| MicroRNA-592 serves as a novel tumor suppressor in Uveal melanoma: bioinformatics analysis and in vitro cell function verification. | MicroRNA-592 serves as a novel tumor suppressor in Uveal melanoma: bioinformatics analysis and in vitro cell function verification.
Lei P, Xue L, Wu Y, Zhong J., Free PMC Article | 05/8/2023 |
| MicroRNA-592 Inhibits the Growth of Ovarian Cancer Cells by Targeting ERBB3. | MicroRNA-592 Inhibits the Growth of Ovarian Cancer Cells by Targeting ERBB3.
Jin Q, Zhang N, Zhan Y, Xu X, Han C, Zhao H, Hu X, Tang H, Wu Y., Free PMC Article | 03/19/2023 |
| MiR-592 activates the mTOR kinase, ERK1/ERK2 kinase signaling and imparts neuronal differentiation signature characteristic of Group 4 medulloblastoma. | MiR-592 activates the mTOR kinase, ERK1/ERK2 kinase signaling and imparts neuronal differentiation signature characteristic of Group 4 medulloblastoma.
Paul R, Bapat P, Deogharkar A, Kazi S, Singh SKV, Gupta T, Jalali R, Sridhar E, Moiyadi A, Shetty P, Shirsat NV. | 04/16/2022 |
| The regulation of microRNA in each of cancer stage from two different ethnicities as potential biomarker for breast cancer. | The regulation of microRNA in each of cancer stage from two different ethnicities as potential biomarker for breast cancer.
Ramanto KN, Widianto KJ, Wibowo SSH, Agustriawan D. | 09/18/2021 |
| MicroRNA592 promotes cell proliferation, migration and invasion in colorectal cancer by directly targeting SPARC. | MicroRNA‑592 promotes cell proliferation, migration and invasion in colorectal cancer by directly targeting SPARC.
Pan Z, Xie R, Song W, Gao C., Free PMC Article | 05/15/2021 |
| LncRNA WTAPP1 promotes proliferation of laryngeal carcinoma cells through regulating microRNA-592. | LncRNA WTAPP1 promotes proliferation of laryngeal carcinoma cells through regulating microRNA-592.
Shi XY, Lin JJ, Ge XJ, Shi Y. | 05/8/2021 |
| miR592 acts as an oncogene and promotes medullary thyroid cancer tumorigenesis by targeting cyclindependent kinase 8. | miR‑592 acts as an oncogene and promotes medullary thyroid cancer tumorigenesis by targeting cyclin‑dependent kinase 8.
Liu T, Meng J, Zhang Y., Free PMC Article | 05/1/2021 |
| The Potential Role of Selected miRNA in Uveal Melanoma Primary Tumors as Early Biomarkers of Disease Progression. | The Potential Role of Selected miRNA in Uveal Melanoma Primary Tumors as Early Biomarkers of Disease Progression.
Wróblewska JP, Lach MS, Ustaszewski A, Kulcenty K, Ibbs M, Jagiełło I, Suchorska WM, Marszałek A., Free PMC Article | 02/2/2021 |
| findings suggest that miR-592 acted as a tumor suppressor by targeting ROCK1 and may serve as a potential biomarker in acute myeloid leukemia | MiR-592 functions as a tumor suppressor in acute myeloid leukemia by targeting ROCK1 and predicts patients' prognosis.
Xu Y, Li K, Wang SB, Yang SG. | 08/1/2020 |
| The results indicated that the NEAT1/miR592/NOVA1 pathway may play regulatory roles in thyroid cancer malignancy in vitro and in vivo. Our findings may provide novel insight into the pathogenesis of thyroid cancer. | MicroRNA-592 suppresses the malignant phenotypes of thyroid cancer by regulating lncRNA NEAT1 and downregulating NOVA1.
Luo Y, Hao T, Zhang J, Zhang M, Sun P, Wu L. | 02/8/2020 |
| The results of this study showed that miR-592 targets the ROCK1 transcript and suppresses glioma cell growth and invasive growth, thereby providing | MiR-592 suppresses the development of glioma by regulating Rho-associated protein kinase.
Gao S, Chen J, Wang Y, Zhong Y, Dai Q, Wang Q, Tu J. | 04/13/2019 |
| Overexpression of miR-592 promotes GC proliferation, migration, and invasion and induces the EMT via the PI3K/AKT and MAPK/ERK signaling pathways by inhibiting Spry2, suggesting a potential therapeutic target for Gastric cancer. | MiR-592 Promotes Gastric Cancer Proliferation, Migration, and Invasion Through the PI3K/AKT and MAPK/ERK Signaling Pathways by Targeting Spry2.
He Y, Ge Y, Jiang M, Zhou J, Luo D, Fan H, Shi L, Lin L, Yang L. | 08/18/2018 |
| these data suggest that miR-592 may exert it suppressive role in breast cancer, at least in part, by targeting TGFbeta-2, and that miR-592 may be a novel target for breast cancer treatment | Suppressive role of miR-592 in breast cancer by repressing TGF-β2.
Hou W, Zhang H, Bai X, Liu X, Yu Y, Song L, Du Y. | 07/21/2018 |
| our clinical data and functional studies suggest that miR-592 is a new robust inhibitor of the Warburg effect and a promising therapeutic target for hepatocellular carcinoma treatment | miR-592/WSB1/HIF-1α axis inhibits glycolytic metabolism to decrease hepatocellular carcinoma growth.
Jia YY, Zhao JY, Li BL, Gao K, Song Y, Liu MY, Yang XJ, Xue Y, Wen AD, Shi L., Free PMC Article | 01/13/2018 |
| We developed a miRNA expression signature that may be predictive for the risk of distant relapse in early stage CC and confirmed previously reported association between miR-592 expression and MMR status. | Prognostic value of 5-microRNA based signature in T2-T3N0 colon cancer.
Bobowicz M, Skrzypski M, Czapiewski P, Marczyk M, Maciejewska A, Jankowski M, Szulgo-Paczkowska A, Zegarski W, Pawłowski R, Polańska J, Biernat W, Jaśkiewicz J, Jassem J., Free PMC Article | 09/2/2017 |
| mechanistic investigations defined insulin-like growth factor binding protein 2 (IGFBP2)as a direct and functional downstream target of microRNA-592, which was involved in the microRNA-592-mediated tumor-suppressive effects in glioma cells. | MiR-592 functions as a tumor suppressor in glioma by targeting IGFBP2.
Peng T, Zhou L, Qi H, Wang G, Luan Y, Zuo L. | 07/29/2017 |
| These data suggest that miR-592 may promote the progression and metastasis, in part, by targeting FoxO3A in colorectal cancer | An oncogenic role of miR-592 in tumorigenesis of human colorectal cancer by targeting Forkhead Box O3A (FoxO3A).
Fu Q, Du Y, Yang C, Zhang D, Zhang N, Liu X, Cho WC, Yang Y. | 06/10/2017 |
| miR-592 targets DEK transcript and suppresses hepatocellular carcinoma cell growth | MicroRNA-592 targets DEK oncogene and suppresses cell growth in the hepatocellular carcinoma cell line HepG2.
Li X, Zhang W, Zhou L, Yue D, Su X., Free PMC Article | 10/8/2016 |
| The expression of miR-592 and its effects on LHCG receptors in patients with polycystic ovary syndrome and normal controls are described. | miRNA-592 is downregulated and may target LHCGR in polycystic ovary syndrome patients.
Song J, Luo S, Li SW. | 09/24/2016 |
| miR-592 functioned as a novel and potential carcinogen-initiated and metastasis-related biomarker in colorectal cancer. | Up-regulation of miR-592 correlates with tumor progression and poor prognosis in patients with colorectal cancer.
Liu M, Zhi Q, Wang W, Zhang Q, Fang T, Ma Q. | 10/24/2015 |
| miR-552 and miR-592 were overexpressed in primary colorectal cancer relative to primary lung adenocarcinomas | miR-592 and miR-552 can distinguish between primary lung adenocarcinoma and colorectal cancer metastases in the lung.
Kim HK, Lim NJ, Jang SG, Lee GK. | 06/28/2014 |