| Polymorphism of Transforming Growth Factor TGFB and Its Receptors TGFBRI, TGFBRII, TGFBRIIII Genes in Western Siberia Patients with Open-Angle Glaucoma. | Polymorphism of Transforming Growth Factor TGFB and Its Receptors TGFBRI, TGFBRII, TGFBRIIII Genes in Western Siberia Patients with Open-Angle Glaucoma.
Shevchenko AV, Prokofiev VF, Konenkov VI, Chernykh VV, Trunov AN. | 06/17/2024 |
| Exosomal miR-103a-3p from Crohn's Creeping Fat-Derived Adipose-Derived Stem Cells Contributes to Intestinal Fibrosis by Targeting TGFBR3 and Activating Fibroblasts. | Exosomal miR-103a-3p from Crohn's Creeping Fat-Derived Adipose-Derived Stem Cells Contributes to Intestinal Fibrosis by Targeting TGFBR3 and Activating Fibroblasts.
Qian W, Xu Y, Wen W, Huang L, Guo Z, Zhu W, Li Y. | 08/23/2023 |
| MEX3B inhibits collagen production in eosinophilic nasal polyps by downregulating epithelial cell TGFBR3 mRNA stability. | MEX3B inhibits collagen production in eosinophilic nasal polyps by downregulating epithelial cell TGFBR3 mRNA stability.
Liu JX, Chen AN, Yu Q, Shi KT, Liu YB, Guo CL, Wang ZZ, Yao Y, Pan L, Lu X, Xu K, Wang H, Zeng M, Liu C, Schleimer RP, Wu N, Liao B, Liu Z., Free PMC Article | 05/9/2023 |
| Does TGFBR3 Polymorphism Increase the Risk of Silent Cerebral Infarction in Egyptian Children with Sickle Cell Disease? | Does TGFBR3 Polymorphism Increase the Risk of Silent Cerebral Infarction in Egyptian Children with Sickle Cell Disease?
Hassab H, Hanafi M, Elbeheiry A, Hassan M, Chazli YE., Free PMC Article | 01/21/2023 |
| Altered Endometrial Expression of alpha-Inhibin Subunit and Its Co-Receptor Betaglycan in Infertile Women with Endometriosis. | Altered Endometrial Expression of α-Inhibin Subunit and Its Co-Receptor Betaglycan in Infertile Women with Endometriosis.
Dela Cruz C, Vilamil QT, Casalechi M, Rezende CP, Assis WA, Del Puerto HL, Abrão MS, Reis FM. | 10/15/2022 |
| TGFBR3 supports anoikis through suppressing ATF4 signaling. | TGFBR3 supports anoikis through suppressing ATF4 signaling.
Hsu YJ, Yin YJ, Tsai KF, Jian CC, Liang ZW, Hsu CY, Wang CC. | 09/3/2022 |
| Transforming Growth Factor Beta Receptor 3 (TGFBR3)-Associated Membranous Nephropathy. | Transforming Growth Factor Beta Receptor 3 (TGFBR3)-Associated Membranous Nephropathy.
Caza TN, Hassen SI, Kenan DJ, Storey A, Arthur JM, Herzog C, Edmondson RD, Bourne TD, Beck LH Jr, Larsen CP., Free PMC Article | 04/16/2022 |
| Transforming Growth Factor Beta Receptor 3 Haplotypes in Sickle Cell Disease Are Associated with Lipid Profile and Clinical Manifestations. | Transforming Growth Factor Beta Receptor 3 Haplotypes in Sickle Cell Disease Are Associated with Lipid Profile and Clinical Manifestations.
Santiago RP, Figueiredo CVB, Fiuza LM, Yahouédéhou SCMA, Oliveira RM, Aleluia MM, Carvalho SP, Fonseca CA, Nascimento VML, Rocha LC, Guarda CC, Gonçalves MS., Free PMC Article | 10/2/2021 |
| Up-regulation of TbetaRIII facilitates the osteogenesis of supraspinous ligament-derived fibroblasts from patients with ankylosing spondylitis. | Up-regulation of TβRIII facilitates the osteogenesis of supraspinous ligament-derived fibroblasts from patients with ankylosing spondylitis.
Zhang Y, Chen WG, Yang SZ, Qiu H, Hu X, Qiu YY, Wen X, Zhou Y, Chu TW., Free PMC Article | 09/25/2021 |
| ALK1 regulates the internalization of endoglin and the type III TGF-beta receptor. | ALK1 regulates the internalization of endoglin and the type III TGF-β receptor.
Tazat K, Pomeraniec-Abudy L, Hector-Greene M, Szilágyi SS, Sharma S, Cai EM, Corona AL, Ehrlich M, Blobe GC, Henis YI., Free PMC Article | 09/18/2021 |
| A tumor-promoting role for soluble TbetaRIII in glioblastoma. | A tumor-promoting role for soluble TβRIII in glioblastoma.
Burghardt I, Schroeder JJ, Weiss T, Gramatzki D, Weller M., Free PMC Article | 09/11/2021 |
| TGFBR3 Polymorphisms (rs1805110 and rs7526590) Are Associated with Laboratory Biomarkers and Clinical Manifestations in Sickle Cell Anemia. | TGFBR3 Polymorphisms (rs1805110 and rs7526590) Are Associated with Laboratory Biomarkers and Clinical Manifestations in Sickle Cell Anemia.
Santiago RP, Figueiredo CVB, Fiuza LM, Yahouédéhou SCMA, Oliveira RM, Aleluia MM, Carvalho SP, Fonseca CA, Nascimento VML, Rocha LC, Guarda CC, Gonçalves MS., Free PMC Article | 07/31/2021 |
| TGFBR3 is an independent unfavourable prognostic marker in oesophageal squamous cell cancer and is positively correlated with Ki-67. | TGFBR3 is an independent unfavourable prognostic marker in oesophageal squamous cell cancer and is positively correlated with Ki-67.
Zhang X, Chen Y, Li Z, Han X, Liang Y., Free PMC Article | 03/6/2021 |
| Exploring new genetic variants within COL5A1 intron 4-exon 5 region and TGF-beta family with risk of anterior cruciate ligament ruptures. | Exploring new genetic variants within COL5A1 intron 4-exon 5 region and TGF-β family with risk of anterior cruciate ligament ruptures.
Laguette MN, Barrow K, Firfirey F, Dlamini S, Saunders CJ, Dandara C, Gamieldien J, Collins M, September AV. | 12/12/2020 |
| these results suggest that the clustered miR-23b-3p and miR-27b-3p consistently promote atrial fibrosis by targeting TGFBR3 to activate Smad3 signalling in HAFs, suggesting that miR-23b-3p and miR-27b-3p are potential therapeutic targets for atrial fibrosis | Novel role of the clustered miR-23b-3p and miR-27b-3p in enhanced expression of fibrosis-associated genes by targeting TGFBR3 in atrial fibroblasts.
Yang Z, Xiao Z, Guo H, Fang X, Liang J, Zhu J, Yang J, Li H, Pan R, Yuan S, Dong W, Zheng XL, Wu S, Shan Z., Free PMC Article | 07/25/2020 |
| We found that an SNP - rs1131243 on the TGF-betaR3 gene - is significantly related to the risk of Acute Rejection in renal transplant recipients but does not influence the severity of Acute Rejection | A Single-Nucleotide Polymorphism (rs1131243) of the Transforming Growth Factor Beta Signaling Pathway Contributes to Risk of Acute Rejection in Chinese Renal Transplant Recipients.
Zheng M, Yang H, Li W, Zhou J, Wei J, Wang Z, Guo M, Chen H, Sun L, Han Z, Tao J, Ju X, Tan R, Wei J, Gu M., Free PMC Article | 05/23/2020 |
| hsa_circ_0042666 regulated laryngeal squamous cell carcinoma cell proliferation and invasion by miR-223/TGFBR3 axis. | Hsa_circ_0042666 inhibits proliferation and invasion via regulating miR-223/TGFBR3 axis in laryngeal squamous cell carcinoma.
Wei Z, Chang K, Fan C. | 02/29/2020 |
| findings suggest a betaglycan-Wnt5a circuit represents an attractive vulnerability to ameliorate prostate cancer-induced osteogenesis | Betaglycan drives the mesenchymal stromal cell osteogenic program and prostate cancer-induced osteogenesis.
Cook LM, Frieling JS, Nerlakanti N, McGuire JJ, Stewart PA, Burger KL, Cleveland JL, Lynch CC., Free PMC Article | 02/29/2020 |
| TGFBR3 is targeted by MiR-501 which binds to its 3'UTR. Pancreatic ductal adenocarcinoma (PDAC) cells presented with down-regulated TGFBR3 expression by MiR-501 through the TGF-beta signaling pathway. | Macrophage-derived exosomal microRNA-501-3p promotes progression of pancreatic ductal adenocarcinoma through the TGFBR3-mediated TGF-β signaling pathway.
Yin Z, Ma T, Huang B, Lin L, Zhou Y, Yan J, Zou Y, Chen S., Free PMC Article | 01/18/2020 |
| A dormancy mechanism by which DTCs are induced into a dormant state through TGFbetaRIII-p38MAPK-pS249/pT252-RB signaling. | Osteoblast-Secreted Factors Mediate Dormancy of Metastatic Prostate Cancer in the Bone via Activation of the TGFβRIII-p38MAPK-pS249/T252RB Pathway.
Yu-Lee LY, Yu G, Lee YC, Lin SC, Pan J, Pan T, Yu KJ, Liu B, Creighton CJ, Rodriguez-Canales J, Villalobos PA, Wistuba II, de Nadal E, Posas F, Gallick GE, Lin SH., Free PMC Article | 06/15/2019 |
| Low TGFBR3 expression is associated with progression of lung cancer. | Upregulated lncRNA ADAMTS9-AS2 suppresses progression of lung cancer through inhibition of miR-223-3p and promotion of TGFBR3.
Liu C, Yang Z, Deng Z, Zhou Y, Gong Q, Zhao R, Chen T. | 06/1/2019 |
| also observed that the promotion of epithelial-to-mesenchymal transition by miR-19a and miR-424 was mediated by the inhibition of TGFBR3 | miR-19a and miR-424 target TGFBR3 to promote epithelial-to-mesenchymal transition and migration of tongue squamous cell carcinoma cells.
Li D, Liu K, Li Z, Wang J, Wang X., Free PMC Article | 06/1/2019 |
| Loss of TGFBR3 endows clear cell renal cell carcinoma cells with multiple metastatic abilities through TGF-beta-dependent and independent pathways. | Decreased TGFBR3/betaglycan expression enhances the metastatic abilities of renal cell carcinoma cells through TGF-β-dependent and -independent mechanisms.
Nishida J, Miyazono K, Ehata S., Free PMC Article | 03/16/2019 |
| We suggest that TGFBR3 protein expression is involved in up-regulated TGF-beta signaling in Marfan syndrome patients with a dominant negative FBN1 gene mutation. | Betaglycan (TGFBR3) up-regulation correlates with increased TGF-β signaling in Marfan patient fibroblasts in vitro.
Groeneveld ME, Bogunovic N, Musters RJP, Tangelder GJ, Pals G, Wisselink W, Micha D, Yeung KK. | 08/18/2018 |
| describe a detailed characterization of TbetaRIII expression in lymphocyte subpopulations demonstrating that this co-receptor is significantly expressed in T but not B lymphocytes and among them, preferentially expressed on naive and central memory T cells | TβRIII is induced by TCR signaling and downregulated in FoxP3(+) regulatory T cells.
Ortega-Francisco S, de la Fuente-Granada M, Alvarez Salazar EK, Bolaños-Castro LA, Fonseca-Camarillo G, Olguin-Alor R, Alemán-Muench GR, López-Casillas F, Raman C, García-Zepeda EA, Soldevila G. | 11/18/2017 |