| Neuronal BST2: A Pruritic Mediator alongside Protease-Activated Receptor 2 in the IL-27-Driven Itch Pathway. | Neuronal BST2: A Pruritic Mediator alongside Protease-Activated Receptor 2 in the IL-27-Driven Itch Pathway.
Li Y, Chen W, Zhu X, Mei H, Steinhoff M, Buddenkotte J, Wang J, Zhang W, Li Z, Dai X, Shan C, Wang J, Meng J. | 07/23/2024 |
| Promotion of BST2 expression by the transcription factor IRF6 affects the progression of endometriosis. | Promotion of BST2 expression by the transcription factor IRF6 affects the progression of endometriosis.
Li J, He Y, Qu Y, Ren C, Wang X, Cheng Y, Sun L, Zhang X, Zhang G., Free PMC Article | 05/13/2023 |
| The roles of BST-2 in murine B cell development and on virus propagation. | The roles of BST-2 in murine B cell development and on virus propagation.
Urata S, Yamaguchi S, Nambu A, Sudo K, Nakae S, Yasuda J. | 03/9/2023 |
| BST2, a Novel Inhibitory Receptor, Is Involved in NK Cell Cytotoxicity through Its Cytoplasmic Tail Domain. | BST2, a Novel Inhibitory Receptor, Is Involved in NK Cell Cytotoxicity through Its Cytoplasmic Tail Domain.
Oh J, Yi E, Jeong SK, Park S, Park SH., Free PMC Article | 10/22/2022 |
| Murine BST2/tetherin promotes measles virus infection of neurons. | Murine BST2/tetherin promotes measles virus infection of neurons.
Miller KD, Matullo C, Williams R, Jones CB, Rall GF., Free PMC Article | 01/8/2022 |
| Interferon Gamma Mediates Hematopoietic Stem Cell Activation and Niche Relocalization through BST2. | Interferon Gamma Mediates Hematopoietic Stem Cell Activation and Niche Relocalization through BST2.
Florez MA, Matatall KA, Jeong Y, Ortinau L, Shafer PW, Lynch AM, Jaksik R, Kimmel M, Park D, King KY., Free PMC Article | 12/25/2021 |
| CD317 puts the brakes on dendritic cell trafficking to the CNS. | CD317 puts the brakes on dendritic cell trafficking to the CNS.
Barnes SE, Han MH., Free PMC Article | 12/4/2021 |
| BST-2/Tetherin is involved in BAFF-enhanced proliferation and survival via canonical NF-kappaB signaling in neoplastic B-lymphoid cells. | BST-2/Tetherin is involved in BAFF-enhanced proliferation and survival via canonical NF-κB signaling in neoplastic B-lymphoid cells.
Fu J, Shi H, Zhan T, Li H, Ye L, Xie L, Wang Z, Wang B, Zheng L. | 05/1/2021 |
| contain the spread of herpes simplex virus type 1 in vivo, STING-dependent signaling leads to the upregulation of tetherin, a viral restriction factor | A STING-dependent innate-sensing pathway mediates resistance to corneal HSV-1 infection via upregulation of the antiviral effector tetherin.
Royer DJ, Carr DJ., Free PMC Article | 11/4/2017 |
| Tetherin-mediated retention of R-defective virions on the cell surface could enhance syncytium formation. | Mouse tetherin enhances moloney murine leukemia virus-induced syncytium formation.
Kim HS, Han SY, Jung YT. | 07/1/2017 |
| Bone marrow stromal antigen 2-mediated dendritic cell activation as a critical mechanism for how Tetherin influenced retrovirus cell-mediated immune responses that subsequently inhibited retrovirus replication in vivo. | Tetherin/BST-2 promotes dendritic cell activation and function during acute retrovirus infection.
Li SX, Barrett BS, Guo K, Kassiotis G, Hasenkrug KJ, Dittmer U, Gibbert K, Santiago ML., Free PMC Article | 01/14/2017 |
| BST-2 does not have a role in modulating Influenza A Virus in the mouse model of infection | Endogenous Murine BST-2/Tetherin Is Not a Major Restriction Factor of Influenza A Virus Infection.
Londrigan SL, Tate MD, Job ER, Moffat JM, Wakim LM, Gonelli CA, Purcell DF, Brooks AG, Villadangos JA, Reading PC, Mintern JD., Free PMC Article | 07/2/2016 |
| Although Bst2 prevented Measles virus (MV) release from nonneuronal cells, its deletion had no effect on viral pathogenesis in MV-challenged mice. | Bst2/Tetherin Is Induced in Neurons by Type I Interferon and Viral Infection but Is Dispensable for Protection against Neurotropic Viral Challenge.
Holmgren AM, Miller KD, Cavanaugh SE, Rall GF., Free PMC Article | 01/23/2016 |
| BST-2 contributes to the emergence of neoplasia and malignant progression of breast cancer. BST-2 enhances cancer cell adhesion, anchorage-independency, migration, and invasion. | Bone marrow stromal antigen 2 expressed in cancer cells promotes mammary tumor growth and metastasis.
Mahauad-Fernandez WD, DeMali KA, Olivier AK, Okeoma CM., Free PMC Article | 11/14/2015 |
| BST-2 protects lymphoid tissues from Chikungunya virus (CHIKV) infection and regulates CHIKV-induced inflammatory response by the host. | Critical role for bone marrow stromal antigen 2 in acute Chikungunya virus infection.
Mahauad-Fernandez WD, Jones PH, Okeoma CM., Free PMC Article | 02/14/2015 |
| TLR4 and PI3K effects on BST-2 induction are at the level of transcription. | Phosphatidylinositol 3-kinase is involved in Toll-like receptor 4-mediated BST-2/tetherin regulation.
Jones PH, Okeoma CM. | 12/6/2014 |
| Tetherin acts as a modulator of the cell-mediated immune response against retrovirus infection in vivo. | Tetherin promotes the innate and adaptive cell-mediated immune response against retrovirus infection in vivo.
Li SX, Barrett BS, Heilman KJ, Messer RJ, Liberatore RA, Bieniasz PD, Kassiotis G, Hasenkrug KJ, Santiago ML., Free PMC Article | 08/23/2014 |
| These findings suggest that BST2 antagonism by Vpu is critical for efficient early viral expansion and dissemination during acute infection and as such is likely to confer HIV-1 increased transmission fitness. | Efficient BST2 antagonism by Vpu is critical for early HIV-1 dissemination in humanized mice.
Dave VP, Hajjar F, Dieng MM, Haddad É, Cohen ÉA., Free PMC Article | 07/12/2014 |
| These data suggest that overexpression of BST-2 in carcinoma tissues could not be attributed to interferons but to a yet to be determined factor that upregulates BST-2 once oncogenesis is initiated. | BST-2/tetherin is overexpressed in mammary gland and tumor tissues in MMTV-induced mammary cancer.
Jones PH, Mahauad-Fernandez WD, Madison MN, Okeoma CM., Free PMC Article | 11/16/2013 |
| Taken together, our results indicate that BST-2 is an important factor in the invasiveness and motility of tamoxifen-resistant breast cancer cells, and that its expression and activity are regulated by activated STAT3. | BST-2 is a potential activator of invasion and migration in tamoxifen-resistant breast cancer cells.
Yi EH, Yoo H, Noh KH, Han S, Lee H, Lee JK, Won C, Kim BH, Kim MH, Cho CH, Ye SK. | 08/31/2013 |
| BST-2 is a useful receptor to target with antigen, given its broad expression pattern and ability to access both MHCI and MHCII presentation pathways with relative efficiency. | Targeting antigen to bone marrow stromal cell-2 expressed by conventional and plasmacytoid dendritic cells elicits efficient antigen presentation.
Moffat JM, Segura E, Khoury G, Caminschi I, Cameron PU, Lewin SR, Villadangos JA, Mintern JD. | 05/4/2013 |
| A single nucleotide polymorphism in tetherin promotes retrovirus restriction in vivo. | A single nucleotide polymorphism in tetherin promotes retrovirus restriction in vivo.
Barrett BS, Smith DS, Li SX, Guo K, Hasenkrug KJ, Santiago ML., Free PMC Article | 07/14/2012 |
| find that tetherin markedly inhibits the replication of Moloney murine leukemia virus (Mo-MLV) and is required for the antiretroviral activity of IFNalpha to be fully manifested in vitro. | Tetherin is a key effector of the antiretroviral activity of type I interferon in vitro and in vivo.
Liberatore RA, Bieniasz PD., Free PMC Article | 06/12/2012 |
| These data provide evidence that BST-2 restricts mouse mammary tumor virus release from naturally infected cells and that BST-2 is an antiviral factor in vivo. | Bone marrow stromal cell antigen 2 (BST-2) restricts mouse mammary tumor virus (MMTV) replication in vivo.
Jones PH, Mehta HV, Maric M, Roller RJ, Okeoma CM., Free PMC Article | 05/19/2012 |
| These findings reflect involvement of BST2 in endocytosis and intracellular trafficking of viruses, viral nucleic acids, and Ags. | Cutting edge: paradoxical roles of BST2/tetherin in promoting type I IFN response and viral infection.
Swiecki M, Wang Y, Gilfillan S, Lenschow DJ, Colonna M., Free PMC Article | 04/21/2012 |