| CYP19A1 Expression Is Controlled by mRNA Stability of the Upstream Transcription Factor AP-2gamma in Placental JEG3 Cells. | CYP19A1 Expression Is Controlled by mRNA Stability of the Upstream Transcription Factor AP-2γ in Placental JEG3 Cells.
Kotomura N, Shimono Y, Ishihara S. | 08/6/2024 |
| Tead4 and Tfap2c generate bipotency and a bistable switch in totipotent embryos to promote robust lineage diversification. | Tead4 and Tfap2c generate bipotency and a bistable switch in totipotent embryos to promote robust lineage diversification.
Zhu M, Meglicki M, Lamba A, Wang P, Royer C, Turner K, Jauhar MA, Jones C, Child T, Coward K, Na J, Zernicka-Goetz M., Free PMC Article | 06/24/2024 |
| Lineage regulators TFAP2C and NR5A2 function as bipotency activators in totipotent embryos. | Lineage regulators TFAP2C and NR5A2 function as bipotency activators in totipotent embryos.
Li L, Lai F, Liu L, Lu X, Hu X, Liu B, Lin Z, Fan Q, Kong F, Xu Q, Xie W. | 06/24/2024 |
| TFAP2C exacerbates psoriasis-like inflammation by promoting Th17 and Th1 cells activation through regulating TEAD4 transcription. | TFAP2C exacerbates psoriasis-like inflammation by promoting Th17 and Th1 cells activation through regulating TEAD4 transcription.
Zhang H, Ren C, Liu Q, Wang Q, Wang D. | 06/2/2023 |
| TFAP2C inhibits cell autophagy to alleviate myocardial ischemia/reperfusion injury by regulating miR-23a-5p/SFRP5/Wnt5a axis. | TFAP2C inhibits cell autophagy to alleviate myocardial ischemia/reperfusion injury by regulating miR-23a-5p/SFRP5/Wnt5a axis.
Zeng M, Wei X, He YL, Chen JX, Lin WT. | 05/19/2023 |
| KLF14/miR-1283/TFAP2C axis inhibits HER2-positive breast cancer progression via declining tumor cell proliferation. | KLF14/miR-1283/TFAP2C axis inhibits HER2-positive breast cancer progression via declining tumor cell proliferation.
Chen XZ, He WX, Luo RG, Xia GJ, Zhong JX, Chen QJ, Huang YY, Guan YX. | 03/21/2023 |
| Transcription factor AP-2 gamma/Kruppel-like factor 10 axis is involved in miR-3656-related dysfunction of endothelial cells in hypertension. | Transcription factor AP-2 gamma/Krüppel-like factor 10 axis is involved in miR-3656-related dysfunction of endothelial cells in hypertension.
Ren Y, Shi J, Liu S, Zhu W, Shao A, Qiao Y, Li Y, Liu Y, Cheng Y, Liu Y. | 03/13/2023 |
| HN1L/AP-2gamma/PLK1 signaling drives tumor progression and chemotherapy resistance in esophageal squamous cell carcinoma. | HN1L/AP-2γ/PLK1 signaling drives tumor progression and chemotherapy resistance in esophageal squamous cell carcinoma.
Zeng TT, Deng TH, Liu Z, Zhan JR, Ma YZ, Yan YY, Sun X, Zhu YH, Li Y, Guan XY, Li L., Free PMC Article | 12/17/2022 |
| Roles of activator protein-2 gamma in breast cancer: A narrative review (SANRA). | Roles of activator protein-2 gamma in breast cancer: A narrative review (SANRA).
Zhang Y, Mostafa AA, Sriboonvorakul N, Hu J., Free PMC Article | 10/15/2022 |
| Interaction of transcription factor AP-2 gamma with proto-oncogene PELP1 promotes tumorigenesis by enhancing RET signaling. | Interaction of transcription factor AP-2 gamma with proto-oncogene PELP1 promotes tumorigenesis by enhancing RET signaling.
Liu J, Liu Z, Li M, Tang W, Pratap UP, Luo Y, Altwegg KA, Li X, Zou Y, Zhu H, Sareddy GR, Viswanadhapalli S, Vadlamudi RK., Free PMC Article | 01/15/2022 |
| GATA transcription factors, SOX17 and TFAP2C, drive the human germ-cell specification program. | GATA transcription factors, SOX17 and TFAP2C, drive the human germ-cell specification program.
Kojima Y, Yamashiro C, Murase Y, Yabuta Y, Okamoto I, Iwatani C, Tsuchiya H, Nakaya M, Tsukiyama T, Nakamura T, Yamamoto T, Saitou M., Free PMC Article | 10/16/2021 |
| Fucosyltransferase 8 regulation and breast cancer suppression by transcription factor activator protein 2gamma. | Fucosyltransferase 8 regulation and breast cancer suppression by transcription factor activator protein 2γ.
Ma M, Guo D, Tan Z, Du J, Guan F, Li X., Free PMC Article | 08/21/2021 |
| Comprehensive analysis of the expression and prognosis for TFAP2 in human lung carcinoma. | Comprehensive analysis of the expression and prognosis for TFAP2 in human lung carcinoma.
Cheng C, Ai Z, Zhao L. | 07/3/2021 |
| METTL3 potentiates resistance to cisplatin through m(6) A modification of TFAP2C in seminoma. | METTL3 potentiates resistance to cisplatin through m(6) A modification of TFAP2C in seminoma.
Wei J, Yin Y, Zhou J, Chen H, Peng J, Yang J, Tang Y., Free PMC Article | 05/8/2021 |
| Functional genomics of AP-2alpha and AP-2gamma in cancers: in silico study. | Functional genomics of AP-2α and AP-2γ in cancers: in silico study.
Kołat D, Kałuzińska Ż, Orzechowska M, Bednarek AK, Płuciennik E., Free PMC Article | 05/8/2021 |
| MiR-29b-3p cooperates with miR-29c-3p to affect the malignant biological behaviors in T-cell acute lymphoblastic leukemia via TFAP2C/GPX1 axis. | MiR-29b-3p cooperates with miR-29c-3p to affect the malignant biological behaviors in T-cell acute lymphoblastic leukemia via TFAP2C/GPX1 axis.
Zhuang M, Chaolumen Q, Li L, Chen B, Su Q, Yang Y, Zhang X. | 01/9/2021 |
| TFAP2C regulates carbonic anhydrase XII in human breast cancer. | TFAP2C regulates carbonic anhydrase XII in human breast cancer.
Franke CM, Gu VW, Grimm BG, Cassady VC, White JR, Weigel RJ, Kulak MV. | 11/28/2020 |
| Extracellular matrix anisotropy is determined by TFAP2C-dependent regulation of cell collisions. | Extracellular matrix anisotropy is determined by TFAP2C-dependent regulation of cell collisions.
Park D, Wershof E, Boeing S, Labernadie A, Jenkins RP, George S, Trepat X, Bates PA, Sahai E., Free PMC Article | 11/28/2020 |
| A TFAP2C Gene Signature Is Predictive of Outcome in HER2-Positive Breast Cancer. | A TFAP2C Gene Signature Is Predictive of Outcome in HER2-Positive Breast Cancer.
Wu VT, Kiriazov B, Koch KE, Gu VW, Beck AC, Borcherding N, Li T, Addo P, Wehrspan ZJ, Zhang W, Braun TA, Brown BJ, Band V, Band H, Kulak MV, Weigel RJ., Free PMC Article | 11/21/2020 |
| AP2gamma mediated downregulation of LINC00511 suppresses trophoblast invasion by regulating miR-29b-3p/ Cyr61 axis. | AP2γ mediated downregulation of lncRNA LINC00511 as a ceRNA suppresses trophoblast invasion by regulating miR-29b-3p/Cyr61 axis.
Quan X, Zhao M, Yang X, Zhu Y, Tian X. | 04/25/2020 |
| TFAP2C primes the surface ectoderm chromatin landscape and induces p63 expression and binding sites, thus allowing maturation factor p63 to positively autoregulate its own expression and close a subset of the TFAP2C-initiated surface ectoderm program. | TFAP2C- and p63-Dependent Networks Sequentially Rearrange Chromatin Landscapes to Drive Human Epidermal Lineage Commitment.
Li L, Wang Y, Torkelson JL, Shankar G, Pattison JM, Zhen HH, Fang F, Duren Z, Xin J, Gaddam S, Melo SP, Piekos SN, Li J, Liaw EJ, Chen L, Li R, Wernig M, Wong WH, Chang HY, Oro AE., Free PMC Article | 03/28/2020 |
| Molecular network of transcription factor AP-2 alpha (AP-2alpha) and transcription factor AP-2 gamma (AP-2gamma) and other molecules may clarify the atypical molecular mechanisms occurring during carcinogenesis [Review]. | The biological characteristics of transcription factors AP-2α and AP-2γ and their importance in various types of cancers.
Kołat D, Kałuzińska Ż, Bednarek AK, Płuciennik E., Free PMC Article | 02/22/2020 |
| deleting the TFAP2C-bound naive enhancer at the OCT4 locus (also called POU5F1) results in impaired OCT4 expression and a negative effect on human primordial germ cells-like cell identity. | The TFAP2C-Regulated OCT4 Naive Enhancer Is Involved in Human Germline Formation.
Chen D, Liu W, Zimmerman J, Pastor WA, Kim R, Hosohama L, Ho J, Aslanyan M, Gell JJ, Jacobsen SE, Clark AT., Free PMC Article | 12/7/2019 |
| Our findings indicate that TFAP2C may serve as a novel prognostic factor in CRC patients, and a therapeutic target for the treatment of CRC, suggesting that silencing TFAP2C in combination with 5-FU may be an effective therapeutic strategy to improve survival in CRC patients. | TFAP2C promotes stemness and chemotherapeutic resistance in colorectal cancer via inactivating hippo signaling pathway.
Wang X, Sun D, Tai J, Chen S, Yu M, Ren D, Wang L., Free PMC Article | 05/11/2019 |
| survival analysis demonstrated that high miR-10a-5p expression levels and low TFAP2C expression levels were both independent adverse prognostic factors in patients with PDAC. | MiR-10a-5p targets TFAP2C to promote gemcitabine resistance in pancreatic ductal adenocarcinoma.
Xiong G, Huang H, Feng M, Yang G, Zheng S, You L, Zheng L, Hu Y, Zhang T, Zhao Y., Free PMC Article | 05/11/2019 |