| A New Case Series Suggests That SCA48 (ATX/STUB1) Is Primarily a Monogenic Disorder. | A New Case Series Suggests That SCA48 (ATX/STUB1) Is Primarily a Monogenic Disorder.
van Prooije TH, Pennings M, Dorresteijn L, Gardeitchik T, Odekerken VJJ, Oosterloo M, Pedersen A, Verschuuren-Bemelmans CC, Vrancken A, Kamsteeg EJ, van de Warrenburg BPC. | 11/1/2024 |
| The New Face of Dynamic Mutation-The CAA [CAG]n CAA CAG Motif as a Mutable Unit in the TBP Gene Causative for Spino-Cerebellar Ataxia Type 17. | The New Face of Dynamic Mutation-The CAA [CAG]n CAA CAG Motif as a Mutable Unit in the TBP Gene Causative for Spino-Cerebellar Ataxia Type 17.
Hoffman-Zacharska D, Sulek A., Free PMC Article | 08/14/2024 |
| Taf1 N-terminal domain 2 (TAND2) of TFIID promotes formation of stable and mobile unstable TBP-TATA complexes. | Taf1 N-terminal domain 2 (TAND2) of TFIID promotes formation of stable and mobile unstable TBP-TATA complexes.
Miyasaka S, Kitada R, Kokubo T. | 10/10/2023 |
| Hierarchical TAF1-dependent co-translational assembly of the basal transcription factor TFIID. | Hierarchical TAF1-dependent co-translational assembly of the basal transcription factor TFIID.
Bernardini A, Mukherjee P, Scheer E, Kamenova I, Antonova S, Mendoza Sanchez PK, Yayli G, Morlet B, Timmers HTM, Tora L., Free PMC Article | 08/25/2023 |
| TATA-box-binding protein promotes hepatocellular carcinoma metastasis through epithelial-mesenchymal transition. | TATA-box-binding protein promotes hepatocellular carcinoma metastasis through epithelial-mesenchymal transition.
Cao J, Yang S, Luo T, Yang R, Zhu H, Zhao T, Jiang K, Xu B, Wang Y, Chen F., Free PMC Article | 06/22/2023 |
| Complex Ataxia-Dementia Phenotype in Patients with Digenic TBP/STUB1 Spinocerebellar Ataxia. | Complex Ataxia-Dementia Phenotype in Patients with Digenic TBP/STUB1 Spinocerebellar Ataxia.
Nanetti L, Magri S, Fichera M, Castaldo A, Nigri A, Pinardi C, Mongelli A, Sarro L, Pareyson D, Grisoli M, Gellera C, Di Bella D, Mariotti C, Taroni F. | 04/21/2023 |
| Genotype-Phenotype Correlations for ATX-TBP (SCA17): MDSGene Systematic Review. | Genotype-Phenotype Correlations for ATX-TBP (SCA17): MDSGene Systematic Review.
Rossi M, Hamed M, Rodríguez-Antigüedad J, Cornejo-Olivas M, Breza M, Lohmann K, Klein C, Rajalingam R, Marras C, van de Warrenburg BP. | 03/24/2023 |
| Intermediate repeat expansions of TBP and STUB1: Genetic modifier or pure digenic inheritance in spinocerebellar ataxias? | Intermediate repeat expansions of TBP and STUB1: Genetic modifier or pure digenic inheritance in spinocerebellar ataxias?
Barbier M, Davoine CS, Petit E, Porché M, Guillot-Noel L, Sayah S, Fauret AL, Neau JP, Guyant-Maréchal L, Deffond D, Tranchant C, Goizet C, Coarelli G, Castrioto A, Klebe S, Ewenczyk C, Heinzmann A, Charles P, Tchikviladzé M, Van Broeckhoven C, Brice A, Durr A. | 02/28/2023 |
| Differential dependencies of human RNA polymerase II promoters on TBP, TAF1, TFIIB and XPB. | Differential dependencies of human RNA polymerase II promoters on TBP, TAF1, TFIIB and XPB.
Santana JF, Collins GS, Parida M, Luse DS, Price DH., Free PMC Article | 11/19/2022 |
| Mutation analysis of the TATA box-binding protein (TBP) gene in Russian patients with spinocerebellar ataxia and Huntington disease-like phenotype. | Mutation analysis of the TATA box-binding protein (TBP) gene in Russian patients with spinocerebellar ataxia and Huntington disease-like phenotype.
Ivanova E, Nuzhnyi E, Abramycheva N, Klyushnikov S, Fedotova E, Illarioshkin S. | 10/29/2022 |
| TBP, PPIA, YWHAZ and EF1A1 Are the Most Stably Expressed Genes during Osteogenic Differentiation. | TBP, PPIA, YWHAZ and EF1A1 Are the Most Stably Expressed Genes during Osteogenic Differentiation.
Franko N, Vrščaj LA, Zore T, Ostanek B, Marc J, Lojk J., Free PMC Article | 04/30/2022 |
| Digenic inheritance of STUB1 variants and TBP polyglutamine expansions explains the incomplete penetrance of SCA17 and SCA48. | Digenic inheritance of STUB1 variants and TBP polyglutamine expansions explains the incomplete penetrance of SCA17 and SCA48.
Magri S, Nanetti L, Gellera C, Sarto E, Rizzo E, Mongelli A, Ricci B, Fancellu R, Sambati L, Cortelli P, Brusco A, Bruzzone MG, Mariotti C, Di Bella D, Taroni F. | 03/26/2022 |
| Small-expanded allele spinocerebellar ataxia 17: imaging and phenotypic variability. | Small-expanded allele spinocerebellar ataxia 17: imaging and phenotypic variability.
Paolini Paoletti F, Prontera P, Nigro P, Simoni S, Cappelletti G, Filidei M, Calabresi P, Parnetti L, Tambasco N. | 09/25/2021 |
| Investigating TBP CAG/CAA trinucleotide repeat expansions in a Taiwanese cohort with ALS. | Investigating TBP CAG/CAA trinucleotide repeat expansions in a Taiwanese cohort with ALS.
Jih KY, Lin KP, Tsai PC, Soong BW, Liao YC, Lee YC. | 08/28/2021 |
| Architecture of the multi-functional SAGA complex and the molecular mechanism of holding TBP. | Architecture of the multi-functional SAGA complex and the molecular mechanism of holding TBP.
Ben-Shem A, Papai G, Schultz P. | 07/24/2021 |
| Molecular determinants underlying functional innovations of TBP and their impact on transcription initiation. | Molecular determinants underlying functional innovations of TBP and their impact on transcription initiation.
Ravarani CNJ, Flock T, Chavali S, Anandapadamanaban M, Babu MM, Balaji S., Free PMC Article | 08/15/2020 |
| TATA-box binding protein O-GlcNAcylation at T114 regulates formation of BTAF1-TFIID complex and is critical for the genetic regulation of energy metabolism. | TATA-Box Binding Protein O-GlcNAcylation at T114 Regulates Formation of the B-TFIID Complex and Is Critical for Metabolic Gene Regulation.
Hardivillé S, Banerjee PS, Selen Alpergin ES, Smith DM, Han G, Ma J, Talbot CC Jr, Hu P, Wolfgang MJ, Hart GW., Free PMC Article | 07/11/2020 |
| a direct role for poly-Ser domain-dependent TFIID interaction in recruiting super-elongation complex components on target DNA, is reported. | Multivalent Role of Human TFIID in Recruiting Elongation Components at the Promoter-Proximal Region for Transcriptional Control.
Yadav D, Ghosh K, Basu S, Roeder RG, Biswas D., Free PMC Article | 03/14/2020 |
| A 2.4 -A resolution crystal structure reveals that human MYC amino acids 98-111 interact with TBP in the presence of the amino-terminal domain 1 of TBP-associated factor 1 (TAF1(TAND1)). | Multiple direct interactions of TBP with the MYC oncoprotein.
Wei Y, Resetca D, Li Z, Johansson-Åkhe I, Ahlner A, Helander S, Wallenhammar A, Morad V, Raught B, Wallner B, Kokubo T, Tong Y, Penn LZ, Sunnerhagen M. | 02/22/2020 |
| Study findings demonstrate TBP as mechanism of host-response activation by HIV-1 Tat and suggest that promoter plasticity is a challenge imposed by co-morbid factors such as stimulant drug addiction. | Modeling the Function of TATA Box Binding Protein in Transcriptional Changes Induced by HIV-1 Tat in Innate Immune Cells and the Effect of Methamphetamine Exposure.
Tjitro R, Campbell LA, Basova L, Johnson J, Najera JA, Lindsey A, Marcondes MCG., Free PMC Article | 10/26/2019 |
| these findings provide a mechanistic model for the specific loading of TBP by TFIID onto the promoter. | Structure of human TFIID and mechanism of TBP loading onto promoter DNA.
Patel AB, Louder RK, Greber BJ, Grünberg S, Luo J, Fang J, Liu Y, Ranish J, Hahn S, Nogales E., Free PMC Article | 02/16/2019 |
| In an integrative approach combining crystal coordinates, biochemical analyses and data from cross-linking mass-spectrometry (CLMS), the authors determine the architecture of the TAF11/TAF13/TBP complex, revealing TAF11/TAF13 interaction with the DNA binding surface of TBP. | Architecture of TAF11/TAF13/TBP complex suggests novel regulation properties of general transcription factor TFIID.
Gupta K, Watson AA, Baptista T, Scheer E, Chambers AL, Koehler C, Zou J, Obong-Ebong I, Kandiah E, Temblador A, Round A, Forest E, Man P, Bieniossek C, Laue ED, Lemke EA, Rappsilber J, Robinson CV, Devys D, Tora L, Berger I., Free PMC Article | 06/30/2018 |
| these studies support the idea that increases in TBP expression contribute to enhanced VEGFA transcription early in colorectal cancer development to drive tumorigenesis. | Elevated TATA-binding protein expression drives vascular endothelial growth factor expression in colon cancer.
Johnson SAS, Lin JJ, Walkey CJ, Leathers MP, Coarfa C, Johnson DL., Free PMC Article | 04/28/2018 |
| The genetic animal models of SCA17 clearly indicate that the phenotypes are dependent on the expression levels of mutant TBP and the length of CAG/glutamine repeat. | Genetically modified rodent models of SCA17.
Cui Y, Yang S, Li XJ, Li S., Free PMC Article | 04/21/2018 |
| we observed that carriers of either ATXN7 or TBP alleles with relatively large CAG repeat sizes in both alleles had a substantially increased risk of lifetime depression. | Large normal-range TBP and ATXN7 CAG repeat lengths are associated with increased lifetime risk of depression.
Gardiner SL, van Belzen MJ, Boogaard MW, van Roon-Mom WMC, Rozing MP, van Hemert AM, Smit JH, Beekman ATF, van Grootheest G, Schoevers RA, Oude Voshaar RC, Comijs HC, Penninx BWJH, van der Mast RC, Roos RAC, Aziz NA., Free PMC Article | 04/7/2018 |