic utility of BCL11B in mature T- and NK-cell neoplasms.
    Fang H, Khoury JD, Torres-Cabala CA, Ng SB, Xu J, El Hussein S, Hu S, Vega F, Li S, Tang Z, Tang G, Medeiros LJ, Wang W.

    12/3/2022
    Epigenome-wide analysis of T-cell large granular lymphocytic leukemia identifies BCL11B as a potential biomarker.

    Epigenome-wide analysis of T-cell large granular lymphocytic leukemia identifies BCL11B as a potential biomarker.
    Johansson P, Laguna T, Ossowski J, Pancaldi V, Brauser M, Dührsen U, Keuneke L, Queiros A, Richter J, Martín-Subero JI, Siebert R, Schlegelberger B, Küppers R, Dürig J, Murga Penas EM, Carillo-de Santa Pau E, Bergmann AK., Free PMC Article

    11/26/2022
    A de novo BCL11B variant case manifesting with dystonic movement disorder regarding the article ""BCL11B-related disorder in two canadian children: Expanding the clinical phenotype (Prasad et al., 2020).""

    A de novo BCL11B variant case manifesting with dystonic movement disorder regarding the article "BCL11B-related disorder in two canadian children: Expanding the clinical phenotype (Prasad et al., 2020).".
    Harrer P, Leppmeier V, Berger A, Demund S, Winkelmann J, Berweck S, Zech M.

    11/5/2022
    Decreased TCF1 and BCL11B expression predicts poor prognosis for patients with chronic lymphocytic leukemia.

    Decreased TCF1 and BCL11B expression predicts poor prognosis for patients with chronic lymphocytic leukemia.
    Liang T, Wang X, Liu Y, Ai H, Wang Q, Wang X, Wei X, Song Y, Yin Q., Free PMC Article

    10/15/2022
    Oncogenic isoform switch of tumor suppressor BCL11B in adult T-cell leukemia/lymphoma.

    Oncogenic isoform switch of tumor suppressor BCL11B in adult T-cell leukemia/lymphoma.
    Permatasari HK, Nakahata S, Ichikawa T, Fauzi YR, Kiyonari H, Shide K, Kameda T, Shimoda K, Ono M, Taki T, Taniwaki M, Futakuchi M, Morishita K.

    06/25/2022
    Diagnostic challenge of identifying cases with recurrent t(8;14)(q24.21;q32.2) Involving BCL11B in acute leukemias of ambiguous lineage: an analysis of eight patients.

    Diagnostic challenge of identifying cases with recurrent t(8;14)(q24.21;q32.2) Involving BCL11B in acute leukemias of ambiguous lineage: an analysis of eight patients.
    Bendig S, Stengel A, Walter W, Meggendorfer M, Baer C, Müller ML, Haferlach T, Kern W, Haferlach C.

    04/23/2022
    Enhancer Hijacking Drives Oncogenic BCL11B Expression in Lineage-Ambiguous Stem Cell Leukemia.

    Enhancer Hijacking Drives Oncogenic BCL11B Expression in Lineage-Ambiguous Stem Cell Leukemia.
    Montefiori LE, Bendig S, Gu Z, Chen X, Pölönen P, Ma X, Murison A, Zeng A, Garcia-Prat L, Dickerson K, Iacobucci I, Abdelhamed S, Hiltenbrand R, Mead PE, Mehr CM, Xu B, Cheng Z, Chang TC, Westover T, Ma J, Stengel A, Kimura S, Qu C, Valentine MB, Rashkovan M, Luger S, Litzow MR, Rowe JM, den Boer ML, Wang V, Yin J, Kornblau SM, Hunger SP, Loh ML, Pui CH, Yang W, Crews KR, Roberts KG, Yang JJ, Relling MV, Evans WE, Stock W, Paietta EM, Ferrando AA, Zhang J, Kern W, Haferlach T, Wu G, Dick JE, Klco JM, Haferlach C, Mullighan CG., Free PMC Article

    03/19/2022
    Human cytomegalovirus expands a CD8(+) T cell population with loss of BCL11B expression and gain of NK cell identity.

    Human cytomegalovirus expands a CD8(+) T cell population with loss of BCL11B expression and gain of NK cell identity.
    Sottile R, Panjwani MK, Lau CM, Daniyan AF, Tanaka K, Barker JN, Brentjens RJ, Sun JC, Le Luduec JB, Hsu KC., Free PMC Article

    03/5/2022
    The transcription factor Bcl11b promotes both canonical and adaptive NK cell differentiation.

    The transcription factor Bcl11b promotes both canonical and adaptive NK cell differentiation.
    Holmes TD, Pandey RV, Helm EY, Schlums H, Han H, Campbell TM, Drashansky TT, Chiang S, Wu CY, Tao C, Shoukier M, Tolosa E, Von Hardenberg S, Sun M, Klemann C, Marsh RA, Lau CM, Lin Y, Sun JC, Månsson R, Cichocki F, Avram D, Bryceson YT., Free PMC Article

    02/19/2022
    Redefining the biological basis of lineage-ambiguous leukemia through genomics: BCL11B deregulation in acute leukemias of ambiguous lineage.

    Redefining the biological basis of lineage-ambiguous leukemia through genomics: BCL11B deregulation in acute leukemias of ambiguous lineage.
    Montefiori LE, Mullighan CG., Free PMC Article

    01/22/2022
    B-cell lymphoma/leukaemia 11B (BCL11B) expression status helps distinguish early T-cell precursor acute lymphoblastic leukaemia/lymphoma (ETP-ALL/LBL) from other subtypes of T-cell ALL/LBL.

    B-cell lymphoma/leukaemia 11B (BCL11B) expression status helps distinguish early T-cell precursor acute lymphoblastic leukaemia/lymphoma (ETP-ALL/LBL) from other subtypes of T-cell ALL/LBL.
    Fang H, Wang W, El Hussein S, Morita K, Beird HC, Mitra A, Loghavi S, Lin P, Jabbour EJ, Khoury JD.

    12/18/2021
    14q32 rearrangements deregulating BCL11B mark a distinct subgroup of T-lymphoid and myeloid immature acute leukemia.

    14q32 rearrangements deregulating BCL11B mark a distinct subgroup of T-lymphoid and myeloid immature acute leukemia.
    Di Giacomo D, La Starza R, Gorello P, Pellanera F, Kalender Atak Z, De Keersmaecker K, Pierini V, Harrison CJ, Arniani S, Moretti M, Testoni N, De Santis G, Roti G, Matteucci C, Bassan R, Vandenberghe P, Aerts S, Cools J, Bornhauser B, Bourquin JP, Piazza R, Mecucci C., Free PMC Article

    12/4/2021
    [Expression of GATA3 and bcl-11b in peripheral T-cell lymphoma and their clinical significance].

    [Expression of GATA3 and bcl-11b in peripheral T-cell lymphoma and their clinical significance].
    Wang YJ, Zhang HL, Li J, Bu P, Zhang F, Xi YF.

    09/18/2021
    A de novo substitution in BCL11B leads to loss of interaction with transcriptional complexes and craniosynostosis.

    A de novo substitution in BCL11B leads to loss of interaction with transcriptional complexes and craniosynostosis.
    Goos JAC, Vogel WK, Mlcochova H, Millard CJ, Esfandiari E, Selman WH, Calpena E, Koelling N, Carpenter EL, Swagemakers SMA, van der Spek PJ, Filtz TM, Schwabe JWR, Iwaniec UT, Mathijssen IMJ, Leid M, Twigg SRF., Free PMC Article

    09/4/2021
    Genes regulated by BCL11B during T-cell development are enriched for de novo mutations found in schizophrenia patients.

    Genes regulated by BCL11B during T-cell development are enriched for de novo mutations found in schizophrenia patients.
    Fahey L, Donohoe G, Broin PÓ, Morris DW.

    05/15/2021
    Distinct Notch1 and BCL11B requirements mediate human gammadelta/alphabeta T cell development.

    Distinct Notch1 and BCL11B requirements mediate human γδ/αβ T cell development.
    Dolens AC, Durinck K, Lavaert M, Van der Meulen J, Velghe I, De Medts J, Weening K, Roels J, De Mulder K, Volders PJ, De Preter K, Kerre T, Vandekerckhove B, Leclercq G, Vandesompele J, Mestdagh P, Van Vlierberghe P, Speleman F, Taghon T., Free PMC Article

    05/8/2021
    Role of cancer stem cell markers ALDH1, BCL11B, BMI-1, and CD44 in the prognosis of advanced HNSCC.

    Role of cancer stem cell markers ALDH1, BCL11B, BMI-1, and CD44 in the prognosis of advanced HNSCC.
    Jakob M, Sharaf K, Schirmer M, Leu M, Küffer S, Bertlich M, Ihler F, Haubner F, Canis M, Kitz J., Free PMC Article

    05/8/2021
    BCL11B suppresses tumor progression and stem cell traits in hepatocellular carcinoma by restoring p53 signaling activity.

    BCL11B suppresses tumor progression and stem cell traits in hepatocellular carcinoma by restoring p53 signaling activity.
    Yang WJ, Sun YF, Jin AL, Lv LH, Zhu J, Wang BL, Zhou Y, Zhang CY, Wang H, Hu B, Wang PX, Te L, Pan BS, Zhou J, Fan J, Yang XR, Guo W., Free PMC Article

    04/13/2021
    Endocannabinoid signalling in stem cells and cerebral organoids drives differentiation to deep layer projection neurons via CB1 receptors.

    Endocannabinoid signalling in stem cells and cerebral organoids drives differentiation to deep layer projection neurons via CB(1) receptors.
    Paraíso-Luna J, Aguareles J, Martín R, Ayo-Martín AC, Simón-Sánchez S, García-Rincón D, Costas-Insua C, García-Taboada E, de Salas-Quiroga A, Díaz-Alonso J, Liste I, Sánchez-Prieto J, Cappello S, Guzmán M, Galve-Roperh I.

    02/2/2021
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