Pan-cancer analysis: predictive role of TAP1 in cancer prognosis and response to immunotherapy. | Pan-cancer analysis: predictive role of TAP1 in cancer prognosis and response to immunotherapy. Tu Z, Li K, Ji Q, Huang Y, Lv S, Li J, Wu L, Huang K, Zhu X., Free PMC Article | 02/15/2023 |
TAP1, a potential immune-related prognosis biomarker with functional significance in uveal melanoma. | TAP1, a potential immune-related prognosis biomarker with functional significance in uveal melanoma. Zhu R, Chen YT, Wang BW, You YY, Wang XH, Xie HT, Jiang FG, Zhang MC., Free PMC Article | 02/15/2023 |
Antigen Peptide Transporter 1 (TAP1) Promotes Resistance to MEK Inhibitors in Pancreatic Cancers. | Antigen Peptide Transporter 1 (TAP1) Promotes Resistance to MEK Inhibitors in Pancreatic Cancers. Li B, Feng Y, Hou Q, Fu Y, Luo Y., Free PMC Article | 07/23/2022 |
Association study of TAP and HLA-I gene combination with chronic hepatitis C virus infection in a Han population in China. | Association study of TAP and HLA-I gene combination with chronic hepatitis C virus infection in a Han population in China. Tao Y, Han X, Liu N, Shi L, Shi L, Liu S, Yao Y. | 05/28/2022 |
The association of TAP polymorphisms with non-small-cell lung cancer in the Han Chinese population. | The association of TAP polymorphisms with non-small-cell lung cancer in the Han Chinese population. Liu W, Ma Q, Li C, Li Y, Liu S, Shi L, Yao Y. | 03/19/2022 |
Spotlight on TAP and its vital role in antigen presentation and cross-presentation. | Spotlight on TAP and its vital role in antigen presentation and cross-presentation. Mantel I, Sadiq BA, Blander JM., Free PMC Article | 02/26/2022 |
Transporter associated with antigen processing 1 (TAP1) expression and prognostic analysis in breast, lung, liver, and ovarian cancer. | Transporter associated with antigen processing 1 (TAP1) expression and prognostic analysis in breast, lung, liver, and ovarian cancer. Tabassum A, Samdani MN, Dhali TC, Alam R, Ahammad F, Samad A, Karpiński TM., Free PMC Article | 02/12/2022 |
Association between the TAP1 gene polymorphisms and recurrent respiratory papillomatosis in patients from Western Mexico: A pilot study. | Association between the TAP1 gene polymorphisms and recurrent respiratory papillomatosis in patients from Western Mexico: A pilot study. Palomares-Marin J, Govea-Camacho LH, Araujo-Caballero V, Cazarez-Navarro G, Rodriguez-Preciado SY, Ortiz-Hernandez E, Martinez-Lopez E, Muñoz-Valle JF, Hernandez-Cañaveral II., Free PMC Article | 11/13/2021 |
Association of TAP1 1177A>G and 2090A>G gene polymorphisms with latent tuberculosis infections in sheltered populations, in the metropolitan area of Guadalajara, Mexico: a pilot study. | Association of TAP1 1177A>G and 2090A>G gene polymorphisms with latent tuberculosis infections in sheltered populations, in the metropolitan area of Guadalajara, Mexico: a pilot study. Cazarez-Navarro G, Palomares-Marín J, Rodríguez-Preciado SY, Pereira-Suárez AL, Martínez-López E, Bacilio-Medrano EA, Huerta-Olvera S, Hernández-Cañaveral II., Free PMC Article | 08/28/2021 |
Polymorphisms in transporter associated with antigen presenting are associated with cervical intraepithelial neoplasia and cervical cancer in a Chinese Han population. | Polymorphisms in transporter associated with antigen presenting are associated with cervical intraepithelial neoplasia and cervical cancer in a Chinese Han population. Yang J, Liu W, Yan Z, Li C, Liu S, Yang X, Li Y, Shi L, Yao Y. | 07/24/2021 |
Broadly Antiviral Activities of TAP1 through Activating the TBK1-IRF3-Mediated Type I Interferon Production. | Broadly Antiviral Activities of TAP1 through Activating the TBK1-IRF3-Mediated Type I Interferon Production. Zhao J, Li R, Li Y, Chen J, Feng F, Sun C., Free PMC Article | 05/29/2021 |
Hedgehog signalling mediates drug resistance through targeting TAP1 in hepatocellular carcinoma. | Hedgehog signalling mediates drug resistance through targeting TAP1 in hepatocellular carcinoma. Zhou XT, Ding J, Li HY, Zuo JL, Ge SY, Jia HL, Wu J., Free PMC Article | 05/1/2021 |
Associations of genetic variants at TAP1 and TAP2 with pulmonary tuberculosis risk among the Chinese population. | Associations of genetic variants at TAP1 and TAP2 with pulmonary tuberculosis risk among the Chinese population. Zhang M, Wang X, Zhu Y, Chen S, Chen B, Liu Z., Free PMC Article | 04/24/2021 |
Downregulation of TAP1 in Tumor-Free Tongue Contralateral to Squamous Cell Carcinoma of the Oral Tongue, an Indicator of Better Survival. | Downregulation of TAP1 in Tumor-Free Tongue Contralateral to Squamous Cell Carcinoma of the Oral Tongue, an Indicator of Better Survival. Attaran N, Gu X, Coates PJ, Fåhraeus R, Boldrup L, Wilms T, Wang L, Sgaramella N, Zborayova K, Nylander K., Free PMC Article | 02/27/2021 |
ABCB1 and ABCC2 genetic polymorphism as risk factors for neutropenia in esophageal cancer patients treated with docetaxel, cisplatin, and 5-fluorouracil chemotherapy. | ABCB1 and ABCC2 genetic polymorphism as risk factors for neutropenia in esophageal cancer patients treated with docetaxel, cisplatin, and 5-fluorouracil chemotherapy. Nomura H, Tsuji D, Demachi K, Mochizuki N, Matsuzawa H, Yano T, Daiko H, Fujii S, Kojima T, Itoh K, Kawasaki T. | 02/20/2021 |
Studied transporter 1 ATP binding cassette (TAP1) gene polymorphisms and human menstrual blood papillomavirus DNA as diagnostic/prognostic markers of Cervical Squamous Intraepithelial Lesion. | Menstrual Blood Human Papillomavirus DNA and TAP1 Gene Polymorphisms as Potential Biomarkers for Screening and Monitoring of Cervical Squamous Intraepithelial Lesion. Wong SCC, Au TCC, Chan SCS, Ng LPW, Tsang HF. | 09/21/2019 |
TAP polymorphisms have no or limited effect on peptide transport or MHC class I expression. | The influence of TAP1 and TAP2 gene polymorphisms on TAP function and its inhibition by viral immune evasion proteins. Praest P, Luteijn RD, Brak-Boer IGJ, Lanfermeijer J, Hoelen H, Ijgosse L, Costa AI, Gorham RD Jr, Lebbink RJ, Wiertz EJHJ. | 03/30/2019 |
Our finding suggested that TAP1-rs1135216, TAP1-rs4148873, TAP2-rs2228396, TAP2-rs241447 and TAP2-rs4148873 might not be involved in cancer risk, but the T allele of TAP2-rs4148876 might be a potential biomarker for judging cancer risk [review, meta-analysis] | An update meta-analysis and systematic review of TAP polymorphisms as potential biomarkers for judging cancer risk. Meng J, Li W, Zhang M, Hao Z, Fan S, Zhang L, Liang C. | 11/10/2018 |
In a meta-analyses of 6 studies with 415 cases and 659 controls, a significant association was found between TAP1-333Val, TAP1-637Gly, and TAP2-565Thr and ankylosing spondylitis compared with combined control group. | Genetic association between TAP1 and TAP2 polymorphisms and ankylosing spondylitis: a systematic review and meta-analysis. Qian Y, Wang G, Xue F, Chen L, Wang Y, Tang L, Yang H. | 04/21/2018 |
Both TAP1 and TAP2 overexpression in breast cancer might be an indicator of an aggressive breast tumor | Downregulation of TAP1 and TAP2 in early stage breast cancer. Henle AM, Nassar A, Puglisi-Knutson D, Youssef B, Knutson KL., Free PMC Article | 12/9/2017 |
The structure shows that herpes simplex virus ICP47 traps human TAP in an inactive conformation distinct from the normal transport cycle. | Structure of the transporter associated with antigen processing trapped by herpes simplex virus. Oldham ML, Grigorieff N, Chen J., Free PMC Article | 11/4/2017 |
PSMB8 rs2071464 was associated with generalized and active vitiligo from Gujarat whereas TAP1 rs1135216 showed no association. The down-regulation of PSMB8 in patients with risk genotype 'CC' advocates the vital role of PSMB8 in the autoimmune basis of vitiligo. | A case-control study on association of proteasome subunit beta 8 (PSMB8) and transporter associated with antigen processing 1 (TAP1) polymorphisms and their transcript levels in vitiligo from Gujarat. Jadeja SD, Mansuri MS, Singh M, Dwivedi M, Laddha NC, Begum R., Free PMC Article | 09/30/2017 |
Study compared the biochemical properties of the nucleotide-binding domains (NBD) of human and rat TAP1; suggests that although the D-helix sequence is not conserved in ABC transporters, its precise positioning within the NBD structure has a critical role in NBD dimerization. | D-helix influences dimerization of the ATP-binding cassette (ABC) transporter associated with antigen processing 1 (TAP1) nucleotide-binding domain. Vakkasoglu AS, Srikant S, Gaudet R., Free PMC Article | 09/23/2017 |
Significant associations between sorafenib exposure and the studied polymorphisms were observed for ABCB2 | Correlation between clinical response to sorafenib in hepatocellular carcinoma treatment and polymorphisms of P-glycoprotein (ABCB1) and of breast cancer resistance protein (ABCG2): monocentric study. Tandia M, Mhiri A, Paule B, Saffroy R, Cailliez V, Noé G, Farinotti R, Bonhomme-Faivre L. | 06/24/2017 |
this study shows that TAP1 plays a novel role in the negative regulation of virus-triggered NF-kappaB signaling and the innate immune response by targeting the TAK1 complex | Inducible TAP1 Negatively Regulates the Antiviral Innate Immune Response by Targeting the TAK1 Complex. Xia Z, Xu G, Yang X, Peng N, Zuo Q, Zhu S, Hao H, Liu S, Zhu Y. | 05/6/2017 |