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    MIR551B microRNA 551b [ Homo sapiens (human) ]

    Gene ID: 693136, updated on 17-Jun-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    miR-148a and miR-551b-5p regulate inflammatory responses via regulating autophagy in acute pancreatitis.

    miR-148a and miR-551b-5p regulate inflammatory responses via regulating autophagy in acute pancreatitis.
    Wei H, Zhao H, Cheng D, Zhu Z, Xia Z, Lu D, Yu J, Dong R, Yue J.

    01/29/2024
    METTL9 derived circular RNA circ-METTL9 sponges miR-551b-5p to accelerate colorectal cancer progression by upregulating CDK6.

    METTL9 derived circular RNA circ-METTL9 sponges miR-551b-5p to accelerate colorectal cancer progression by upregulating CDK6.
    Li M, Zhi Z, Jiang X, Duan GC, Zhu WN, Pang Z, Wang L, Ge R, Dai X, Liu JM, Chen TY, Jia JJ, Li JM, Sun LN.

    08/22/2023
    Exosomal microRNA-551b-3p from bone marrow-derived mesenchymal stromal cells inhibits breast cancer progression via regulating TRIM31/Akt signaling.

    Exosomal microRNA-551b-3p from bone marrow-derived mesenchymal stromal cells inhibits breast cancer progression via regulating TRIM31/Akt signaling.
    Yang Z, Xu B, Wu S, Yang W, Luo R, Geng S, Xin Z, Jin W, Shen X, Gu X, Zhang H, Wang H.

    10/8/2022
    miR-551b is Associated with the Poor Prognosis and Malignant Development of Papillary Thyroid Cancer Through Regulating ERBB4.

    miR-551b is Associated with the Poor Prognosis and Malignant Development of Papillary Thyroid Cancer Through Regulating ERBB4.
    Wang J, Liu H.

    04/16/2022
    Tumor-suppressive microRNA-551b-3p targets H6PD to inhibit gallbladder cancer progression.

    Tumor-suppressive microRNA-551b-3p targets H6PD to inhibit gallbladder cancer progression.
    Ji T, Gao L, Yu Z.

    02/12/2022
    Decreased expression of miR-551b predicts poor prognosis and promotes tumorigenesis by targeting PTP4A3 in human colorectal cancer.

    Decreased expression of miR-551b predicts poor prognosis and promotes tumorigenesis by targeting PTP4A3 in human colorectal cancer.
    Sun HY, Qu ZC, Liu DM, Zhang W, Liu G, Zhu L.

    10/3/2020
    miRNA551b-3p Activates an Oncostatin Signaling Module for the Progression of Triple-Negative Breast Cancer.

    miRNA551b-3p Activates an Oncostatin Signaling Module for the Progression of Triple-Negative Breast Cancer.
    Parashar D, Geethadevi A, Aure MR, Mishra J, George J, Chen C, Mishra MK, Tahiri A, Zhao W, Nair B, Lu Y, Mangala LS, Rodriguez-Aguayo C, Lopez-Berestein G, Camara AKS, Liang M, Rader JS, Ramchandran R, You M, Sood AK, Kristensen VN, Mills GB, Pradeep S, Chaluvally-Raghavan P., Free PMC Article

    10/3/2020
    MicroRNA-551b-3p inhibits tumour growth of human cholangiocarcinoma by targeting Cyclin D1.

    MicroRNA-551b-3p inhibits tumour growth of human cholangiocarcinoma by targeting Cyclin D1.
    Chang W, Wang Y, Li W, Shi L, Geng Z., Free PMC Article

    09/5/2020
    Correlation analysis showed a positive correlation between the expression level of plasma miR-21-3p and miR-551-5p in severe acute pancreatitis patients

    [Expression and clinical significance of microRNA-21-3p and microRNA-551-5p in patients with acute pancreatitis].
    Wu K, Wang L, Fu G, Zheng Y.

    06/20/2020
    Study showed a significant inverse correlation between miR-551b expression level and the histological grading of the cervical intraepithelial neoplasia, suggesting that the miR-551b could play an important role as oncosuppressor in the different stages of cervical dysplasia through the control on cell cycle.

    MicroRNA-551b expression profile in low and high-grade cervical intraepithelial neoplasia.
    Lukic A, Di Properzio M, Carico E, De Vitis C, Giglio S, Bordi G, Caserta D, Mancini R.

    01/18/2020
    Circulating miR-551b-5p was a novel promising biomarker for the detection of gastric cancer

    Identification of diagnostic utility and molecular mechanisms of circulating miR-551b-5p in gastric cancer.
    Jiang X, Jiang M, Xu M, Xu J, Li Y.

    08/31/2019
    miR-551b-5p may help in the stratification of patient with acute pancreatitis as endothelial dysfunction during acute pancreatitis is reflected by levels of miR-551b-5p 12.

    Elevated Level of miR-551b-5p is Associated With Inflammation and Disease Progression in Patients With Severe Acute Pancreatitis.
    Zhang Y, Yan L, Han W.

    03/30/2019
    Data suggest that miR-551b-3p functions as a tumour suppressor gene in gastric cancer, and its function is regulated by long noncoding RNAs (lncRNAs) SMARCC2/miR-551b-3p/transmembrane protease, serine 4 protein (TMPRSS4) axis.

    Molecular mechanisms of lncRNA SMARCC2/miR-551b-3p/TMPRSS4 axis in gastric cancer.
    Yuan H, Chen Z, Bai S, Wei H, Wang Y, Ji R, Guo Q, Li Q, Ye Y, Wu J, Zhou Y, Qiao L.

    02/2/2019
    Low miR551b expression is associated with cholangiocarcinoma.

    A novel three‑miRNA signature predicts survival in cholangiocarcinoma based on RNA‑Seq data.
    Cao J, Sun L, Li J, Zhou C, Cheng L, Chen K, Yan B, Qian W, Ma Q, Duan W.

    11/3/2018
    These data indicate that miR-551b inhibits EMT and metastasis in GC by inhibiting ERBB4.

    miR-551b regulates epithelial-mesenchymal transition and metastasis of gastric cancer by inhibiting ERBB4 expression.
    Song G, Zhang H, Chen C, Gong L, Chen B, Zhao S, Shi J, Xu J, Ye Z., Free PMC Article

    04/14/2018
    In acute pancreatitis patients, a significant increase in miR-551-5p was observed when compared to control subjects.

    Serum levels of unique miR-551-5p and endothelial-specific miR-126a-5p allow discrimination of patients in the early phase of acute pancreatitis.
    Kuśnierz-Cabala B, Nowak E, Sporek M, Kowalik A, Kuźniewski M, Enguita FJ, Stępień E.

    05/8/2017
    The role of miR-551b in cell proliferation, invasion, and drug resistance of ovarian cancer

    Downregulation of Foxo3 and TRIM31 by miR-551b in side population promotes cell proliferation, invasion, and drug resistance of ovarian cancer.
    Wei Z, Liu Y, Wang Y, Zhang Y, Luo Q, Man X, Wei F, Yu X., Free PMC Article

    04/29/2017
    MicroRNA-551b is highly expressed in hematopoietic stem cells and can serve as biomarker for relapse and poor prognosis in acute myeloid leukemia.

    MicroRNA-551b is highly expressed in hematopoietic stem cells and a biomarker for relapse and poor prognosis in acute myeloid leukemia.
    de Leeuw DC, Verhagen HJ, Denkers F, Kavelaars FG, Valk PJ, Schuurhuis GJ, Ossenkoppele GJ, Smit L.

    07/30/2016
    our results establish a pathway consisting of miR-551b/catalase/ROS that results in MUC1 overexpression, and intervention against this pathway could be exploited to overcome acquired chemoresistance.

    A signaling pathway consisting of miR-551b, catalase and MUC1 contributes to acquired apoptosis resistance and chemoresistance.
    Xu X, Wells A, Padilla MT, Kato K, Kim KC, Lin Y., Free PMC Article

    03/21/2015
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