Association of SULT1A2 rs1059491 with obesity and dyslipidaemia in southern Chinese adults. | Association of SULT1A2 rs1059491 with obesity and dyslipidaemia in southern Chinese adults. Lv HY, Shi G, Li C, Ye YF, Chen YH, Chen LH, Tung TH, Zhang M., Free PMC Article | 05/8/2023 |
Suggest SULT1A1/1A2 play a central role in furfuryl alcohol bioactivation and the formation of hemoglobin adducts. | Hemoglobin adducts of furfuryl alcohol in genetically modified mouse models: Role of endogenous sulfotransferases 1a1 and 1d1 and transgenic human sulfotransferases 1A1/1A2. Monien BH, Sachse B, Meinl W, Abraham K, Lampen A, Glatt H. | 09/1/2018 |
The polymorphism of SULT1A2*2 is not associated with esophageal squamous cell carcinoma risk. | Genotypes of CYP1A1, SULT1A1 and SULT1A2 and risk of squamous cell carcinoma of esophagus: outcome of a case-control study from Kashmir, India. Shah IA, Bhat GA, Mehta P, Lone MM, Dar NA. | 05/6/2017 |
It metabolizes breast cancer drugs like afimoxifene and endoxifen by sulfation. | Sulfation of afimoxifene, endoxifen, raloxifene, and fulvestrant by the human cytosolic sulfotransferases (SULTs): A systematic analysis. Hui Y, Luo L, Zhang L, Kurogi K, Zhou C, Sakakibara Y, Suiko M, Liu MC. | 05/14/2016 |
SULT1A2 genotype also seems to play an important role in maintaining optimal levels of both 4OH-TAM and endoxifen. | Relationship between genotypes Sult1a2 and Cyp2d6 and tamoxifen metabolism in breast cancer patients. Fernández-Santander A, Gaibar M, Novillo A, Romero-Lorca A, Rubio M, Chicharro LM, Tejerina A, Bandrés F., Free PMC Article | 08/23/2014 |
resequenced the SULT1A2 and SULT1A2 genes and identified 51 variations in ethnic Koreans, including 9 that were previously unknown. Allele frequencies, haplotype structures, LD blocks, and haplotype-tagging SNPs were determined. | Single nucleotide polymorphisms in SULT1A1 and SULT1A2 in a Korean population. Lee SJ, Kim WY, Jarrar YB, Kim YW, Lee SS, Shin JG. | 05/3/2014 |
the statistical hypothesis that SULT1A1 and SULT1A2 alleles are independently distributed was rejected; a strongly positive linkage was detected between SULT1A1*2 and SULT1A2*2 alleles in Turkey population | Genetic polymorphisms of sulfotransferases (SULT1A1 and SULT1A2) in a Turkish population. Arslan S, Arslan S. | 03/26/2011 |
the structures of SULT1A2 and an allozyme of SULT1A1, SULT1A1 *3, bound with 3'-phosphoadenosine 5'-phosphate at 2.4 and 2.3A resolution, respectively, were determined. | Crystal structures of SULT1A2 and SULT1A1 *3: insights into the substrate inhibition and the role of Tyr149 in SULT1A2. Lu J, Li H, Zhang J, Li M, Liu MY, An X, Liu MC, Chang W. | 07/12/2010 |
SULT1A1/SULT1A2 gene complex showed suggestive haplotypic association in the family-based cardiovascular disease study, with the greatest increase in risk conferred by the SULT1A2 235T allele | Genetic polymorphisms in platelet-related proteins and coronary artery disease: investigation of candidate genes, including N-acetylgalactosaminyltransferase 4 (GALNT4) and sulphotransferase 1A1/2 (SULT1A1/2). O'Halloran AM, Patterson CC, Horan P, Maree A, Curtin R, Stanton A, McKeown PP, Shields DC, O'Halloran AM, Patterson CC, Horan P, Maree A, Curtin R, Stanton A, McKeown PP, Shields DC. | 01/21/2010 |
Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) | Low-penetrance alleles predisposing to sporadic colorectal cancers: a French case-controlled genetic association study. Küry S, Buecher B, Robiou-du-Pont S, Scoul C, Colman H, Le Neel T, Le Houérou C, Faroux R, Ollivry J, Lafraise B, Chupin LD, Sébille V, Bézieau S., Free PMC Article | 03/25/2009 |
Observational study of gene-disease association. (HuGE Navigator) | See all PubMed (9) articlesEvaluation of candidate genes for cholinesterase activity in farmworkers exposed to organophosphorus pesticides: association of single nucleotide polymorphisms in BCHE. Howard TD, Hsu FC, Grzywacz JG, Chen H, Quandt SA, Vallejos QM, Whalley LE, Cui W, Padilla S, Arcury TA. Genetic variation in the estrogen metabolic pathway and mammographic density as an intermediate phenotype of breast cancer. Li J, Eriksson L, Humphreys K, Czene K, Liu J, Tamimi RM, Lindström S, Hunter DJ, Vachon CM, Couch FJ, Scott CG, Lagiou P, Hall P. Genetic susceptibility to distinct bladder cancer subphenotypes. Guey LT, García-Closas M, Murta-Nascimento C, Lloreta J, Palencia L, Kogevinas M, Rothman N, Vellalta G, Calle ML, Marenne G, Tardón A, Carrato A, García-Closas R, Serra C, Silverman DT, Chanock S, Real FX, Malats N, EPICURO/Spanish Bladder Cancer Study investigators. Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects. Saito A, Kawamoto M, Kamatani N. Bladder cancer risk and genetic variation in AKR1C3 and other metabolizing genes. Figueroa JD, Malats N, García-Closas M, Real FX, Silverman D, Kogevinas M, Chanock S, Welch R, Dosemeci M, Lan Q, Tardón A, Serra C, Carrato A, García-Closas R, Castaño-Vinyals G, Rothman N. Genetic polymorphisms in platelet-related proteins and coronary artery disease: investigation of candidate genes, including N-acetylgalactosaminyltransferase 4 (GALNT4) and sulphotransferase 1A1/2 (SULT1A1/2). O'Halloran AM, Patterson CC, Horan P, Maree A, Curtin R, Stanton A, McKeown PP, Shields DC, O'Halloran AM, Patterson CC, Horan P, Maree A, Curtin R, Stanton A, McKeown PP, Shields DC. The relationship among the polymorphisms of SULT1A1, 1A2 and different types of cancers in Taiwanese. Peng CT, Chen JC, Yeh KT, Wang YF, Hou MF, Lee TP, Shih MC, Chang JY, Chang JG, Peng CT, Chen JC, Yeh KT, Wang YF, Hou MF, Lee TP, Shih MC, Chang JY, Chang JG. A pharmacogenetic study to investigate the role of dietary carcinogens in the etiology of colorectal cancer. Sachse C, Smith G, Wilkie MJ, Barrett JH, Waxman R, Sullivan F, Forman D, Bishop DT, Wolf CR, Colorectal Cancer Study Group. Sulfotransferase 1A2*2 is a risk factor for early-onset breast cancer. Hou MF, Chen ST, Chen JC, Yeh KT, Lee TP, Chen CM, Shih MC, Lin CC, Chang JG, Hou MF, Chen ST, Chen JC, Yeh KT, Lee TP, Chen CM, Shih MC, Lin CC, Chang JG. | 03/13/2008 |
Observational study of genotype prevalence. (HuGE Navigator) | See all PubMed (3) articlesGenetic polymorphisms of sulfotransferases (SULT1A1 and SULT1A2) in a Turkish population. Arslan S, Arslan S. Genetic polymorphisms and linkage disequilibrium of sulfotransferase SULT1A1 and SULT1A2 in a Korean population: comparison of other ethnic groups. Kim KA, Lee SY, Park PW, Ha JM, Park JY, Kim KA, Lee SY, Park PW, Ha JM, Park JY. Sulfation pharmacogenetics: SULT1A1 and SULT1A2 allele frequencies in Caucasian, Chinese and African-American subjects. Carlini EJ, Raftogianis RB, Wood TC, Jin F, Zheng W, Rebbeck TR, Weinshilboum RM. | 03/13/2008 |
SULT1A1*2 and SULT1A2*2 are the major allelic variants in the Korean population | Genetic polymorphisms and linkage disequilibrium of sulfotransferase SULT1A1 and SULT1A2 in a Korean population: comparison of other ethnic groups. Kim KA, Lee SY, Park PW, Ha JM, Park JY, Kim KA, Lee SY, Park PW, Ha JM, Park JY. | 01/21/2010 |
SULT1A2 polymorphisms in 230 Taiwanese breast cancer patients | Sulfotransferase 1A2*2 is a risk factor for early-onset breast cancer. Hou MF, Chen ST, Chen JC, Yeh KT, Lee TP, Chen CM, Shih MC, Lin CC, Chang JG, Hou MF, Chen ST, Chen JC, Yeh KT, Lee TP, Chen CM, Shih MC, Lin CC, Chang JG. | 01/21/2010 |
the relationship among the polymorphisms of this enzyme and SULT1A1 in different types of cancers in Taiwanese | The relationship among the polymorphisms of SULT1A1, 1A2 and different types of cancers in Taiwanese. Peng CT, Chen JC, Yeh KT, Wang YF, Hou MF, Lee TP, Shih MC, Chang JY, Chang JG, Peng CT, Chen JC, Yeh KT, Wang YF, Hou MF, Lee TP, Shih MC, Chang JY, Chang JG. | 01/21/2010 |