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    TCF3 transcription factor 3 [ Homo sapiens (human) ]

    Gene ID: 6929, updated on 17-Jun-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Transcription factor 3 is dysregulated in megakaryocytes in myelofibrosis.

    Transcription factor 3 is dysregulated in megakaryocytes in myelofibrosis.
    Collinson RJ, Wilson L, Boey D, Ng ZY, Mirzai B, Chuah HS, Howman R, Grove CS, Malherbe JAJ, Leahy MF, Linden MD, Fuller KA, Erber WN, Guo BB.

    02/6/2024
    Rare TCF3 variants associated with pediatric B cell acute lymphoblastic leukemia.

    Rare TCF3 variants associated with pediatric B cell acute lymphoblastic leukemia.
    Miyamoto S, Urayama KY, Arakawa Y, Koh K, Yuza Y, Hasegawa D, Taneyama Y, Noguchi Y, Yanagimachi M, Inukai T, Ota S, Takahashi H, Keino D, Toyama D, Takita J, Tomizawa D, Morio T, Koike K, Moriwaki K, Sato Y, Fujimura J, Morita D, Sekinaka Y, Nakamura K, Sakashita K, Goto H, Manabe A, Takagi M.

    02/2/2024
    Transcription Factor TCF3 Promotes Macrophage-Mediated Inflammation and MMP Secretion in Abdominal Aortic Aneurysm by Regulating miR-143-5p /CCL20.

    Transcription Factor TCF3 Promotes Macrophage-Mediated Inflammation and MMP Secretion in Abdominal Aortic Aneurysm by Regulating miR-143-5p /CCL20.
    Li Y, Li R, Li Y, Li G, Zhao Y, Mou H, Chen Y, Xiao L, Gong K., Free PMC Article

    12/15/2023
    E47 as a novel glucocorticoid-dependent gene mediating lipid metabolism in patients with endogenous glucocorticoid excess.

    E47 as a novel glucocorticoid-dependent gene mediating lipid metabolism in patients with endogenous glucocorticoid excess.
    Zhang W, Nowotny H, Theodoropoulou M, Simon J, Hemmer CM, Bidlingmaier M, Auer MK, Reincke M, Uhlenhaut H, Reisch N., Free PMC Article

    12/6/2023
    TCF3 haploinsufficiency defined by immune, clinical, gene-dosage, and murine studies.

    TCF3 haploinsufficiency defined by immune, clinical, gene-dosage, and murine studies.
    Boast B, Goel S, González-Granado LI, Niemela J, Stoddard J, Edwards ESJ, Seneviratne S, Spensberger D, Quesada-Espinosa JF, Allende LM, McDonnell J, Haseley A, Lesmana H, Walkiewicz MA, Muhammad E, Bosco JJ, Fleisher TA, Cohen S, Holland SM, van Zelm MC, Enders A, Kuehn HS, Rosenzweig SD.,

    11/1/2023
    Molecular characterization of TCF3::PBX1 chromosomal breakpoints in acute lymphoblastic leukemia and their use for measurable residual disease assessment.

    Molecular characterization of TCF3::PBX1 chromosomal breakpoints in acute lymphoblastic leukemia and their use for measurable residual disease assessment.
    Burmeister T, Gröger D, Gökbuget N, Spriewald B, Starck M, Elmaagacli A, Hoelzer D, Keller U, Schwartz S., Free PMC Article

    09/19/2023
    Transcription factor 3 promotes migration and invasion potential and maintains cancer stemness by activating ID1 expression in esophageal squamous cell carcinoma.

    Transcription factor 3 promotes migration and invasion potential and maintains cancer stemness by activating ID1 expression in esophageal squamous cell carcinoma.
    Li ZX, Sun MC, Fang K, Zhao ZY, Leng ZY, Zhang ZH, Xu AP, Chu Y, Zhang L, Lian J, Chen T, Xu MD., Free PMC Article

    08/30/2023
    Exportin XPO7 acts as an oncogenic factor in prostate cancer via upregulation of TCF3.

    Exportin XPO7 acts as an oncogenic factor in prostate cancer via upregulation of TCF3.
    Lin Y, Zhan M, Xu B.

    08/1/2023
    Identification of TCF3 germline variants in pediatric B-cell acute lymphoblastic leukemia.

    Identification of TCF3 germline variants in pediatric B-cell acute lymphoblastic leukemia.
    Escherich C, Chen W, Miyamoto S, Namikawa Y, Yang W, Teachey DT, Li Z, Raetz EA, Larsen E, Devidas M, Martin PL, Bowman WP, Wu G, Pui CH, Hunger SP, Loh ML, Takagi M, Yang JJ., Free PMC Article

    05/18/2023
    FBXL2 promotes E47 protein instability to inhibit breast cancer stemness and paclitaxel resistance.

    FBXL2 promotes E47 protein instability to inhibit breast cancer stemness and paclitaxel resistance.
    Li F, Niu M, Qin K, Guo R, Yi Y, Xu J, Li L, Xie S, Fu M, Wen N, Liao W, Xiao ZJ.

    02/4/2023
    [Expression of TCF3 in Burkitt's Lymphoma and Its Proliferative Effect and Prognostic Significance].

    [Expression of TCF3 in Burkitt's Lymphoma and Its Proliferative Effect and Prognostic Significance].
    Dong LH, Huang JJ, Liu J, Gao X, DU JW, Li YF.

    10/15/2022
    TCF3 protein was highly expressed in pediatric Burkitt lymphoma and predicts poor prognosis: a single-center study.

    TCF3 protein was highly expressed in pediatric Burkitt lymphoma and predicts poor prognosis: a single-center study.
    Man J, Wang H, Qian X, Chen L, Ma Y, Qian M, Zhai X.

    10/15/2022
    Genetic features of B-cell lymphoblastic lymphoma with TCF3-PBX1.

    Genetic features of B-cell lymphoblastic lymphoma with TCF3-PBX1.
    Shirai R, Osumi T, Sato-Otsubo A, Nakabayashi K, Mori T, Yoshida M, Yoshida K, Kohri M, Ishihara T, Yasue S, Imamura T, Endo M, Miyamoto S, Ohki K, Sanada M, Kiyokawa N, Ogawa S, Yoshioka T, Hata K, Takagi M, Kato M., Free PMC Article

    09/24/2022
    Overexpression of transcription factor 3 drives hepatocarcinoma development by enhancing cell proliferation via activating Wnt signaling pathway.

    Overexpression of transcription factor 3 drives hepatocarcinoma development by enhancing cell proliferation via activating Wnt signaling pathway.
    Pu XY, Zheng DF, Lv T, Zhou YJ, Yang JY, Jiang L.

    08/6/2022
    ID proteins promote the survival and primed-to-naive transition of human embryonic stem cells through TCF3-mediated transcription.

    ID proteins promote the survival and primed-to-naive transition of human embryonic stem cells through TCF3-mediated transcription.
    Jiang H, Du M, Li Y, Zhou T, Lei J, Liang H, Zhong Z, Al-Lamki RS, Jiang M, Yang J., Free PMC Article

    07/2/2022
    Transcriptional factor 3 binds to sirtuin 1 to activate the Wnt/beta-catenin signaling in cervical cancer.

    Transcriptional factor 3 binds to sirtuin 1 to activate the Wnt/β-catenin signaling in cervical cancer.
    Yu X, Li Z, Bai R, Tang F., Free PMC Article

    05/28/2022
    TCF3 Induces DNMT1 Expression to Regulate Wnt Signaling Pathway in Glioma.

    TCF3 Induces DNMT1 Expression to Regulate Wnt Signaling Pathway in Glioma.
    Zeng W, Jiang H, Wang Y, Wang C, Yu B.

    05/21/2022
    TCF3 regulates human endometrial stromal cell proliferation and migration in RPL.

    TCF3 regulates human endometrial stromal cell proliferation and migration in RPL.
    Wei XW, Liu XQ, Zhang YC, Qin CM, Lin Y, Tian FJ.

    04/9/2022
    SHMT2 inhibition disrupts the TCF3 transcriptional survival program in Burkitt lymphoma.

    SHMT2 inhibition disrupts the TCF3 transcriptional survival program in Burkitt lymphoma.
    Wilke AC, Doebele C, Zindel A, Lee KS, Rieke SA, Ceribelli M, Comoglio F, Phelan JD, Wang JQ, Pikman Y, Jahn D, Häupl B, Schneider C, Scheich S, Tosto FA, Bohnenberger H, Stauder P, Schnütgen F, Slabicki M, Coulibaly ZA, Wolf S, Bojarczuk K, Chapuy B, Brandts CH, Stroebel P, Lewis CA, Engelke M, Xu X, Kim H, Dang TH, Schmitz R, Hodson DJ, Stegmaier K, Urlaub H, Serve H, Schmitt CA, Kreuz F, Knittel G, Rabinowitz JD, Reinhardt HC, Vander Heiden MG, Thomas C, Staudt LM, Zenz T, Oellerich T., Free PMC Article

    03/12/2022
    Genome-Wide Association Study of Susceptibility Loci for TCF3-PBX1 Acute Lymphoblastic Leukemia in Children.

    Genome-Wide Association Study of Susceptibility Loci for TCF3-PBX1 Acute Lymphoblastic Leukemia in Children.
    Lee SHR, Qian M, Yang W, Diedrich JD, Raetz E, Yang W, Dong Q, Devidas M, Pei D, Yeoh A, Cheng C, Pui CH, Evans WE, Mullighan CG, Hunger SP, Savic D, Relling MV, Loh ML, Yang JJ., Free PMC Article

    02/26/2022
    Transcription factor 3 (TCF3) combined with histone deacetylase 3 (HDAC3) down-regulates microRNA-101 to promote Burkitt lymphoma cell proliferation and inhibit apoptosis.

    Transcription factor 3 (TCF3) combined with histone deacetylase 3 (HDAC3) down-regulates microRNA-101 to promote Burkitt lymphoma cell proliferation and inhibit apoptosis.
    Dong L, Huang J, Zu P, Liu J, Gao X, Du J, Li Y., Free PMC Article

    02/19/2022
    Mechanistic basis for chromosomal translocations at the E2A gene and its broader relevance to human B cell malignancies.

    Mechanistic basis for chromosomal translocations at the E2A gene and its broader relevance to human B cell malignancies.
    Liu D, Loh YE, Hsieh CL, Lieber MR., Free PMC Article

    02/12/2022
    TCF3 Dominant Negative Variant Causes an Early Block in B-Lymphopoiesis and Agammaglobulinemia.

    TCF3 Dominant Negative Variant Causes an Early Block in B-Lymphopoiesis and Agammaglobulinemia.
    Al Sheikh E, Arkwright PD, Herwadkar A, Hussell T, Briggs TA.

    02/5/2022
    E2A ablation enhances proportion of nodal-like cardiomyocytes in cardiac-specific differentiation of human embryonic stem cells.

    E2A ablation enhances proportion of nodal-like cardiomyocytes in cardiac-specific differentiation of human embryonic stem cells.
    Li X, Gao F, Wang X, Liang Q, Bai A, Liu Z, Chen X, Li E, Chen S, Lu C, Qian R, Sun N, Liang P, Xu C., Free PMC Article

    01/29/2022
    E2A Modulates Stemness, Metastasis, and Therapeutic Resistance of Breast Cancer.

    E2A Modulates Stemness, Metastasis, and Therapeutic Resistance of Breast Cancer.
    López-Menéndez C, Vázquez-Naharro A, Santos V, Dubus P, Santamaría PG, Martínez-Ramírez Á, Portillo F, Moreno-Bueno G, Faraldo MM, Cano A., Free PMC Article

    01/8/2022
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