| MicroRNA-646 inhibits the proliferation of ovarian granulosa cells via insulin-like growth factor 1 (IGF-1) in polycystic ovarian syndrome (PCOS). | MicroRNA-646 inhibits the proliferation of ovarian granulosa cells via insulin-like growth factor 1 (IGF-1) in polycystic ovarian syndrome (PCOS).
Lu J, Xuan F, Chen A, Jin R, Zhou W, Ye Y, Ren Y. | 09/15/2023 |
| Down-Regulation of circCOL1A2 Suppresses the Dysfunction of Diabetes-Related Retinal Microvascular Endothelial Cells via miR-646/FGF7 Axis. | Down-Regulation of circCOL1A2 Suppresses the Dysfunction of Diabetes-Related Retinal Microvascular Endothelial Cells via miR-646/FGF7 Axis.
Cao H, Xu X, Wang K, Li C. | 10/22/2022 |
| Circ_0001955 Acts as a miR-646 Sponge to Promote the Proliferation, Metastasis and Angiogenesis of Hepatocellular Carcinoma. | Circ_0001955 Acts as a miR-646 Sponge to Promote the Proliferation, Metastasis and Angiogenesis of Hepatocellular Carcinoma.
Li X, Lv J, Hou L, Guo X. | 06/11/2022 |
| Circ-PKD2 promotes Atg13-mediated autophagy by inhibiting miR-646 to increase the sensitivity of cisplatin in oral squamous cell carcinomas. | Circ-PKD2 promotes Atg13-mediated autophagy by inhibiting miR-646 to increase the sensitivity of cisplatin in oral squamous cell carcinomas.
Gao L, Zhang Q, Li S, Zheng J, Ren W, Zhi K., Free PMC Article | 04/16/2022 |
| Circ_0016760 accelerates non-small-cell lung cancer progression through miR-646/AKT3 signaling in vivo and in vitro. | Circ_0016760 accelerates non-small-cell lung cancer progression through miR-646/AKT3 signaling in vivo and in vitro.
Chen S, Zhou L, Ran R, Huang J, Zheng Y, Xing M, Cai Y., Free PMC Article | 02/5/2022 |
| hsa_circ_0001610 knockdown modulates miR-646-STAT3 axis to suppress endometrial carcinoma progression. | hsa_circ_0001610 knockdown modulates miR-646-STAT3 axis to suppress endometrial carcinoma progression.
Wang B, Lu Y, Feng E. | 01/22/2022 |
| MiR-646 regulates proliferation and migration of laryngeal carcinoma through the PI3K/AKT pathway via targeting GPX1. | MiR-646 regulates proliferation and migration of laryngeal carcinoma through the PI3K/AKT pathway via targeting GPX1.
Yuan X, Liu Y, Chen E, Wang J, Deng S, Chen P, Wang X, Deng S. | 10/9/2021 |
| Oxidative Stress-Induced circHBEGF Promotes Extracellular Matrix Production via Regulating miR-646/EGFR in Human Trabecular Meshwork Cells. | Oxidative Stress-Induced circHBEGF Promotes Extracellular Matrix Production via Regulating miR-646/EGFR in Human Trabecular Meshwork Cells.
Shen W, Wang C, Huang B., Free PMC Article | 09/11/2021 |
| MiR-646 prevents proliferation and progression of human breast cancer cell lines by suppressing HDAC2 expression. | MiR-646 prevents proliferation and progression of human breast cancer cell lines by suppressing HDAC2 expression.
Darvishi N, Rahimi K, Mansouri K, Fathi F, Menbari MN, Mohammadi G, Abdi M. | 07/17/2021 |
| Circular RNA has_circ_0000527 participates in proliferation, invasion and migration of retinoblastoma cells via miR-646/BCL-2 axis. | Circular RNA has_circ_0000527 participates in proliferation, invasion and migration of retinoblastoma cells via miR-646/BCL-2 axis.
Chen NN, Chao DL, Li XG. | 05/29/2021 |
| MiR-646 suppresses proliferation and metastasis of non-small cell lung cancer by repressing FGF2 and CCND2. | MiR-646 suppresses proliferation and metastasis of non-small cell lung cancer by repressing FGF2 and CCND2.
Wang J, Shu H, Guo S., Free PMC Article | 05/22/2021 |
| CircRNA WHSC1 targets the miR-646/NPM1 pathway to promote the development of endometrial cancer. | CircRNA WHSC1 targets the miR-646/NPM1 pathway to promote the development of endometrial cancer.
Liu Y, Chen S, Zong ZH, Guan X, Zhao Y., Free PMC Article | 05/1/2021 |
| circRNA circ-CCND1 promotes the proliferation of laryngeal squamous cell carcinoma through elevating CCND1 expression via interacting with HuR and miR-646. | circRNA circ-CCND1 promotes the proliferation of laryngeal squamous cell carcinoma through elevating CCND1 expression via interacting with HuR and miR-646.
Zang Y, Li J, Wan B, Tai Y., Free PMC Article | 05/1/2021 |
| Long Noncoding MT1JP Enhanced the Inhibitory Effects of miR-646 on FGF2 in Osteosarcoma. | Long Noncoding MT1JP Enhanced the Inhibitory Effects of miR-646 on FGF2 in Osteosarcoma.
Yang L, Liu G, Xiao S, Wang L, Liu X, Tan Q, Li Z. | 01/23/2021 |
| Androgen receptor reverses the oncometabolite R-2-hydroxyglutarate-induced prostate cancer cell invasion via suppressing the circRNA-51217/miRNA-646/TGFbeta1/p-Smad2/3 signaling. | Androgen receptor reverses the oncometabolite R-2-hydroxyglutarate-induced prostate cancer cell invasion via suppressing the circRNA-51217/miRNA-646/TGFβ1/p-Smad2/3 signaling.
Xu H, Sun Y, You B, Huang CP, Ye D, Chang C. | 08/15/2020 |
| miR-646 acted as a target of hsa_circ_0041795 and VEGFC was a direct target of miR-646. | hsa_circ_0041795 contributes to human retinal pigment epithelial cells (ARPE 19) injury induced by high glucose via sponging miR-646 and activating VEGFC.
Sun H, Kang X. | 05/23/2020 |
| miR-646 is a key negative regulator of EGFR pathway in lung cancer. | miR-646 is a key negative regulator of EGFR pathway in lung cancer.
Pan Y, Chen Y, Ma D, Ji Z, Cao F, Chen Z, Ning Y, Bai C. | 04/22/2019 |
| Dysregulated miR-646 and MIIP expression was correlated with advanced tumor stage, lymphatic invasion, metastasis and shorter overall survival in Pancreatic cancer patients. | MiRNA-646-mediated reciprocal repression between HIF-1α and MIIP contributes to tumorigenesis of pancreatic cancer.
Niu Y, Jin Y, Deng SC, Deng SJ, Zhu S, Liu Y, Li X, He C, Liu ML, Zeng Z, Chen HY, Zhong JX, Ye Z, Wang CY, Zhao G. | 03/30/2019 |
| HOTAIR could regulate NPM1 by interacting with miR-646, thereby governing the viability, migration, and invasion of endometrial cancer cells. | Long noncoding RNA HOTAIR mediates the estrogen-induced metastasis of endometrial cancer cells via the miR-646/NPM1 axis.
Zhou YX, Wang C, Mao LW, Wang YL, Xia LQ, Zhao W, Shen J, Chen J. | 03/9/2019 |
| MiR-646 expression was downregulated in gastric cancer tissues compared with adjacent normal tissues. Low miR-646 expression is associated with malignant progression. miR-646 inhibited gastric cancer cell proliferation and the epithelial-mesenchymal transition progression in gastric cancer cells by targeting FOXK1. | MiR-646 inhibited cell proliferation and EMT-induced metastasis by targeting FOXK1 in gastric cancer.
Zhang P, Tang WM, Zhang H, Li YQ, Peng Y, Wang J, Liu GN, Huang XT, Zhao JJ, Li G, Li AM, Bai Y, Chen Y, Ren YX, Li GX, Wang YD, Liu SD, Wang JD., Free PMC Article | 09/9/2017 |
| miR-646 SNP rs6513497 may contribute to the susceptibility of HCC. | Association between a variant in microRNA-646 and the susceptibility to hepatocellular carcinoma in a large-scale population.
Wang R, Zhang J, Jiang W, Ma Y, Li W, Jin B, Hu H, Wang J, Liu Y, Liu J., Free PMC Article | 05/30/2015 |
| Observational study and genome-wide association study of gene-disease association. (HuGE Navigator) | A three-stage genome-wide association study of general cognitive ability: hunting the small effects.
Davis OS, Butcher LM, Docherty SJ, Meaburn EL, Curtis CJ, Simpson MA, Schalkwyk LC, Plomin R., Free PMC Article | 04/7/2010 |