| Overexpression of transcription factor TBX5 inhibits the activation of YAP1-TEAD1 pathway to promote ferroptosis in lung cancer cells. | Overexpression of transcription factor TBX5 inhibits the activation of YAP1-TEAD1 pathway to promote ferroptosis in lung cancer cells.
Ma R, Hu K, Dai S, Wang Y. | 06/5/2024 |
| TBX5 genetic variants and SCD-CAD susceptibility: insights from Chinese Han cohorts. | TBX5 genetic variants and SCD-CAD susceptibility: insights from Chinese Han cohorts.
Rui Y, Zhou J, Zhen X, Zhang J, Liu S, Gao Y., Free PMC Article | 03/27/2024 |
| TBX5 variants and cardiac phenotype: A systematic review of the literature and a novel variant. | TBX5 variants and cardiac phenotype: A systematic review of the literature and a novel variant.
Møller Nielsen AK, Dehn AM, Hjortdal V, Larsen LA. | 03/20/2024 |
| Prioritizing cardiovascular disease-associated variants altering NKX2-5 and TBX5 binding through an integrative computational approach. | Prioritizing cardiovascular disease-associated variants altering NKX2-5 and TBX5 binding through an integrative computational approach.
Peña-Martínez EG, Pomales-Matos DA, Rivera-Madera A, Messon-Bird JL, Medina-Feliciano JG, Sanabria-Alberto L, Barreiro-Rosario AC, Rivera-Del Valle J, Rodríguez-Ríos JM, Rodríguez-Martínez JA., Free PMC Article | 01/3/2024 |
| CircTBX5 knockdown modulates the miR-558/MyD88 axis to alleviate IL-1beta-induced inflammation, apoptosis and extracellular matrix degradation in chondrocytes via inactivating the NF-kappaB signaling. | CircTBX5 knockdown modulates the miR-558/MyD88 axis to alleviate IL-1β-induced inflammation, apoptosis and extracellular matrix degradation in chondrocytes via inactivating the NF-κB signaling.
Wei W, Mu H, Cui Q, Yu P, Liu T, Wang T, Sheng L., Free PMC Article | 07/3/2023 |
| hsa_circ_0038382 upregulates T-box transcription factor 5 to inhibit keloid formation by interacting with miR-940. | hsa_circ_0038382 upregulates T-box transcription factor 5 to inhibit keloid formation by interacting with miR-940.
Cai M, Hu Z, Liu L, Su J. | 05/30/2023 |
| Diverse ancestry whole-genome sequencing association study identifies TBX5 and PTK7 as susceptibility genes for posterior urethral valves. | Diverse ancestry whole-genome sequencing association study identifies TBX5 and PTK7 as susceptibility genes for posterior urethral valves.
Chan MMY, Sadeghi-Alavijeh O, Lopes FM, Hilger AC, Stanescu HC, Voinescu CD, Beaman GM, Newman WG, Zaniew M, Weber S, Ho YM, Connolly JO, Wood D, Maj C, Stuckey A, Kousathanas A, Genomics England Research Consortium, Kleta R, Woolf AS, Bockenhauer D, Levine AP, Gale DP., Free PMC Article | 10/8/2022 |
| TBX5 variant with the novel phenotype of mixedtype total anomalous pulmonary venous return in HoltOram Syndrome and variable intrafamilial heart defects. | TBX5 variant with the novel phenotype of mixed‑type total anomalous pulmonary venous return in Holt‑Oram Syndrome and variable intrafamilial heart defects.
Azab B, Aburizeg D, Ji W, Jeffries L, Isbeih NJ, Al-Akily AS, Mohammad H, Osba YA, Shahin MA, Dardas Z, Hatmal MM, Al-Ammouri I, Lakhani S., Free PMC Article | 05/14/2022 |
| Identification of a novel TBX5 c.755 + 1 G > A variant and related pathogenesis in a family with Holt-Oram syndrome. | Identification of a novel TBX5 c.755 + 1 G > A variant and related pathogenesis in a family with Holt-Oram syndrome.
Wang DG, Dong XS, Xiong Y, Li ZM, Xie YJ, Liang SH, Huang TH., Free PMC Article | 04/23/2022 |
| Patient-Specific TBX5-G125R Variant Induces Profound Transcriptional Deregulation and Atrial Dysfunction. | Patient-Specific TBX5-G125R Variant Induces Profound Transcriptional Deregulation and Atrial Dysfunction.
van Ouwerkerk AF, Bosada FM, van Duijvenboden K, Houweling AC, Scholman KT, Wakker V, Allaart CP, Uhm JS, Mathijssen IB, Baartscheer T, Postma AV, Barnett P, Verkerk AO, Boukens BJ, Christoffels VM., Free PMC Article | 03/12/2022 |
| MicroRNA-603 Promotes Progression of Cutaneous Melanoma by Regulating TBX5. | MicroRNA-603 Promotes Progression of Cutaneous Melanoma by Regulating TBX5.
Dong X, Wang Y, Qu Y, Liu J, Feng X, Xu X., Free PMC Article | 03/5/2022 |
| TBX5-AS1, an enhancer RNA, is a potential novel prognostic biomarker for lung adenocarcinoma. | TBX5-AS1, an enhancer RNA, is a potential novel prognostic biomarker for lung adenocarcinoma.
Cheng L, Han T, Chen B, Nie K, Peng W., Free PMC Article | 11/6/2021 |
| Modeling Human TBX5 Haploinsufficiency Predicts Regulatory Networks for Congenital Heart Disease. | Modeling Human TBX5 Haploinsufficiency Predicts Regulatory Networks for Congenital Heart Disease.
Kathiriya IS, Rao KS, Iacono G, Devine WP, Blair AP, Hota SK, Lai MH, Garay BI, Thomas R, Gong HZ, Wasson LK, Goyal P, Sukonnik T, Hu KM, Akgun GA, Bernard LD, Akerberg BN, Gu F, Li K, Speir ML, Haeussler M, Pu WT, Stuart JM, Seidman CE, Seidman JG, Heyn H, Bruneau BG., Free PMC Article | 08/28/2021 |
| Tbx5 inhibits hedgehog signaling in determination of digit identity. | Tbx5 inhibits hedgehog signaling in determination of digit identity.
Xu H, Xiang M, Qin Y, Cheng H, Chen D, Fu Q, Zhang KK, Xie L., Free PMC Article | 08/14/2021 |
| TBX3 and TBX5 duplication: A family with an atypical overlapping Holt-Oram/ulnar-mammary syndrome phenotype. | TBX3 and TBX5 duplication: A family with an atypical overlapping Holt-Oram/ulnar-mammary syndrome phenotype.
Cenni C, Andres S, Hempel M, Strom TM, Thomas E, Davies A, Timoney N, Frigiola A, Logan M, Holder-Espinasse M. | 08/14/2021 |
| [A Literature Review on the Role of TBX5 in Expression and Progression of Lung Cancer: Current Perspectives]. | [A Literature Review on the Role of TBX5 in Expression and Progression of Lung Cancer: Current Perspectives].
Huang W, Li P, Qiu X., Free PMC Article | 07/31/2021 |
| TBX5-encoded T-box transcription factor 5 variant T223M is associated with long QT syndrome and pediatric sudden cardiac death. | TBX5-encoded T-box transcription factor 5 variant T223M is associated with long QT syndrome and pediatric sudden cardiac death.
Markunas AM, Manivannan PKR, Ezekian JE, Agarwal A, Eisner W, Alsina K, Allen HD, Wray GA, Kim JJ, Wehrens XHT, Landstrom AP., Free PMC Article | 07/24/2021 |
| Functional analysis of two novel TBX5 variants present in individuals with Holt-Oram syndrome with different clinical manifestations. | Functional analysis of two novel TBX5 variants present in individuals with Holt-Oram syndrome with different clinical manifestations.
Varela D, Varela T, Conceição N, Ferreira Â, Marques N, Silva AP, Azevedo P, Pereira S, Camacho A, de Jesus I, Cancela ML. | 06/26/2021 |
| Familial dilated cardiomyopathy associated with pathogenic TBX5 variants: Expanding the cardiac phenotype associated with Holt-Oram syndrome. | Familial dilated cardiomyopathy associated with pathogenic TBX5 variants: Expanding the cardiac phenotype associated with Holt-Oram syndrome.
Patterson J, Coats C, McGowan R. | 05/1/2021 |
| Hypermethylation-mediated down-regulation of lncRNA TBX5-AS1:2 in Tetralogy of Fallot inhibits cell proliferation by reducing TBX5 expression. | Hypermethylation-mediated down-regulation of lncRNA TBX5-AS1:2 in Tetralogy of Fallot inhibits cell proliferation by reducing TBX5 expression.
Ma J, Chen S, Hao L, Sheng W, Chen W, Ma X, Zhang B, Ma D, Huang G., Free PMC Article | 05/1/2021 |
| Transcriptional regulation of human T-box 5 gene (TBX5) by bone- and cardiac-related transcription factors. | Transcriptional regulation of human T-box 5 gene (TBX5) by bone- and cardiac-related transcription factors.
Varela D, Conceição N, Cancela ML. | 01/23/2021 |
| HDAC4 and 5 repression of TBX5 is relieved by protein kinase D1. | HDAC4 and 5 repression of TBX5 is relieved by protein kinase D1.
Ghosh TK, Aparicio-Sánchez JJ, Buxton S, Brook JD., Free PMC Article | 11/21/2020 |
| The role of ESCO2, SALL4 and TBX5 genes in the susceptibility to thalidomide teratogenesis. | The role of ESCO2, SALL4 and TBX5 genes in the susceptibility to thalidomide teratogenesis.
Gomes JDA, Kowalski TW, Fraga LR, Macedo GS, Sanseverino MTV, Schuler-Faccini L, Vianna FSL., Free PMC Article | 10/31/2020 |
| A New TBX5 Loss-of-Function Mutation Contributes to Congenital Heart Defect and Atrioventricular Block. | A New TBX5 Loss-of-Function Mutation Contributes to Congenital Heart Defect and Atrioventricular Block.
Zhang Y, Sun YM, Xu YJ, Zhao CM, Yuan F, Guo XJ, Guo YH, Yang CX, Gu JN, Qiao Q, Wang J, Yang YQ. | 08/15/2020 |
| Our results show that the S156N and P163S variants may affect the transcriptional function of KLF13 and physical interaction with TBX5. These results identified KLF13 as a potential genetic risk factor for congenital heart disease. | Identification and analysis of KLF13 variants in patients with congenital heart disease.
Li W, Li B, Li T, Zhang E, Wang Q, Chen S, Sun K., Free PMC Article | 07/18/2020 |