| Classification of IDH wild-type glioblastoma tumorspheres into low- and high-invasion groups based on their transcriptional program. | Classification of IDH wild-type glioblastoma tumorspheres into low- and high-invasion groups based on their transcriptional program.
Park J, Shim JK, Lee M, Kim D, Yoon SJ, Moon JH, Kim EH, Park JY, Chang JH, Kang SG., Free PMC Article | 10/11/2023 |
| Cellular myofibromas with SRF fusions: clinicopathological and molecular study of 3 cases of a rare entity and a potential mimic of sarcoma. | Cellular myofibromas with SRF fusions: clinicopathological and molecular study of 3 cases of a rare entity and a potential mimic of sarcoma.
Papa B, Nguyen MA, Kumar A, Song L, Dorwal P, Cheah AL. | 08/16/2023 |
| SRF/MRTF-A and liver cirrhosis: Pathologic associations. | SRF/MRTF-A and liver cirrhosis: Pathologic associations.
Al-Hetty HRAK, Ismaeel GL, Mohammad WT, Toama MA, Kandeel M, Saleh MM, Turki Jalil A. | 03/1/2023 |
| IGF2BP2, an RNA-binding protein regulates cell proliferation and osteogenic differentiation by stabilizing SRF mRNA. | IGF2BP2, an RNA-binding protein regulates cell proliferation and osteogenic differentiation by stabilizing SRF mRNA.
Zhou Z, Chen S, Wu T, Chen Y, Cao Y, Huang Y, Liu D. | 01/21/2023 |
| SRF is a nonhistone methylation target of KDM2B and SET7 in the regulation of skeletal muscle differentiation. | SRF is a nonhistone methylation target of KDM2B and SET7 in the regulation of skeletal muscle differentiation.
Kwon DH, Kang JY, Joung H, Kim JY, Jeong A, Min HK, Shin S, Lee YG, Kim YK, Seo SB, Kook H., Free PMC Article | 02/19/2022 |
| Cumulus cells of euploid versus whole chromosome 21 aneuploid embryos reveal differentially expressed genes. | Cumulus cells of euploid versus whole chromosome 21 aneuploid embryos reveal differentially expressed genes.
Tiegs AW, Titus S, Mehta S, Garcia-Milian R, Seli E, Scott RT Jr. | 02/12/2022 |
| Identification and analysis of micro-exons in AP2/ERF and MADS gene families. | Identification and analysis of micro-exons in AP2/ERF and MADS gene families.
Song Q, Bari A, Li H, Chen LL., Free PMC Article | 12/4/2021 |
| Expression of serum response factor in the lung mesenchyme is essential for development of pulmonary fibrosis. | Expression of serum response factor in the lung mesenchyme is essential for development of pulmonary fibrosis.
Bernau K, Leet JP, Bruhn EM, Tubbs AJ, Zhu T, Sandbo N., Free PMC Article | 10/9/2021 |
| Anti-GPR56 monoclonal antibody potentiates GPR56-mediated Src-Fak signaling to modulate cell adhesion. | Anti-GPR56 monoclonal antibody potentiates GPR56-mediated Src-Fak signaling to modulate cell adhesion.
Chatterjee T, Zhang S, Posey TA, Jacob J, Wu L, Yu W, Francisco LE, Liu QJ, Carmon KS., Free PMC Article | 08/28/2021 |
| Divergent C-terminal motifs in Galpha12 and Galpha13 provide distinct mechanisms of effector binding and SRF activation. | Divergent C-terminal motifs in Gα12 and Gα13 provide distinct mechanisms of effector binding and SRF activation.
Stecky RC, Quick CR, Fleming TL, Mull ML, Vinson VK, Whitley MS, Dover EN, Meigs TE. | 08/7/2021 |
| Serum response factor-cofactor interactions and their implications in disease. | Serum response factor-cofactor interactions and their implications in disease.
Onuh JO, Qiu H., Free PMC Article | 07/24/2021 |
| MRTF: Basic Biology and Role in Kidney Disease. | MRTF: Basic Biology and Role in Kidney Disease.
Miranda MZ, Lichner Z, Szászi K, Kapus A., Free PMC Article | 07/17/2021 |
| Establishment and Characterization of a Cell Line (S-RMS1) Derived from an Infantile Spindle Cell Rhabdomyosarcoma with SRF-NCOA2 Fusion Transcript. | Establishment and Characterization of a Cell Line (S-RMS1) Derived from an Infantile Spindle Cell Rhabdomyosarcoma with SRF-NCOA2 Fusion Transcript.
Colletti M, Galardi A, Miele E, Di Paolo V, Russo I, De Stefanis C, De Vito R, Rinelli M, Ciolfi A, De Angelis B, Zin A, Guffanti A, Digilio MC, Novelli A, Alaggio R, Milano GM, Di Giannatale A., Free PMC Article | 06/19/2021 |
| SRF Fusions Other Than With RELA Expand the Molecular Definition of SRF-fused Perivascular Tumors. | SRF Fusions Other Than With RELA Expand the Molecular Definition of SRF-fused Perivascular Tumors.
Karanian M, Kelsey A, Paindavoine S, Duc A, Vanacker H, Hook L, Weinbreck N, Delfour C, Minard V, Baillard P, Blay JY, Pissaloux D, Tirode F. | 01/16/2021 |
| Nuclear actin regulates cell proliferation and migration via inhibition of SRF and TEAD. | Nuclear actin regulates cell proliferation and migration via inhibition of SRF and TEAD.
McNeill MC, Wray J, Sala-Newby GB, Hindmarch CCT, Smith SA, Ebrahimighaei R, Newby AC, Bond M., Free PMC Article | 10/24/2020 |
| SRF-FOXO1 and SRF-NCOA1 gene fusion occurs in a subset of well differentiated rhabdomyosarcoma of the neck muscles. | SRF-FOXO1 and SRF-NCOA1 Fusion Genes Delineate a Distinctive Subset of Well-differentiated Rhabdomyosarcoma.
Karanian M, Pissaloux D, Gomez-Brouchet A, Chevenet C, Le Loarer F, Fernandez C, Minard V, Corradini N, Castex MP, Duc-Gallet A, Blay JY, Tirode F. | 08/1/2020 |
| Data show that transcription factor 21 (TCF21) directly interferes with formation and function of the myocardin (MYOCD)-serum response factor (SRF) complex. | Coronary Disease-Associated Gene TCF21 Inhibits Smooth Muscle Cell Differentiation by Blocking the Myocardin-Serum Response Factor Pathway.
Nagao M, Lyu Q, Zhao Q, Wirka RC, Bagga J, Nguyen T, Cheng P, Kim JB, Pjanic M, Miano JM, Quertermous T., Free PMC Article | 08/1/2020 |
| A dual luciferase reporter assay showed that both SRF mutants (G274D and G294C) impaired SRF transcriptional activity at the SRF promoter and atrial natriuretic factor (ANF) promoter (p < 0.05), additionally, the mutants displayed reduced synergism with GATA4. These results suggest that SRF-p.G274D and SRF-p.G294C may have potential pathogenic effects. | Novel mutations of the SRF gene in Chinese sporadic conotruncal heart defect patients.
Mengmeng X, Yuejuan X, Sun C, Yanan L, Fen L, Kun S., Free PMC Article | 07/18/2020 |
| Novel SRF-ICA1L Fusions in Cellular Myoid Neoplasms With Potential For Malignant Behavior | Novel SRF-ICA1L Fusions in Cellular Myoid Neoplasms With Potential For Malignant Behavior.
Suurmeijer AJ, Dickson BC, Swanson D, Sung YS, Zhang L, Antonescu CR., Free PMC Article | 05/9/2020 |
| Our findings indicate that overexpression of SRF may play an important role in human gastric cancer recurrence and prognosis. | Overexpression of serum response factor is correlated with poor prognosis in patients with gastric cancer.
Yin J, Lv X, Hu S, Zhao X, Liu Q, Xie H. | 11/30/2019 |
| Rnd3 is a MKL1-SRF target that plays a key role in the feedback loop described between the MKL1-SRF pathway and the organization of the actin cytoskeleton | Rnd3/RhoE expression is regulated by G-actin through MKL1-SRF signaling pathway.
Piquet L, Robbe T, Neaud V, Basbous S, Rosciglione S, Saltel F, Moreau V. | 09/21/2019 |
| 35 SRF/IGF2BP1-dependent genes showing conserved association with SRF and IGF2BP1 expression indicate a poor overall survival probability in ovarian, liver and lung cancer. In conclusion, these findings identify the SRF/IGF2BP1-, miRNome- and m6A-dependent control of gene expression as a conserved oncogenic driver network in cancer. | IGF2BP1 promotes SRF-dependent transcription in cancer in a m6A- and miRNA-dependent manner.
Müller S, Glaß M, Singh AK, Haase J, Bley N, Fuchs T, Lederer M, Dahl A, Huang H, Chen J, Posern G, Hüttelmaier S., Free PMC Article | 08/31/2019 |
| Data suggest that RBP-Jkappa protein (RBPJ) and serum response factor (SRF) cooperate to regulate gene expression in aortic smooth muscle cells (SMC). | RBPJ binds to consensus and methylated cis elements within phased nucleosomes and controls gene expression in human aortic smooth muscle cells in cooperation with SRF.
Rozenberg JM, Taylor JM, Mack CP., Free PMC Article | 08/17/2019 |
| Active serum response factor (SRF) along with its coactivator megakaryoblastic leukemia 1 (MKL1) binds DNA near hedgehog target genes and forms a previously unknown protein complex with the hedgehog transcription factor glioma-associated oncogene family zinc finger-1 (GLI1), causing amplification of GLI1 transcriptional activity. | Noncanonical hedgehog pathway activation through SRF-MKL1 promotes drug resistance in basal cell carcinomas.
Whitson RJ, Lee A, Urman NM, Mirza A, Yao CY, Brown AS, Li JR, Shankar G, Fry MA, Atwood SX, Lee EY, Hollmig ST, Aasi SZ, Sarin KY, Scott MP, Epstein EH Jr, Tang JY, Oro AE., Free PMC Article | 05/11/2019 |
| SRF may control cell proliferation and invasion by regulating Egr1 in cervical cancer. | Suppressing serum response factor inhibits invasion in cervical cancer cell lines via regulating Egr‑1 and epithelial-mesenchymal transition.
Ma L, Yu Y, Qu X. | 03/9/2019 |