| LINC01140 inhibits nonsmall cell lung cancer progression and cisplatin resistance through the miR-4742-5p/TACC1 axis. | LINC01140 inhibits nonsmall cell lung cancer progression and cisplatin resistance through the miR-4742-5p/TACC1 axis.
Wang Y, Li M, Zhang L, Chen Y, Ha M. | 07/23/2022 |
| Neurofibrosarcoma Revisited: An Institutional Case Series of Uterine Sarcomas Harboring Kinase-related Fusions With Report of a Novel FGFR1-TACC1 Fusion. | Neurofibrosarcoma Revisited: An Institutional Case Series of Uterine Sarcomas Harboring Kinase-related Fusions With Report of a Novel FGFR1-TACC1 Fusion.
Devereaux KA, Weiel JJ, Mills AM, Kunder CA, Longacre TA. | 05/15/2021 |
| The correlation between TACC1 expression and HER-2-positive status indicates synergistic regulation of these two prognostic markers in gastric carcinoma patients. | Prognosis significance of HER2 status and TACC1 expression in patients with gastric carcinoma.
Lv J, Yao YS, Zhou F, Zhuang LK, Yao RY, Liang J, Qiu WS, Yue L. | 10/24/2015 |
| TFF3 and TACC1 over-expression in epithelial cells of surgically resected gastric cancer tissues was an independent predictor of short survival in gastric cancer patients. | Impact of NPM, TFF3 and TACC1 on the prognosis of patients with primary gastric cancer.
Ding A, Zhao W, Shi X, Yao R, Zhou F, Yue L, Liu S, Qiu W., Free PMC Article | 10/4/2014 |
| These findings provide proof and the foundation for the molecular and biological relationships of ErbB-2 and TACC1 in breast cancer. | Efficient downregulation of ErbB-2 induces TACC1 upregulation in breast cancer cell lines.
Xiang J, Qiu W, Wang X, Zhou F, Wang Z, Liu S, Yue L. | 09/14/2013 |
| study reports that a small subset of glioblastoma multiforme tumors harbors oncogenic chromosomal translocations that fuse in-frame the tyrosine kinase coding domains of fibroblast growth factor receptor genes(FGFR1 or FGFR3) to the transforming acidic coiled-coil coding domains of TACC1 or TACC3; the FGFR-TACC fusion protein displays oncogenic activity | Transforming fusions of FGFR and TACC genes in human glioblastoma.
Singh D, Chan JM, Zoppoli P, Niola F, Sullivan R, Castano A, Liu EM, Reichel J, Porrati P, Pellegatta S, Qiu K, Gao Z, Ceccarelli M, Riccardi R, Brat DJ, Guha A, Aldape K, Golfinos JG, Zagzag D, Mikkelsen T, Finocchiaro G, Lasorella A, Rabadan R, Iavarone A., Free PMC Article | 11/24/2012 |
| the study demonstrated that TACC1 localizes at the midbody during cytokinesis and interacts with and is a substrate of Aurora-C, which warrant further investigation in order to elucidate the functional significance of this interaction. | Aurora-C interacts with and phosphorylates the transforming acidic coiled-coil 1 protein.
Gabillard JC, Ulisse S, Baldini E, Sorrenti S, Cremet JY, Coccaro C, Prigent C, D'Armiento M, Arlot-Bonnemains Y. | 08/6/2011 |
| Observational study of gene-disease association. (HuGE Navigator) | See all PubMed (2) articlesA large-scale candidate gene association study of age at menarche and age at natural menopause.
He C, Kraft P, Chasman DI, Buring JE, Chen C, Hankinson SE, Paré G, Chanock S, Ridker PM, Hunter DJ. Centrosome-related genes, genetic variation, and risk of breast cancer.
Olson JE, Wang X, Pankratz VS, Fredericksen ZS, Vachon CM, Vierkant RA, Cerhan JR, Couch FJ. | 06/30/2010 |
| TACC1 depletion in the cell led to decreased RARalpha and TRalpha ligand-dependent transcriptional activity and to delocalization of TR from the nucleus to the cytoplasm. | The transforming acidic coiled coil (TACC1) protein modulates the transcriptional activity of the nuclear receptors TR and RAR.
Guyot R, Vincent S, Bertin J, Samarut J, Ravel-Chapuis P., Free PMC Article | 05/31/2010 |
| TACC1 and a three-gene expression signature (TACC1, NOV, and PTTG1) were identified as independent prognostic markers. | Identification of TACC1, NOV, and PTTG1 as new candidate genes associated with endocrine therapy resistance in breast cancer.
Ghayad SE, Vendrell JA, Bieche I, Spyratos F, Dumontet C, Treilleux I, Lidereau R, Cohen PA. | 01/21/2010 |
| Splice variants can be localized to different subcellular compartments in a cell-and tissue-specific manner. | Temporal and spatial expression of TACC1 in the mouse and human.
Lauffart B, Dimatteo A, Vaughan MM, Cincotta MA, Black JD, Still IH. | 01/21/2010 |
| Interaction of the transforming acidic coiled-coil 1 (TACC1) protein with ch-TOG and GAS41/NuBI1 suggests multiple TACC1-containing protein complexes in human cells | Interaction of the transforming acidic coiled-coil 1 (TACC1) protein with ch-TOG and GAS41/NuBI1 suggests multiple TACC1-containing protein complexes in human cells.
Lauffart B, Howell SJ, Tasch JE, Cowell JK, Still IH., Free PMC Article | 01/21/2010 |
| Down regulation of tacc1 controls mrna homeostasis in polarized cells and participates in oncogenic processes in human cancers | Carcinogenesis and translational controls: TACC1 is down-regulated in human cancers and associates with mRNA regulators.
Conte N, Charafe-Jauffret E, Delaval B, Adélaïde J, Ginestier C, Geneix J, Isnardon D, Jacquemier J, Birnbaum D. | 01/21/2010 |
| Splicing pattern of its mRNA is altered in stomach cancer | Altered splicing pattern of TACC1 mRNA in gastric cancer.
Line A, Slucka Z, Stengrevics A, Li G, Rees RC. | 01/21/2010 |
| REVIEW: genetics, expression, gene expression regulation, and function studies | AINT/ERIC/TACC: an expanding family of proteins with C-terminal coiled coil domains.
Lappin TR, Mullan RN, Stewart JP, Morgan NA, Thompson A, Maxwell AP. | 01/21/2010 |
| TACC1 and the mitotic kinase Aurora B belong to the same complex during cytokinesis. | Aurora B -TACC1 protein complex in cytokinesis.
Delaval B, Ferrand A, Conte N, Larroque C, Hernandez-Verdun D, Prigent C, Birnbaum D. | 01/21/2010 |