| Hierarchical TAF1-dependent co-translational assembly of the basal transcription factor TFIID. | Hierarchical TAF1-dependent co-translational assembly of the basal transcription factor TFIID.
Bernardini A, Mukherjee P, Scheer E, Kamenova I, Antonova S, Mendoza Sanchez PK, Yayli G, Morlet B, Timmers HTM, Tora L., Free PMC Article | 08/25/2023 |
| MIAT shuttled by tumor-secreted exosomes promotes paclitaxel resistance in esophageal cancer cells by activating the TAF1/SREBF1 axis. | MIAT shuttled by tumor-secreted exosomes promotes paclitaxel resistance in esophageal cancer cells by activating the TAF1/SREBF1 axis.
Zhang S, Zhong J, Guo D, Zhang S, Huang G, Chen Y, Xu C, Chen W, Zhang Q, Zhao C, Liu S, Luo Z, Lin C. | 08/22/2023 |
| TAF1 bromodomain inhibition as a candidate epigenetic driver of congenital heart disease. | TAF1 bromodomain inhibition as a candidate epigenetic driver of congenital heart disease.
Leigh RS, Välimäki MJ, Kaynak BL, Ruskoaho HJ. | 05/13/2023 |
| TAF1 promotes NSCLC cell epithelial-mesenchymal transition by transcriptionally activating TGFbeta1. | TAF1 promotes NSCLC cell epithelial-mesenchymal transition by transcriptionally activating TGFβ1.
Zhang J, Li R, Zhang B, Cui X. | 11/29/2022 |
| Differential dependencies of human RNA polymerase II promoters on TBP, TAF1, TFIIB and XPB. | Differential dependencies of human RNA polymerase II promoters on TBP, TAF1, TFIIB and XPB.
Santana JF, Collins GS, Parida M, Luse DS, Price DH., Free PMC Article | 11/19/2022 |
| Elucidating Hexanucleotide Repeat Number and Methylation within the X-Linked Dystonia-Parkinsonism (XDP)-Related SVA Retrotransposon in TAF1 with Nanopore Sequencing. | Elucidating Hexanucleotide Repeat Number and Methylation within the X-Linked Dystonia-Parkinsonism (XDP)-Related SVA Retrotransposon in TAF1 with Nanopore Sequencing.
Lüth T, Laβ J, Schaake S, Wohlers I, Pozojevic J, Jamora RDG, Rosales RL, Brüggemann N, Saranza G, Diesta CCE, Schlüter K, Tse R, Reyes CJ, Brand M, Busch H, Klein C, Westenberger A, Trinh J., Free PMC Article | 02/26/2022 |
| Yeast Bromodomain Factor 1 and Its Human Homolog TAF1 Play Conserved Roles in Promoting Homologous Recombination. | Yeast Bromodomain Factor 1 and Its Human Homolog TAF1 Play Conserved Roles in Promoting Homologous Recombination.
Peng H, Zhang S, Peng Y, Zhu S, Zhao X, Zhao X, Yang S, Liu G, Dong Y, Gan X, Li Q, Zhang X, Pei H, Chen X., Free PMC Article | 01/22/2022 |
| Template activating factor-I epigenetically regulates the TERT transcription in human cancer cells. | Template activating factor-I epigenetically regulates the TERT transcription in human cancer cells.
Kato K, Kawaguchi A, Nagata K., Free PMC Article | 11/13/2021 |
| Congenital Heart Defects Due to TAF1 Missense Variants. | Congenital Heart Defects Due to TAF1 Missense Variants.
Morton SU, Agarwal R, Madden JA, Genetti CA, Brownstein CA, López-Giráldez F, Choi J, Seidman CE, Seidman JG, Lyon GJ, Agrawal PB., Free PMC Article | 08/21/2021 |
| TAF1 Transcripts and Neurofilament Light Chain as Biomarkers for X-linked Dystonia-Parkinsonism. | TAF1 Transcripts and Neurofilament Light Chain as Biomarkers for X-linked Dystonia-Parkinsonism.
Al Ali J, Vaine CA, Shah S, Campion L, Hakoum A, Supnet ML, Acuña P, Aldykiewicz G, Multhaupt-Buell T, Ganza NGM, Lagarde JBB, De Guzman JK, Go C, Currall B, Trombetta B, Webb PK, Talkowski M, Arnold SE, Cheah PS, Ito N, Sharma N, Bragg DC, Ozelius L, Breakefield XO., Free PMC Article | 05/1/2021 |
| SVA insertion in X-linked Dystonia Parkinsonism alters histone H3 acetylation associated with TAF1 gene. | SVA insertion in X-linked Dystonia Parkinsonism alters histone H3 acetylation associated with TAF1 gene.
Petrozziello T, Dios AM, Mueller KA, Vaine CA, Hendriks WT, Glajch KE, Mills AN, Mangkalaphiban K, Penney EB, Ito N, Fernandez-Cerado C, Legarda GPA, Velasco-Andrada MS, Acuña PJ, Ang MA, Muñoz EL, Diesta CCE, Macalintal-Canlas R, Acuña G, Sharma N, Ozelius LJ, Bragg DC, Sadri-Vakili G., Free PMC Article | 02/2/2021 |
| Pathogenic SREK1 decrease in Huntington's disease lowers TAF1 mimicking X-linked dystonia parkinsonism. | Pathogenic SREK1 decrease in Huntington's disease lowers TAF1 mimicking X-linked dystonia parkinsonism.
Hernández IH, Cabrera JR, Santos-Galindo M, Sánchez-Martín M, Domínguez V, García-Escudero R, Pérez-Álvarez MJ, Pintado B, Lucas JJ., Free PMC Article | 01/2/2021 |
| SET/TAF1 forms a distance-dependent feedback loop with Aurora B and Bub1 as a tension sensor at centromeres. | SET/TAF1 forms a distance-dependent feedback loop with Aurora B and Bub1 as a tension sensor at centromeres.
Asai Y, Matsumura R, Hasumi Y, Susumu H, Nagata K, Watanabe Y, Terada Y., Free PMC Article | 12/26/2020 |
| Identification of TAF1, SAT1, and ARHGEF9 as DNA methylation biomarkers for hepatocellular carcinoma. | Identification of TAF1, SAT1, and ARHGEF9 as DNA methylation biomarkers for hepatocellular carcinoma.
Cai C, Xie X, Zhou J, Fang X, Wang F, Wang M. | 08/29/2020 |
| The Thr325Ile polymorphism, but no Ala147Thr polymorphism in TAF1 gene is associated with ST acute myocardial infarction. | Genetic Polymorphisms Associated with Thrombotic Disease Comparison of Two Territories: Myocardial Infarction and Ischemic Stroke.
Isordia-Salas I, Martínez-Marino M, Alberti-Minutti P, Ricardo-Moreno MT, Castro-Calvo R, Santiago-Germán D, Alvarado-Moreno JA, Calleja-Carreño C, Hernández-Juárez J, Leaños-Miranda A, Majluf-Cruz A., Free PMC Article | 05/2/2020 |
| Liver fibrosis caused by hepatitis C virus results in altered hepatic expression of TAF1. | Identification of TAF1, HNF4A, and CALM2 as potential therapeutic target genes for liver fibrosis.
Ji D, Chen GF, Wang JC, Cao LH, Lu F, Mu XX, Zhang XY, Lu XJ. | 04/25/2020 |
| Repeat number showed significant inverse correlations with age-at-onset and with TAF1 expression and a positive correlation with parkinsonism disease severity and cognitive dysfunction. | A hexanucleotide repeat modifies expressivity of X-linked dystonia parkinsonism.
Westenberger A, Reyes CJ, Saranza G, Dobricic V, Hanssen H, Domingo A, Laabs BH, Schaake S, Pozojevic J, Rakovic A, Grütz K, Begemann K, Walter U, Dressler D, Bauer P, Rolfs A, Münchau A, Kaiser FJ, Ozelius LJ, Jamora RD, Rosales RL, Diesta CCE, Lohmann K, König IR, Brüggemann N, Klein C. | 04/4/2020 |
| These findings reveal a role of TAF1 in leukemogenesis and identify TAF1 as a potential therapeutic target for AML1-ETO -expressing leukemia. | TAF1 plays a critical role in AML1-ETO driven leukemogenesis.
Xu Y, Man N, Karl D, Martinez C, Liu F, Sun J, Martinez CJ, Martin GM, Beckedorff F, Lai F, Yue J, Roisman A, Greenblatt S, Duffort S, Wang L, Sun X, Figueroa M, Shiekhattar R, Nimer S., Free PMC Article | 02/29/2020 |
| Our findings highlight the regulatory networks among TFs, lncRNAs, miRNAs, and mRNAs in hepatocellular carcinoma (HCC). Several key molecules, such as hsa-miR-195, lncRNA MALAT1 and TFs TAF1 and HNF4alpha, may contribute to the progression of HCC. | Identification of potential transcription factors, long noncoding RNAs, and microRNAs associated with hepatocellular carcinoma.
Yan H, Wang Q, Shen Q, Li Z, Tian J, Jiang Q, Gao L. | 11/3/2018 |
| These data directly link sequence variation within the XDP-specific SVA sequence to phenotypic variability in clinical disease manifestation and provide insight into potential mechanisms by which this intronic retroelement may induce transcriptional interference in TAF1 expression. | Disease onset in X-linked dystonia-parkinsonism correlates with expansion of a hexameric repeat within an SVA retrotransposon in TAF1.
Bragg DC, Mangkalaphiban K, Vaine CA, Kulkarni NJ, Shin D, Yadav R, Dhakal J, Ton ML, Cheng A, Russo CT, Ang M, Acuña P, Go C, Franceour TN, Multhaupt-Buell T, Ito N, Müller U, Hendriks WT, Breakefield XO, Sharma N, Ozelius LJ., Free PMC Article | 07/7/2018 |
| present a case study where a combination of experimental techniques and computational simulations was used to comprehensively characterize the binding and structure-affinity relationships for a series of Bromosporine-based bivalent bromodomain ligands with a bivalent protein, Transcription Initiation Factor TFIID subunit 1 (TAF1). | Quantitative Characterization of Bivalent Probes for a Dual Bromodomain Protein, Transcription Initiation Factor TFIID Subunit 1.
Suh JL, Watts B, Stuckey JI, Norris-Drouin JL, Cholensky SH, Dickson BM, An Y, Mathea S, Salah E, Knapp S, Khan A, Adams AT, Strahl BD, Sagum CA, Bedford MT, James LI, Kireev DB, Frye SV., Free PMC Article | 05/12/2018 |
| The results converge on TAF1 dysfunction in peripheral models of X-linked dystonia-parkinsonism, and provide evidence of altered expression of a canonical gene in this disease. Furthermore, this study illustrates a link between the previously described genetic alterations and TAF1 dysfunction at the transcriptome level. | Evidence of TAF1 dysfunction in peripheral models of X-linked dystonia-parkinsonism.
Domingo A, Amar D, Grütz K, Lee LV, Rosales R, Brüggemann N, Jamora RD, Cutiongco-Dela Paz E, Rolfs A, Dressler D, Walter U, Krainc D, Lohmann K, Shamir R, Klein C, Westenberger A., Free PMC Article | 08/5/2017 |
| TAF1 and TAF1L genes harbored not only somatic mutations but also mutational ITH. | Frameshift Mutations in the Mononucleotide Repeats of TAF1 and TAF1L Genes in Gastric and Colorectal Cancers with Regional Heterogeneity.
Oh HR, An CH, Yoo NJ, Lee SH. | 03/25/2017 |
| N-TAF1 expression is impaired in X-linked dystonia-parkinsonism. | Decreased N-TAF1 expression in X-linked dystonia-parkinsonism patient-specific neural stem cells.
Ito N, Hendriks WT, Dhakal J, Vaine CA, Liu C, Shin D, Shin K, Wakabayashi-Ito N, Dy M, Multhaupt-Buell T, Sharma N, Breakefield XO, Bragg DC., Free PMC Article | 12/31/2016 |
| The bromodomains of BRD9, CECR2, and the second bromodomain of TAF1 recognize the longer butyryl mark on histones. In addition, the TAF1 second bromodomain is capable of binding crotonyl marks. | A Subset of Human Bromodomains Recognizes Butyryllysine and Crotonyllysine Histone Peptide Modifications.
Flynn EM, Huang OW, Poy F, Oppikofer M, Bellon SF, Tang Y, Cochran AG. | 07/30/2016 |