| MicroRNA-377-3p exacerbates chronic obstructive pulmonary disease through suppressing ZFP36L1 expression and inducing lung fibroblast senescence. | MicroRNA-377-3p exacerbates chronic obstructive pulmonary disease through suppressing ZFP36L1 expression and inducing lung fibroblast senescence.
Lu F, Yao LP, Gao DD, Alinejad T, Jiang XQ, Wu Q, Zhai QC, Liu M, Zhu SM, Qian MX, Xu LF, Chen CS, Zhang F., Free PMC Article | 03/11/2024 |
| ZFP36 ring finger protein like 1 significantly suppresses human coronavirus OC43 replication. | ZFP36 ring finger protein like 1 significantly suppresses human coronavirus OC43 replication.
Momin T, Villasenor A, Singh A, Darweesh M, Singh A, Rajput M., Free PMC Article | 03/2/2023 |
| ZFP36L1 Promotes Gastric Cancer Progression via Regulating JNK and p38 MAPK Signaling Pathways. | ZFP36L1 Promotes Gastric Cancer Progression via Regulating JNK and p38 MAPK Signaling Pathways.
Ding K, Zhang F, Qi G, Lin M, Chen M, Chen Y, Zheng J, Zhou F. | 12/17/2022 |
| Regulation of neuroendocrine plasticity by the RNA-binding protein ZFP36L1. | Regulation of neuroendocrine plasticity by the RNA-binding protein ZFP36L1.
Chen HY, Durmaz YT, Li Y, Sabet AH, Vajdi A, Denize T, Walton E, Laimon YN, Doench JG, Mahadevan NR, Losman JA, Barbie DA, Tolstorukov MY, Rudin CM, Sen T, Signoretti S, Oser MG., Free PMC Article | 09/3/2022 |
| Zinc Finger Protein ZFP36L1 Inhibits Flavivirus Infection by both 5'-3' XRN1 and 3'-5' RNA-Exosome RNA Decay Pathways. | Zinc Finger Protein ZFP36L1 Inhibits Flavivirus Infection by both 5'-3' XRN1 and 3'-5' RNA-Exosome RNA Decay Pathways.
Chiu H, Chiu HP, Yu HP, Lin LH, Chen ZP, Lin YL, Lin RJ., Free PMC Article | 02/26/2022 |
| ZFP36 Family Members Regulate the Proinflammatory Features of Psoriatic Dermal Fibroblasts. | ZFP36 Family Members Regulate the Proinflammatory Features of Psoriatic Dermal Fibroblasts.
Angiolilli C, Leijten EFA, Bekker CPJ, Eeftink E, Giovannone B, Nordkamp MO, van der Wal M, Thijs JL, Vastert SJ, van Wijk F, Radstake TRDJ, van Loosdregt J. | 02/5/2022 |
| ZFP36L1 plays an ambiguous role in the regulation of cell expansion and negatively regulates CDKN1A in chronic myeloid leukemia cells. | ZFP36L1 plays an ambiguous role in the regulation of cell expansion and negatively regulates CDKN1A in chronic myeloid leukemia cells.
Kaehler M, Dworschak M, Rodin JP, Ruemenapp J, Vater I, Penas EMM, Liu C, Cascorbi I, Nagel I. | 10/16/2021 |
| Overexpression of microRNA-129-5p in glioblastoma inhibits cell proliferation, migration, and colony-forming ability by targeting ZFP36L1. | Overexpression of microRNA-129-5p in glioblastoma inhibits cell proliferation, migration, and colony-forming ability by targeting ZFP36L1.
Guo X, Piao H, Zhang Y, Sun P, Yao B., Free PMC Article | 08/7/2021 |
| Nuclear accumulation of ZFP36L1 is cell cycle-dependent and determined by a C-terminal serine-rich cluster. | Nuclear accumulation of ZFP36L1 is cell cycle-dependent and determined by a C-terminal serine-rich cluster.
Matsuura Y, Noguchi A, Sakai S, Yokota N, Kawahara H. | 03/6/2021 |
| ARE-binding protein ZFP36L1 interacts with CNOT1 to directly repress translation via a deadenylation-independent mechanism. | ARE-binding protein ZFP36L1 interacts with CNOT1 to directly repress translation via a deadenylation-independent mechanism.
Otsuka H, Fukao A, Tomohiro T, Adachi S, Suzuki T, Takahashi A, Funakami Y, Natsume T, Yamamoto T, Duncan KE, Fujiwara T. | 01/16/2021 |
| Zinc finger protein ZFP36L1 inhibits influenza A virus through translational repression by targeting HA, M and NS RNA transcripts. | Zinc finger protein ZFP36L1 inhibits influenza A virus through translational repression by targeting HA, M and NS RNA transcripts.
Lin RJ, Huang CH, Liu PC, Lin IC, Huang YL, Chen AY, Chiu HP, Shih SR, Lin LH, Lien SP, Yen LC, Liao CL., Free PMC Article | 09/19/2020 |
| ZFP36L1 as a novel candidate tumor suppressor gene in myelofibrosis | Epigenomic profiling of myelofibrosis reveals widespread DNA methylation changes in enhancer elements and ZFP36L1 as a potential tumor suppressor gene that is epigenetically regulated.
Martínez-Calle N, Pascual M, Ordoñez R, Enériz ESJ, Kulis M, Miranda E, Guruceaga E, Segura V, Larráyoz MJ, Bellosillo B, Calasanz MJ, Besses C, Rifón J, Martín-Subero JI, Agirre X, Prosper F., Free PMC Article | 07/25/2020 |
| Study findings reveal an indispensable role of ZFP36L1 as a posttranscriptional safeguard against aberrant hypoxic signaling and abnormal cell-cycle progression. ZFP36L1 is significantly mutated and underexpressed in bladder cancer and reduction of ZFP36L1 expression was associated with worse survival in patients with breast cancer. | RNA-Binding Protein ZFP36L1 Suppresses Hypoxia and Cell-Cycle Signaling.
Loh XY, Sun QY, Ding LW, Mayakonda A, Venkatachalam N, Yeo MS, Silva TC, Xiao JF, Doan NB, Said JW, Ran XB, Zhou SQ, Dakle P, Shyamsunder P, Koh AP, Huang RY, Berman BP, Tan SY, Yang H, Lin DC, Koeffler HP. | 06/20/2020 |
| The results indicated that ZFP36L1 and ZFP36L2 play a negative role in cell proliferation; the underlying mechanisms might be mediated through a cyclin D-dependent and p53-independent pathway. | ZFP36L1 and ZFP36L2 inhibit cell proliferation in a cyclin D-dependent and p53-independent manner.
Suk FM, Chang CC, Lin RJ, Lin SY, Liu SC, Jau CF, Liang YC., Free PMC Article | 09/21/2019 |
| Study shows that the ZFP36 family member, ZFP36L1, is specifically upregulated in osteoarthritis (OA) chondrocytes and OA cartilage of humans and mice. ZFP36L1 regulates the mRNAs encoding two members of the HSP70 family that appear to exert protective effects on OA pathogenesis by inhibiting chondrocyte apoptosis. | RNA-binding protein ZFP36L1 regulates osteoarthritis by modulating members of the heat shock protein 70 family.
Son YO, Kim HE, Choi WS, Chun CH, Chun JS., Free PMC Article | 02/23/2019 |
| A ZFP36L1-mediated regulatory circuit through repressing CDK6 expression. | ZFP36L1 promotes monocyte/macrophage differentiation by repressing CDK6.
Chen MT, Dong L, Zhang XH, Yin XL, Ning HM, Shen C, Su R, Li F, Song L, Ma YN, Wang F, Zhao HL, Yu J, Zhang JW., Free PMC Article | 10/1/2016 |
| Gene expression analysis revealed that three gene BACH2, PTGER4 and ZFP36L1, are down-regulated in MS patients' blood cells compared to healthy subjects. | Anti-inflammatory genes associated with multiple sclerosis: a gene expression study.
Perga S, Montarolo F, Martire S, Berchialla P, Malucchi S, Bertolotto A. | 04/11/2015 |
| ZFP36L1 interacts with and mediates degradation of anti-apoptotic BCL2 mRNA as its important target in malignant B-cells. | Post-transcriptional regulation of BCL2 mRNA by the RNA-binding protein ZFP36L1 in malignant B cells.
Zekavati A, Nasir A, Alcaraz A, Aldrovandi M, Marsh P, Norton JD, Murphy JJ., Free PMC Article | 03/7/2015 |
| regulator of renal mineralocorticoid receptor abundance | Hypertonicity compromises renal mineralocorticoid receptor signaling through Tis11b-mediated post-transcriptional control.
Viengchareun S, Lema I, Lamribet K, Keo V, Blanchard A, Cherradi N, Lombès M., Free PMC Article | 12/20/2014 |
| NR4A2 expression is negatively regulated by zinc finger protein 36, C3H1 type-like 1 (Zfp36l1). | NR4A2 is regulated by gastrin and influences cellular responses of gastric adenocarcinoma cells.
Misund K, Selvik LK, Rao S, Nørsett K, Bakke I, Sandvik AK, Lægreid A, Bruland T, Prestvik WS, Thommesen L., Free PMC Article | 07/19/2014 |
| The roles of TTP and BRF proteins in regulated mRNA decay. | The roles of TTP and BRF proteins in regulated mRNA decay.
Sanduja S, Blanco FF, Dixon DA., Free PMC Article | 03/24/2012 |
| ZFP36L1 negatively regulates erythroid differentiation by directly binding the 3' untranslated region of Stat5b encoding mRNA. | ZFP36L1 negatively regulates erythroid differentiation of CD34+ hematopoietic stem cells by interfering with the Stat5b pathway.
Vignudelli T, Selmi T, Martello A, Parenti S, Grande A, Gemelli C, Zanocco-Marani T, Ferrari S., Free PMC Article | 01/22/2011 |
| these results suggest an important role of ZFP36L1 in wound healing. | ZFP36L1 is regulated by growth factors and cytokines in keratinocytes and influences their VEGF production.
Hacker C, Valchanova R, Adams S, Munz B. | 08/16/2010 |
| Von Hippel-Lindau gene product modulates TIS11B expression in renal cell carcinoma and has a role in vascular endothelial growth factor expression in hypoxia | Von Hippel-Lindau gene product modulates TIS11B expression in renal cell carcinoma: impact on vascular endothelial growth factor expression in hypoxia.
Sinha S, Dutta S, Datta K, Ghosh AK, Mukhopadhyay D., Free PMC Article | 01/21/2010 |
| Tis11b, an AU-rich binding protein induces apoptosis by rituximab in B cell chronic lymphocytic leukemia cells. | Involvement of Tis11b, an AU-rich binding protein, in induction of apoptosis by rituximab in B cell chronic lymphocytic leukemia cells.
Baou M, Jewell A, Muthurania A, Wickremasinghe RG, Yong KL, Carr R, Marsh P, Murphy JJ. | 01/21/2010 |