| TGFA expression is associated with poor prognosis and promotes the development of cervical cancer. | TGFA expression is associated with poor prognosis and promotes the development of cervical cancer.
Ma X, Zheng J, He K, Wang L, Wang Z, Wang K, Liu Z, San Z, Zhao L, Wang L., Free PMC Article | 02/9/2024 |
| EGF, TGF-alpha and Amphiregulin Differently Regulate Endometrium-Derived Mesenchymal Stromal/Stem Cells. | EGF, TGF-α and Amphiregulin Differently Regulate Endometrium-Derived Mesenchymal Stromal/Stem Cells.
Kamentseva RS, Kharchenko MV, Gabdrahmanova GV, Kotov MA, Kosheverova VV, Kornilova ES., Free PMC Article | 09/18/2023 |
| CircRTN1 acts as a miR-431-5p sponge to promote thyroid cancer progression by upregulating TGFA. | CircRTN1 acts as a miR-431-5p sponge to promote thyroid cancer progression by upregulating TGFA.
Gao Y, Wang Y, Xu L, Xie X, Zhu L, Wang F. | 12/10/2022 |
| Autocrine TGF-alpha is associated with Benzo(a)pyrene-induced mucus production and MUC5AC expression during allergic asthma. | Autocrine TGF-alpha is associated with Benzo(a)pyrene-induced mucus production and MUC5AC expression during allergic asthma.
Sun Y, Miao X, Zhu L, Liu J, Lin Y, Xiang G, Wu X, Wang X, Ni Z, Li S. | 09/17/2022 |
| Genetic markers for non-syndromic orofacial clefts in populations of European ancestry: a meta-analysis. | Genetic markers for non-syndromic orofacial clefts in populations of European ancestry: a meta-analysis.
Slavec L, Karas Kuželički N, Locatelli I, Geršak K., Free PMC Article | 03/12/2022 |
| The Aryl Hydrocarbon Receptor-Dependent TGF-alpha/VEGF-B Ratio Correlates With Disease Subtype and Prognosis in Multiple Sclerosis. | The Aryl Hydrocarbon Receptor-Dependent TGF-α/VEGF-B Ratio Correlates With Disease Subtype and Prognosis in Multiple Sclerosis.
Cirac A, Tsaktanis T, Beyer T, Linnerbauer M, Andlauer T, Grummel V, Nirschl L, Loesslein L, Quintana FJ, Hemmer B, Rothhammer V., Free PMC Article | 03/5/2022 |
| Altered proTGFalpha/cleaved TGFalpha ratios offer new therapeutic strategies in renal carcinoma. | Altered proTGFα/cleaved TGFα ratios offer new therapeutic strategies in renal carcinoma.
García-Alonso S, Romero-Pérez I, Gandullo-Sánchez L, Chinchilla L, Ocaña A, Montero JC, Pandiella A., Free PMC Article | 01/15/2022 |
| LncRNA LINC00857 strengthens the malignancy behaviors of pancreatic adenocarcinoma cells by serving as a competing endogenous RNA for miR-340-5p to upregulate TGFA expression. | LncRNA LINC00857 strengthens the malignancy behaviors of pancreatic adenocarcinoma cells by serving as a competing endogenous RNA for miR-340-5p to upregulate TGFA expression.
Li T, Zhao H, Zhou H, Geng T., Free PMC Article | 10/23/2021 |
| IRF6, MSX1, TGFA, dental anomalies, and skeletal malocclusion. | IRF6, MSX1, TGFA, dental anomalies, and skeletal malocclusion.
Fernandez CCA, Pereira CVCA, Ferreira FFCF, Maciel JVB, Modesto A, Costa MC, Vieira AR. | 10/9/2021 |
| MicroRNA-374b inhibits breast cancer progression through regulating CCND1 and TGFA genes. | MicroRNA-374b inhibits breast cancer progression through regulating CCND1 and TGFA genes.
Liu Y, Zhang A, Bao PP, Lin L, Wang Y, Wu H, Shu XO, Liu A, Cai Q., Free PMC Article | 10/2/2021 |
| Association of rs2862851 in TGFA Gene with Peripheral TGFA Levels and the Severity of Knee Osteoarthritis in the Han Chinese Population. | Association of rs2862851 in TGFA Gene with Peripheral TGFA Levels and the Severity of Knee Osteoarthritis in the Han Chinese Population.
Cui G, Liu D, Wei R, Wu J, Liu R, Wang K. | 07/17/2021 |
| Ovarian cancer cells direct monocyte differentiation through a non-canonical pathway. | Ovarian cancer cells direct monocyte differentiation through a non-canonical pathway.
Fogg KC, Miller AE, Li Y, Flanigan W, Walker A, O'Shea A, Kendziorski C, Kreeger PK., Free PMC Article | 04/24/2021 |
| loss of circRNA_0084043 depressed HG-induced damage via sponging miR-140-3p and regulating TGFA. | circRNA_0084043 contributes to the progression of diabetic retinopathy via sponging miR-140-3p and inducing TGFA gene expression in retinal pigment epithelial cells.
Li Y, Cheng T, Wan C, Cang Y. | 05/23/2020 |
| Our results have shown that high levels of TGF-alpha and Ki-67 are associated with shorter PFS in patients with chordoma. We also identified TGF-alpha as a potential novel biomarker for predicting prognosis for patients with skull base chordoma. | Predictive Value of Transforming Growth Factor-α and Ki-67 for the Prognosis of Skull Base Chordoma.
Zhang S, Bai J, Li M, Zhai Y, Wang S, Liu Q, Li C, Gui S, Zhang Y. | 01/25/2020 |
| Our study indicates that the TGFA gene polymorphism might be associated with nonsyndromic CL/P susceptibility. | Transforming Growth Factor Alpha Taq I Polymorphisms and Nonsyndromic Cleft Lip and/or Palate Risk: A Meta-Analysis.
Yan C, Deng-Qi H, Li-Ya C, Mang Y, Ke-Hu Y. | 10/12/2019 |
| our study found that spherical silica nanoparticles (SiNPs) promoted the proliferation and EMT of BEAS-2B cells by inducing the release of TGF-a from THP-1 cells. | Blockage of TGF-α Induced by Spherical Silica Nanoparticles Inhibits Epithelial-Mesenchymal Transition and Proliferation of Human Lung Epithelial Cells.
Li Y, Li H, Duan Y, Cai X, You D, Zhou F, Yang C, Tuo X, Liu Z., Free PMC Article | 07/27/2019 |
| TGFalpha modulates epithelial-mesenchymal transition (EMT) markers and NFkappaB signaling pathway in colon cancer cells. | Transforming growth factor alpha promotes tumorigenesis and regulates epithelial-mesenchymal transition modulation in colon cancer.
Yu CY, Chang WC, Zheng JH, Hung WH, Cho EC. | 05/18/2019 |
| The frequency of A allele in all the case groups and control groups was 50% and 2%, respectively, in the cleft lip cases was 50%, and in the cleft lip and palate cases was 50%. There was a statistically significant difference between genotype frequency of TGFalpha/HinfI polymorphisms in nsCL cases, nsCL+P cases, and nsCL +/- P cases compared with controls (p = 0.029, p = 0.024, and p = 0.0365, respectively). | TGFα/HinfI Polymorphisms Contribute to Nonsyndromic Cleft Lip and Palate in Turkish Patients.
Derelli Tufekci E, Ozdiler E, Altug AT, Sancak O, Ozdiler O, Tastan H. | 01/5/2019 |
| The abnormally elevated expression of EGF and TGF-alpha are closely associated with the occurrence and development of chronic pancreatitis and pancreatic cancer | Expression and clinical significance of EGF and TGF-α in chronic pancreatitis and pancreatic cancer.
Hao C, Li Z, Zhang X, Zhang H, Shang H, Bao J, Wang H. | 12/1/2018 |
| MiR-199a-5p may mediate cleft lip with or without cleft palate by regulating key target gene TGFA. | Identification of key genes in cleft lip with or without cleft palate regulated by miR-199a-5p.
Chen G, Li MX, Wang HX, Hong JW, Shen JY, Wang Q, Shi QM, Ge X, Ding Z, Zhang JP, Xu LC. | 10/20/2018 |
| this study demonstrated that TP73-AS1 regulated Colorectal cancer (CRC)progression by acting as a competitive endogenous RNA to sponge miR-194 to modulate the expression of TGFa | Long non-coding RNA TP73-AS1 sponges miR-194 to promote colorectal cancer cell proliferation, migration and invasion via up-regulating TGFα.
Cai Y, Yan P, Zhang G, Yang W, Wang H, Cheng X. | 10/20/2018 |
| There was evidence suggestive of gene-gene joint-effects between MTHFR-TGFA for nsCP but not for nsCL+/-P. | Genetic Interactions in Nonsyndromic Orofacial Clefts in Europe-EUROCRAN Study.
Mossey PA, Little J, Steegers-Theunissen R, Molloy A, Peterlin B, Shaw WC, Johnson C, FitzPatrick DR, Franceschelli P, Rubini M. | 07/14/2018 |
| TGFA TaqI polymorphism was not associated with the risk of nonsyndromic cleft lip and/or palate in Iranian children. | Association Study of Transforming Growth Factor Alpha TaqI Polymorphism and the Risk of Cleft Lip and/or Palate in an Iranian Population.
Bagheri F, Ebadifar A, Khorram Khorshid HR, Kamali K. | 06/23/2018 |
| We identi fi ed a signi fi cant association between the SNP rs2862851 and disease status of knee Osteoarthritis. Allelic analyses showed that the T allele of this SNP signi fi cantly elevated the risks of Osteoarthritis. Haplotype-based analyses have also identi fi ed a strong association signal between one haplotype block, including rs2862851, and the disease status of knee Osteoarthritis. | Association of Common Variants in TGFA with Increased Risk of Knee Osteoarthritis Susceptibility.
Cui G, Wei R, Liu D, Yang H, Wu J, Fan L, Wang K. | 02/10/2018 |
| Results suggest a long non-coding RNA MALAT1/MIR376A/transforming growth factor alpha (TGFA) axis mediates osteosarcoma (OS) cell proliferation and tumor progression. | MALAT1 promotes osteosarcoma development by targeting TGFA via MIR376A.
Luo W, He H, Xiao W, Liu Q, Deng Z, Lu Y, Wang Q, Zheng Q, Li Y., Free PMC Article | 02/3/2018 |