Multidimensional data analysis revealed thyroiditis-associated TCF19 SNP rs2073724 as a highly ranked protective variant in thyroid cancer. | Multidimensional data analysis revealed thyroiditis-associated TCF19 SNP rs2073724 as a highly ranked protective variant in thyroid cancer. Ruan X, Liu Y, Wu S, Fu G, Tao M, Huang Y, Li D, Wei S, Gao M, Guo S, Ning J, Zheng X., Free PMC Article | 05/7/2024 |
Genetic variants associated with expression of TCF19 contribute to the risk of head and neck cancer in Chinese population. | Genetic variants associated with expression of TCF19 contribute to the risk of head and neck cancer in Chinese population. Ji P, Chang J, Wei X, Song X, Yuan H, Gong L, Li Y, Ding D, Zhang E, Yan C, Zhu M, Miao X, Wu C, Jin G, Hu Z, Shen H, Ma H. | 05/14/2022 |
Exon and intron sharing in opposite direction-an undocumented phenomenon in human genome-between Pou5f1 and Tcf19 genes. | Exon and intron sharing in opposite direction-an undocumented phenomenon in human genome-between Pou5f1 and Tcf19 genes. Mehravar M, Ghaemimanesh F, Poursani EM., Free PMC Article | 10/9/2021 |
TCF19 and p53 regulate transcription of TIGAR and SCO2 in HCC for mitochondrial energy metabolism and stress adaptation. | TCF19 and p53 regulate transcription of TIGAR and SCO2 in HCC for mitochondrial energy metabolism and stress adaptation. Mondal P, Gadad SS, Adhikari S, Ramos EI, Sen S, Prasad P, Das C. | 08/28/2021 |
TCF19 aggravates the malignant progression of colorectal cancer by negatively regulating WWC1. | TCF19 aggravates the malignant progression of colorectal cancer by negatively regulating WWC1. Du WB, Huang Z, Luo L, Tong SP, Li HQ, Li X, Tong JH, Yao YL, Zhang WB, Meng Y. | 02/13/2021 |
TCF19 Promotes Cell Proliferation through Binding to the Histone H3K4me3 Mark. | TCF19 Promotes Cell Proliferation through Binding to the Histone H3K4me3 Mark. Mondal P, Sen S, Klein BJ, Tiwary N, Gadad SS, Kutateladze TG, Roy S, Das C. | 08/22/2020 |
AKT/FOXO1 signaling is essential for TCF19 influence on hepatocellular carcinoma progression | TCF19 enhances cell proliferation in hepatocellular carcinoma by activating the ATK/FOXO1 signaling pathway. Zeng CX, Fu SB, Feng WS, Zhao JY, Li FX, Gao P. | 08/17/2019 |
Data suggest TCF19 interacts with histone 3 lysine 4 trimethylation through its plant homeodomain finger; TCF19 expression appears to regulate gluconeogenesis in hepatocytes; TCF19 interacts with CHD4 causing NuRD complex recruitment to gene promoters of enzymes involved in gluconeogenesis. (TCF19 = transcription factor 19; CHD4 = chromodomain helicase DNA binding protein 4; NuRD = nucleosome-remodeling-deacetylase) | Transcription factor 19 interacts with histone 3 lysine 4 trimethylation and controls gluconeogenesis via the nucleosome-remodeling-deacetylase complex. Sen S, Sanyal S, Srivastava DK, Dasgupta D, Roy S, Das C., Free PMC Article | 01/27/2018 |
Genome association studies identified TCF19 as a new risk-associated loci for chronic hepatitis B on the HLA region of chromosome 6. | A genome-wide association study identified new variants associated with the risk of chronic hepatitis B. Kim YJ, Kim HY, Lee JH, Yu SJ, Yoon JH, Lee HS, Kim CY, Cheong JY, Cho SW, Park NH, Park BL, Namgoong S, Kim LH, Cheong HS, Shin HD. | 04/26/2014 |
Data shows increased apoptosis and susceptibility to endoplasmic reticulum (ER) stress after Tcf19 knockdown. | Tcf19 is a novel islet factor necessary for proliferation and survival in the INS-1 β-cell line. Krautkramer KA, Linnemann AK, Fontaine DA, Whillock AL, Harris TW, Schleis GJ, Truchan NA, Marty-Santos L, Lavine JA, Cleaver O, Kimple ME, Davis DB, Krautkramer KA, Linnemann AK, Fontaine DA, Whillock AL, Harris TW, Schleis GJ, Truchan NA, Marty-Santos L, Lavine JA, Cleaver O, Kimple ME, Davis DB., Free PMC Articles: PMC3761170, PMC3761170 | 03/1/2014 |
Knockdown of Tcf19 reduces proliferation and increases apoptosis. Tcf19 is found in pancreatic islets in mouse and human. | Tcf19 is a novel islet factor necessary for proliferation and survival in the INS-1 β-cell line. Krautkramer KA, Linnemann AK, Fontaine DA, Whillock AL, Harris TW, Schleis GJ, Truchan NA, Marty-Santos L, Lavine JA, Cleaver O, Kimple ME, Davis DB, Krautkramer KA, Linnemann AK, Fontaine DA, Whillock AL, Harris TW, Schleis GJ, Truchan NA, Marty-Santos L, Lavine JA, Cleaver O, Kimple ME, Davis DB., Free PMC Articles: PMC3761170, PMC3761170 | 02/5/2014 |
A linkage disequilibrium analysis established TCF19, POU5F1, CCHCR1 and PSORS1C1 as potential causal genes for the type 1 diabetes. | Conditional meta-analysis stratifying on detailed HLA genotypes identifies a novel type 1 diabetes locus around TCF19 in the MHC. Cheung YH, Watkinson J, Anastassiou D., Free PMC Article | 02/12/2011 |
Observational study of gene-disease association. (HuGE Navigator) | See all PubMed (2) articlesExamination of genetic polymorphisms in newborns for signatures of sex-specific prenatal selection. Ucisik-Akkaya E, Davis CF, Do TN, Morrison BA, Stemmer SM, Amadio WJ, Dorak MT. High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions. Barcellos LF, May SL, Ramsay PP, Quach HL, Lane JA, Nititham J, Noble JA, Taylor KE, Quach DL, Chung SA, Kelly JA, Moser KL, Behrens TW, Seldin MF, Thomson G, Harley JB, Gaffney PM, Criswell LA. | 01/20/2010 |