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    PRDX2 peroxiredoxin 2 [ Homo sapiens (human) ]

    Gene ID: 7001, updated on 29-Oct-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Knockdown of PRDX2 Inhibits the Proliferation, Growth, Migration, Invasion, and MMP9 Activity of Ewing's Sarcoma Cells Cultured In Vitro.

    Knockdown of PRDX2 Inhibits the Proliferation, Growth, Migration, Invasion, and MMP9 Activity of Ewing's Sarcoma Cells Cultured In Vitro.
    Xue R, Fan Z, An Y., Free PMC Article

    10/25/2024
    PRDX2 regulates stemness contributing to cisplatin resistance and metastasis in bladder cancer.

    PRDX2 regulates stemness contributing to cisplatin resistance and metastasis in bladder cancer.
    Li P, Wang W, Zhu B, Wang Y, Li J, Wang C, Wang C, Li Q.

    05/6/2024
    Implications and progression of peroxiredoxin 2 (PRDX2) in various human diseases.

    Implications and progression of peroxiredoxin 2 (PRDX2) in various human diseases.
    Balasubramanian P, Vijayarangam V, Deviparasakthi MKG, Palaniyandi T, Ravi M, Natarajan S, Viswanathan S, Baskar G, Wahab MRA, Surendran H.

    02/28/2024
    MiR-92a-2-5p suppresses esophageal squamous cell carcinoma cell proliferation and invasion by targeting PRDX2.

    MiR-92a-2-5p suppresses esophageal squamous cell carcinoma cell proliferation and invasion by targeting PRDX2.
    Zhan X, Li J, Zeng R, Lei L, Feng A, Yang Z.

    02/4/2024
    Silencing of peroxiredoxin 2 suppresses proliferation and Wnt/beta-catenin pathway, and induces senescence in hepatocellular carcinoma.

    Silencing of peroxiredoxin 2 suppresses proliferation and Wnt/β-catenin pathway, and induces senescence in hepatocellular carcinoma.
    Yang X, Xiang X, Xu G, Zhou S, An T, Huang Z., Free PMC Article

    01/10/2024
    Redox-stress response resistance (RRR) mediated by hyperoxidation of peroxiredoxin 2 in senescent cells.

    Redox-stress response resistance (RRR) mediated by hyperoxidation of peroxiredoxin 2 in senescent cells.
    Meng J, Wang Y, Lv Z, Qiao X, Ye A, Zhu Q, Chen C.

    10/28/2023
    Negative pressure wound therapy promotes wound healing of diabetic foot ulcers by up-regulating PRDX2 in wound margin tissue.

    Negative pressure wound therapy promotes wound healing of diabetic foot ulcers by up-regulating PRDX2 in wound margin tissue.
    Tang Y, Liu L, Jie R, Tang Y, Zhao X, Xu M, Chen M., Free PMC Article

    09/29/2023
    The Study of Overexpression of Peroxiredoxin-2 Reduces MPP[+]-Induced Toxicity in the Cell Model of Parkinson's Disease.

    The Study of Overexpression of Peroxiredoxin-2 Reduces MPP(+)-Induced Toxicity in the Cell Model of Parkinson's Disease.
    Liu M, Zuo S, Guo X, Peng J, Xing Y, Guo Y, Li C, Xing H., Free PMC Article

    05/24/2023
    Peroxiredoxin2 regulates trophoblast proliferation and migration through SPIB-HDAC2 pathway.

    Peroxiredoxin2 regulates trophoblast proliferation and migration through SPIB-HDAC2 pathway.
    Wu F, Tian F, Qin C, Qin X, Zeng W, Liu X, Chen C, Lin Y.

    01/14/2023
    ANXA2, SP17, SERPINA5, PRDX2 genes, and sperm DNA fragmentation differentially represented in male partners of infertile couples with normal and abnormal sperm parameters.

    ANXA2, SP17, SERPINA5, PRDX2 genes, and sperm DNA fragmentation differentially represented in male partners of infertile couples with normal and abnormal sperm parameters.
    Afsari M, Fesahat F, Talebi AR, Agarwal A, Henkel R, Zare F, Gül M, Iraci N, Cannarella R, Makki M, Anvari M, Sarcheshmeh AA, Talebi AH.

    10/22/2022
    Oxidative Stress Induced Cell Cycle Arrest: Potential Role of PRX-2 and GSTP-1 as Therapeutic Targets in Hepatocellular Carcinoma.

    Oxidative Stress Induced Cell Cycle Arrest: Potential Role of PRX-2 and GSTP-1 as Therapeutic Targets in Hepatocellular Carcinoma.
    Mohsin A, Haneef K, Ilyas A, Zarina S, Hashim Z.

    02/12/2022
    CircDIDO1 inhibits gastric cancer progression by encoding a novel DIDO1-529aa protein and regulating PRDX2 protein stability.

    CircDIDO1 inhibits gastric cancer progression by encoding a novel DIDO1-529aa protein and regulating PRDX2 protein stability.
    Zhang Y, Jiang J, Zhang J, Shen H, Wang M, Guo Z, Zang X, Shi H, Gao J, Cai H, Fang X, Qian H, Xu W, Zhang X., Free PMC Article

    01/29/2022
    Active hematopoiesis triggers exosomal release of PRDX2 that promotes osteoclast formation.

    Active hematopoiesis triggers exosomal release of PRDX2 that promotes osteoclast formation.
    Sadvakassova G, Tiedemann K, Steer KJD, Mikolajewicz N, Stavnichuk M, In-Kyung Lee I, Sabirova Z, Schranzhofer M, Komarova SV., Free PMC Article

    12/11/2021
    PRDX2 promotes the proliferation of colorectal cancer cells by increasing the ubiquitinated degradation of p53.

    PRDX2 promotes the proliferation of colorectal cancer cells by increasing the ubiquitinated degradation of p53.
    Wang W, Wei J, Zhang H, Zheng X, Zhou H, Luo Y, Yang J, Deng Q, Huang S, Fu Z., Free PMC Article

    11/6/2021
    Deficiency of peroxiredoxin 2 exacerbates angiotensin II-induced abdominal aortic aneurysm.

    Deficiency of peroxiredoxin 2 exacerbates angiotensin II-induced abdominal aortic aneurysm.
    Jeong SJ, Cho MJ, Ko NY, Kim S, Jung IH, Min JK, Lee SH, Park JG, Oh GT., Free PMC Article

    10/2/2021
    Modifying the resolving cysteine affects the structure and hydrogen peroxide reactivity of peroxiredoxin 2.

    Modifying the resolving cysteine affects the structure and hydrogen peroxide reactivity of peroxiredoxin 2.
    Peskin AV, Meotti FC, Kean KM, Göbl C, Peixoto AS, Pace PE, Horne CR, Heath SG, Crowther JM, Dobson RCJ, Karplus PA, Winterbourn CC., Free PMC Article

    09/11/2021
    Peroxiredoxin 2 oxidation reveals hydrogen peroxide generation within erythrocytes during high-dose vitamin C administration.

    Peroxiredoxin 2 oxidation reveals hydrogen peroxide generation within erythrocytes during high-dose vitamin C administration.
    Pearson AG, Pullar JM, Cook J, Spencer ES, Vissers MC, Carr AC, Hampton MB., Free PMC Article

    08/21/2021
    The critical role of peroxiredoxin-2 in colon cancer stem cells.

    The critical role of peroxiredoxin-2 in colon cancer stem cells.
    Peng L, Xiong Y, Wang R, Xiang L, Zhou H, Fu Z., Free PMC Article

    07/31/2021
    Reactive oxygen species-regulating proteins peroxiredoxin 2 and thioredoxin, and glyceraldehyde-3-phosphate dehydrogenase are differentially abundant in induced sputum from smokers with lung cancer or asbestos exposure.

    Reactive oxygen species-regulating proteins peroxiredoxin 2 and thioredoxin, and glyceraldehyde-3-phosphate dehydrogenase are differentially abundant in induced sputum from smokers with lung cancer or asbestos exposure.
    Rostila AM, Anttila SL, Lalowski MM, Vuopala KS, Toljamo TI, Lindström I, Baumann MH, Puustinen AM.

    07/10/2021
    PRDX2 plays an oncogenic role in esophageal squamous cell carcinoma via Wnt/beta-catenin and AKT pathways.

    PRDX2 plays an oncogenic role in esophageal squamous cell carcinoma via Wnt/β-catenin and AKT pathways.
    Feng AL, Han X, Meng X, Chen Z, Li Q, Shu W, Dai H, Zhu J, Yang Z.

    06/5/2021
    Celastrol induces ROS-mediated apoptosis via directly targeting peroxiredoxin-2 in gastric cancer cells.

    Celastrol induces ROS-mediated apoptosis via directly targeting peroxiredoxin-2 in gastric cancer cells.
    Chen X, Zhao Y, Luo W, Chen S, Lin F, Zhang X, Fan S, Shen X, Wang Y, Liang G., Free PMC Article

    05/29/2021
    PRDX2 Promotes the Proliferation and Metastasis of Non-Small Cell Lung Cancer In Vitro and In Vivo.

    PRDX2 Promotes the Proliferation and Metastasis of Non-Small Cell Lung Cancer In Vitro and In Vivo.
    Chen Y, Yang S, Zhou H, Su D., Free PMC Article

    05/8/2021
    PRDX2 removal inhibits the cell cycle and autophagy in colorectal cancer cells.

    PRDX2 removal inhibits the cell cycle and autophagy in colorectal cancer cells.
    Zheng X, Wei J, Li W, Li X, Wang W, Guo J, Fu Z., Free PMC Article

    04/24/2021
    Prdx2 Upregulation Promotes the Growth and Survival of Gastric Cancer Cells.

    Prdx2 Upregulation Promotes the Growth and Survival of Gastric Cancer Cells.
    Zhang S, He J, Tang M, Sun H.

    04/13/2021
    Prx II reduces oxidative stress and cell senescence in chondrocytes by activating the p16-CDK4/6-pRb-E2F signaling pathway.

    Prx II reduces oxidative stress and cell senescence in chondrocytes by activating the p16-CDK4/6-pRb-E2F signaling pathway.
    Shao JH, Fu QW, Li LX, Zhou R, Liu N, Peng JH, Chen Y.

    04/3/2021
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