U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    STAT3 signal transducer and activator of transcription 3 [ Homo sapiens (human) ]

    Gene ID: 6774, updated on 1-Jul-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Overexpression of SOCS2 Inhibits EMT and M2 Macrophage Polarization in Cervical Cancer via IL-6/JAK2/STAT3 Pathway.

    Overexpression of SOCS2 Inhibits EMT and M2 Macrophage Polarization in Cervical Cancer via IL-6/JAK2/STAT3 Pathway.
    Li D, Huang Y, Wei M, Chen B, Lu Y.

    06/27/2024
    Circ_MAPK9 promotes STAT3 and LDHA expression by silencing miR-642b-3p and affects the progression of hepatocellular carcinoma.

    Circ_MAPK9 promotes STAT3 and LDHA expression by silencing miR-642b-3p and affects the progression of hepatocellular carcinoma.
    Wang K, Lu Q, Luo Y, Yu G, Wang Z, Lin J, Tan Z, Lao Y, Liu S, Yang H., Free PMC Article

    06/26/2024
    IDH2/R140Q mutation confers cytokine-independent proliferation of TF-1 cells by activating constitutive STAT3/5 phosphorylation.

    IDH2/R140Q mutation confers cytokine-independent proliferation of TF-1 cells by activating constitutive STAT3/5 phosphorylation.
    Yang J, Chen J, Chang J, Sun X, Wei Q, Cai X, Cao P., Free PMC Article

    06/24/2024
    Serine/Threonine kinase 16 phosphorylates STAT3 and confers a JAK2-Inhibition resistance phenotype in triple-negative breast cancer.

    Serine/Threonine kinase 16 phosphorylates STAT3 and confers a JAK2-Inhibition resistance phenotype in triple-negative breast cancer.
    Zhu Z, Xiang Q, Li S, Chen C, Shi J.

    06/21/2024
    Decreased HMGCS1 inhibits proliferation and inflammatory response of keratinocytes and ameliorates imiquimod-induced psoriasis via the STAT3/IL-23 axis.

    Decreased HMGCS1 inhibits proliferation and inflammatory response of keratinocytes and ameliorates imiquimod-induced psoriasis via the STAT3/IL-23 axis.
    Chen L, Huang D, Huang Z, Liu X, He M, Luo M, Tang Z, Tan G, Guo Q, Xiong H.

    06/18/2024
    STAT3 promotes cytoplasmic-nuclear translocation of RNA-binding protein HuR to inhibit IL-1beta-induced IL-8 production.

    STAT3 promotes cytoplasmic-nuclear translocation of RNA-binding protein HuR to inhibit IL-1β-induced IL-8 production.
    Long J, Zhao W, Xiang Y, Wang Y, Xiang W, Liu X, Jiang M, Song Y, Hu J.

    06/17/2024
    GBP1 promotes cutaneous squamous cell carcinoma proliferation and invasion through activation of STAT3 by SP1.

    GBP1 promotes cutaneous squamous cell carcinoma proliferation and invasion through activation of STAT3 by SP1.
    Yu S, Li Y, Feng W, Zeng J, Cui X, Zhou S, Zhang P.

    06/13/2024
    STAT3-induced lncRNA GNAS-AS1 accelerates keloid formation by mediating the miR-196a-5p/CXCL12/STAT3 axis in a feedback loop.

    STAT3-induced lncRNA GNAS-AS1 accelerates keloid formation by mediating the miR-196a-5p/CXCL12/STAT3 axis in a feedback loop.
    Liu Y, Ma TX, Fan PF, Wang Z, Wang Z, Li L.

    06/13/2024
    Splicing analysis of STAT3 tandem donor suggests non-canonical binding registers for U1 and U6 snRNAs.

    Splicing analysis of STAT3 tandem donor suggests non-canonical binding registers for U1 and U6 snRNAs.
    Kramárek M, Souček P, Réblová K, Grodecká LK, Freiberger T., Free PMC Article

    06/13/2024
    TSPAN6 reinforces the malignant progression of glioblastoma via interacting with CDK5RAP3 and regulating STAT3 signaling pathway.

    TSPAN6 reinforces the malignant progression of glioblastoma via interacting with CDK5RAP3 and regulating STAT3 signaling pathway.
    Zhang C, Du FH, Wang RX, Han WB, Lv X, Zeng LH, Chen GQ., Free PMC Article

    06/13/2024
    Daucosterol regulates JAK2-STAT3 signaling pathway to promote megakaryocyte differentiation.

    Daucosterol regulates JAK2-STAT3 signaling pathway to promote megakaryocyte differentiation.
    Zhang Z, Shang G, Lu Z, Hu J, Liu H, Lu T, Lu X.

    06/12/2024
    GGT1 is a SNP eQTL gene involved in STAT3 activation and associated with the development of Post-ERCP pancreatitis.

    GGT1 is a SNP eQTL gene involved in STAT3 activation and associated with the development of Post-ERCP pancreatitis.
    Furukawa R, Kuwatani M, Jiang JJ, Tanaka Y, Hasebe R, Murakami K, Tanaka K, Hirata N, Ohki I, Takahashi I, Yamasaki T, Shinohara Y, Nozawa S, Hojyo S, Kubota SI, Hashimoto S, Hirano S, Sakamoto N, Murakami M., Free PMC Article

    06/5/2024
    PLAU promotes cell proliferation and migration of head and neck cancer via STAT3 signaling pathway.

    PLAU promotes cell proliferation and migration of head and neck cancer via STAT3 signaling pathway.
    Cui X, Sun H, Liu X, Bai Y, Bai Y, Cui Y, Wang B, Zhang S, Li X.

    05/31/2024
    Pancreatic neuroendocrine tumor progression and resistance to everolimus: the crucial role of NF-kB and STAT3 interplay.

    Pancreatic neuroendocrine tumor progression and resistance to everolimus: the crucial role of NF-kB and STAT3 interplay.
    Vitali E, Valente G, Panzardi A, Laffi A, Zerbi A, Uccella S, Mazziotti G, Lania A.

    05/28/2024
    NRN1 interacts with Notch to increase oncogenic STAT3 signaling in melanoma.

    NRN1 interacts with Notch to increase oncogenic STAT3 signaling in melanoma.
    Devitt L, Westphal D, Pieger K, Schneider N, Bosserhoff AK, Kuphal S., Free PMC Article

    05/10/2024
    The endonuclease FEN1 mediates activation of STAT3 and facilitates proliferation and metastasis in breast cancer.

    The endonuclease FEN1 mediates activation of STAT3 and facilitates proliferation and metastasis in breast cancer.
    Wu M, Huang X, Wu B, Zhu M, Zhu Y, Yu L, Lan T, Liu J.

    05/7/2024
    KIAA0040 enhances glioma growth by controlling the JAK2/STAT3 signalling pathway.

    KIAA0040 enhances glioma growth by controlling the JAK2/STAT3 signalling pathway.
    He J, Xue K, Fan F, Li L, Rao X, Liu W, Nie C., Free PMC Article

    05/2/2024
    EZH2 Promotes Multiple Myeloma Progression via STAT3 Pathway Activation.

    EZH2 Promotes Multiple Myeloma Progression via STAT3 Pathway Activation.
    Wang Y, Tian J, Huang D, Gao Y, Lin H, Liu L, Wang A.

    04/30/2024
    Nuclear autoantigenic sperm protein facilitates glioblastoma progression and radioresistance by regulating the ANXA2/STAT3 axis.

    Nuclear autoantigenic sperm protein facilitates glioblastoma progression and radioresistance by regulating the ANXA2/STAT3 axis.
    Qiu Y, Pei D, Wang M, Wang Q, Duan W, Wang L, Liu K, Guo Y, Luo L, Guo Z, Guan F, Wang Z, Xing A, Liu Z, Ma Z, Jiang G, Yan D, Liu X, Zhang Z, Wang W., Free PMC Article

    04/29/2024
    The binding of PKCepsilon and MEG2 to STAT3 regulates IL-6-mediated microglial hyperalgesia during inflammatory pain.

    The binding of PKCε and MEG2 to STAT3 regulates IL-6-mediated microglial hyperalgesia during inflammatory pain.
    Li X, Wang J, Liao C, Yang X, Zhao Z, Liu Y, Xue Q, Luo Y, Liu X, Liu Z.

    04/26/2024
    Targeting C21orf58 is a Novel Treatment Strategy of Hepatocellular Carcinoma by Disrupting the Formation of JAK2/C21orf58/STAT3 Complex.

    Targeting C21orf58 is a Novel Treatment Strategy of Hepatocellular Carcinoma by Disrupting the Formation of JAK2/C21orf58/STAT3 Complex.
    Jiang H, Wang Y, Wen D, Yu R, Esa SS, Lv K, Feng Q, Liu J, Li F, He L, Di X, Zhang S., Free PMC Article

    04/23/2024
    ITGA2 as a prognostic factor of glioma promotes GSCs invasion and EMT by activating STAT3 phosphorylation.

    ITGA2 as a prognostic factor of glioma promotes GSCs invasion and EMT by activating STAT3 phosphorylation.
    Zhang J, Li R, Zhang H, Wang S, Zhao Y.

    04/23/2024
    ANXA9 facilitates S100A4 and promotes breast cancer progression through modulating STAT3 pathway.

    ANXA9 facilitates S100A4 and promotes breast cancer progression through modulating STAT3 pathway.
    Zhou X, Zhao J, Yan T, Ye D, Wang Y, Zhou B, Liu D, Wang X, Zheng W, Zheng B, Qian F, Li Y, Li D, Fang L., Free PMC Article

    04/17/2024
    Entero-toxigenic Bacteroides fragilis contributes to intestinal barrier injury and colorectal cancer progression by mediating the BFT/STAT3/ZEB2 pathway.

    Entero-toxigenic Bacteroides fragilis contributes to intestinal barrier injury and colorectal cancer progression by mediating the BFT/STAT3/ZEB2 pathway.
    Yang J, Wang X, Hu T, Huang H, Chen G, Jin B, Zeng G, Liu J., Free PMC Article

    04/17/2024
    STAT3 is a genetic modifier of TGF-beta induced EMT in KRAS mutant pancreatic cancer.

    STAT3 is a genetic modifier of TGF-beta induced EMT in KRAS mutant pancreatic cancer.
    D'Amico S, Kirillov V, Petrenko O, Reich NC., Free PMC Article

    04/12/2024
    firstprevious page of 130 nextlast