| SETD7 Promotes Cell Proliferation and Migration via Methylation-mediated TAF7 in Clear Cell Renal Cell Carcinoma. | SETD7 Promotes Cell Proliferation and Migration via Methylation-mediated TAF7 in Clear Cell Renal Cell Carcinoma.
Zhang J, Duan B, Li F, Jing X, Li R, Cai S, Cao L, Jiang Q, Zhou J, Zhou J, Qin Y, Wang X, Tong D, Huang C., Free PMC Article | 10/29/2024 |
| Novel variations in spermatogenic transcription regulators RFX2 and TAF7 increase risk of azoospermia. | Novel variations in spermatogenic transcription regulators RFX2 and TAF7 increase risk of azoospermia.
Pal S, Paladhi P, Dutta S, Bose G, Ghosh P, Chattopadhyay R, Chakravarty B, Saha I, Ghosh S., Free PMC Article | 03/19/2022 |
| MicroRNA-374c-5p inhibits the development of breast cancer through TATA-box binding protein associated factor 7-mediated transcriptional regulation of DEP domain containing 1. | MicroRNA-374c-5p inhibits the development of breast cancer through TATA-box binding protein associated factor 7-mediated transcriptional regulation of DEP domain containing 1.
Hao S, Tian W, Chen Y, Wang L, Jiang Y, Gao B, Luo D., Free PMC Article | 09/5/2020 |
| TAF7, presumably its TFIID-independent form, binds the promoter and enhances the levels of Pol II at the gene body but not the promoter | TAF7 is a heat-inducible unstable protein and is required for sustained expression of heat shock protein genes.
Nagashimada M, Ueda T, Ishita Y, Sakurai H. | 06/15/2019 |
| EAF1 (239-268) and TAF7 (205-235) peptide interactions were both mapped to the same groove formed by H3 and H4 helices of MED26 N-terminal domain. | Solution Structure of the N-Terminal Domain of Mediator Subunit MED26 and Molecular Characterization of Its Interaction with EAF1 and TAF7.
Lens Z, Cantrelle FX, Peruzzini R, Hanoulle X, Dewitte F, Ferreira E, Baert JL, Monté D, Aumercier M, Villeret V, Verger A, Landrieu I. | 10/14/2017 |
| the MED26-NTD functions as a molecular switch in the exchange of TBP-associated factor 7 (TAF7) for LEC to facilitate the transition from initiation to elongation during transcription of a subset of snRNA genes | MED26 regulates the transcription of snRNA genes through the recruitment of little elongation complex.
Takahashi H, Takigawa I, Watanabe M, Anwar D, Shibata M, Tomomori-Sato C, Sato S, Ranjan A, Seidel CW, Tsukiyama T, Mizushima W, Hayashi M, Ohkawa Y, Conaway JW, Conaway RC, Hatakeyama S., Free PMC Article | 02/13/2016 |
| These results resolve the structural organization of the TAF1-TAF7 module in TFIID and unveil a critical promoter-binding function of TAF1 in transcription regulation. | Crystal structure of a TAF1-TAF7 complex in human transcription factor IID reveals a promoter binding module.
Wang H, Curran EC, Hinds TR, Wang EH, Zheng N., Free PMC Article | 07/25/2015 |
| the surface of the TAF1-TAF7 complex contains two prominent conserved surface pockets, one of which binds selectively to an inhibitory trimethylated histone H3 | Structural and functional insight into TAF1-TAF7, a subcomplex of transcription factor II D.
Bhattacharya S, Lou X, Hwang P, Rajashankar KR, Wang X, Gustafsson JÅ, Fletterick RJ, Jacobson RH, Webb P., Free PMC Article | 08/23/2014 |
| three CTD kinases, CDK7, CDK9, and BRD4, engage in cross-talk, modulating their subsequent C-terminal domain phosphorylation, and also phosphorylate TAF7 | Cross-talk among RNA polymerase II kinases modulates C-terminal domain phosphorylation.
Devaiah BN, Singer DS., Free PMC Article | 02/2/2013 |
| analysis of phosphorylation-dependent regulation of cyclin D1 and cyclin A gene transcription by TFIID subunits TAF1 and TAF7 | Phosphorylation-dependent regulation of cyclin D1 and cyclin A gene transcription by TFIID subunits TAF1 and TAF7.
Kloet SL, Whiting JL, Gafken P, Ranish J, Wang EH., Free PMC Article | 10/20/2012 |
| TAF7, until now considered only a TFIID component and regulator of TAF1-dependent transcription, also regulates TAF1-independent transcription | Novel functions for TAF7, a regulator of TAF1-independent transcription.
Devaiah BN, Lu H, Gegonne A, Sercan Z, Zhang H, Clifford RJ, Lee MP, Singer DS., Free PMC Article | 01/15/2011 |
| TAF7 interacts with the transcription factors, TFIIH and P-TEFb, resulting in the inhibition of their Pol II CTD kinase activities | TFIID component TAF7 functionally interacts with both TFIIH and P-TEFb.
Gegonne A, Weissman JD, Lu H, Zhou M, Dasgupta A, Ribble R, Brady JN, Singer DS., Free PMC Article | 01/21/2010 |
| TAF7 represents a novel c-Jun co-activator mediating activation of AP-1 target genes in response to extracellular signals | TAF7 (TAFII55) plays a role in the transcription activation by c-Jun.
Munz C, Psichari E, Mandilis D, Lavigne AC, Spiliotaki M, Oehler T, Davidson I, Tora L, Angel P, Pintzas A. | 01/21/2010 |
| TAF7 has a role as a basal regulator for mammalian polyamine transport activity and MGBG-induced apoptosis | TATA-binding protein-associated factor 7 regulates polyamine transport activity and polyamine analog-induced apoptosis.
Fukuchi J, Hiipakka RA, Kokontis JM, Nishimura K, Igarashi K, Liao S. | 01/21/2010 |
| These results suggest normal TBP-binding interactions--specifically recognition, stability, and conformation-are disrupted by CldAMP insertion into eukaryotic promoter sequences. | Presence of the anti-leukemic nucleotide analog, 2-chloro-2'-deoxyadenosine-5'-monophosphate, in a promoter sequence alters DNA binding of TATA-binding protein (TBP).
Hartman WR, Walters DE, Hentosh P. | 01/21/2010 |
| Functions as a check-point regulator suppressing premature transcription initiation until preinitiation complex assembly is complete. | TAF7: a possible transcription initiation check-point regulator.
Gegonne A, Weissman JD, Zhou M, Brady JN, Singer DS., Free PMC Article | 01/21/2010 |