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    BMP2 bone morphogenetic protein 2 [ Homo sapiens (human) ]

    Gene ID: 650, updated on 17-Jun-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    MicroRNA 98-5p Overexpression Contributes to Delayed Fracture Healing via Targeting BMP-2.

    MicroRNA 98-5p Overexpression Contributes to Delayed Fracture Healing via Targeting BMP-2.
    Zhang YB, Guo XQ, Wang GG, Pu HB.

    06/5/2024
    RUNX1-BMP2 promotes vasculogenic mimicry in laryngeal squamous cell carcinoma via activation of the PI3K-AKT signaling pathway.

    RUNX1-BMP2 promotes vasculogenic mimicry in laryngeal squamous cell carcinoma via activation of the PI3K-AKT signaling pathway.
    Zhu Q, Zhang X, Lu F, Miao S, Zhang C, Liu Z, Gao Z, Qi M, An X, Geng P, Wang S, Ren H, Han F, Zhang R, Zha D., Free PMC Article

    04/17/2024
    Whole genome sequencing identifies associations for nonsyndromic sagittal craniosynostosis with the intergenic region of BMP2 and noncoding RNA gene LINC01428.

    Whole genome sequencing identifies associations for nonsyndromic sagittal craniosynostosis with the intergenic region of BMP2 and noncoding RNA gene LINC01428.
    Musolf AM, Justice CM, Erdogan-Yildirim Z, Goovaerts S, Cuellar A, Shaffer JR, Marazita ML, Claes P, Weinberg SM, Li J, Senders C, Zwienenberg M, Simeonov E, Kaneva R, Roscioli T, Di Pietro L, Barba M, Lattanzi W, Cunningham ML, Romitti PA, Boyadjiev SA., Free PMC Article

    04/17/2024
    miR-539-5p targets BMP2 to regulate Treg activation in B-cell acute lymphoblastic leukemia through TGF-beta/Smads/MAPK.

    miR-539-5p targets BMP2 to regulate Treg activation in B-cell acute lymphoblastic leukemia through TGF-β/Smads/MAPK.
    Dai Q, Shi R, Zhang G, Wang Y, Ye L, Peng L, Guo S, He J, Yang H, Jiang Y., Free PMC Article

    03/25/2024
    BMP2 rs1005464 is associated with mandibular condyle size variation.

    BMP2 rs1005464 is associated with mandibular condyle size variation.
    Marañón-Vásquez GA, de Souza Araújo MT, de Oliveira Ruellas AC, Matsumoto MAN, Figueiredo M, Meyfarth SRS, Antunes LAA, Baratto-Filho F, Scariot R, Flores-Mir C, Kirschneck C, Santos Antunes L, Küchler EC., Free PMC Article

    03/14/2024
    Endometrial BMP2 Deficiency Impairs ITGB3-Mediated Trophoblast Invasion in Women With Repeated Implantation Failure.

    Endometrial BMP2 Deficiency Impairs ITGB3-Mediated Trophoblast Invasion in Women With Repeated Implantation Failure.
    Hu C, Deng J, Liu M, Ni T, Chen ZJ, Yan J, Li Y.

    02/5/2024
    ATOH8 Expression Is Regulated by BMP2 and Plays a Key Role in Human Endometrial Stromal Cell Decidualization.

    ATOH8 Expression Is Regulated by BMP2 and Plays a Key Role in Human Endometrial Stromal Cell Decidualization.
    Thapa R, Druessel L, Ma L, Torry DS, Bany BM.,

    12/28/2023
    MicroRNA 211-5p inhibits cancer cell proliferation and migration in pancreatic cancer by targeting BMP2.

    MicroRNA 211-5p inhibits cancer cell proliferation and migration in pancreatic cancer by targeting BMP2.
    Li D, Luo C, Deng J, Xu Y, Fu S, Liu K, Wu J., Free PMC Article

    12/28/2023
    BMP-9 Improves the Osteogenic Differentiation Ability over BMP-2 through p53 Signaling In Vitro in Human Periosteum-Derived Cells.

    BMP-9 Improves the Osteogenic Differentiation Ability over BMP-2 through p53 Signaling In Vitro in Human Periosteum-Derived Cells.
    Park JH, Koh EB, Seo YJ, Oh HS, Byun JH., Free PMC Article

    11/1/2023
    BMP2 is a potential causative gene for isolated dextrocardia situs solitus.

    BMP2 is a potential causative gene for isolated dextrocardia situs solitus.
    Yogi A, Iemura R, Nakatani H, Takasawa K, Gau M, Yamauchi T, Yoshida M, Moriyama K, Ishii T, Hosokawa S, Yamada M, Suzuki H, Kosaki K, Kashimada K, Morio T.

    09/13/2023
    H3K27me3-modulated Hofbauer cell BMP2 signalling enhancement compensates for shallow trophoblast invasion in preeclampsia.

    H3K27me3-modulated Hofbauer cell BMP2 signalling enhancement compensates for shallow trophoblast invasion in preeclampsia.
    Deng J, Zhao HJ, Zhong Y, Hu C, Meng J, Wang C, Lan X, Wang X, Chen ZJ, Yan J, Wang W, Li Y., Free PMC Article

    09/6/2023
    Monoallelic loss-of-function BMP2 variants result in BMP2-related skeletal dysplasia spectrum.

    Monoallelic loss-of-function BMP2 variants result in BMP2-related skeletal dysplasia spectrum.
    Priestley JRC, Deshwar AR, Murthy H, D'Agostino MD, Dupuis L, Gangaram B, Gray C, Jobling R, Pannia E, Platzer K, Prescott K, Redman M, Rippert AL, Rosenfeld JA, Scott DA, Wang YW, Schmederer Z, Dalal A, Sarma AS, Skraban C, Dowling JJ, Mendoza-Londono R, Slavotinek A, Bhoj EJ.

    08/10/2023
    Secreted phosphoprotein 24 kD (Spp24) inhibits the growth of human osteosarcoma through the BMP-2/Smad signaling pathway.

    Secreted phosphoprotein 24 kD (Spp24) inhibits the growth of human osteosarcoma through the BMP-2/Smad signaling pathway.
    Chen H, Li C, Zhou T, Li X, Duarte MEL, Daubs MD, Buser Z, Brochmann EJ, Wang JC, Murray SS, Jiao L, Tian H.

    07/31/2023
    Kielin/chordin-like protein enhances induction of osteoblast differentiation by Bone Morphogenetic Protein-2.

    Kielin/chordin-like protein enhances induction of osteoblast differentiation by Bone Morphogenetic Protein-2.
    Nagasaki K, Yamada A, Sasa K, Kamijo R., Free PMC Article

    07/7/2023
    BMP2 induces osteogenic differentiation through ACKR3 in mesenchymal stem cells.

    BMP2 induces osteogenic differentiation through ACKR3 in mesenchymal stem cells.
    Liu J, Yao XT, Feng XL, Bai XZ.

    06/12/2023
    BMP-2 Genome-Edited Human MSCs Protect against Cartilage Degeneration via Suppression of IL-34 in Collagen-Induced Arthritis.

    BMP-2 Genome-Edited Human MSCs Protect against Cartilage Degeneration via Suppression of IL-34 in Collagen-Induced Arthritis.
    Chae DS, Han S, Lee MK, Kim SW., Free PMC Article

    05/22/2023
    BMP-2 and IL-1beta as Markers of Nasal Mucosa Inflammation in Rhinosinusitis with Nasal Polyps.

    BMP-2 and IL-1β as Markers of Nasal Mucosa Inflammation in Rhinosinusitis with Nasal Polyps.
    Matveeva NY, Pavlush DG, Kalinichenko SG.

    04/4/2023
    Functional analysis of the long-range regulatory element of BMP2 gene.

    Functional analysis of the long-range regulatory element of BMP2 gene.
    Wan XQ, Wei WZ, Guo SL, Cui YX, Jing XY, Huang LJ, Ma J.

    03/20/2023
    Structural analysis of the interaction between human cytokine BMP-2 and the antagonist Noggin reveals molecular details of cell chondrogenesis inhibition.

    Structural analysis of the interaction between human cytokine BMP-2 and the antagonist Noggin reveals molecular details of cell chondrogenesis inhibition.
    Robert C, Kerff F, Bouillenne F, Gavage M, Vandevenne M, Filée P, Matagne A., Free PMC Article

    02/24/2023
    PI3K-Akt signaling regulates BMP2-induced osteogenic differentiation of mesenchymal stem cells (MSCs): A transcriptomic landscape analysis.

    PI3K-Akt signaling regulates BMP2-induced osteogenic differentiation of mesenchymal stem cells (MSCs): A transcriptomic landscape analysis.
    Gao S, Chen B, Zhu Z, Du C, Zou J, Yang Y, Huang W, Liao J.

    02/4/2023
    OLMALINC/OCT4/BMP2 axis enhances osteogenic-like phenotype of renal interstitial fibroblasts to participate in Randall's plaque formation.

    OLMALINC/OCT4/BMP2 axis enhances osteogenic-like phenotype of renal interstitial fibroblasts to participate in Randall's plaque formation.
    Zhu Z, Huang F, Jiang Y, Ruan S, Liu M, Zhang Y, Li Y, Chen J, Cui Y, Chen Z, Chen H, Zeng F., Free PMC Article

    01/11/2023
    Assessing the prevalence of S-shaped root canal and associated genes in humans.

    Assessing the prevalence of S-shaped root canal and associated genes in humans.
    Küchler EC, Stroparo JLO, Matsumoto MN, Scariot R, Perin CP, Roskamp L, Menezes-Oliveira MAH, Proff P, Kirschneck C, Baratto-Filho F.

    10/29/2022
    CoCl2 -simulated hypoxia potentiates the osteogenic differentiation of fibroblasts derived from tympanosclerosis by upregulating the expression of BMP-2.

    CoCl(2) -simulated hypoxia potentiates the osteogenic differentiation of fibroblasts derived from tympanosclerosis by upregulating the expression of BMP-2.
    Zhang C, Liu YW, Chen M, Min S, Mao J, Li Q, Chi Z.

    08/13/2022
    Inhibition of miR985p promotes high glucoseinduced suppression of preosteoblast proliferation and differentiation via the activation of the PI3K/AKT/GSK3beta signaling pathway by targeting BMP2.

    Inhibition of miR‑98‑5p promotes high glucose‑induced suppression of preosteoblast proliferation and differentiation via the activation of the PI3K/AKT/GSK3β signaling pathway by targeting BMP2.
    Zheng F, Zhang F, Wang F., Free PMC Article

    08/6/2022
    Association between Bone Morphogenetic Protein 2 Gene Polymorphisms and Skeletal Fluorosis of The Brick-tea Type Fluorosis in Tibetans and Kazakhs, China.

    Association between Bone Morphogenetic Protein 2 Gene Polymorphisms and Skeletal Fluorosis of The Brick-tea Type Fluorosis in Tibetans and Kazakhs, China.
    Lou Q, Guo N, Huang W, Wu L, Su M, Liu Y, Liu X, Li B, Yang Y, Gao Y.

    07/2/2022
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