Transcription factor 21 rs12190287 polymorphism is related to stable angina and ST elevation myocardial infarction in a Chinese Population. | Transcription factor 21 rs12190287 polymorphism is related to stable angina and ST elevation myocardial infarction in a Chinese Population. Yu TH, Lee TL, Tsai IT, Hsuan CF, Wang CP, Lu YC, Tang WH, Wei CT, Chung FM, Lee YJ, Wu CC., Free PMC Article | 02/16/2024 |
TCF21 rs2327429 and TCF21 rs12190287 are associated with colorectal cancer in a Chinese population. | TCF21 rs2327429 and TCF21 rs12190287 are associated with colorectal cancer in a Chinese population. Wang JG, Jin XF, Huang YM, Xu ZF, Huang SJ, Zhu Y, Ai L, Hang T. | 01/16/2024 |
Transcription factor 21 gene and prognosis in a coronary population. | Transcription factor 21 gene and prognosis in a coronary population. Santos MR, Mendonça MI, Temtem M, Sá D, Sousa AC, Freitas S, Rodrigues M, Borges S, Guerra G, Ornelas I, Drumond A, Palma Dos Reis R. | 11/10/2023 |
Transcription factor 21 accelerates vascular calcification in mice by activating the IL-6/STAT3 signaling pathway and the interplay between VSMCs and ECs. | Transcription factor 21 accelerates vascular calcification in mice by activating the IL-6/STAT3 signaling pathway and the interplay between VSMCs and ECs. Zhao XK, Zhu MM, Wang SN, Zhang TT, Wei XN, Wang CY, Zheng J, Zhu WY, Jiang MX, Xu SW, Yang XX, Duan YJ, Zhang BC, Han JH, Miao QR, Hu H, Chen YL., Free PMC Article | 09/12/2023 |
N-type calcium channel v2.2 is a target of TCF21 in adrenocortical carcinomas. | N-type calcium channel v2.2 is a target of TCF21 in adrenocortical carcinomas. Passaia BDS, Kremer JL, Fragoso MCV, Lotfi CFP. | 08/20/2022 |
Immunohistological score of transcription factor 21 had a positive correlation with its urinary excretion and proteinuria in immunoglobulin A nephropathy. | Immunohistological score of transcription factor 21 had a positive correlation with its urinary excretion and proteinuria in immunoglobulin A nephropathy. Takahashi-Kobayashi M, Usui J, Yaguchi M, Yamazaki S, Kawamura T, Kaneko S, Seshan SV, Yamagata K. | 04/2/2022 |
Relationships among Immune Score, <em>TCF21</em> Methylation, Risk-factor Level, and Prognosis in Prostate Cancer. | Relationships among Immune Score, <em>TCF21</em> Methylation, Risk-factor Level, and Prognosis in Prostate Cancer. Zhang W, Huang Z, Xin J. | 02/19/2022 |
Increased SUMOylation of TCF21 improves its stability and function in human endometriotic stromal cellsdagger. | Increased SUMOylation of TCF21 improves its stability and function in human endometriotic stromal cells†. Zhu J, Wu P, Zeng C, Xue Q. | 12/25/2021 |
TCF21 regulates miR-10a-5p/LIN28B signaling to block the proliferation and invasion of melanoma cells. | TCF21 regulates miR-10a-5p/LIN28B signaling to block the proliferation and invasion of melanoma cells. Zhu H, Kang M, Bai X., Free PMC Article | 12/11/2021 |
Studies on the Role of the Transcription Factor Tcf21 in the Transdifferentiation of Parietal Epithelial Cells into Podocyte-Like Cells. | Studies on the Role of the Transcription Factor Tcf21 in the Transdifferentiation of Parietal Epithelial Cells into Podocyte-Like Cells. Kliewe F, Kuss AW, Siegerist F, Schröder S, Schordan S, Artelt N, Kindt F, Amann K, Lindenmeyer MT, Endlich K, Endlich N. | 08/28/2021 |
TCF21 Promotes Luminal-Like Differentiation and Suppresses Metastasis in Bladder Cancer. | TCF21 Promotes Luminal-Like Differentiation and Suppresses Metastasis in Bladder Cancer. Mokkapati S, Porten SP, Narayan VM, Lim AH, Jayaratna IS, Roth B, Cheng T, Navai N, Wszolek M, Melquist J, Manyam G, Choi W, Broom B, Pretzsch S, Czerniak B, McConkey DJ, Dinney CPN. | 06/5/2021 |
Molecular mechanisms of coronary disease revealed using quantitative trait loci for TCF21 binding, chromatin accessibility, and chromosomal looping. | Molecular mechanisms of coronary disease revealed using quantitative trait loci for TCF21 binding, chromatin accessibility, and chromosomal looping. Zhao Q, Dacre M, Nguyen T, Pjanic M, Liu B, Iyer D, Cheng P, Wirka R, Kim JB, Fraser HB, Quertermous T., Free PMC Article | 04/3/2021 |
Distinct fibroblast functional states drive clinical outcomes in ovarian cancer and are regulated by TCF21. | Distinct fibroblast functional states drive clinical outcomes in ovarian cancer and are regulated by TCF21. Hussain A, Voisin V, Poon S, Karamboulas C, Bui NHB, Meens J, Dmytryshyn J, Ho VW, Tang KH, Paterson J, Clarke BA, Bernardini MQ, Bader GD, Neel BG, Ailles LE., Free PMC Article | 03/6/2021 |
Transcription factor 21 expression in injured podocytes of glomerular diseases. | Transcription factor 21 expression in injured podocytes of glomerular diseases. Usui J, Yaguchi M, Yamazaki S, Takahashi-Kobayashi M, Kawamura T, Kaneko S, Seshan SV, Ronco P, Yamagata K., Free PMC Article | 12/19/2020 |
Functional balance between Tcf21-Slug defines cellular plasticity and migratory modalities in high grade serous ovarian cancer cell lines. | Functional balance between Tcf21-Slug defines cellular plasticity and migratory modalities in high grade serous ovarian cancer cell lines. Varankar SS, More M, Abraham A, Pansare K, Kumar B, Narayanan NJ, Jolly MK, Mali AM, Bapat SA. | 10/31/2020 |
Transfer of miR-25-3p by CHB-PNALT-Exo promoted the development of liver cancer by inhibiting the co-expression of TCF21 and HHIP. | Exosomes secreted by chronic hepatitis B patients with PNALT and liver inflammation grade ≥ A2 promoted the progression of liver cancer by transferring miR-25-3p to inhibit the co-expression of TCF21 and HHIP. Ouyang Y, Tang Y, Fu L, Peng S, Wu W, Tan D, Fu X., Free PMC Article | 08/12/2020 |
Data show that transcription factor 21 (TCF21) directly interferes with formation and function of the myocardin (MYOCD)-serum response factor (SRF) complex. | Coronary Disease-Associated Gene TCF21 Inhibits Smooth Muscle Cell Differentiation by Blocking the Myocardin-Serum Response Factor Pathway. Nagao M, Lyu Q, Zhao Q, Wirka RC, Bagga J, Nguyen T, Cheng P, Kim JB, Pjanic M, Miano JM, Quertermous T., Free PMC Article | 08/1/2020 |
High TCF1 expression is associated with the pathogenesis of Fibrosis in Endometriosis. | Involvement of Transcription Factor 21 in the Pathogenesis of Fibrosis in Endometriosis. Ganieva U, Nakamura T, Osuka S, Bayasula, Nakanishi N, Kasahara Y, Takasaki N, Muraoka A, Hayashi S, Nagai T, Murase T, Goto M, Iwase A, Kikkawa F. | 04/25/2020 |
Transcription factor 21 (TCF21) is downregulated in Cholangiocarcinoma (CCA) tissues or cells. | TCF21 inhibits tumor-associated angiogenesis and suppresses the growth of cholangiocarcinoma by targeting PI3K/Akt and ERK signaling. Duan HX, Li BW, Zhuang X, Wang LT, Cao Q, Tan LH, Qu GF, Xiao S. | 02/15/2020 |
TCF21 interacts with JUN to regulate expression of two presumptive causal coronary disease genes, SMAD3 and CDKN2B-AS1. | TCF21 and AP-1 interact through epigenetic modifications to regulate coronary artery disease gene expression. Zhao Q, Wirka R, Nguyen T, Nagao M, Cheng P, Miller CL, Kim JB, Pjanic M, Quertermous T., Free PMC Article | 12/28/2019 |
hsa_circ_100395 regulates lung cancer cell proliferation, migration and invasion through modulating miR-1228/TCF21 pathway. | CircRNA hsa_circ_100395 regulates miR-1228/TCF21 pathway to inhibit lung cancer progression. Chen D, Ma W, Ke Z, Xie F., Free PMC Article | 12/7/2019 |
Authors propose that the pro-differentiation action of SMAD3 inhibits dedifferentiation that is required for HCASMC to expand and stabilize disease plaque as they respond to vascular stresses, counteracting the protective dedifferentiating activity of TCF21 and promoting disease risk. | Coronary artery disease genes SMAD3 and TCF21 promote opposing interactive genetic programs that regulate smooth muscle cell differentiation and disease risk. Iyer D, Zhao Q, Wirka R, Naravane A, Nguyen T, Liu B, Nagao M, Cheng P, Miller CL, Kim JB, Pjanic M, Quertermous T., Free PMC Article | 02/16/2019 |
The study revealed that restoration of TCF21 expression in 786-O clear cell renal cell carcinoma cell line results in decreased clonogenic proliferation and migration. | TCF21 hypermethylation regulates renal tumor cell clonogenic proliferation and migration. Gooskens SL, Klasson TD, Gremmels H, Logister I, Pieters R, Perlman EJ, Giles RH, van den Heuvel-Eibrink MM., Free PMC Article | 02/2/2019 |
TCF21 inhibits gastric cancer growth and chemoresistance possibly through the AKT signaling pathway | TCF21 inhibits proliferation and chemoresistance through the AKT pathway in human gastric cancer. Yang Z, Jiang X, Li D, Dong Q, Zhao H, Jiang X. | 12/22/2018 |
we concluded that decreased mRNA expression of TCF21 is a predictor for poor prognosis in patients with lung adenocarcinoma. | Prognostic significance of TCF21 mRNA expression in patients with lung adenocarcinoma. Xiao J, Liu A, Lu X, Chen X, Li W, He S, He B, Chen Q., Free PMC Article | 12/22/2018 |