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    SLC6A4 solute carrier family 6 member 4 [ Homo sapiens (human) ]

    Gene ID: 6532, updated on 15-Oct-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Early-life adversity severity, timing, and context type are associated with SLC6A4 methylation in emerging adults: Results from a prospective cohort study.

    Early-life adversity severity, timing, and context type are associated with SLC6A4 methylation in emerging adults: Results from a prospective cohort study.
    Koning SM, Kessler CL, Canli T, Duman EA, Adam EK, Zinbarg R, Craske MG, Stephens JE, Vrshek-Schallhorn S.

    10/9/2024
    Connection Failure: Differences in White Matter Microstructure Are Associated with 5-HTTLPR but Not with Risk Seeking for Losses.

    Connection Failure: Differences in White Matter Microstructure Are Associated with 5-HTTLPR but Not with Risk Seeking for Losses.
    Neukam PT, Müller DK, Deza-Lougovski YI, Pooseh S, Witt SH, Rietschel M, Smolka MN., Free PMC Article

    07/4/2024
    PPARgamma dependent PEX11beta counteracts the suppressive role of SIRT1 on neural differentiation of HESCs.

    PPARgamma dependent PEX11beta counteracts the suppressive role of SIRT1 on neural differentiation of HESCs.
    Esmaeili M, Nasr-Esfahani MH, Shoaraye Nejati A, Safaeinejad Z, Atefi A, L Megraw T, Ghaedi K., Free PMC Article

    06/13/2024
    [The association of polymorphisms of the serotonin transporter gene SLC6A4 with depression].

    [The association of polymorphisms of the serotonin transporter gene SLC6A4 with depression].
    Gafarov VV, Gromova EA, Gubina MA, Gagulin IV, Maksimov VN, Gafarova AV.

    03/14/2024
    Tailoring Type II Diabetes Treatment: Investigating the Effect of 5-HTT Polymorphisms on HbA1c Levels after Metformin Initiation.

    Tailoring Type II Diabetes Treatment: Investigating the Effect of 5-HTT Polymorphisms on HbA1c Levels after Metformin Initiation.
    Ochi T, de Vos S, Touw D, Denig P, Feenstra T, Hak E., Free PMC Article

    03/1/2024
    SLC6A4 gene variants moderate associations between childhood food insecurity and adolescent mental health.

    SLC6A4 gene variants moderate associations between childhood food insecurity and adolescent mental health.
    Pilkay S, Nolasco M, Nunes S, Riffer A, Femia D, Halevy D, Veerman T, Heiland S, Suwannimit N, Trexler N, Gump B., Free PMC Article

    02/23/2024
    DNA methylation levels of the serotonin transporter gene are not associated with the outcome of highly standardized one-session exposure-based fear treatment.

    DNA methylation levels of the serotonin transporter gene are not associated with the outcome of highly standardized one-session exposure-based fear treatment.
    Wannemüller A, Kumsta R, Moser D, Jöhren HP, Margraf J.

    02/9/2024
    Neuropeptide Y gene variants and Agreeableness: interaction effect with the birth cohort and the serotonin transporter promoter polymorphism.

    Neuropeptide Y gene variants and Agreeableness: interaction effect with the birth cohort and the serotonin transporter promoter polymorphism.
    Kiive E, Kanarik M, Veidebaum T, Harro J.

    01/26/2024
    Molecular Photoswitches Regulating the Activity of the Human Serotonin Transporter.

    Molecular Photoswitches Regulating the Activity of the Human Serotonin Transporter.
    Singer NK, González L, Monari A.

    11/27/2023
    Prenatal serotonin reuptake inhibitor antidepressant exposure, SLC6A4 genetic variations, and cortisol activity in 6-year-old children of depressed mothers: A cohort study.

    Prenatal serotonin reuptake inhibitor antidepressant exposure, SLC6A4 genetic variations, and cortisol activity in 6-year-old children of depressed mothers: A cohort study.
    Zusman EZ, Chau CMY, Bone JN, Hookenson K, Brain U, Glier MB, Grunau RE, Weinberg J, Devlin AM, Oberlander TF.

    11/13/2023
    Unravelling neurotransmitters impairment in primary progressive aphasias.

    Unravelling neurotransmitters impairment in primary progressive aphasias.
    Premi E, Dukart J, Mattioli I, Libri I, Pengo M, Gadola Y, Cotelli M, Manenti R, Binetti G, Gazzina S, Alberici A, Magoni M, Koch G, Gasparotti R, Padovani A, Borroni B., Free PMC Article

    10/25/2023
    Interaction of Val66Met BDNF and 5-HTTLPR polymorphisms with prevalence of post-earthquake 27-F PTSD in Chilean population.

    Interaction of Val66Met BDNF and 5-HTTLPR polymorphisms with prevalence of post-earthquake 27-F PTSD in Chilean population.
    Castillo-Navarrete JL, Vicente B, Schmidt K, Moraga-Escobar E, Rojas-Ponce R, Lagos P, Macaya X, Guzman-Castillo A., Free PMC Article

    09/28/2023
    [Association of SLC6A4 gene c.*670T>G polymorphism with the risk for asthma and peripheral blood cytological characteristics among ethnic Zhuang Chinese population].

    [Association of SLC6A4 gene c.*670T>G polymorphism with the risk for asthma and peripheral blood cytological characteristics among ethnic Zhuang Chinese population].
    Chen G, Xu J, Wei S, Meng M, Lan C, Zhao C, Ma Y.

    09/22/2023
    Altered DNA Methylation of the Serotonin Transporter Gene Associated with Early Life Stress and White Matter Microalterations in Korean Patients with Panic Disorder.

    Altered DNA Methylation of the Serotonin Transporter Gene Associated with Early Life Stress and White Matter Microalterations in Korean Patients with Panic Disorder.
    Kim HJ, Bang M, Park CI, Lee SH.

    09/20/2023
    The serotonin transporter sustains human brown adipose tissue thermogenesis.

    The serotonin transporter sustains human brown adipose tissue thermogenesis.
    Suchacki KJ, Ramage LE, Kwok TC, Kelman A, McNeill BT, Rodney S, Keegan M, Gray C, MacNaught G, Patel D, Fletcher AM, Simpson JP, Carter RN, Semple RK, Homer NZM, Morton NM, van Beek EJR, Wakelin SJ, Stimson RH., Free PMC Article

    08/25/2023
    The long and the short of it: 5-HTTLPR and moral judgement.

    The long and the short of it: 5-HTTLPR and moral judgement.
    Armbruster D, Lesch KP, Strobel A.

    08/16/2023
    Associations of the serotonin transporter gene polymorphism, 5-HTTLPR, and adverse life events with late life depression in the elderly Lithuanian population.

    Associations of the serotonin transporter gene polymorphism, 5-HTTLPR, and adverse life events with late life depression in the elderly Lithuanian population.
    Simonyte S, Grabauskyte I, Macijauskiene J, Lesauskaite V, Lesauskaite V, Kvaal KS, Stewart R., Free PMC Article

    08/11/2023
    ASSESSMENT OF THE ASSOCIATION OF SEROTONIN TRANSPORTER GENE (5-HTTVNTR & 5-HTTLPR) POLYMORPHISM IN PATIENTS WITH FIBROMYALGIA SYNDROME.

    ASSESSMENT OF THE ASSOCIATION OF SEROTONIN TRANSPORTER GENE (5-HTTVNTR & 5-HTTLPR) POLYMORPHISM IN PATIENTS WITH FIBROMYALGIA SYNDROME.
    Parvez S, Fatima G, Mahdi F, Hadi NR, Fedacko J.

    07/24/2023
    Molecular and Functional Relevance of NaV1.8-Induced Atrial Arrhythmogenic Triggers in a Human SCN10A Knock-Out Stem Cell Model.

    Molecular and Functional Relevance of Na(V)1.8-Induced Atrial Arrhythmogenic Triggers in a Human SCN10A Knock-Out Stem Cell Model.
    Hartmann N, Knierim M, Maurer W, Dybkova N, Hasenfuß G, Sossalla S, Streckfuss-Bömeke K., Free PMC Article

    06/30/2023
    A Role for the Serotonin Transporter in the Largely Unknown Molecular Pathophysiology of Premenstrual Dysphoric Disorder.

    A Role for the Serotonin Transporter in the Largely Unknown Molecular Pathophysiology of Premenstrual Dysphoric Disorder.
    Meyer JH.

    06/3/2023
    Associations of SLC6A4 methylation with salivary cortisol, salivary alpha-amylase, and subjective stress in everyday life.

    Associations of SLC6A4 methylation with salivary cortisol, salivary alpha-amylase, and subjective stress in everyday life.
    Stoffel M, Rahn S, Neubauer AB, Moessner M, Aguilar-Raab C, Ditzen B.

    06/1/2023
    Multi-state Model-Based Identification of Cryptic Allosteric Sites on Human Serotonin Transporter.

    Multi-state Model-Based Identification of Cryptic Allosteric Sites on Human Serotonin Transporter.
    Tu G, Xu B, Luo D, Liu J, Liu Z, Chen G, Xue W.

    05/5/2023
    HTR1A, TPH2, and 5-HTTLPR Polymorphisms and Their Impact on the Severity of Depressive Symptoms and on the Concentration of Tryptophan Catabolites during Hepatitis C Treatment with Pegylated Interferon-alpha2a and Oral Ribavirin (PEG-IFN-alpha2a/RBV).

    HTR1A, TPH2, and 5-HTTLPR Polymorphisms and Their Impact on the Severity of Depressive Symptoms and on the Concentration of Tryptophan Catabolites during Hepatitis C Treatment with Pegylated Interferon-α2a and Oral Ribavirin (PEG-IFN-α2a/RBV).
    Pawlowski T, Malyszczak K, Pawlak D, Inglot M, Zalewska M, Grzywacz A, Radkowski M, Laskus T, Janocha-Litwin J, Frydecka D., Free PMC Article

    04/14/2023
    Serotonin, ghrelin, and motilin gene/receptor/transporter polymorphisms in childhood functional constipation.

    Serotonin, ghrelin, and motilin gene/receptor/transporter polymorphisms in childhood functional constipation.
    Arslan B, Dogan G, Orenay-Boyacioglu S, Caliskan M, Elevli M., Free PMC Article

    03/10/2023
    Association of serotonin transporter promoter polymorphism (5-HTTLPR) with orocecal transit time in irritable bowel syndrome.

    Association of serotonin transporter promoter polymorphism (5-HTTLPR) with orocecal transit time in irritable bowel syndrome.
    Sikander A, Rana SV, Sinha SK, Prasad KK, Arora SK.

    02/27/2023
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