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    FSCN1 fascin actin-bundling protein 1 [ Homo sapiens (human) ]

    Gene ID: 6624, updated on 3-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    The FSCN1 gene rs2966447 variant is associated with increased serum fascin-1 levels and breast cancer susceptibility.

    The FSCN1 gene rs2966447 variant is associated with increased serum fascin-1 levels and breast cancer susceptibility.
    Abdullah AR, Gamal El-Din AM, Ismail Y, El-Husseiny AA.

    07/29/2024
    N6-methyladenosine methylation on FSCN1 mediated by METTL14/IGF2BP3 contributes to human papillomavirus type 16-infected cervical squamous cell carcinoma.

    N6-methyladenosine methylation on FSCN1 mediated by METTL14/IGF2BP3 contributes to human papillomavirus type 16-infected cervical squamous cell carcinoma.
    Tian Q, Huang J, Zhang Q, Zhao J.

    05/16/2024
    SirT7-mediated transcription of fascin in hyperglycemic glomerular endothelial cells contributes to EndMT in diabetic nephropathy.

    SirT7-mediated transcription of fascin in hyperglycemic glomerular endothelial cells contributes to EndMT in diabetic nephropathy.
    Wu M, Hao Y, Wu X, Zhu M, Chen X, Qi J, Yu Z, Xu H., Free PMC Article

    05/2/2024
    The association of FSCN1 (rs852479, rs1640233) and HOTAIR (rs920778) polymorphisms with the risk of breast cancer in Egyptian women.

    The association of FSCN1 (rs852479, rs1640233) and HOTAIR (rs920778) polymorphisms with the risk of breast cancer in Egyptian women.
    Galal ER, Abdelhakam DA, Ahmed LK, Elhusseny Y, Sayed SEP, Eltaweel NH., Free PMC Article

    04/10/2024
    KAT8/SIRT7-mediated Fascin-K41 acetylation/deacetylation regulates tumor metastasis in esophageal squamous cell carcinoma.

    KAT8/SIRT7-mediated Fascin-K41 acetylation/deacetylation regulates tumor metastasis in esophageal squamous cell carcinoma.
    Li DJ, Cheng YW, Pan JM, Guo ZC, Wang SH, Huang QF, Nie PJ, Shi WQ, Xu XE, Wen B, Zhong JL, Zhang ZD, Wu ZY, Zhao H, Liao LD, Wu JY, Zhang K, Dong G, Li EM, Xu LY.

    04/5/2024
    CircFSCN1 induces tumor progression and triggers epithelial-mesenchymal transition in bladder cancer through augmentation of MDM2-mediated p53 silencing.

    CircFSCN1 induces tumor progression and triggers epithelial-mesenchymal transition in bladder cancer through augmentation of MDM2-mediated p53 silencing.
    Deng W, Chen R, Xiong S, Nie J, Yang H, Jiang M, Hu B, Liu X, Fu B.

    01/16/2024
    Fascin-1 expression is associated with neuroendocrine prostate cancer and directly suppressed by androgen receptor.

    Fascin-1 expression is associated with neuroendocrine prostate cancer and directly suppressed by androgen receptor.
    Turpin A, Delliaux C, Parent P, Chevalier H, Escudero-Iriarte C, Bonardi F, Vanpouille N, Flourens A, Querol J, Carnot A, Leroy X, Herranz N, Lanel T, Villers A, Olivier J, Touzet H, de Launoit Y, Tian TV, Duterque-Coquillaud M., Free PMC Article

    01/3/2024
    Fascin actin-bundling protein 1 regulates non-small cell lung cancer progression by influencing the transcription and splicing of tumorigenesis-related genes.

    Fascin actin-bundling protein 1 regulates non-small cell lung cancer progression by influencing the transcription and splicing of tumorigenesis-related genes.
    Sun Q, Liu R, Zhang H, Zong L, Jing X, Ma L, Li J, Zhang L., Free PMC Article

    12/18/2023
    Fascin in migration and metastasis of breast cancer cells - A review.

    Fascin in migration and metastasis of breast cancer cells - A review.
    Izdebska M, Zielińska W, Krajewski A, Grzanka A.

    11/27/2023
    FSCN1 and epithelial mesenchymal transformation transcription factor expression in human pancreatic intraepithelial neoplasia and ductal adenocarcinoma.

    FSCN1 and epithelial mesenchymal transformation transcription factor expression in human pancreatic intraepithelial neoplasia and ductal adenocarcinoma.
    Morris HT, Bamlet WR, Razidlo GL, Machesky LM.

    11/18/2023
    The Role of Fascin-1 in Human Urologic Cancers: A Promising Biomarker or Therapeutic Target?

    The Role of Fascin-1 in Human Urologic Cancers: A Promising Biomarker or Therapeutic Target?
    Zhang N, Bian Q, Gao Y, Wang Q, Shi Y, Li X, Ma X, Chen H, Zhao Z, Yu H., Free PMC Article

    11/1/2023
    Genetic Polymorphism in FSCN1 rs3801004 C/G and CD44 rs353639 A/C, as Prognostic Factor in Egyptian Breast Cancer Patients.

    Genetic Polymorphism in FSCN1 rs3801004 C/G and CD44 rs353639 A/C, as Prognostic Factor in Egyptian Breast Cancer Patients.
    Ibrahim NE, Raafat Hamed RM, Refaat A, Mosaad YO, Mekawy DM., Free PMC Article

    11/1/2023
    FSCN1 promotes proliferation, invasion and glycolysis via the IRF4/AKT signaling pathway in oral squamous cell carcinoma.

    FSCN1 promotes proliferation, invasion and glycolysis via the IRF4/AKT signaling pathway in oral squamous cell carcinoma.
    Li L, Chen L, Li Z, Huang S, Chen Y, Li Z, Chen W., Free PMC Article

    10/20/2023
    Downregulation of fascin induces collective cell migration in triple-negative breast cancer.

    Downregulation of fascin induces collective cell migration in triple‑negative breast cancer.
    Yamamoto Y, Hayashi Y, Sakaki H, Murakami I., Free PMC Article

    06/24/2023
    SYTL2 promotes metastasis of prostate cancer cells by enhancing FSCN1-mediated pseudopodia formation and invasion.

    SYTL2 promotes metastasis of prostate cancer cells by enhancing FSCN1-mediated pseudopodia formation and invasion.
    Li Z, Tao Y, Gao Z, Peng S, Lai Y, Li K, Chen X, Huang H., Free PMC Article

    05/22/2023
    FSCN1 as a new druggable target in adrenocortical carcinoma.

    FSCN1 as a new druggable target in adrenocortical carcinoma.
    Ruggiero C, Tamburello M, Rossini E, Zini S, Durand N, Cantini G, Cioppi F, Hantel C, Kiseljak-Vassiliades K, Wierman ME, Landwehr LS, Weigand I, Kurlbaum M, Zizioli D, Turtoi A, Yang S, Berruti A, Luconi M, Sigala S, Lalli E.

    05/12/2023
    Lactate-mediated Fascin protrusions promote cell adhesion and migration in cervical cancer.

    Lactate-mediated Fascin protrusions promote cell adhesion and migration in cervical cancer.
    Han X, Du S, Chen X, Min X, Dong Z, Wang Y, Zhu C, Wei F, Gao S, Cai Q., Free PMC Article

    05/12/2023
    The role and regulatory mechanism of FSCN1 in breast tumorigenesis and progression.

    The role and regulatory mechanism of FSCN1 in breast tumorigenesis and progression.
    Chang D, Liu XX, Liu R, Sun JW.

    03/20/2023
    Transcriptome analysis reveals the potential biological function of FSCN1 in HeLa cervical cancer cells.

    Transcriptome analysis reveals the potential biological function of FSCN1 in HeLa cervical cancer cells.
    Guo F, Liu Y, Cheng Y, Zhang Q, Quan W, Wei Y, Hong L., Free PMC Article

    01/21/2023
    Long noncoding RNA CDKN2B-AS1 silencing protects against esophageal cancer cell invasion and migration by inactivating the TFAP2A/FSCN1 axis.

    Long noncoding RNA CDKN2B-AS1 silencing protects against esophageal cancer cell invasion and migration by inactivating the TFAP2A/FSCN1 axis.
    Zhu JL, Xue WB, Jiang ZB, Feng W, Liu YC, Nie XY, Jin LY.

    12/24/2022
    The post-translational modification of Fascin: impact on cell biology and its associations with inhibiting tumor metastasis.

    The post-translational modification of Fascin: impact on cell biology and its associations with inhibiting tumor metastasis.
    Nan-Li, Zhang ZD, Li RR, Chen JY, Huang HX, Cheng YW, Xu LY, Li EM.

    12/10/2022
    Role of FSCN1 in the tumor microenvironment of lung squamous cell carcinoma.

    Role of FSCN1 in the tumor microenvironment of lung squamous cell carcinoma.
    Liang JS, Liu SQ, Yan CZ, Xiong M, Lin AY, Zhang X, Xiao J, Jiang W, Dong YQ.

    06/18/2022
    Study on the Function and Mechanism of miR-585-3p Inhibiting the Progression of Ovarian Cancer Cells by Targeting FSCN1 to Block the MAPK Signaling Pathway.

    Study on the Function and Mechanism of miR-585-3p Inhibiting the Progression of Ovarian Cancer Cells by Targeting FSCN1 to Block the MAPK Signaling Pathway.
    Jia Y, Li J, Wang J, Luo T, Jing X, Zhao H., Free PMC Article

    05/28/2022
    TKI resistant-based prognostic immune related gene signature in LUAD, in which FSCN1 contributes to tumor progression.

    TKI resistant-based prognostic immune related gene signature in LUAD, in which FSCN1 contributes to tumor progression.
    Shi Y, Xu Y, Xu Z, Wang H, Zhang J, Wu Y, Tang B, Zheng S, Wang K.

    04/30/2022
    Fascin enhances the vulnerability of breast cancer to erastin-induced ferroptosis.

    Fascin enhances the vulnerability of breast cancer to erastin-induced ferroptosis.
    Chen C, Xie B, Li Z, Chen L, Chen Y, Zhou J, Ju S, Zhou Y, Zhang X, Zhuo W, Yang J, Mao M, Xu L, Wang L., Free PMC Article

    04/16/2022
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