| VEGF-induced Nrdp1 deficiency in vascular endothelial cells promotes cancer metastasis by degrading vascular basement membrane. | VEGF-induced Nrdp1 deficiency in vascular endothelial cells promotes cancer metastasis by degrading vascular basement membrane.
Li QQ, Guo M, He GH, Xi KH, Zhou MY, Shi RY, Chen GQ. | 06/20/2024 |
| Nrdp1-mediated Macrophage Phenotypic Regulation Promotes Functional Recovery in Mice with Mild Neurological Impairment after Intracerebral Hemorrhage. | Nrdp1-mediated Macrophage Phenotypic Regulation Promotes Functional Recovery in Mice with Mild Neurological Impairment after Intracerebral Hemorrhage.
Wu X, Chen Z, Chen Q, Lin C, Zheng X, Yuan B. | 05/22/2024 |
| Correlation between neuregulin receptor degradation protein-1 and Crohn's disease. | Correlation between neuregulin receptor degradation protein-1 and Crohn's disease.
Zong CY, Ji QQ, Chen FF, Yang JJ, Zhou H, Zhu BF, Zhou GX. | 04/12/2024 |
| Ubiquitin Ligase Nrdp1 Controls Autophagy-Associated Acrosome Biogenesis and Mitochondrial Arrangement during Spermiogenesis. | Ubiquitin Ligase Nrdp1 Controls Autophagy-Associated Acrosome Biogenesis and Mitochondrial Arrangement during Spermiogenesis.
Luo ZY, Jiang TX, Zhang T, Xu P, Qiu XB., Free PMC Article | 10/5/2023 |
| RNF41 orchestrates macrophage-driven fibrosis resolution and hepatic regeneration. | RNF41 orchestrates macrophage-driven fibrosis resolution and hepatic regeneration.
Moreno-Lanceta A, Medrano-Bosch M, Fundora Y, Perramón M, Aspas J, Parra-Robert M, Baena S, Fondevila C, Edelman ER, Jiménez W, Melgar-Lesmes P., Free PMC Article | 07/20/2023 |
| A20/Nrdp1 interaction alters the inflammatory signaling profile by mediating K48- and K63-linked polyubiquitination of effectors MyD88 and TBK1. | A20/Nrdp1 interaction alters the inflammatory signaling profile by mediating K48- and K63-linked polyubiquitination of effectors MyD88 and TBK1.
Meng Z, Xu R, Xie L, Wu Y, He Q, Gao P, He X, Chen Q, Xie Q, Zhang J, Yang Q., Free PMC Article | 08/28/2021 |
| RNF41 regulates the damage recognition receptor Clec9A and antigen cross-presentation in mouse dendritic cells. | RNF41 regulates the damage recognition receptor Clec9A and antigen cross-presentation in mouse dendritic cells.
Tullett KM, Tan PS, Park HY, Schittenhelm RB, Michael N, Li R, Policheni AN, Gruber E, Huang C, Fulcher AJ, Danne JC, Czabotar PE, Wakim LM, Mintern JD, Ramm G, Radford KJ, Caminschi I, O'Keeffe M, Villadangos JA, Wright MD, Blewitt ME, Heath WR, Shortman K, Purcell AW, Nicola NA, Zhang JG, Lahoud MH., Free PMC Article | 04/3/2021 |
| Data suggest that ring finger protein 41 Nrdp1 terminates T cell antigen receptors (TCRs) signaling by inactivating Zap70 kinase. | K33-linked polyubiquitination of Zap70 by Nrdp1 controls CD8(+) T cell activation.
Yang M, Chen T, Li X, Yu Z, Tang S, Wang C, Gu Y, Liu Y, Xu S, Li W, Zhang X, Wang J, Cao X. | 04/16/2016 |
| The novel Pdx1-Clec16a-Nrdp1 pathway this study describes provides a genetic basis for the pathogenesis of mitochondrial dysfunction in multiple forms of diabetes. | Diabetes Susceptibility Genes Pdx1 and Clec16a Function in a Pathway Regulating Mitophagy in β-Cells.
Soleimanpour SA, Ferrari AM, Raum JC, Groff DN, Yang J, Kaufman BA, Stoffers DA., Free PMC Article | 01/16/2016 |
| Nrdp1 may be a key mediator in the development of cardiac dysfunction after DOX treatment and associated with inhibition of Akt, ERK1/2 and STAT3. | Overexpression of Nrdp1 in the heart exacerbates doxorubicin-induced cardiac dysfunction in mice.
Zhang Y, Kang YM, Tian C, Zeng Y, Jia LX, Ma X, Du J, Li HH., Free PMC Article | 12/3/2011 |
| these results provide evidence for an important role for Nrdp1 in regulating ischemia/reperfusioninduced cardiac injury | Cardiac-specific overexpression of E3 ligase Nrdp1 increases ischemia and reperfusion-induced cardiac injury.
Zhang Y, Zeng Y, Wang M, Tian C, Ma X, Chen H, Fang Q, Jia L, Du J, Li H. | 07/16/2011 |
| Post-transcriptional mechanisms contribute to the suppression of the ErbB3 negative regulator protein Nrdp1 in mammary tumors. | Post-transcriptional mechanisms contribute to the suppression of the ErbB3 negative regulator protein Nrdp1 in mammary tumors.
Ingalla EQ, Miller JK, Wald JH, Workman HC, Kaur RP, Yen L, Fry WH, Borowsky AD, Young LJ, Sweeney C, Carraway KL 3rd., Free PMC Article | 10/23/2010 |
| Data suggest that Nrdp1 functions as both an adaptor protein and an E3 unbiquitin ligase to regulate TLR responses in different ways. | The E3 ubiquitin ligase Nrdp1 'preferentially' promotes TLR-mediated production of type I interferon.
Wang C, Chen T, Zhang J, Yang M, Li N, Xu X, Cao X. | 01/21/2010 |
| Rnf41 is nominated as a candidate gene for anxiety-like behaviors, depression, and vulnerability to seizures. | An E3 ubiquitin ligase, Really Interesting New Gene (RING) Finger 41, is a candidate gene for anxiety-like behavior and beta-carboline-induced seizures.
Kim S, Zhang S, Choi KH, Reister R, Do C, Baykiz AF, Gershenfeld HK., Free PMC Article | 01/21/2010 |